@TOME V3
(Feb 2022)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Screening

Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : ATM_HUMAN: (2020-09-04 )
MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAVFRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQELLNYIMDTVKDSSNGAIYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFRLYLKPSQDVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSSGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEKGAYESTKWRSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVFNEDTRSLEISQSYTTTQRESSDYSVPCKRKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLISKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVCCLTLALTTSIVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILHSNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEELSFSEVEELFLQTTFDKMDFLTIVRECGIEKHQSSIGFSVHQNLKESLDRCLLGLSEQLLNNYSSEITNSETLVRCSRLLVGVLGCYCYMGVIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIGSLRNMMQLCTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSLASFIKKPFDRGEVESMEDDTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDMLKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEYPLPMEDVLELLKPLSNVCSLYRRDQDVCKTILNHVLHVVKNLGQSNMDSENTRDAQGQFLTVIGAFWHLTKERKYIFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLADNHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRKSVLLTLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSETFGYRRLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLIPHLVIRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYDMLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGDLDPAPNPPHFPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRILKIYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQVCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDNENLYITIKLLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLFEDKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNILATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSENHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRNLLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQKRPSSGTIFNDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEAMWGKALVTYDLETAIPSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHYQAAWRNMQWDHCTSVSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCKRSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRVCGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100.......110....-...120.......130-.........140.......150....---...160.......170.....-..180.......190.---......200.......210.......220..-......230.......240.......250.......260......-.-270.......280....---...290-........300.......310.......320.----.---------..--.--.----.-330.......340.---------......350.......360.......370.......380.......390-----.......400........410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.....------..520...-....530.......540.......550.......560.....-..570.......580....-...590.......600.......----610.......620.......630...-....640.......650.......660.......670.......-680.......690...---..-..700--........710.......720.......730.--......740.......750.......760.......770..-.....780.......790.......800.....-.----.810.......820.......830....--.-.-.840.......850.......860.......870.......880.....-..890.......900--........910.......920.......930.......940.......950.......---960.......970.......980.........990-----.........1000......1010......1020....-..1030......1040......1050-.......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160...-...-1170......1180..---.....1190......1200......1210......1220..-...----------------------------.1230......1240......1250......1260---......1270.......1280-----.........1290......1300......1310......1320.---.....--1330.......1340......1350..--....----1360-.--------.-.......--1370.....--.1380----....--...1390......1400......1410......1420.....-.---1430......1440......1450.......1460......1470......1480......1490......1500......1510..----....1520......1530--.--------......1540......1550....--..1560...-----...1570.------.....1580......1590.......1600......1610......1620.....--.1630---------..-----------....1640......1650......1660......1670......1680......1690......1700--.--.....1710....-.-.1720-.-.....1730......1740.---------.----------------..-.---.1750.......1760...-----...1770......1780......1790.....-.1800......1810......--1820......1830.-.....1840......1850-...--.---...1860......1870......1880......1890......1900......1910......1920.-------.-----.------------...1930..-------....1940......1950......1960......1970......1980......1990......2000......2010......2020...--.-..--2030.-.-....-.2040.....----.2050....-----------.---.------2060----.......2070......2080...-...2090.......2100......2110.....-----.--------2120......2130..-..-----.-----.2140......2150......2160.--.-....2170......2180......2190----.----.--.....2200......2210......2220......2230......2240---.--......2250......2260......2270......2280.-----..-----------...---2290......2300.-......2310......2320-------..-.------....2330......2340......----2350.....--.2360..-....2370......2380......2390......---------2400-----------......2410.--.....2420......2430.-....---.2440......2450......2460......2470...-..-.2480..-..-....2490....-------------------..2500......2510......2520......2530......2540......2550......2560........2570.....-.2580......2590.-..----..---.2600......2610-.-----.....-------.------------.2620-----------------........-------------------------------------2630--------------------------.------.--------------------..------------------------------------..-..2640---.-------------.-.--------------------.--.---.-----------..---------------------------2650------------------------.------...------------------.----.----------.-.-----.2660.-----.------.--...2670-.---....-------.---.2680......2690-.-.....2700......2710.....--.--2720......2730......2740......2750......2760......2770......2780--......2790-.......-2800--..-.-...------2810......2820..-...-.--2830......2840......2850......2860......2870......2880......2890-----------..---------..---.-.-2900.......2910......2920......2930......2940......2950......2960......2970.....--.2980...-.--..2990.......3000......3010......3020----.--.......3030......3040......3050...
(Atome) (Ident) (Tito) (Num) (QMean) (pKd) (pKd) (Uniprot) MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAVFRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLK-CQELLNYIMDTVKD---SSNGAIYGADCSNILLKDILSVRKYW---CEISQQQWLELFSVYFRLYLK-PSQDVHRVLVARIIHA---VTKGCCSQTDGLNSKFLDFFSKAIQCAR-QE-KSSSGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQ-H-RLNDSLKEVIIELFQLQ---IYIHH--PKGAKTQEKGAYESTKWRSILYNLYDLLVNEI----S---------HI--G--S----R-GKYSSGFRNIAVKE---------NLIELMADICHQVFNEDTRSLEISQSYTTTQRESSDYSVPCKRKKIELG-----WEVIKDHLQ-KSQNDFDLVPWLQIATQLISKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLV------EVDREFWK-LFTGSACRPSCPAVCCLTLALTTSIVPGTVKMGIEQNMCEVN-RSFSLKESIMKWLLFYQLE-GDLENSTEVPPILHSNFPHLVLE----KILVSLTMKNCKAAMNFFQSVPECEH-HQKDKEELSFSEVEELFLQTTFDKMDFLTIVRECGIEKHQSSIG-FSVHQNLKESLDRCLL---GL-SEQL---LNNYSSEITNSETLVRCSRLLVGVLGCYCYMG--VIAEEEAYKSELFQKAKSLMQCAGESITLFKNKTNEEFRIG-SLRNMMQLCTRCLSNCTKKSPNKIASGFFLRLL-T----SKLMNDIADICKSLASFIKKPFDRGEVE--S-M-EDDTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAE-EYLSKQDLLFLDML---KFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLEPTKSLHLHMYLMLLKELPGEEY---PLPMEDVLELLKPLSNVCSLY--RRDQDVCKTI-------LNHVLHVVKNLGQSNMDSENTRDAQGQFLTVIGAFWH-LTKERKYIFSVRMALVNCLKTLLE-A-DPYSKWAILNVMGKDFPVNEVFTQFLADNHHQVRMLAAESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRKSVLLTLIAVVLSCSP-ICE-KQALFALCKSVKE-NG---LEPHLVKKVLEKVSETFGYRRLEDFMASHLDYLVLEWLNLQ-DTE----------------------------YNLSSFPFILLNYTNIEDFYRSCYKVLIPHLVIRS---HFDEVKS-IANQIQEDWK--------SLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATKVYDMLKS---ENLLG--KQ-IDHLFISNLPEIVVELLMTLHEPA--NSSA----S----Q--------S-TDLCDFS--GDLDPAPNP--PHFP-----SHVI--KATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAE-T---NNVYKKHRILKIYHLFVSLLLKD-IKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQVCQTAVTYCKDALEN----HLHVIVGTLIPLVYEQV---E--------VQKQVLDLLKYLVIDNKDNENLYI--TIKLLDPFP-----DHVVFKDL------RITQQKIKYSRGPFSLL-EEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQM--VDIMR---------AS-----------QDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLF--E--DKELQWTFIMLTY-L-NNTLV-E-DCVKVRSAAVTCLKNILATK---------T----------------GH-S---FWEI-YKMTTDPMLAYLQP-----FRTSRKKFLEVPRFDKENPFEGLDDINLWIPL-SENHDIWIKTLTCAFLDSGGT--KCEILQLLKPMCEVK-TDFCQTVLPYLIHDILLQ--DTN--E---SWRNLLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQKRPSS-------G-----T------------IFNDAFWLD-------LNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKM--L-QP--I-TRL-R-TYEH-EAMWGKALVT----YDLETAIPS-----------S---T------RQA-----GIIQALQNLGLCHILSVYLKGLDY-ENKD-WCPELEELHYQAAWRNMQWDHCTSVSKE-----V--------EGTSYHESLYNALQSL-RD-----R-----EFSTFYESLKYARVKEVEEMCKRSLE--S-VYSLYPTLSRLQAIGELESIGELFSRS-----V----T--HRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNS----Q--RECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSV-----SC-----------GVS---EWQLEEAQVFWAK-K-EQSLALSILKQMIKKLDAS--------CA-A------NNPSLKLTYTECLRVCGNWLAETC----LENPAVIMQ--TYLEKAV-EVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQ---------RIEN-----------YMKSSEFENKQ--ALLKRAKEEVGLLREHKIQT-NRYT---VKVQRELELDELALRALKEDRKRFLCKAVENYINCLLS-GE-EH-D-MW-VF-RLCSLWLENSGV-------------------SEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIIL--ALANANRDEFLTKPEVA-RRSRITKNVPKQSSQL-DE----DR---TEAANRIICTIRS---R-----RPQMV-------R------------SVE-------------------ALCDAYII-------------------------------------LA----------------------------N------L--------------------DA------------------------------------TQ-WKTQ-----R-------------K-G--------------------I--N---I-----------PA---------------------------D---------------------------Q------PIT------------------K----L----------K-N-----LEDVVV-----P------T--MEIKVD--H---TGEY-------G---NLVTIQSFKAEFRLA-G-GVNLPKIIDCVGSDGKERRQLVKG--R--DDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNN--EDGAHKRYR--PNDFSAF-QCQK--KM-M-EVQ------KKSFEEKYEVFMDVCQ-NFQ-P--VFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVA-----------FE---------QG---K-I-LPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDET--ELHPTLNA-D--DQEC-KRNLSDIDQSFNKVAERVLMRLQEKLKGVE------E--GTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV
1 PsiBlast_PDB 72.60100% -33 - C1 - - 5NP0 - - ATM_HUMAN A:[13-3066] --LVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDR------------DAVFRFLQKYIQKETECLRIAK------------KKMQEISSLVKYFIKCANRRAPRLK-CQELLNYIMDTVKD--------------SNILLKDILSVRKYW---CEISQQQWLELFSVYFRLYLK-PSQDVHRVLVARIIHA---VTKGCCSQTDGLNSKFLDFFSKAIQCAR-QE-KSSSGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQ-H-RLNDSLKEVIIELFQLQ---IY------------------STKWRSILYNLYDLLVNEI----S---------H---------------------NIAVKE---------NLIELMADICHQVFN----------------------------------------------------------PWLQIATQLISK---------LSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQD--------QKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLV------EVDREFWK-LFTGSACR---PAVCCLTLALTTS-----VKMGIEQNMCEVN-RSF----SIMKWLLFYQLE-GDLE-----------NFPHLVLE----KILVSLTMKNCKAAMNFFQSVPECEH-HQKDKEELSFSEVEELFLQTTFDKMDFLT----------------FSVHQNLKESLDRCLL---GL-SEQL---LNNYSSEITNSETLVRCSRLLVGVLGCYCYMG--VIAEEEAYKSELFQKAKSLMQCAGESIT-------------------------------------------------------------------ASFIKKPFDRGEVE--S-M-EDDTNGNLMEVEDQSSMNLFNDY-------------SQSTIGAINPLAE-EYL--------------------------------AADIRRKLLMLIDS---------HLHMYLMLLKELPGEEY---PLPMEDVLELLKPLSNVCSLY--RR----CKTI-------LNHVLHVVKNLGQSNMDSENTRDAQGQFLTVIGAF--------KYIFSVRMALVNCLKTLLE-A-DPYSKWAILNVMGKDFPVNEVFTQFLADNHHQVRMLAAE------------SSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRKSVLLTLIAVVLSCSP-ICE-KQALFALC----------------VKKVLEKVSETFG-------MASHLDYLVLEWL------------------------------------------FILLNYTNIEDFYRSCYKVLIPHLVIRS---HFDEVKS-----IQEDWK--------SLLTDCFPKILVNILPYFAYEGTRDSGMAQQRETATK-----------------------------PEIVVELLMTLHEPA--NSSA----------------------LCDFS--GDLDPAP-P--PHFP-----SHVI--KAT-AYISNCHKTK---------KSPDSYQKILLAICEQAAE-T---NNVYKKHRILKIYHLFVSLLLKD-IKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQV----------ALEN----HLHVIVGTLIPLVYEQV---E--------VQKQVLDLLKYLVIDNKDNENLYI--TIKLLDPFP-----DHVVFKDL------RITQQKIKYSRG----L-EEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQM--VDIMR---------AS-----------QDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLF--E--DKELQWTFIMLTY-L-NNTLV-E-DCVKVRSAAVTCLKNILATK---------T----------------GH-S---FWEI-YKMTTDPMLAYLQP-----FRTS--------------------------PL-SENHDIWIKTLTCAFLDSGGT--KCEILQLLKPMCEVK-TDFCQTVLPYLIHDILLQ--DTN--E---SWRNLLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQKRPSS-------G-----T------------IFNDAFWLD-------LNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLA------------------EETGISLQDLLLEIYRSIGEPDSLYGCGGGKM--L-QP--I-TRL-R-TYEH-EAMWGKALVT----YDLETAIPS-----------S---T------RQA-----GIIQALQNLGLCHILSVYLKGLDY-ENKD-WCPELEELHYQAAWRNMQWDHCTSVS-------------------SYHESLYNALQSL-RD-------------STFYESLKYARVKEVEEMCKRSLE--S-VYSLYPTLSRLQAIGELESIGELFSR-----------T--HRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNS----Q--RECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSV-----SC-----------GVS---EWQLEEAQVFWAK-K-EQSLALSILKQMIKKLDAS--------CA----------PSLKLTYTECLRVCGNWLAETC----LENPAVIMQ--TYLEKAV-EVAGN-----SDELRNGKMKAFLSLARFSDTQYQ---------RIEN-----------YMKSSEFENKQ--ALLKRAKE--------------RYT---VKVQRELELDELALRALKEDRKRFLCKAVENYINCLLS-GE-EH-D-MW-VF-RLCSLWLENSGV-------------------SEVNGMMKRDGMKIPTYKFLPLMYQLAARMG----GGLGFHEVLNNLISRISMDHPHHTLFIIL--ALANANRDEF-------------------------DE----DR---TEAANRIICTIRS---R-----RPQMV-------R------------SVE-------------------ALCDAYII-------------------------------------LA----------------------------N------L--------------------D-------------------------------------------------R-------------K-G--------------------I--N---I-----------PA---------------------------D---------------------------Q------PIT------------------K----L----------K-N-----LEDVVV-----P------T--MEIKVD--H---TGEY-------G---NLVTIQSFKAEFRLA-G-GVNLPKIIDCVGSDGKERRQLVKG--R--DDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNN--EDGAHKRYR--PNDFSAF-QCQK--KM-M-------------FEEKYEVFMDVCQ-NFQ-P--VFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVA-----------FE---------QG---K-I-LPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDET--ELH--------------------IDQSFNKVAERVLMRLQEKLKGVE------E--GTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV
67 HHSearch 65.5895% -1 * C1 * - 6K9L - - ? A:[2-3054] -SLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDR------------DAVFRFLQKYIQKETECLRIAK------------KKMQEISSLVKYFIKCANRRAPRLK-CQELLNYIMDTVKD--------------SNILLKDILSVRKYW---CEISQQQWLELFSVYFRLYLK-PSQDVHRVLVARIIHA---VTKGCCSQTDGLNSKFLDFFSKAIQCAR-QE-KSSSGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQHRLN--DSLKE-VIIELFQL---QIY-----------------STKWRSILYNLYDLLVNEI----S---------H---------------------NIAVKE---------NLIELMADICHQVFN----------------------------------------------------------PWLQIATQLISK---------LSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLV------EVDREFWKLFTGSACR---PAVCCLTLALT-TS-----VKMGIEQNMCEVN-RSFSLKESIMKWLLF-YQLEGDLE---------------NFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHQKDKEE-LSFSEVEELFLQTTFDKMDFLT------------FSVHQNLKESLDRCLLGLSE---QLLNNYSSEITNSETLVRCSRL--LVGVLGCYCYMGVIAEEEA-YKSELFQKAKSLMQCAGES-------IT-------------------------------------------------------------------ASFIKKPFDRGEVESMEDDTNGNLMEVEDQS---SMNLFN-DY-------------SQSTIGAINPLAE-EYL--------------------------------AADIRRKLLMLIDS---------HLHMYLMLLKELPGEEY---PLPMEDVLELLKPLSNVCSLY--RR----CKTILNHVLHVVKNLGQSNMDSEN-------TRDAQGQFLTVIGAF--------KYIFSVRMALVNCLKTLLE-A-DPYSKWAILNVMGKDFPVNEVFTQFLADNHHQVRMLAAE------------SSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRKSVLLTLIAVVLSCSP-ICE-KQALFALC----------------VKKVLEKVSETFG-------MASHLDYLVLEWL------------------------------------------FILLNYTNIEDFYRSCYKVLIPHLVIRS---HFDEVKS-----IQEDWK--------SLLTDCFPKILVNILPYFAYEGTRDSGMAQQ----------------------------HLFISNLPEIVVELLMTLHEPA--NSSA----S----Q--------S-TDLCDFS--GDLDPAPNP--PHFP-----SHVI--KATFAYISNCHKTK-------LSKSPDSYQKILLAICEQAAE-T---NNVYKKHRILKIYHLFVSLLLKD-IKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQV----------ALEN----HLHVIVGTLIPLVYEQV---E--------VQKQVLDLLKYLVIDNKDNENLYI--TIKLLDPFP-----DHVVFKDL------RITQQKIKYSRG----L-EEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQM--VDIMR---------AS-----------QDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLF--E--DKELQWTFIMLTY-L-NNTLV-E-DCVKVRSAAVTCLKNILATK---------T----------------GH-S---FWEI-YKMTTDPMLAYLQP-----FRTS--------------------------PL-SENHDIWIKTLTCAFLDSGGT--KCEILQLLKPMCEVK-TDFCQTVLPYLIHDILLQ--DTN--E---SWRNLLSTHVQGFFTSCLR-FSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQKRPSS-------G-----T------------IFNDAFWLD-------LNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQE-----------------------EETGISLQDLLLEIYRSIGEPDSLYGCGGGKM--L-QP--I-TRL-R-TYEH-EAMWGKALVT----YDLETAIPS-----------S---T------RQA-----GIIQALQNLGLCHILSVYLKGLDY---------ELEELHYQAAWRNMQWDHCTSVS-------------------SYHESLYNALQSL-RD-----R-----EFSTFYESLKYARVKEVEEMCKRSLE--S-VYSLYPTLSRLQAIGELESIGELFSRS-----V----T--HRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNS----Q--RECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSV-----SC-----------GVS---EWQLEEAQVFWAK-K-EQSLALSILKQMIKKLDAS--------CA----------PSLKLTYTECLRVCGNWLAETC----LENPAVIMQ--TYLEKAV-EVA-------SDELRNGKMKAFLSLARFSDTQYQ---------RIEN-----------YMKSSEFENKQ--ALLKRAK---------------RYT---VKVQRELELDELALRALKEDRKRFLCKAVENYINCLLS-GE-EH-D-MW-VF-RLCSLWLENSGV-------------------SEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIIL--ALANANRDEF-----------------------L-DE----DR---TEAANRIICTIRS---R-----RPQMV-------R------------SVE-------------------ALCDAYII-------------------------------------LA----------------------------N------L--------------------DA------------------------------------TQ-WKTQ-----R-------------K-G--------------------I--N---I-----------PA---------------------------D---------------------------Q------PIT------------------K----L----------K-N-----LEDVVV-----P------T--MEIKVD--H---TGEY-------G---NLVTIQSFKAEFRLA-G-GVNLPKIIDCVGSDGKERRQLVKG--R--DDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNN--EDGAHKRYR--PNDFSAF-QCQK--KM-M-EVQ------K--FEEKYEVFMDVCQ-NFQ-P--VFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVA-----------FE---------QG---K-I-LPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDET--EL----------------------DQSFNKVAERVLMRLQEKLKGVE------E--GTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKA--
2 PsiBlast_PDB 58.25100% -36 - C1 - - 5NP1 - - ATM_HUMAN A:[13-3066] --LVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDR------------DAVFRFLQKYIQKETECLRIAK------------KKMQEISSLVKYFIKCANRRAPRLK-CQELLNYIMDTVKD--------------SNILLKDILSVRKYW---CEISQQQWLELFSVYFRLYLK-PSQDVHRVLVARIIHA---VTKGCCSQTDGLNSKFLDFFSKAIQCAR-QE-KSSSGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQ-H-RLNDSLKEVIIELFQLQ---IY------------------STKWRSILYNLYDLLVNEI----S---------H---------------------NIAVKE---------NLIELMADICHQVFN----------------------------------------------------------PWLQIATQLISK---------LSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQGSLV------EVDREFWK-LFTGSACR---PAVCCLTLALTTS-----VKMGIEQNMCEVN-RSFSLKESIMKWLLFYQLE-GDLE-----------NFPHLVLE----KILVSLTMKNCKAAMNFFQSVPECEH-HQKDKEELSFSEVEELFLQTTFDKMDFLT----------------FSVHQNLKESLDRCLL---GL-SEQL---LNNYSSEITNSETLVRCSRLLVGVLGCYCYMG--VIAEEEAYKSELFQKAKSLMQCAGESIT-------------------------------------------------------------------ASFIKKPFDRGEVE--S-M-EDDTNGNLMEVEDQSSMNLFNDY-------------SQSTIGAINPLAE-EYL--------------------------------AADIRRKLLMLIDS---------HLHMYLMLLKELPGEEY---PLPMEDVLELLKPLSNVCSLY--RR----CKTI-------LNHVLHVVKNLGQSNMDSENTRDAQGQFLTVIGAF--------KYIFSVRMALVNCLKTLLE-A-DPYSKWAILNVMGKDFPVNEVFTQFLADNHHQVRMLAAE------------SSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRKSVLLTLIAVVLSCSP-ICE-KQALFALC----------------VKKVLEKVSETFG-------MASHLDYLVLEWL------------------------------------------FILLNYTNIEDFYRSCYKVLIPHLVIRS---HFDEVKS-----IQEDWK--------SLLTDCFPKILVNILPYFAYEGTRDSGMAQQ----------------------------HLFISNLPEIVVELLMTLHEPA--NSSA----S----Q--------S-TDLCDFS--GDLDPAPNP--PHFP-----SHVI--KATFAYISNCHKTK-------LSKSPDSYQKILLAICEQAAE-T---NNVYKKHRILKIYHLFVSLLLKD-IKSGLGGAWAFVLRDVIYTLIHYINQRPSCIMDVSLRSFSLCCDLLSQV----------ALEN----HLHVIVGTLIPLVYEQV---E--------VQKQVLDLLKYLVIDNKDNENLYI--TIKLLDPFP-----DHVVFKDL------RITQQKIKYSRG----L-EEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQM--VDIMR---------AS-----------QDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLF--E--DKELQWTFIMLTY-L-NNTLV-E-DCVKVRSAAVTCLKNILATK---------T----------------GH-S---FWEI-YKMTTDPMLAYLQP-----FRTS--------------------------PL-SENHDIWIKTLTCAFLDSGGT--KCEILQLLKPMCEVK-TDFCQTVLPYLIHDILLQ--DTN--E---SWRNLLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLAVVDYMRRQKRPSS-------G-----T------------IFNDAFWLD-------LNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLA------------------EETGISLQDLLLEIYRSIGEPDSLYGCGG----------------------------------------------------------------------------------------CHILSVYLKGLDY---------ELEELHYQAAWRNMQWDHCTSVS-------------------SYHESLYNALQSL-RD-------------STFYESLKYARVKEVEEMCKRSLE--S-VYSLYPTLSRLQAIGELESIGELFSR-----------T--HRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNS----Q--RECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSV-----SC-----------GVS---EWQLEEAQVFWAK-K-EQSLALSILKQMIKKLDAS--------CA----------PSLKLTYTECLRVCGNWLAETC----LENPAVIMQ--TYLEKAV-EVAGN-----SDELRNGKMKAFLSLARFSDTQYQ---------RIEN-----------YMKSSEFENK-----------------------------------------ELALRALKEDRKRFLCKAVENYINCLLS-GE-EH-D-MW-VF-RLCSLWLENSGV-------------------SEVNGMMKRDGMKIPTYKFLPLMYQLAARMG----GGLGFHEVLNNLISRISMDHPHHTLFIIL--ALANANRDEF-------------------------DE----DR---TEAANRIICTIRS---R-----RPQMV-------R------------SVE-------------------ALCDAYII-------------------------------------LA----------------------------N------L--------------------D-------------------------------------------------R-------------K-G--------------------I--N---I-----------PA---------------------------D---------------------------Q------PIT------------------K----L----------K-N-----LEDVVV-----P------T--MEIKVD--H---TGEY-------G---NLVTIQSFKAEFRLA-G-GVNLPKIIDCVGSDGKERRQLVKG--R--DDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNN--EDGAHKRYR--PNDFSAF-QCQK--KM-M-------------FEEKYEVFMDVCQ-NFQ-P--VFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVA-----------FE---------QG---K-I-LPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYL---------------------------------IDQSFNKVAERVLMRLQEKLKGVE------E--GTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV
68 HHSearch 51.5420% -17 - C1 - - 6SL1 - - ? A:[14-2944] -------FKEIESHLV--SATARKDAVEALIAYF---------------------AYHRLFEALFRCTLIEKEAY------------AAAAARLERCPEALRLAVRHGVTT-IRRKTARAIIDHIVQVLP--------MPLLAGYVKV-LYEFLDNPASAENIAALSGEGWEVCVDFCIDVLSR-F----GTHVAVDVLSC---LYMLCIAHNAPIQRKADRLPHVVIQLLQLRQMKIGELQKMAFATFNIVFQRMQAEDVALCKTLVKQVVPLLSHWW------MLNSIRDEMLKTLYGT---RLYIQALLRE---ESF-PQDV---EELLDTLWCDYSRREE---RARLQLDDI-TFTNML-L----PPDHPRT--GIFSLRPHHTAGEQNWALLENLAILEAAYSKHG--------------------------------------NRVHQKL--HSLDPAVRLSALQLIPFLTRHKKPSLE--DVAETLEDLSKHVTAKQ-AIVASWAMLACSSLAIHEVSRH-------PSLSSSWKQLWQLAVRSLSLPPISRASCVLLNSILKANLIPRHELADDINQIVTTADISGPAILVDASLGLMLNLLRFRNN-------------MFPNASQATSNHIIRWVFVRWSP-AELTY-AS----LHG--THATPYDLV-NLLRACYGISPLVMAQ-PLRLFNGPIVLHWKEQ-AEMEPF-IRYLLLL-----------------AGSNASRRLALELFYPKVEELQELAESW------------SMERLRSM--VLACLTGALLLPDLVNINSSLSRDLESAVFSIVDATLKV--------------ILNS-PPSENLFGMILAS---SAPYI---P-HLIEPELIALKRERPHLLKFFGKLSEALYERSRR------------------------------------------------------------TLPRRDILLSYTPEAFYLETSLRIHFLDIIRLND--GEIGRIPEPIINQLAG------LSGEQFLC---CREFMREIFTSDA---IVPLGGATTILETAGHIVSRYEYACCEVALCNCIDI----MDSFINLWTDNH---------FDIAEMAGDLYHYLVKQSLPNNSMSAAAQIRLASLLLHLLE-V-KSEYAS-----NLGLPSSQSTLLKILQDGPMKLKHYIGLEIPKLFGLYVLK---------------THDDIFVDVLEHL-P--SDP-------DVVEGLAFRLFVLAELACRWP-TLL-RRSIYHTFEIPG----CVTHSALYAASCIKRIAQTLKLSGPQELFKLFAPQLLYTWLDN----D-----------------------------SIQDIAYEIFGFSSLLDLLREAQTEAAAIMMMRG---QEQEVCQ-LAQSLGLTPE--------KLVQQSFTKIIAYSIAHDISIA------------YVTGESRMR-----KILG--KEEYLANIHLNFADIISTFFDIFDQED--PIEKAFRRD----ERFAYAAETL-EEIKKLGHLPTALPPNQQ--PMFR-----AKYL--PREIVHLCSRTQYEPENI-----WTPALVVFVARKLLKTIHP-A---LGPLHACSVLRKIRVLICLAGDH-AIS------GYPLEMLLHSLRVFVVDP-------------ECADDALGITQYLIKRGDEYLKR----TPSFLAGYALSSLADLRVFLSSQESQFKATKSKAQEFHAWFS----------K--YLAAYDSPEFKDEGQKQAFRSI------TENAAHIRAS-GNAEKGTHESNLLLEILK-DW----GR-----ENQLLNEPARDVALSMLCG---------VFNIPPSSRLDVIETDEDAIKNGAVVWKSCSSQRL----G--GEYLAWAGRVLGRSFAASGEVPEDLLRESQ-LQE-YRRL--S--QGVGSSEEGLLNL-I-KSLTI-S-GDCFTAGLAEAALRTIVSDA---------I----------------SD-NDHDLLSA-CQE--SLPEPLLIASNWDPYRTPLSD-------------------EVFSAR-ALENPNWSQHLAIRLALSAP---KIVTLRVLPPILSKV-KGFAERAFPFVVHLVLAY--QLDKQQ---SAKRELSESLQEWLNFTS-------------------------EPAKENLKLLINTILYLRTQPLPGE-------S-----S------------IADRAHWLD-------VNMASAAAAATRCGMYKVALLFAELAAESTR-----------------------------------SDILLEIFENIDDPDAYYGLSQDAS--L-----S-TVL-A-RLEY-ENDGAKSLAFRGAQYDSHLRGRD-----------LQSRQ------DCN-----ALIKALSSLGLAGLSNSLLQSQ------------SLDATFTTARKLEIWNLPAPVN-----------------SDSWAVTVYKAYQSM-YQ-----AQ----ELDTVRSMVHDGLKNTVRHLSSGS-L--N-TSVLRQQLGALAALTELDDILNVRD---------------QSELQCTLATFEKRSKWMMSGRYADVSQILSCRETTLSMWSQRHNLRAAGL-T--SADARLVQIRGMLLSSDIFRFHRARQETLNLSTALSDLIPS-----CESLGLS------VDA---AIKMEAANALWDH-G-EMISSIRMLQAIDKDSSLK--------K-----------QSVPLSRSDLLSKIGYQVSVAR----LESPDAIQK--KYLEPAL-KELKGKIE------GREAGQVFHQFAVFCDEQLQ---------NPD--------------SLEDLARLQ--NLKKGKDEEVAQLK--------SHL---AKAKQWQELDQQELRRVEQTRSEFLKLCIENYLLSLAA-SD-EH-D-ND-AL-RFMALWLEKSEE-------------------EVANEVVKKWINKVPTRKFALLMNQLSSRLQDHN---TLFQKLLIDLVYRICVDHPYHGMYHIW--TGARTRVNKD---------------------DEV-AV----SR---QRATDKIAKALSKNN-K-----VSSIW-------P------------AID-------------------QTSRVYHA-------------------------------------LA----------------------------M------D--------------------RD------------------------------------PTRYKSG-------------------Q-K--------------------V--PIKNS-----------PVG--------------------------Q---------------------------N------FLS------------------T----M----------S-N------NPIPP-----P------T--LQIEVS--A---NLDY-------S---HVPMIHKFAPEMAIA-S-GVSAPKILTAIGTDGRKYKQLVKGG-N--DDLRQDAIMEQVFAAVSELLKLHRETRQRNLGIRTYKVLPLTSSSGLIEFVSNTIPLHEYLMP------AHERYY--PKDLKGS-QCRK--EI-A-NAQ------TKNTETRIAVYRRVTE-RFH-P--VMRYFFMEYFPDPDEWFQKRTNYTRTTAAISMLGHVLGLGDRHGHNILLDHKTGEVVHIDLGVA-----------FE---------MG---R-V-LPV-PELVPFRLTRDIVDGMGITKTEGVFRRCCEFTLDALREEAASIQTILDSLRHDTLYQWSISPVRMAKLQN-------------------------------------SEADRAIEVVKKKL-------------SKTLSVMATVNDLINQATSVSNLAVLYSGWAAYA
4 PsiBlast_PDB 40.8929% 16 - C1 - - 6SKZ - - ? A:[1774-2944] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AP--KIVTLRVLPPILSKV-KGFAERAFPFVVHLVLAYQLDKQ--Q---SAKRELSESLQEWL-----------------NFTSEPA--------KENLKLLINTILYLRTQPLPGE-------S-----S------------IADRAHWLD-------VNMASAAAAATRCGMYKVALLFAELAAESTR-----------------S------------------DILLEIFENIDDPDAYYGLSQDAS--L-ST--V-LAR-L-EYEN-DGAKSLAFRG----AQYDSHLRG-----------R---D------LQSRQDCNALIKALSSLGLAGLSNSLLQS--Q-QSID-GSSDSLDATFTTARKLEIWN----LPAP-----V--------NSDSWAVTVYKAYQSMYQA-----Q-----ELDTVRSMVHDGLKNTVRHLSSGSLN--T-SV-LRQQLGALAALTELDDILNVRDQS---------------ELQCTLATFEKRSKWMMSGRYADVSQILSCRETTLSMWSQRHNLRA----A--GLTSADARLVQIRGMLLSSDIFRFHRARQETLNLSTALSDLIPSCESL-----------GLSVDAAIKMEAANALWDH-G-EMISSI----RMLQAIDKD--------SS-L------KKQSVPLSRSDLLSKIGYQVSVAR----LESPDAIQK--KYLEPALKELKGKIEGREAGQV-------FHQFAVFCDEQLQNPDSLEDLARLQN-----------LKKGKDEEVAQLK-------------------------HL-AKAKQWQELDQQELRRVEQTRSEFLKLCIENYLLSLAA-SD-EH-D-ND-AL-RFMALWLEKSEE-------------------EVANEVVKKWINKVPTRKFALLMNQLSSRLQDH---NTLFQKLLIDLVYRICVDHPYHGMYHIWTGAR-------------VAVSRQRATDKIAKALSK-----------------NNKVSSIWP---A-----IDQTS-------R------------VYH-------------------ALA-------------------------------------------M----------------------------D------R--------------------DP------------------------------------TR-YKSG-----Q-------------K-V--------------------PIKN---S-----------PV---------------------------G---------------------------Q------NFL------------------S----T----------M-S-----NNPIPP-----P------T--LQIEVS--A---NLDY-------S---HVPMIHKFAPEMAIA-S-GVSAPKILTAIGTDGRKYKQLVKGG-N--DDLRQDAIMEQVFAAVSELLKLHRETRQRNLGIRTYKVLPLTSSSGLIEFVSNTIPLHEYLMP------AHERYY--PKDLKGS-QCRK--EI-A-NAQ------TKNTETRIAVYRRVTE-RFH-P--VMRYFFMEYFPDPDEWFQKRTNYTRTTAAISMLGHVLGLGDRHGHNILLDHKTGEVVHIDLGVA-----------FE---------MG---R-V-LPV-PELVPFRLTRDIVDGMGITKTEGVFRRCCEFTLDALREEAASIQTILDSLRHDTLYQWSISPVRMAKLQN-------------------------------------SEADRAIEVVKKKL-------------SKTLSVMATVNDLINQATSVSNLAVLYSGWAAYA
5 PsiBlast_PDB 40.7029% 16 - C1 - - 6SL0 - - ? A:[1774-2944] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AP--KIVTLRVLPPILSKV-KGFAERAFPFVVHLVLAYQLDKQ--Q---SAKRELSESLQEWL-----------------NFTSEPA--------KENLKLLINTILYLRTQPLPGE-------S-----S------------IADRAHWLD-------VNMASAAAAATRCGMYKVALLFAELAAESTR-----------------S------------------DILLEIFENIDDPDAYYGLSQDAS--L-ST--V-LAR-L-EYEN-DGAKSLAFRG----AQYDSHLRG-----------R---D------LQSRQDCNALIKALSSLGLAGLSNSLLQS--Q-QSID-GSSDSLDATFTTARKLEIWN----LPAP-----V--------NSDSWAVTVYKAYQSMYQA-----Q-----ELDTVRSMVHDGLKNTVRHLSSGSLN--T-SV-LRQQLGALAALTELDDILNVRDQS---------------ELQCTLATFEKRSKWMMSGRYADVSQILSCRETTLSMWSQRHNLRA----A--GLTSADARLVQIRGMLLSSDIFRFHRARQETLNLSTALSDLIPSCESL-----------GLSVDAAIKMEAANALWDH-G-EMISSI----RMLQAIDKD--------SS-L------KKQSVPLSRSDLLSKIGYQVSVAR----LESPDAIQK--KYLEPALKELKGKIEGREAGQV-------FHQFAVFCDEQLQNPDSLEDLARLQN-----------LKKGKDEEVAQLK-------------------------HL-AKAKQWQELDQQELRRVEQTRSEFLKLCIENYLLSLAA-SD-EH-D-ND-AL-RFMALWLEKSEE-------------------EVANEVVKKWINKVPTRKFALLMNQLSSRLQDH---NTLFQKLLIDLVYRICVDHPYHGMYHIWTGAR-------------VAVSRQRATDKIAKALSK-----------------NNKVSSIWP---A-----IDQTS-------R------------VYH-------------------ALA-------------------------------------------M----------------------------D------R--------------------DP------------------------------------TR-YKSG-----Q-------------K-V--------------------PIKN---S-----------PV---------------------------G---------------------------Q------NFL------------------S----T----------M-S-----NNPIPP-----P------T--LQIEVS--A---NLDY-------S---HVPMIHKFAPEMAIA-S-GVSAPKILTAIGTDGRKYKQLVKGG-N--DDLRQDAIMEQVFAAVSELLKLHRETRQRNLGIRTYKVLPLTSSSGLIEFVSNTIPLHEYLMP------AHERYY--PKDLKGS-QCRK--EI-A-NAQ------TKNTETRIAVYRRVTE-RFH-P--VMRYFFMEYFPDPDEWFQKRTNYTRTTAAISMLGHVLGLGDRHGHNILLDHKTGEVVHIDLGVA-----------FE---------MG---R-V-LPV-PELVPFRLTRDIVDGMGITKTEGVFRRCCEFTLDALREEAASIQTILDSLRHDTLYQWSISPVRMAKLQN-------------------------------------SEADRAIEVVKKKL-------------SKTLSVMATVNDLINQATSVSNLAVLYSGWAAYA
69 HHSearch 35.5117% -9 - C1 - - 6JXC - - ATM_YEAST A:[6-2787] -------IVETLNFLSSTKIKERNNALDELTTIL------------------PTKALSTTA---VELLASEHTKYCDLLR------LSLSENRLSTISYVLRLFVEKSCER--------LLLAVVPELMVKDGSK--------------------------------------LVDKICEYFQSQMKLSMV----TNFISILLNLLALDTVGIFQVTRTITWTVIDFLRLSK--------NTRLIMSLINQLILKCHCFSVIDTLMLIKEAWSYNLTIGCT-S-N--ELVQDQLSLFDVMSSELMNHKL--PYMIGQENYVE-------------YREYILLRLSNYKPQLFTVNHVEFS-YIRGSRDKN-SWFA----------W--------LKILGITKSLLTYFALNRKNE--------------NYSLLFKRRKCDSDIPSIL--TFLIHLLEENS-----------------------------SFAEQLKELLF------------------------------------NGDMARLFKVCLP----------SCLLLANSIK----SDEKTINQIYDLYELS---------NESFMLWGYLQY-----------------------ISSADRIFEWLKSKWN-------------------QFCNFI----SWLGN--------------WDESHKIWQHF-------QEQ-RE--------------------------LDLTRYNEILYRLLENI-------------------------------NLCGDSTFSE------------FIAAYKRTTLIT----------------------------------------IRT---I-NVDHLVLDKIN--------MKEIVNDFIRMQKNKS------QTG---------------------------------------------------------------STIDKAVR---AYL--------------------------------------------------LKQAIGEKSSYNKILEEFTEVLGEKLLCNHYSSSNQAMLLLTSY----IEA----------------------SDCNDILDWIISRFEDNSFTGVAPTVNLSMLLLSLLQNH-DLSHGS----IRGGKQRVFATFIKCLQKLDSSNIINIMNSISSYMAQVSYK---------------NQSIIFYEIKSLF-G--PPQ-------QSIEKSAFYSLAMSMLSLVSY-PSL-VFSLEDMMTYSG--FN---HTRAFIQQALNKITVAFRYQNLTELFEYCKFDLIMYWF---------------------------------------------------HEFLGRYFVEISAIYFSQGF--NQKWILDMLHAITGNGDA--------YLVDNSYYLCIPLAFISGGVNE----L----------IFDILPQISGKTTVKYHKK-YRLLMLKWI--IRFTDLGSLTELRS-TVEK----LFPTSY--------LSPYLFENS--SVSM-RYQY--PLHI-----PLAL--GATL--VQTQF--A-HEK-----NNTHEFKLLFLSVITDLEK-T---STYIGKLRCARELKYLFVLYENV-LVK------SSTLNFIIIRLSKFLIDT-------------QIHDEVITIFSSLLNLADKNTFEIEPSLPNLFCKIFIY-LRENK---QLSPSFQ--QAIKLLEHRDLIK----------I--KTWKYCLD--------AIFGNI------VQD------------DI-YENTELLD-AS-DCGVD---------DVVL------V--SLLFSYARRPVASKIG-----------CSLSKAAAINILKHHVPKEY-L----S--KNFKLWFAALSRRILQQE----------HLKNFEMVFRH--P--EQPHMIYQRISTF---NKEAE-LYDSTEVFFISECILTYLVGYS---------I----------------GNSESEFCFRDNIMN--EN-KDKVAP-----LDKDVLNAIY-PLAN-NFGMESFIC-DTYLSV-NEPYNCWLSKFARSLIHQISF--NIPPIVCLYPLCKGS-TAFCELVLTDLFFLSTTY--DP---K---SCLNWSNRIFTQIAMLLH------------------------VKDSEIKLKMLFNVIKMIRMGSRCKE-------R-----N------------CL--RIYSS-------LDLQEICQISLKIKEFKFGYLLFEEMNMPNIRE-------------------------------MNINTLQKIYECINDGDFLAGLPVPHS--I-----E-GVL-N-SINRIDSDTWKRFLFNNADFDANYTTSL-----------E---E------EKE-----SLIKATEDSGFYGLTSLL-ESR---L-S-----G-SSDVYKWNLELGDWKLLTPKVV-----------------DSKAKGLYYAIKNL-PQ-----D-----V-GFAEKSLEKSLLTIFDSRQ-------H-FISQTEWMDTLNAIIEFIKIAAIPQDV-----T----SF-PQTLMSIM-KADK--ERLNTIDFYDHKTTLKSRHTLMNVLSRNSLDENVK--C--SKYLRLGSIIQLANYVQLAIANGAPQDALRNATLMSKTVKN-----IAKLYDDPSVVSQIEK---LASFTSANALWES-R-EYKAPVMIMRDLLAQNEKN--------IS-ESILYDDFKLLINVPMDQIKARLVKWSSESR----LEPAAAIYE--KIIVNWD-INV---------EDHESCSDVFYTLGSFLDEQAQ---------KLR--------------SNGEIEDRE--HRSYTGKSTLKALELIYK--AKRHY---NRVLLQYNRDSEVLKALLLQKEKFLWHALHFYLNTLVF-SN-RY-D-NDIID-KFCGLWFENDDN-------------------SKINQLLYKEIGTIPSWKFLPWVNQIASKISMEE---NEFQKPLQLTMKRLLYKLPYDSLYSVM--SILLYEKQSNK--------------------DTN-IS----QK---IQAVKKILLELQG---YDRGAFAKKYL-------L------------PVQ-------------------EFCEMSVE-------------------------------------LA----------------------------N------L--------------------KF------------------------------------VQ-NTKT-----L-------------R-L--------------------A--N---L-----------KIG--------------------------Q---------------------------Y------WLK------------------Q----L----------N-M------EKLPL-----P------T--SNFTVKSSA---DGRK-------A----RPYIVSVNETVGITTT-GLSLPKIVTFNISDGTTQKALMKGS-N--DDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSK------LHTN-----DKITFD-QARK--GM-K-AVQ------TKSNEERLKAYLKITN-EIK-P--QLRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIA-----------FD---------QG---K-L-LPI-PELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSWVMSPVKKYEHLFE---------------------------------NENQESYRALKGVEEKLMG------------NGLSVESSVQDLIQQATDPSNLSVIYMGWSPFY
81 HHSearch 34.0222% 9 - C1 - - 4JSV - - MTOR_HUMAN A:[10-1174] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERAAKCRAYAKALHYKELEFQKGPT-------------------------------PAILESLISINNKLQQPEAAAGVLEYAMK-H-FGELE-IQA-T-WYEK-LHEWEDALVA----YDKKMDTNK-----------DDP-E------LML-----GRMRCLEALGEWGQLHQQCCEKWTLVNDE-TQAKMARMAAAAAWGLGQWDSMEEYTCM-----I--------PRDTHDGAFYRAVLAL-HQ-----D-----LFSLAQQCIDKARDLLDAELTAMAGE--S-YSRAYGAMVSCHMLSELEEVIQYKLVP--------------ERREIIRQIWWERLQGC-QRIVEDWQKILMVRSLVVSPH---------------------EDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPS-----RQLDHPLPT----VHP---QVTYAYMKNMWKS-A-RKIDAFQHMQHFVQTMQQQAQHAIATEDQ-Q------HKQELHKLMARCFLKLGEWQLNLQ----GINESTIPKVLQYYSAAT-EH------------DRSWYKAWHAWAVMNFEAVL---------HYKH-----------QNQARD--EK-----------------------------------------KKVTEDLSKTLLMYTVPAVQGFFRSISL-SR-GN-NLQD-TL-RVLTLWFDYGHW-------------------PDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPR---PLVGRLIHQLLTDIGRYHPQALIYPLT--VASKSTT-----------------------------T----AR---HNAANKILKNMCE---H-----SNTLV-------Q------------QAM-------------------MVSEELIR-------------------------------------VA----------------------------I------L--------------------WH------------------------------------EM-WHEGLEEASRLYFGERNVK----G-M--------------------F--E---VLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKS---------------------------G------NVKDLTQAWDLYYHVFRRISKQ----L----------P-QLTSLELQYVSPKLLMCR------D--LELAVP-------GTY-------DPNQPIIRIQSIAPSLQVI-T-SKQRPRKLTLMGSNGHEFVFLLKG--H--EDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRD------YREKK----KILLNI-EHRIMLRMAP-DYD------HLTLMQKVEVFEHAVN-NTA-GD-DLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDC-----------FE---------VA---M-TREKF-PEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNT---------------------------------------ALNKKAIQIINRVRDKLTGRD------FSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
71 HHSearch 33.5517% -8 - C1 - - 5X6O - - ATR_YEAST C:[535-2367] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSESLLSGILFSLHRIFS-HFQPPK---------QINKSFKLVQKCFMNSNRYLRLLSTRIIPLFNISDSHNS-----------EDEHTA----TLIKFL----QSQ-------KLPVVKENLVIAWTQLTLTTS-NDVFDTLLLKLIDIFNSDDY---SLRIMMTLQIKNMAKILKKTPY-QLLSPILPVLLRQLGKNLVERK----------------------------VGFQNL-IELLGYS-SKTILDIFQRYIIPYAIIQY---KSDVLSE-IAKIMCDG-TSLINQMKVNLLKKNSRQIFAVALVKHGLFSL---------DILETLFLNR-A-----------Y-ITAYLPD--Y-TLAEITKLYKNS-SDSENA----N----M--------I-LCSLRFL--ITNFEKDKRHGSKYKNINWTDDQE--QAFQKKLQDN-------ILGIFQ-----------VFSSDIHD-VEGRTTYYEKLRVINGISFLIIYAPKK-S-------IISALAQISICLQTGLGL---------KEVRYEAFRCWHLLVRHL---NDEELST----VIDSLIAFILQKWSEFNG--K--------LRNIVYSILDTLIKEKSD--LILKLKPYTTLA-LV-----GKPELGILARDGQFARMVNKIR---S---TT-DLIPIFANNLK-SSNKYVINQNLDDIEVYLRRKQTER--SIDF------------------------------DITLVLGALLDTSHKFR--NLDKDLCEKCAKCISMIGVLDVTKHEFKRTTYSE--NEVYDL--NDSVQTIKFLIWVINDILVPAFWQ-S-ENPSKQLFVALVIQESLKYC---------GLSSESWDMNHKELYPNEA-K---LWEK-FN---SVSKTTIYP-----LLSSLYLAQSWKE----Y--VPLKY-PSNNF---EGYKIWVKRFTLDLLKTGTT--ENHPLHVFSSLIR---GSLSNFLLPYISLDIIIK--A-----PYADILNGIIIEFDSIFTCNLEGM-----------------NNLQVDSLRMCYESIFRVFEYCKKWATEFKQNYSKLHGTFIIKD------------TKTTNMLLRIDEFLRTTPSDLLAQRSLETDSFERSALYLEQCYRQNPHDK-------------------------N-QNGQLLKNLQITYEEIGDIDSLDGVLRTFAT-G-NL--V-SKI-E-ELQY-SENWKLAQDC----FNVLGKF--D----------P---K------TTT-----RMLKSMYDHQLYSQIISNSSF----------VKEWYSIGLEAANLEGNVQTLKNWVEQ-----IESLRNIDDREVLLQYNIAKALIAI-SN-----E-----DPLRTQKYIHNSFRLIGTNFITSSKE--TTLLKKQNLLMKLHSLYDLSFLSSAKDK---------------FEYKSNTTILDYRMERI-GADFVPNHYILSMRKSFDQLKMNE--------------QADADLGKTFFTLAQLARNNARLDIASESLMHCLERRLP------------------------QAELEFAEILWKQ-G-ENDRALKIVQEIHEKYQEN--------S-----------SVNARDRAAVLLKFTEWLDLSN----NSASEQIIK--QYQD-IF-QI------------DSKWDKPYYSIGLYYSRLLE---------RK---------------------------------------------------------------------------GRFEYRAISYFLLAFEK-NT-AKVR-EN-LP-KVITFWLDIAAASISENRKEMLSKAT-----EDICSHVEEALQH-PTYIWYFVLTQLLSRLL---------AQIIMHILLSLAVEYPSHILWYIT--ALVNSN-----------------------------SS----KR---VL---HILEKYRQHSQN-----PHDLV-------S------------SAL------------------------LTR-------------------------------------VC----------------------------L------Q--------------------DV------------------------------------KS-ITSR-------------------S-G--------------------K--S---L-----------E---------------------------------------------------------NVAPSAMVV------------------P----V----------R-K-----NLDIIS-----P------L--ESN-----S-------PF-----R---PVVSIIRFGSSYKVF-S-SLKKPKQLNIIGSDGNIYGIMCK---K--EDVRQDNQYMQFATTMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILST------KYESLK-----IKY--SLKS--LH-D-RWQ------HTAVDGKLEFYMEQVD-KFP-P--ILYQWFLENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCL-----------FE---------KG---K------------FRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYDRNMDHSI--------------------------------------------------QKALKVLRNKIRGIDPQ----D--GLVLSVAGQTETLIQEATSEDNLSKMYIGWLPF-
82 HHSearch 32.4822% 21 - C1 - - 5WBY - - B:[13-1177] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERAAKCRAYAKALHYKELEFQKGPT-------------------------------PAILESLISINNKLQQPEAAAGVLEYAM--KHFGELE-IQA-T-WYEK-LHEWEDALVA----YDKKMDTNK-----------DDP-E------LML-----GRMRCLEALGEWGQLHQQCCEKWTLVNDE-TQAKMARMAAAAAWGLGQWDSMEEYTCM-----I--------PRDTHDGAFYRAVLAL-HQ-----D-----LFSLAQQCIDKARDLLDAELTAMAGE--S-YSRAYGAMVSCHMLSELEEVIQYKLVP--------------ERREIIRQIWWERLQGC-QRIVEDWQKILMVRSLVVSPH---------------------EDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPS-----RQLDHPLPT----VHP---QVTYAYMKNMWKS-A-RKIDAFQHMQHFVQTMQQQAQHAIATEDQ-Q------HKQELHKLMARCFLKLGEWQLNLQ----GINESTIPKVLQYYSAAT-EH------------DRSWYKAWHAWAVMNFEAVL---------HYKH-----------QNQARD--EK-----------------------------------------KKVTEDLSKTLLMYTVPAVQGFFRSISL-SR-GN-NLQD-TL-RVLTLWFDYGHW-------------------PDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPR---PLVGRLIHQLLTDIGRYHPQALIYPLT--VASKST-----------------------------TT----AR---HNAANKILKNMCE---H-----SNTLV-------Q------------QAM-------------------MVSEELIR-------------------------------------VA----------------------------I------L--------------------WH------------------------------------EM-WHEGL----EEASRLYFGERNVKG-M--------------------F--E---VLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKS---------------------------G------NVKDLTQAWDLYYHVFRRISKQ----L----------P-QLTSLELQYVS------PKLLMCRD--LELAV-------PGTY-------DPNQPIIRIQSIAPSLQVI-T-SKQRPRKLTLMGSNGHEFVFLLKG--H--EDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRD------YREKK----KILLNI-EHRIMLRM-APDYD------HLTLMQKVEVFEHAVN-NTAGD--DLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDC-----------FE---------VA---M-TREKF-PEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNT---------------------------------------ALNKKAIQIINRVRDKLTGRD------FSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
72 HHSearch 32.4721% -1 - C1 - - 5YZ0 - - ATR_HUMAN A:[774-2644] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IPSPVKLAFIDNLHHLCK-H-LDFRE-----DETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSE------------DGFIKELFVLRMKEAY-T---H----AQISRNNELKDTLILTTGDIGRAAKGDLV-PFALLHLLHCLLSKSA---SVSGAAYTEIRALVAAKSVKLQ-SFFSQYKKPICQFLVESL-HSSQMTALPNTPCQNADVRKQDVAHQREMALNTLSEI-ANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRT-LGKQLNVNRR--------EILINNFKYIFSHLVCSCSKD------------ELERALHYLK-----NETE--IE-LGSLL---------------------------------------------------A--SSDDP------YQGP-----RDIISPELMADYLQPK-------LLGIL-----------AFFNMQLLSSS---VGIEDKKMALNSLMSLMKLMGPKHV--------SSVRVKMMTTLRTGLRFK--------DDFPELC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVTG--VEDSSFAYGLLME-LTRAYLAYA-DNSRAQDSAAYAIQELLSIYDCREMETNGP----------------GH-Q---LWRR-FP---EHVREILEP-----HLNTRYKSSQKST---DW--SGVK-KPIYLSKLGSNFAEWSASWAGYLITKVRHDLASKIFTCCSIMMKHD-FKVTIYLLPHILVYVLLG--CNQ------EDQQEVYAEIMAVLKHDD-------------------------DLCQLSTQTVFSMLDHLTQWARHKFQALKAE-K------DSMVSTVDYEDYQSVTRFLDL-------IPQDTLAVASFRSKAYTRAVMHFESFITEKKQNI-----------------------------QEHLGFLQKLYAAMHEPDGVAGVSAIRKAEP-SL--K-EQI-L-EHES-LGLLRDATAC----YDRAIQLEP-----------DQI-I------HYH-----GVVKSMLGLGQLSTVITQVNGVHA-NRSE-WTDELNTYRVEAAWKLSQWDLVENYLAA-----DG-------KSTTWSVRLGQLLLSA-KK-----R-----DITAFYDSLKLVRAEQIVPLSAASFERGS-YQRGYEYIVRLHMLCELEHSIKPLFQ-------------------------VARLEMT-QNSYRAKEPILALRRALLSLNKRPD--------------YNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRL---------------------A---ELYVERAKWLWSK-G-DVHQALIVLQKGVELCFPE--------NE-TP-----PEGKNMLIHGRAMLLVGRFMEETA----NFESNAIMK--KYKD-VT-AC------------LPEWEDGHFYLAKYYDKLMP---------MVTD---------------NK----------------------------------------------------MEKQGDLIRYIVLHFGRSLQY-GN-QF-IYQS-MP-RMLTLWLDYGTKAYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSH---DEVFVVLMEIIAKVFLAYPQQAMWMMT--AVSKSS-----------------------------YP----MR---VNRCKEILNKAIHMKKS-----LEKFV-------G------------DAT-------------------RLTDKLLE-------------------------------------LC----------------------------N------K--------------------PV------------------------------------DG-----------------------------------------------------------------------------------------------H---------------------------FK-----MLK------------------K----LVEEATFSEILI-P-----LQSVMI-----P------T--LPSILG--THANHASHE-----------WAYIAGFDDMVEIL-A-SLQKPKKISLKGSDGKFYIMMCKP--K--DDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTK------LYKEK---GVYMTGK-ELRQ--CM-L-P-K------SAALSEKLKVFREFLLPRHP-P--IFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCL-----------FN---------KG---E-T-FEV-PEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSK---------L-----------------------------NETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVT--GLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM
80 HHSearch 32.2522% 19 - C1 - - 4JSP - - MTOR_HUMAN A:[10-1174] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERAAKCRAYAKALHYKELEFQKGPT-------------------------------PAILESLISINNKLQQPEAAAGVLEYAMK-H-FGELE-IQA-T-WYEK-LHEWEDALVA----YDKKMDTNK-----------DDP-E------LML-----GRMRCLEALGEWGQLHQQCCEKWTLVNDE-TQAKMARMAAAAAWGLGQWDSMEEYTCM-----I--------PRDTHDGAFYRAVLAL-HQ-----D-----LFSLAQQCIDKARDLLDAELTAMAGE--S-YSRAYGAMVSCHMLSELEEVIQYKLVP--------------ERREIIRQIWWERLQGC-QRIVEDWQKILMVRSLVVSPH---------------------EDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPS-----RQLDHPLPT----VHP---QVTYAYMKNMWKS-A-RKIDAFQHMQHFVQTMQQQAQHAIATEDQ-Q------HKQELHKLMARCFLKLGEWQLNLQ----GINESTIPKVLQYYSAAT-EH------------DRSWYKAWHAWAVMNFEAVL---------HYKH-----------QNQARD--EK-----------------------------------------KKVTEDLSKTLLMYTVPAVQGFFRSISL-SR-GN-NLQD-TL-RVLTLWFDYGHW-------------------PDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPR---PLVGRLIHQLLTDIGRYHPQALIYPLT--VASKSTT-----------------------------T----AR---HNAANKILKNMCE---H-----SNTLV-------Q------------QAM-------------------MVSEELIR-------------------------------------VA----------------------------I------L--------------------WH------------------------------------EM-WHEGLEEASRLYFGERNVK----G-M--------------------F--E---VLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKS---------------------------G------NVKDLTQAWDLYYHVFRRISKQ----L----------P-QLTSLELQYVS------PKLLMCRD--LELAV-------PGTY-------DPNQPIIRIQSIAPSLQVI-T-SKQRPRKLTLMGSNGHEFVFLLKG--H--EDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRD------YREKK----KILLNI-EHRIMLRMAP-DYD------HLTLMQKVEVFEHAVN-NTAGD--DLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDC-----------FE---------VA---M-TREKF-PEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNT---------------------------------------ALNKKAIQIINRVRDKLTGRD------FSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
6 PsiBlast_PDB 31.5629% 10 - C1 - - 6SL1 - - ? A:[1774-2944] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AP--KIVTLRVLPPILSKV-KGFAERAFPFVVHLVLAYQLDKQ--Q---SAKRELSESLQEWL-----------------NFTSEPA--------KENLKLLINTILYLRTQPLPGE-------S-----S------------IADRAHWLD-------VNMASAAAAATRCGMYKVALLFAELAAESTR-----------------S------------------DILLEIFENIDDPDAYYGLSQDAS--L-ST--V-LAR-L-EYEN-DGAKSLAFRG----AQYDSHLRG-----------R---D------LQSRQDCNALIKALSSLGLAGLSNSLLQS--Q----------SLDATFTTARKLEIWN----LPAP-----V--------NSDSWAVTVYKAYQSMYQA-----Q-----ELDTVRSMVHDGLKNTVRHLSSGSLN--T-SV-LRQQLGALAALTELDDILNVRDQS---------------ELQCTLATFEKRSKWMMSGRYADVSQILSCRETTLSMWSQRHNLRA----A--GLTSADARLVQIRGMLLSSDIFRFHRARQETLNLSTALSDLIPSCESL-----------GLSVDAAIKMEAANALWDH-G-EMISSI----RMLQAIDKD--------SS-L------KKQSVPLSRSDLLSKIGYQVSVAR----LESPDAIQK--KYLEPALKELKGKIEGREAGQV-------FHQFAVFCDEQLQNPDSLEDLARLQN-----------LKKGKDEEVAQLK-------------------------SHLAKAKQWQELDQQELRRVEQTRSEFLKLCIENYLLSLAA-SD-EH-D-ND-AL-RFMALWLEKSEE-------------------EVANEVVKKWINKVPTRKFALLMNQLSSRLQDH---NTLFQKLLIDLVYRICVDHPYHGMYHIWTGARTRVNKDD-----EVAVSRQRATDKIAKALSK-----------------NNKVSSIWP---A-----IDQTS-------R------------VYH-------------------ALA-------------------------------------------M----------------------------D------R--------------------DP------------------------------------TR-YKSG-----Q-------------K-V--------------------PIKN---S-----------PV---------------------------G---------------------------Q------NFL------------------S----T----------M-S-----NNPIPP-----P------T--LQIEVS--A---NLDY-------S---HVPMIHKFAPEMAIA-S-GVSAPKILTAIGTDGRKYKQLVKGG-N--DDLRQDAIMEQVFAAVSELLKLHRETRQRNLGIRTYKVLPLTSSSGLIEFVSNTIPLHEYLMP------AHERYY--PKDLKGS-QCRK--EI-A-NAQ------TKNTETRIAVYRRVTE-RFH-P--VMRYFFMEYFPDPDEWFQKRTNYTRTTAAISMLGHVLGLGDRHGHNILLDHKTGEVVHIDLGVA-----------FE---------MG---R-V-LPV-PELVPFRLTRDIVDGMGITKTEGVFRRCCEFTLDALREEAASIQTILDSLRHDTLYQWSISPVRMAKLQN-------------------------------------SEADRAIEVVKKKL-------------SKTLSVMATVNDLINQATSVSNLAVLYSGWAAYA
3 PsiBlast_PDB 31.1029% 12 - C1 - - 6SKY - - ? A:[1774-2944] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AP--KIVTLRVLPPILSKV-KGFAERAFPFVVHLVLAYQLDKQ--Q---SAKRELSESLQEWL-----------------NFTSEPA--------KENLKLLINTILYLRTQPLPGE-------S-----S------------IADRAHWLD-------VNMASAAAAATRCGMYKVALLFAELAAESTR-----------------S------------------DILLEIFENIDDPDAYYGLSQDAS--L-ST--V-LAR-L-EYEN-DGAKSLAFRG----AQYDSHLRG-----------R---D------LQSRQDCNALIKALSSLGLAGLSNSLLQS--Q----------SLDATFTTARKLEIWN----LPAP-----V--------NSDSWAVTVYKAYQSMYQA-----Q-----ELDTVRSMVHDGLKNTVRHLSSGSLN--T-SV-LRQQLGALAALTELDDILNVRDQS---------------ELQCTLATFEKRSKWMMSGRYADVSQILSCRETTLSMWSQRHNLRA----A--GLTSADARLVQIRGMLLSSDIFRFHRARQETLNLSTALSDLIPSCESL-----------GLSVDAAIKMEAANALWDH-G-EMISSI----RMLQAIDKD--------SS-L------KKQSVPLSRSDLLSKIGYQVSVAR----LESPDAIQK--KYLEPALKELKGKIEGREAGQV-------FHQFAVFCDEQLQNPDSLEDLARLQN-----------LKKGKDEEVAQLK-------------------------SHLAKAKQWQELDQQELRRVEQTRSEFLKLCIENYLLSLAA-SD-EH-D-ND-AL-RFMALWLEKSEE-------------------EVANEVVKKWINKVPTRKFALLMNQLSSRLQDH---NTLFQKLLIDLVYRICVDHPYHGMYHIWTGAR-------------VAVSRQRATDKIAKALSK-----------------NNKVSSIWP---A-----IDQTS-------R------------VYH-------------------ALA-------------------------------------------M----------------------------D------R--------------------DP------------------------------------TR-YKSG-----Q-------------K-V--------------------PIKN---S-----------PV---------------------------G---------------------------Q------NFL------------------S----T----------M-S-----NNPIPP-----P------T--LQIEVS--A---NLDY-------S---HVPMIHKFAPEMAIA-S-GVSAPKILTAIGTDGRKYKQLVKGG-N--DDLRQDAIMEQVFAAVSELLKLHRETRQRNLGIRTYKVLPLTSSSGLIEFVSNTIPLHEYLMP------AHERYY--PKDLKGS-QCRK--EI-A-NAQ------TKNTETRIAVYRRVTE-RFH-P--VMRYFFMEYFPDPDEWFQKRTNYTRTTAAISMLGHVLGLGDRHGHNILLDHKTGEVVHIDLGVA-----------FE---------MG---R-V-LPV-PELVPFRLTRDIVDGMGITKTEGVFRRCCEFTLDALREEAASIQTILDSLRHDTLYQWSISPVRMAKLQN-------------------------------------SEADRAIEVVKKKL-------------SKTLSVMATVNDLINQATSVSNLAVLYSGWAAYA
83 HHSearch 30.7715% -17 - C1 - - 5Y81 - - ? B:[4-1115] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WYQSINILESIQSNTSIDNT------------------------K-IIEANEDALLELYVNLQEEDMFYGLWRRRA--K-YT--E-TNIGL-SYEQ-I--WDKAQQL----YEVAQVKAR----------------QSEYALWED-----NWIQCAEKL---DVLTELAKHE-----------GFTDLLLECGWRV------RDALEQSVKSVM--------DVPTPRRQMFKTFLAL-QNFAESR------GDQEVRKLCDEGIQLSLIKW-----R--Y-TPAHKWLLHGFQQYMEFLEATQIYANL-----H----TTTAQEIKRILQAWRDRLP-----DVNMWNDLVTWRQHAFQVINNAYLPLI----PAL--RGYHEIAWVINRFAHVARKHNMPDVCISQLARIYT-------------------------------EAFLKLREQA-K-CHYQNMNELTTGLDVISN-----------------------GTVQKAEFFTLKGMFLSKL----------EANQ--AFAT-AV-QI------------DLNLAKAWAQWGFFNDRRLS---------EEP---------------------------------------------------------------------------SFASNAISCYLQAAGLYKN-SKIR-EL-LC-RILWLISIDDAS-------------------GMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKE------ANMVRHILIRIAKSYPQALHFQLR--TTKEDFAVI----------------------------------QP-WEYLQELNNILKT---A-----YPLLALSLESLVAQINDRFKSTTDEDLF-------------------RLINVLLI-------------------------------------DGTLNYNRLP--------------------------------------------------PENTEKNLVKFSTTLLAPYIRPKFNADFYETYIKRLRY-WRRRL----EN------------K-L--------------------D--R--------------------------------------------------------------------------------------------------------------------CPH-----LSNFHHQ----K------F--EDIEIP-------GQYLLNKDNNV---HFIKIARFLPTVDFV-RGTHSSYRRLMIRGHDGSVHSFAVQYPAV--RHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEF----CKKKGFD--P-DDIQD-FMAD--KL-N-AAHDDA---PDMTILKVEIFNSIQT-MFV--N-VLKDHFTSLF--FEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKPLLKN---------HDLDSP-I-FHN-NEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALFIRDEIISWFSNLHR----------------------------------------QLREMVQTNVDLIIRKVAQLGHL----N--STPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF
87 Fugue 30.5319% -9 - C1 - - 5H64 - - MTOR_HUMAN A:[210-2549] -----VAALRACLILTTQREPKEMQKPQWYRHTFEEAE--KGFDETLAKEKGM-----------------------------------NRDDRIHGALLILNELVRISSMEGERL-----------------------------------------REEM---EEITQQQL---------------------------------VHDKYCKDLMGFGTKPRHITPFTSFQAV-QP-QQSNALVGLLG-------------------------------YSS-H-Q-------------GLM---GFGTS--PSPAK----------------------------------------------------------STLVESRCCRD---------LMEEKFDQVCQWVLKCRN-----------------------------------------------SKNSLIQMTILNLLPRLAAFRPSAFTD---------------TQYLQDTMNHVLSCVKVLYDLSRQIPQLKKDIQDGLLKMLSLVL-------------------MHKPLRHPGM------PKGLAHQL-ASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCA-DHFLNSEHKEI-----RME-AARTCSRLLTPSIHLIS----------------------------------GH-AHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDER---FDAHLAQAENLQALFV---AL-NDQV---FEIRELAICTVGRL---------------------------------------------------SSMNPAFVMP-FLRKML------IQILTELEHSGIGR---IKEQ-S----ARMLGHLVSNAPRLIRPYMEPILKALIL--K-L-KD---------------------PDPDPN----PGVINNVLATIGELAQ-VSGLEMR-------------------------KWVDELFIIIMDMLQDSSLLAKRQVALW-------------------------------------------------------------------TLGQLVASTGYVVEPYRKYPTLLEVLLN-FLKTEQN-QGTRREAIRVLGLLGA-L-DPYKH------------------KVNIGMIDQSRDASAVSLSE--SKSSQDSSMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCV---------------------------Q---FLPQVMPTFLNVIRVCDGA--IREFLFQQLGMLVSFVKS-------------------------------------HIRPYMDEIVTLMREFWVMNT----------S---IQSTIIL-LIEQIVVALG--------GEFKLYLPQLIPHMLRVFMHDNSPGRIV---------SIKLLAA---IQLFG--AN-LDDYLHLLLPPIVK-----------------------------------------------LFDAPEA--PLPS-----RKAA--LETVDRLTE-------------SLDFTDYA------------------------------------------------------SRIIHPIVRTLDQSP-----------------------------------------------------------E--------LRSTAMDTLSSLVFQLGKKYQIF--------IPMV-----NKVLVRH--------------------------RINH----QRYDVLICRIVKGYT-LMKKLHVSTINL--QKAWG---------AA-----------RRVSKDDWLEWLRRLSLELLK--DSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELI--R--SIELALTSQDIAE-V-TQTLL-N-LAEFMEHSD----KGPLPLR---------D----------------DN-G---I-VL-LGERAAKCRAYAKA-----LHYKELEFQKGP-----------------------------------------T--PAILESLISINNKLQQPEAAAGVLEYAMKHFGEL--EIQ--A---TWYEKLHE-----WEDALVAYDKKMDTN------------------KDDPELMLGRMRCLEALG--------------------------------------------------EWGQLHQQCCEKWTLV------------NDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQC--I-DK--A-RDL-L-DAEL-TAMAGE---S----YS----------------------------------------RAYGAMVSCHMLSELEEVIQY-KLV----PERREIIRQIWWERLQ-------------------------GCQRIVEDWQKILMV-RS-----L-----VVS---PHEDMRTWLKYASLCGKS-G--R-LALAHKTLVLLLGVDPSRQLDHPLPT-----------V--HPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATE--DQQ----H--KQELHKLMARCFLKLGEWQLNLQG--INESTIPKVLQYYSA-----AT-----------EHD---RS--------WYK-A-WHAWAVMNFEAVLHYKHQN--------QA-R------DEK----------KKVTEDLSKTL----LMYTVPAVQ--GFF-RSI-SLSRG----------NNLQDTLRVLTLWFDYGHW------------P-----------DVNEALVEGVK--AIQIDTWLQVIPQLIARIDT-PRPL---VGRLIHQLLTDIG----RYHPQALIYPLTVASKS---T-TT-AR-H-NA-AN-KILKNMCEHSNT-------------------LVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKET--SFNQAYGRDLMEAQEWC-RKYMKSGN----------------------------------------------V-------K------------DLT-------------------QAWDLYYH-------------------------------------VF----------------------------R------R--------------------IS------------------------------------KQ-LPQL-----T-------------S-L--------------------E--L---Q-----------YV---------------------------S---------------------------P------KLL------------------M----C----------R-D-----LELAVP-----G------T--YDPN-------------------Q---PIIRIQSIAPSLQVI-T-SKQRPRKLTLMGSNGHEFVFLLKG--H--EDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALI-----RDYREKKKI--LLNIEHR-IMLR--MA-P-DYD------HLTLMQKVEVFEHAVN-NTAGD--DLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDC-----------FE---------VA---M-T-REKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNW---------------------------------------RLMDTNTALNKKAIQIINRVRDKLTGRDFS----H--DDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
74 HHSearch 29.5124% -11 - C1 - - 5FVM - - ? B:[1240-2469] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEDWQEWIRRLSI----ESS----SHALRACSGLAGIY-YPLARELFNASFA----------------QYQEDLIQSLCAALSS-----------------------------------TLLNLVEFMEHDD-K----------------------------------PLP-------ISISTLGEYAQRCHAYAKALHYKELEFIEEPS-------------------------------TSTIESLITINNQLHQTDAAIGILKHAQ--QHHD--LQLKE-T-WYEK-LQRWDDALNA----YNKREA------------------E------VTI-----GKMRSLHALGEWDQLSELAADKWA-SS--EVKRAIAPLAAGAAWGLAQWDRVEQYIEV-----M--------KPQSPDKAFFDAILCL-HR-----N-----NFEKAAEHIFSARDLLVTEMSAL-------YNRAYGVVVRTQMVAELEEIIQYKKLP-----Q----G--SERRAMIRKTWNKRLLGC-Q-NVDVWQRVLKVRSLVIKPKQ---------------------DMKVWIKFANLCRKSGRLGLAQKTLNTLLE----------------------APP---PVVYAQLKYMWAT-G-SQKEALNHLISFTSRMAHD--------LGL-QH----HIEDYTKLLARCFLKQGEWRVSLQPNWRLENPDAILG--SYLL-AT-HF------------DKTWYKAWHNWALANFEVTS---------SLTQRIKD-------DKVPPT-----------------------------------------LNAN-D--NFPPELVQRHVVPAIKGFFHSIAL-SQ--S-SLQD-TL-RLLTLWFKFGGI-------------------PEAAQAMHEGFGLIKIDNWLEVIPQLISRIHQPN---QTVSRSLLSLLADLGKAHPQALVYPLT--VAIKSD-----------------------------SV----SR---QRAALSIIDKMRM---H-----SPKLV-------N------------QAE-------------------LVSDELIR-------------------------------------VA----------------------------V------L--------------------WH------------------------------------EL-WYEGL----EDAS----------R-QFFGEHNTEKMFATLEPLHEML--KR--G-----------PE---------------------------TLREISFQNSFGRDLNDAYEWVLNYKRTK------DINNLNQAWDIYYNVFRRISRK----L----------P-Q-----LQTLDLQHVS-PKLSA--A--KDLELA--V---PGTY-------HAGKPIVRITHFEPVFTVI-S-SKQRPRRVIIKGSDGKDYQYLLKS--H--EDIRQDNLVMQLFGLVNTLLQNDPESFQRHLNIQQYPAIPLSPKTGLLGWVPNSDTFHVLIREH-------REASKIPLNIEHR-IMLQ--MA-P-DYD------NLTLLQKVEVFTYALD-NTK-GQ-DLYKVLWLKSRSSESWLDRRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRITGKVVHIDFGDC-----------FE---------AA---I-LREKY-PEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTHAVMEQTGIDLPLANPSELLRKGVISVEDAAKMELQQKAEVRNARATLVLKRIADKLTGND------FPRCQELSVPDQVDKLIQQATSVENLCQHYIGWCS--
75 HHSearch 27.5715% -16 - C1 - - 5OJS - - TRA1_YEAST T:[2561-3767] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSDFIDSLIEIFYQD-PKAIHRAWVTLFPQVYKS--IPK--N----EKYGFVRSIITLLSKPYHTR--------------------QISSRTNVINMLLDSISKIE---------------------------------------SLE-------LPPHLVKYLAISYNAWYQSINILESIQSNTSIDN-------------------------TKIIEANEDALLELYVNLQEEDMFYGLWRRRA--K-YT--E-TNI-GLSYEQ-IGLWDKAQQL----YEVAQVKARSGALPYSQSEYA---L------WED-----NWIQCAEKLQHWDVLTELAKHE---G--------FTDLLLECGWRVADWNSDRDALEQSVKSVM--------DVPTPRRQMFKTFLAL-QN-----FAESRKGDQEVRKLCDEGIQLSLIKWVSLPIR--Y-TPAHKWLLHGFQQYMEFLEATQIYANLHTTTVQNLDSK--AQEIKRILQAWRDRLPNT-WDDVNMWNDLVTWRQHAFQVINNAYLPLIPALQ---AYRGYHEIAWVINRFAHVARKHNMPDVCISQLARIYTLPNI-----EIQ----------EAF---LKLREQAKCHYQNMN-ELTTGLDVISN----TNLV--------------------YFGTVQKAEFFTLKGMFLSK------LRAYEEANQ--AF-ATAV-QI------------DLNLAKAWAQWGFFNDRRLS---------EEP------------------------------------------------------------------------NNISFASNAISCYLQAAGLYKN-SKIR-EL-LC-RILWLISIDDAS-------------------GMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKE------ANMVRHILIRIAKSYPQALHFQLR--TTKEDFAVIQ---------------------------------RQPWEYLQELNNILKT---A-----YPLLA-------L------------SLESLVAQINDRFKSTTDEDLFRLINVLLI-------------------------------------DGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNADFIDNKPDYETYIKRL------------------------------------RY-WRRRL----E-------------N-K--------------------LD-R---A-----------SK---------------------------K---------------------------E------NLE------------------V----L----------CPH-----LSNFHH-----QK-----F--EDIEIP-------GQYLLNKDNNV---HFIKIARFLPTVDFV-RGTHSSYRRLMIRGHDGSVHSFAVQY--PAVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNE----FCKKKGFD---PDDIQD-FMAD--KL-N-AAHDDALPAPDMTILKVEIFNSIQT-MFV-PSNVLKDHFTSLFTQFEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSDLS--------LP---------PD---SPI-FHN-NEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALFIRDEIISWFSNLHRPIIE----------------------------------NPQLREMVQTNVDLIIRKVAQLGHL----N--STPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF
77 HHSearch 25.5616% 1 - C1 - - 5OEJ - - ? B:[2540-3825] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGDILNPLIDI---S-AETIHNAWVVVFPVA-------S------RYELEFTRALVKLLFKDYHI--------------------------PNVIKSLLDGVGKC----------------------------------------------------PHLVKYLGSNYNAWYGAIKLLEELSEGQGIDN-------------------------QKISDANQDALLEVYMSLQEDDMFYGTWRRRA--K-YF--E-TNA-ALSYEQ-IGIWDKALQL----YEAAQIKARSGVFPFGESEYS---L------WED-----HWIYCAEKLQHWEILTELAKHE---G--------FTDLLLECGWRGADWIADREPLEQSVKTVM--------DIPTPRRQIFQTFLAL-QGFSQQKD-----TLQDVSRLCDEGIQLTLRKWNALPQR--V-TRAHIGLLHTFQQYVELMEASQVYSSLVTTNAQNLDVK--SQELKRVLQAWRERLPN----DINIWNDLVTWRQHVFGVINRV----------SYAYRGYHEMAWVINRFAHVARK-----VCINQLTK--------------------------AF---LKLREQAKC------SELNTGLDVIS-------------------------------ATQQKAEFFTLKGMFLAKLN------AKDEA-N--QAFATAV-QI------------DLNLPKAWAEWGFFNDRRFK---------ENP------------------------------------------------------------------------EEIFHAKNAISCYLQAAGLYKDGKT-R-KL-LC-RILWLISLDDAA-------------------GSLAKTFEDHHGESPVWYWITFVPQLLTSLSHKE------AKIVRHILIQIAKSYPQSLHFQLR--TTKEDYQ---------------------------TTD----SRQP-WQDVEEIMGILKT---A-----YPLLA-------L------------SLE-------------------SLVDQLNQRFKCNADEDAYRLVIVLYNDGVQQMNRPAATEASISRFA----------------------------D------S--------------------VLPKNIREVFEQDIIACNPNLETYISKL----------RK-WRDCL----E-------------EKL----------------------------------------G---------------------------K---------------------------A------DLE------------------RVSLHL----------S-LFHHQKFEDIEI-----P------G--QYLLHK--D-----NN-------N---HFIKIERFLPTLDLVRG-SNGCYKRMTIRGNDGSLHPFAVQFPAA--RHCRREERIFQLFRIFDDALSRKVQSRRRNISLTLPIAVPLSPHIRILNDDKRYTTLMGIYEEFCRRKGQS-------RDEPFA-YTIQ--KL-R-AAFDPRLPKPDIVSVRAEVLASIQS-TLV-PSTLLKDYYTEKFSNYENYWLFRKQFTAQYASFIFMTYIMCINSRQPQKIHINEGSGNIWT---STA-----------YNNSTLDPAVKAG---API-FYN-TESVPFRLTPNIQKFIGEAGLEGILSVYILVIANSLSDSEFDMEQYLSLFVRDEVISWFAQQHRASAQTN----------------------------------QLREIVRVNVELLTKRVLQLNHI----P--NSQNVATQFVLNLISQAVNPRNLAYTDSAWMAYL
8 PsiBlast_PDB 24.7432% 11 - C1 - - 6JXC - - ATM_YEAST A:[2108-2786] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WSSESR----LEPAAAIYE----------KIIVNWDINVED--HESCSDVFYTLGSFLDEQAQ---------KLRSNGEIEDREHRSYTGKSTLKALE--LIYK-----------AKRHY-NRVL---LQYNRDSEV----LKALLLQKEKFLWHALHFYLNTLVF-SN-RY-D-ND-IIDKFCGLWFENDDN-------------------SKINQLLYKEIGTIPSWKFLPWVNQIASKIS---MEENEFQKPLQLTMKRLLYKLPYDSLYSVM--SI-------LLYEKQSN-KDTNISQKIQAVKKIL-LELQGYDR---GAFAKKYLL--------------------------------------PVQ-------------------EFCEMSVE-------------------------------------LA----------------------------N------L--------------------KF------------------------------------VQ-NTKT-----L-------------R-L--------------------A--N---L-----------KI---------------------------G---------------------------Q------YWL------------------K----Q----------L-N-----MEKLPL-----P------TSNFTVKSS--A---DGRK-------A---RPYIVSVNETVGITT-T-GLSLPKIVTFNISDGTTQKALMKGS-N--DDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQIL----------SKLH--TNDKITFDQARK--GM-K-AVQ------TKSNEERLKAYLKITN-EIK-P--QLRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIA-----------FD---------QG---K-L-LPI-PELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSWVMSPVKK--YEHLFE-------------------------------NENQESYRALKGVEEKLM------------GNGLSVESSVQDLIQQATDPSNLSVIYMGWSPF-