@TOME V3
(Feb 2022)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Screening

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : BMP2K_HUMAN: (2020-09-05 )
MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITDTIGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGTIMDSSYSANRSVADKEAIANFTNQKNISNPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKDQRTGKKTSVQGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLMDSEDEEEEEKHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLNTILLTSAQLSSDVAVETPKQEFDVFGAVPFFAVRAQQPQQEKNEKNLPQHRFPAAGLEQEEFDVFTKAPFSKKVNVQECHAVGPEAHTIPGYPKSVDVFGSTPFQPFLTSTSKSESNEDLFGLVPFDEITGSQQQKVKQRSLQKLSSRQRRTKQDMSKSNGKRHHGTPTSTKKTLKPTYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRGNVLQPEESLLDPFGAKPFHSPDLSWHPPHQGLSDIRADHNTVLPGRPRQNSLHGSFHSADVLKMDDFGAVPFTELVVQSITPHQSQQSQPVELDPFGAAPFPSKQ

Atome Classification :

(37 SA) .........10........20........30........40........50........60........70-.-...-....80....----....90--.........100.......110.......----120-.-.-......130.......140..--.....-150.......160.......170..---.....180.......190.......200.......210..----.....220.......230.......240.......250.......260...---...-.270--......-.280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160
(Atome) (Ident) (Tito) (Num) (QMean) (pKd) (pKd) (Uniprot) MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITDTIGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGTIMDSSYSANRSVADKEAIANFTNQKNISNPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKDQRTGKKTSVQGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLMDSEDEEEEEKHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLNTILLTSAQLSSDVAVETPKQEFDVFGAVPFFAVRAQQPQQEKNEKNLPQHRFPAAGLEQEEFDVFTKAPFSKKVNVQECHAVGPEAHTIPGYPKSVDVFGSTPFQPFLTSTSKSESNEDLFGLVPFDEITGSQQQKVKQRSLQKLSSRQRRTKQDMSKSNGKRHHGTPTSTKKTLKPTYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRGNVLQPEESLLDPFGAKPFHSPDLSWHPPHQGLSDIRADHNTVLPGRPRQNSLHGSFHSADVLKMDDFGAVPFTELVVQSITPHQSQQSQPVELDPFGAAPFPSKQ
3 PsiBlast_PDB 98.1999%-153 - C1 - - 4W9W 6.4 - BMP2K_HUMAN A:[1-306] --------------------------------------VGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTAS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
262 HHSearch 97.2299%-152 - C1 - - 4W9W 6.4 - BMP2K_HUMAN A:[4-304] -----------------------------------------RVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22 Blastp_CBE 96.9599%-147 - C1 - - 5I3O 7.9 - BMP2K_HUMAN B:[1-302] -----------------------------------------RVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 96.7099%-153 - C1 - - 4W9X 6.7 - BMP2K_HUMAN A:[4-307] --------------------------------------VGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-------WEVLILMEYCRAGQVVNQMNK--K-QTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 96.3999%-145 - C1 - - 5I3O 7.4 - BMP2K_HUMAN A:[1-302] -----------------------------------------RVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 96.0899%-151 - C1 - - 5IKW 8.1 - BMP2K_HUMAN A:[7-303] -----------------------------------------RVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 Blastp_CBE 95.9299%-145 - C1 - - 5I3R 7.8 - BMP2K_HUMAN B:[1-302] -----------------------------------------RVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 95.7499%-141 - C1 - - 5I3R 7.8 - BMP2K_HUMAN A:[1-302] -----------------------------------------RVFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
261 HHSearch 94.8399%-146 - C1 - - 5I3R 7.8 - BMP2K_HUMAN A:[2-296] ------------------------------------------VFAVGRHQVTLEESLAEGGFSTVFLVRTH-G-GIR-CALKRMYVNN----MPDLN---VCKREITIMKELSGHKNIVGYLDCAVNSI----S-D-N-V-WEVLILMEYCRAGQVVNQMNK--KLQTG-FTEPEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGV----NVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSAL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 89.9976%-143 - C1 - - 5TE0 7.3 - AAK1_HUMAN A:[4-320] --------------------------------GLGSGYIG-RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----------V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
260 HHSearch 84.6180%-158 - C1 - - 5TE0 7.3 - AAK1_HUMAN A:[12-292] -----------------------------------------RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----------V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 Blastp_CBE 84.6076%-154 - C1 - - 5L4Q 7.6 - AAK1_HUMAN B:[7-307] ------------------------------------GYIG-RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----------V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---F-------------NF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 82.5276% -70 - C1 - - 4WSQ 9.7 - AAK1_HUMAN A:[1-317] --------------------------------GLGSGYIG-RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----S-SGD-V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 Blastp_CBE 81.0177% -68 - C1 - - 4WSQ 9.6 - AAK1_HUMAN B:[5-314] ------------------------------------GYIG-RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----S-SGD-V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
263 HHSearch 78.1279% -76 - C1 - - 4WSQ 9.7 - AAK1_HUMAN A:[9-295] -----------------------------------------RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----SSG-D-V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---FGE-SQVA--ICDGNF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 77.5776% -75 - C1 - - 5L4Q 7.5 - AAK1_HUMAN A:[7-309] ------------------------------------GYIG-RVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-N-GMK-CALKRMFVNN----EHDLQ---VCKREIQIMRDLSGHKNIVGYIDSSINNV----S-SGD-V-WEVLILMDFCRGGQVVNLMNQ--RLQTG-FTENEVLQIFCDTCEAVARLHQCKT---PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGV----NAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLP---F-------------NF-TIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13 PsiBlast_PDB 60.8142% -19 - C1 - - 5Y7Z 6.1 - GAK_HUMAN A:[2-289] ---------------------------------SQSDFVGQTV-ELGELRLRVRRVLAEGGFAFVYEAQDV-GSGRE-YALKRLLSNE----EEKNR---AIIQEVCFMKKLSGHPNIVQF--CSAASIGKEES-D-TGQ-AEFLLLTELCK-GQLVEFLKK--MESRGPLSCDTVLKIFYQTCRAVQHMHRQKP---PIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHP---FEDGAKLR--IVNGKY-SIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 60.5742% -26 - C1 - - 5Y80 5.7 - GAK_HUMAN A:[2-289] ---------------------------------SQSDFVGQTV-ELGELRLRVRRVLAEGGFAFVYEAQDV-GSGRE-YALKRLLSNE----EEKNR---AIIQEVCFMKKLSGHPNIVQF--CSAASIGKEES-D-TGQ-AEFLLLTELCK-GQLVEFLKK--M---GPLSCDTVLKIFYQTCRAVQHMHRQKP---PIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHP---FEDGAKLR--IVNGKY-SIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 Blastp_CBE 59.9842% -21 - C1 - - 5Y7Z 5.7 - GAK_HUMAN B:[2-289] ---------------------------------SQSDFVGQTV-ELGELRLRVRRVLAEGGFAFVYEAQDV-GSGRE-YALKRLLSNE----EEKNR---AIIQEVCFMKKLSGHPNIVQF--CSAASIGKEES-D-TGQ-AEFLLLTELCK-GQLVEFLKK--MESRGPLSCDTVLKIFYQTCRAVQHMHRQKP---PIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHP---FEDGAKLR--IVNGKY-SIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 58.3142% -16 - C1 - - 4C57 - - GAK_HUMAN A:[24-300] ---------------------------------------------LGELRLRVRRVLAEGGFAFVYEAQDV-GSGRE-YALKRLLSNE----EEKNR---AIIQEVCFMKKLSGHPNIVQF--CSAASIGKEES-D-T-GQAEFLLLTELCK-GQLVEFLKK--MESRGPLSCDTVLKIFYQTCRAVQHMHRQKP---PIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHP---FEDGAKLR--IVNGKY-SIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 Blastp_CBE 53.3643% -51 - C1 - - 4Y8D 4.7 - GAK_HUMAN B:[24-300] ---------------------------------------------LGELRLRVRRVLAEGGFAFVYEAQDV-GSGRE-YALKRLLSNE----EEKNR---AIIQEVCFMKKLSGHPNIVQF--CSAASIGKEES-D-T-GQAEFLLLTELCK-GQLVEFLKK--MESRGPLSCDTVLKIFYQTCRAVQHMHRQKP---PIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYP--------------------------------YSNFPIGEKQDIWALGCILYLLCFRQHP---F----------------SIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12 PsiBlast_PDB 53.0442% -51 - C1 - - 4Y8D 5.6 - GAK_HUMAN A:[24-300] ---------------------------------------------LGELRLRVRRVLAEGGFAFVYEAQDV-GSGRE-YALKRLLSNE----EEKNR---AIIQEVCFMKKLSGHPNIVQF--CSAASIGKEES-D-T-GQAEFLLLTELCK-GQLVEFLKK--MESRGPLSCDTVLKIFYQTCRAVQHMHRQKP---PIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYP--------------------------------YSNFPIGEKQDIWALGCILYLLCFRQHP---F----------------SIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
98 Blastp_CBE 37.8431% -36 - C1 - - 3QHW 5.4 - CDK2_HUMAN A:[10-199] ------------------------------------------------------EKIGEGTYGVVYKARNKLT-GEV-VALKKIRLDTETEGVPSTA---I--REISLLKELN-HPNIVKLLDVIH-------T-E-N----KLYLVFEFLHQ-DLKKFMDA--SALTG-IPLPLIKSYLFQLLQGLAFCHSHR-----VLHRDLKPQNLLINTEGAIKLADFGLA-RAFGVPVRTYH----EVV--------TLWYRAPEI--LLGCKYYSTAVDIWSLGCIFAEMV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
99 Blastp_CBE 37.5131% -35 - C1 - - 3QHR 2.7 - CDK2_HUMAN C:[10-199] ------------------------------------------------------EKIGEGTYGVVYKARNKLT-GEV-VALKKIRLDTETEGVPSTA---I--REISLLKELN-HPNIVKLLDVIH-------T-E-N----KLYLVFEFLHQ-DLKKFMDA--SALTG-IPLPLIKSYLFQLLQGLAFCHSHR-----VLHRDLKPQNLLINTEGAIKLADFGLA-RAFGVPVRTYH----EVV--------TLWYRAPEI--LLGCKYYSTAVDIWSLGCIFAEMV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97 Blastp_CBE 37.2731% -37 - C1 - - 3QHW 2.5 - CDK2_HUMAN C:[10-199] ------------------------------------------------------EKIGEGTYGVVYKARNKLT-GEV-VALKKIRLDTETEGVPSTA---I--REISLLKELN-HPNIVKLLDVIH-------T-E-N----KLYLVFEFLHQ-DLKKFMDA--SALTG-IPLPLIKSYLFQLLQGLAFCHSHR-----VLHRDLKPQNLLINTEGAIKLADFGLA-RAFGVPVRTYH----EVV--------TLWYRAPEI--LLGCKYYSTAVDIWSLGCIFAEMV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100 Blastp_CBE 36.8731% -36 - C1 - - 3QHR 2.7 - CDK2_HUMAN A:[10-199] ------------------------------------------------------EKIGEGTYGVVYKARNKLT-GEV-VALKKIRLDTETEGVPSTA---I--REISLLKELN-HPNIVKLLDVIH-------T-E-N----KLYLVFEFLHQ-DLKKFMDA--SALTG-IPLPLIKSYLFQLLQGLAFCHSHR-----VLHRDLKPQNLLINTEGAIKLADFGLA-RAFGVPVRTYH----EVV--------TLWYRAPEI--LLGCKYYSTAVDIWSLGCIFAEMV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129 Blastp_CBE 36.7731% -39 - C1 - - 6GVA 2.9 - CDK2_HUMAN A:[9-198] ------------------------------------------------------EKIGEGTYGVVYKARNKLT-GEV-VALKKIRLD-TEG-VPSTA---I--REISLLKELN-HPNIVKLLDVIH-------T-E-N----KLYLVFEFLHQ-DLKKFMDA--SALTG-IPLPLIKSYLFQLLQGLAFCHSHR-----VLHRDLKPQNLLINTEGAIKLADFGLA-RAFGVPVRTYH----EVV--------TLWYRAPEI--LLGCKYYSTAVDIWSLGCIFAEMV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31 Blastp_CBE 34.8931% -46 - C1 - - 5M53 3.5 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGL--------------------------VGTPYYMSPEQMNRMS---YNEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 Blastp_CBE 34.2131% -49 - C1 - - 5M51 3.9 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGD----------------------F------VGTPYYMSPEQMNRMS---YNEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 Blastp_CBE 33.6531% -43 - C1 - - 2XNP 4.8 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS-------HRDLKPANVFLDGKQNVKLGDFGL-------------------F------VGTPYYMSPEQMNR------NEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 Blastp_CBE 33.4931% -34 - C1 - - 2W5A 3.3 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS------LHRDLKPANVFLDGKQNVKLGDFGLA--RIL---TSFA----KTF------VGTPYYMSPEQMNRM----YNEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 Blastp_CBE 32.8931% -35 - C1 - - 2JAV 5.0 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIID----------T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS---------DLKPANVFLDGKQNVKLGDFGLA--RIL---------------------GTPYYMSPEQMNRMS---YNEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 Blastp_CBE 32.4931% -51 - C1 - - 2XNO 2.4 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS--------RDLKPANVFLDGKQNVKLGDF---------------------F------VGTPYYMSPEQMNR------NEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 Blastp_CBE 32.0331% -42 - C1 - - 2XNN 3.7 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS--------RDLKPANVFLDGKQNVKLGDFG--------------------F------VGTPYYMSPEQMNR-----YNEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 Blastp_CBE 31.4831% -33 - C1 - - 4AFE 4.8 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS-------HRDLKPANVFLDGKQNVKLGDFGL--------------------------VGTPYYMSPEQMNR------NEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46 Blastp_CBE 31.0231% -40 - C1 - - 2XK3 3.9 - NEK2_HUMAN A:[55-265] --------------------------------------------------------------------------------------------------------EVNLLRELK-HPNIVRYYDRIIDRT----N-T-T-L-Y---IVMEYCEGGDLASVITKGTKERQY-LDEEFVLRVMTQLTLALKECHRRS--------RDLKPANVFLDGKQNVKLGDFG---------------------------VGTPYYMSPEQMNR------NEKSDIWSLGCLLYELCALMPPFTAFSQ-KELAGKIREGKFRRIP--YRYSDELNEIITRMLNLKDYHRPSVEEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
195 Blastp_CBE 30.6331% -17 - C1 - - 1UA2 5.4 - CDK7_HUMAN A:[18-212] --------------------------------------------------------LGEGQFATVYKARDK-N-TNQIVAIKK--------------INRTALREIKLLQELS-HPNIIGLLDAFGHK-------S-N-I-SLVFDFME--TDLEVIIKDNS--LV----LTPSHIKAYMLMTLQGLEYLHQ--H---WILHRDLKPNNLLLDENGVLKLADFGLAKS-FGSPNRAYH----QVV--------TRWYRAPEL--LFGARMYGVGVDMWAVGCILAEL-LLRVP---F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------