@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MYLK4_HUMAN: (2019-05-24 )
MLKVKRLEEFNTCYNSNQLEKMAFFQCREEVEKVKCFLEKNSGDQDSRSGHNEAKEVWSNADLTERMPVKSKRTSALAVDIPAPPAPFDHRIVTAKQGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQKKKNRGSDAQDFVTK
Atome Classification :
(3 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MLK
V
K
R
L
E
E
F
N
T
CYNS
N
Q
L
E
K
M
A
F
F
Q
C
R
E
E
V
E
K
V
K
C
F
L
EKNSGDQDSRSG
H
N
E
A
K
E
V
WSNAD
L
T
ERMPVKSKRT
S
A
L
A
V
DIPAPPAPFDH
R
I
V
T
AKQGAVN
S
F
Y
T
V
S
K
T
E
I
LGGGRFG
Q
V
H
K
C
E
E
TAT
G
L
K
L
A
A
K
I
I
K
TRGMK
D
K
E
E
V
K
N
E
I
S
V
M
N
QLD
H
A
N
L
I
Q
L
Y
D
A
FESKN
D
I
V
L
V
M
E
YVD
G
G
E
L
F
D
R
I
I
DESY
N
L
T
E
L
D
T
I
L
F
M
K
Q
I
C
E
G
I
R
H
M
H
Q
M
Y
I
L
H
L
DLKPE
N
I
L
C
VNRDA
K
Q
I
K
I
I
D
F
G
L
A
RRYKPR
E
K
L
K
V
NFGTPEFLAPEVVNYDFVSF
P
T
D
M
W
S
V
G
V
I
A
Y
M
L
L
SGL
S
P
FLGDN
D
A
E
T
L
N
N
I
L
A
C
RWDL
E
D
E
E
F
Q
D
I
S
E
E
A
K
E
F
I
S
K
L
L
IKEKS
W
R
I
S
A
S
E
ALKHPWLS
D
H
K
L
H
S
R
L
N
A
Q
K
KKNRGS
D
A
Q
D
FVTK
21
Blastp_CBE
95.08
99%
-129
- C1 -
-
2X4F
3
MYLK4_HUMAN
B:
[66-355]
--------------------------------------------------------------------------------
I
P
A
P
P
A
P
F
D
H
R
I
V
T
A
K
Q
G
A
V
N
S
F
Y
T
V
S
K
T
E
I
L
G
G
G
--
G
Q
V
H
K
C
E
E
T
A
T
G
L
K
L
A
A
K
I
I
K
T
R
G
M
K
D
K
E
E
V
K
N
E
I
S
V
M
N
Q
L
D
H
A
N
L
I
Q
L
Y
D
A
F
E
S
K
N
D
I
V
L
V
M
E
Y
V
D
G
G
E
L
F
D
R
I
I
D
E
S
Y
N
L
T
E
L
D
T
I
L
F
M
K
Q
I
C
E
G
I
R
H
M
H
Q
M
Y
I
L
H
L
D
L
K
P
E
N
I
L
C
V
N
R
D
A
K
Q
I
K
I
I
D
F
G
L
A
R
R
Y
K
P
R
E
K
L
K
V
N
F
G
T
P
E
F
L
A
P
E
V
V
N
Y
D
F
V
S
F
P
T
D
M
W
S
V
G
V
I
A
Y
M
L
L
S
G
L
S
P
F
L
G
D
N
D
A
E
T
L
N
N
I
L
A
C
R
W
D
L
E
D
E
E
F
Q
D
I
S
E
E
A
K
E
F
I
S
K
L
L
I
K
E
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
L
S
D
H
K
L
H
S
R
L
------------------
38
HHSearch
94.43
100%
-122
- C1 -
-
2X4F
4
MYLK4_HUMAN
A:
[65-358]
-------------------------------------------------------------------------------
D
I
P
A
P
P
A
P
F
D
H
R
I
V
T
A
K
Q
G
A
V
N
S
F
Y
T
V
S
K
T
E
I
L
G
-----
Q
V
H
K
C
E
E
T
A
T
G
L
K
L
A
A
K
I
I
K
T
R
G
M
K
D
K
E
E
V
K
N
E
I
S
V
M
N
Q
L
D
H
A
N
L
I
Q
L
Y
D
A
F
E
S
K
N
D
I
V
L
V
M
E
Y
V
D
G
G
E
L
F
D
R
I
I
D
E
S
Y
N
L
T
E
L
D
T
I
L
F
M
K
Q
I
C
E
G
I
R
H
M
H
Q
M
Y
I
L
H
L
D
L
K
P
E
N
I
L
C
V
N
R
D
A
K
Q
I
K
I
I
D
F
G
L
A
R
R
Y
K
P
R
E
K
L
K
V
N
F
G
T
P
E
F
L
A
P
E
V
V
N
Y
D
F
V
S
F
P
T
D
M
W
S
V
G
V
I
A
Y
M
L
L
S
G
L
S
P
F
L
G
D
N
D
A
E
T
L
N
N
I
L
A
C
R
W
D
L
E
D
E
E
F
Q
D
I
S
E
E
A
K
E
F
I
S
K
L
L
I
K
E
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
L
S
D
H
K
L
H
S
R
L
S
A
Q
---------------
1
PsiBlast_PDB
94.20
99%
-122
- C1 -
-
2X4F
4
MYLK4_HUMAN
A:
[65-358]
-------------------------------------------------------------------------------
D
I
P
A
P
P
A
P
F
D
H
R
I
V
T
A
K
Q
G
A
V
N
S
F
Y
T
V
S
K
T
E
I
L
G
-----
Q
V
H
K
C
E
E
T
A
T
G
L
K
L
A
A
K
I
I
K
T
R
G
M
K
D
K
E
E
V
K
N
E
I
S
V
M
N
Q
L
D
H
A
N
L
I
Q
L
Y
D
A
F
E
S
K
N
D
I
V
L
V
M
E
Y
V
D
G
G
E
L
F
D
R
I
I
D
E
S
Y
N
L
T
E
L
D
T
I
L
F
M
K
Q
I
C
E
G
I
R
H
M
H
Q
M
Y
I
L
H
L
D
L
K
P
E
N
I
L
C
V
N
R
D
A
K
Q
I
K
I
I
D
F
G
L
A
R
R
Y
K
P
R
E
K
L
K
V
N
F
G
T
P
E
F
L
A
P
E
V
V
N
Y
D
F
V
S
F
P
T
D
M
W
S
V
G
V
I
A
Y
M
L
L
S
G
L
S
P
F
L
G
D
N
D
A
E
T
L
N
N
I
L
A
C
R
W
D
L
E
D
E
E
F
Q
D
I
S
E
E
A
K
E
F
I
S
K
L
L
I
K
E
K
S
W
R
I
S
A
S
E
A
L
K
H
P
W
L
S
D
H
K
L
H
S
R
L
S
A
Q
---------------