@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Screening
Virtual Screening Score
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : KIT_HUMAN: (2019-04-30 )
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
Atome Classification :
(9 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(pKd)
(pKd)
(Uniprot)
MRGAR
G
A
W
D
F
L
C
V
L
L
L
L
L
R
VQTGSSQPSVSPGEPSPPSIHPGKS
D
L
I
V
R
VG
D
E
I
R
L
L
CTDPG
F
V
K
W
T
F
E
I
LDETNENKQNE
W
I
TEKAEATNTG
K
Y
T
CTNKHGLSN
S
I
Y
V
F
VRDP
A
K
L
F
L
V
DRSLYGKEDND
T
L
V
RCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKA
G
I
M
I
K
S
V
K
R
A
Y
H
R
L
C
L
HCSVDQ
E
G
K
S
V
L
S
E
K
F
I
L
K
VRPAFKAV
P
V
V
S
V
S
K
A
S
Y
L
LREGE
E
F
T
V
T
C
T
I
K
D
V
S
S
S
V
Y
S
T
W
KREN
S
Q
T
K
L
Q
E
K
YNSWHHGDFN
Y
E
R
Q
A
T
L
T
I
S
S
A
RVNDS
G
V
F
M
C
Y
ANNTFGSAN
V
T
T
T
L
E
V
V
DKG
F
I
N
I
F
P
MIN
T
T
V
F
V
NDGE
N
V
D
L
I
V
E
YEAFPKPEH
Q
Q
W
I
Y
MNRTF
T
D
K
WEDYPKSENESN
I
R
Y
V
S
E
L
H
L
T
R
LKGTEGG
T
Y
T
F
L
V
SNSDV
N
A
A
I
A
F
N
V
Y
VNTKP
E
I
L
T
Y
D
R
L
V
N
G
M
L
Q
C
V
AAGFPEP
T
I
D
W
Y
FCPGTEQRCSASV
L
P
V
D
V
Q
TLNSSGPPF
G
K
L
V
V
QSSIDSSAFKHN
G
T
V
E
C
K
A
YNDVGK
T
S
A
Y
F
N
F
A
F
KGNNKEQIH
P
H
T
L
F
T
P
L
L
I
G
F
V
I
V
A
G
M
M
C
I
I
V
M
I
L
T
Y
K
Y
L
QK
P
M
Y
E
V
Q
W
K
V
V
E
EINGN
N
Y
V
Y
IDPTQLPYDHKWEFPR
N
R
L
SFGKTLGA
G
A
F
G
K
V
V
E
A
T
A
YGLIKSDA
A
M
T
V
A
V
K
MLKPSAH
L
T
E
R
E
A
L
M
S
E
L
K
V
L
S
Y
L
GNH
M
N
I
V
N
L
L
G
ACTIGG
P
T
L
V
I
TEYC
C
Y
G
D
L
L
N
F
L
R
R
K
R
D
SFICSKQE
D
H
A
E
A
A
L
Y
K
N
L
L
HSKESSCSDSTNEYMDMKPGV
S
Y
VVPTKADKRRSVRI
G
S
Y
I
E
RDVTPAIMED
D
E
L
AL
D
L
E
D
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
ASK
N
C
I
H
R
D
L
A
AR
N
I
L
LTHGR
I
T
K
I
CDFG
L
A
RDIKNDS
N
Y
V
V
KGN
A
R
L
P
V
K
WM
A
P
E
S
I
F
N
C
V
Y
T
FES
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
LGSSPYPGMPV
D
S
K
F
Y
K
M
I
K
E
G
F
R
MLSPEHA
P
A
E
M
Y
D
I
M
K
T
CWDADPLKR
P
T
F
K
Q
I
V
Q
L
I
E
K
Q
I
S
E
S
T
N
H
I
Y
S
N
L
ANCSPNRQKPVVDH
S
V
R
I
NSVGSTASSSQ
P
L
L
VHDDV
24
Blastp_CBE
33.14
97%
-137
- C2 -
-
3G0E
2.8
-
?
A:
[147-332]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
I
C
S
K
T
S
P
A
I
M
E
D
D
E
L
A
L
D
L
E
D
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
R
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
V
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
C
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
L
S
P
E
H
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
L
K
R
P
T
F
K
Q
I
V
Q
L
I
E
K
Q
I
S
E
S
---------------------------------------------
26
Blastp_CBE
31.00
95%
-136
- C2 -
-
6GQM
4.6
-
A:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
30
Blastp_CBE
30.93
95%
-136
* C2 *
-
6GQK
4.6
-
?
A:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
29
Blastp_CBE
30.77
95%
-138
- C2 -
-
6GQK
4.6
-
?
B:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
32
Blastp_CBE
30.47
95%
-132
- C2 -
-
6GQJ
5.4
-
?
A:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
25
Blastp_CBE
30.19
95%
-135
- C2 -
-
6GQM
4.5
-
?
B:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
28
Blastp_CBE
30.04
95%
-133
- C2 -
-
6GQL
4.8
-
KIT_HUMAN
A:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
31
Blastp_CBE
29.90
95%
-134
- C2 -
-
6GQJ
5.2
-
?
B:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------
27
Blastp_CBE
29.67
95%
-134
- C2 -
-
6GQL
4.8
-
KIT_HUMAN
B:
[158-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
H
L
L
S
F
S
Y
Q
V
A
K
G
M
A
F
L
A
S
K
N
C
I
H
R
D
L
A
A
R
N
I
L
L
T
H
G
N
I
T
K
I
C
D
F
G
L
A
R
D
I
K
N
D
S
N
Y
V
D
K
G
N
A
R
L
P
V
K
W
M
A
P
E
S
I
F
N
S
V
Y
T
F
E
S
D
V
W
S
Y
G
I
F
L
W
E
L
F
S
L
G
S
S
P
Y
P
G
M
P
V
D
S
K
F
Y
K
M
I
K
E
G
F
R
M
S
S
P
E
Y
A
P
A
E
M
Y
D
I
M
K
T
C
W
D
A
D
P
D
K
R
P
T
F
K
Q
I
V
Q
D
I
E
K
Q
I
S
E
S
---------------------------------------------