@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : M3K7_HUMAN: (2019-05-01 )
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
Atome Classification :
(18 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300...----....310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSTASAASSSSSSSAG
E
M
I
EA
P
S
Q
VLNFEEID
Y
K
E
I
E
V
E
E
V
VGRGA
F
G
V
V
C
KAKWRAKDV
A
I
K
Q
IE
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
SRVNHP
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
EYAEGG
S
L
Y
N
V
LHGAEPL
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
CS
Q
G
V
A
Y
L
H
SM
Q
P
K
A
L
I
HRDLKPP
N
L
L
L
VAG
G
T
V
L
K
ICDFGTA
C
D
I
Q
T
H
MTNNKGSAAWMA
P
E
VFEGSNYSEKCD
V
F
S
W
G
I
I
L
W
E
V
I
TRRK
P
F
D
EIGG
P
A
F
R
I
M
W
A
VHNGTRP
P
L
I
K
NL
P
K
P
I
E
S
L
M
T
R
CWSKDPSQRP
S
M
E
E
I
V
K
I
M
T
H
L
M
R
YFPGADEPLQYPCQYS----DEGQSNSATSTG
S
F
M
D
I
ASTNTSNKSDTNMEQVPAT
N
D
T
I
K
R
L
E
S
K
L
L
K
N
Q
A
K
Q
QSESG
R
L
S
LGASRGSSVESLPPTSEGKRMSA
D
M
S
E
I
E
A
R
I
A
A
TTAYSKPKRGHRKTASFGNILDV
P
E
I
V
I
SGNGQPRR
R
S
I
Q
D
L
T
V
TGTEPGQVSSRSSSP
S
V
R
M
I
TTSGPTSEKPTRSHPWTPDDSTDTNGSDNSI
P
M
A
Y
L
T
LDHQLQPLAPCPNS
K
E
S
M
A
V
F
E
Q
H
C
K
M
A
Q
E
Y
M
K
V
Q
T
E
I
A
L
L
L
Q
R
K
Q
E
L
V
A
ELDQDE
K
D
Q
Q
N
T
S
R
L
V
Q
E
H
K
K
L
L
DENK
S
L
S
T
Y
Y
Q
Q
C
K
K
Q
L
E
V
I
R
S
Q
Q
Q
KRQGTS
7
PsiBlast_PDB
85.45
91%
-135
- C1 -
-
4L3P
1
M3K7_HUMAN
A:
[6-308]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
-------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
85.41
91%
-133
- C1 -
-
5JGB
1
M3K7_HUMAN
A:
[6-307]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
84.38
92%
-136
- C1 -
-
2YIY
1
M3K7_HUMAN
A:
[5-304]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
-------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
83.33
92%
-133
* C1 *
-
4L52
1
M3K7_HUMAN
A:
[6-305]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
83.15
91%
-137
- C1 -
-
5GJG
1
M3K7_HUMAN
A:
[6-307]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
--------------
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LP----
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
83.06
92%
-138
- C1 -
-
5J9L
1
M3K7_HUMAN
A:
[5-304]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
--
G
V
V
C
K
A
-
W
R
A
-
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
--
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
--------------
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
82.67
91%
-133
- C1 -
-
4O91
1
M3K7_HUMAN
A:
[5-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
-------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
82.28
91%
-137
- C1 -
-
5JH6
1
M3K7_HUMAN
A:
[5-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
-
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
---
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
--------------
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
82.19
92%
-133
- C1 -
-
2EVA
1
M3K7_HUMAN
A:
[5-304]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
81.48
92%
-130
- C1 -
-
5V5N
1
M3K7_HUMAN
A:
[5-304]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
80.27
91%
-129
- C1 -
-
5JGA
1
M3K7_HUMAN
A:
[6-307]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
A
-----------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
80.20
91%
-136
- C1 -
-
5J8I
1
M3K7_HUMAN
A:
[5-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
--
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
-
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
---------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.09
91%
-143
- C1 -
-
5J7S
1
M3K7_HUMAN
A:
[5-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
--
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
--------
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
---
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
--------------
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
78.46
91%
-127
- C1 -
-
5JGD
1
M3K7_HUMAN
A:
[6-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
A
-----------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.20
91%
-145
- C1 -
-
5E7R
1
M3K7_HUMAN
A:
[5-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
---
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
---------------
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
-------------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
78.08
92%
-128
- C1 -
-
4L53
3
M3K7_HUMAN
A:
[6-305]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
-----------
K
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LPPG
E
D
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
77.49
91%
-125
- C1 -
-
5GJF
1
M3K7_HUMAN
A:
[6-307]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
-----
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
A
C
D
I
Q
T
H
M
T
N
N
K
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LP----
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
74.30
91%
-123
- C1 -
-
5GJD
1
M3K7_HUMAN
A:
[6-306]
------------------------------
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
G
A
F
G
V
V
C
K
A
K
W
R
A
K
D
V
A
I
K
Q
I
E
S
E
S
E
R
K
A
F
I
V
E
L
R
Q
L
S
R
V
N
H
P
N
I
V
K
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
A
E
G
G
S
L
Y
N
V
L
H
G
A
E
P
L
P
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
A
L
I
H
R
D
L
K
P
P
N
L
L
L
V
A
G
G
T
V
L
K
I
C
D
F
G
T
A
C
----------
G
S
A
A
W
M
A
P
E
V
F
E
G
S
N
Y
S
E
K
C
D
V
F
S
W
G
I
I
L
W
E
V
I
T
R
R
K
P
F
D
E
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
R
P
P
L
I
K
N
L
P
K
P
I
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
P
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
F
P
G
A
D
E
P
L
Q
Y
P
C
Q
H
S
LP----
G
R
V
E
P
Y
V
D
F
A
E
F
Y
R
L
W
S
V
D
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------