@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PTK6_HUMAN: (2019-05-03 )
MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSYENPT
Atome Classification :
(10 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MVSRDQAHLGP
K
Y
V
G
L
WDFKSRTDEELSFRAG
D
V
F
H
V
A
RKEE
Q
W
W
W
A
T
L
L
D
EAGGAVAQGYVPHNYLAERETVESEP
W
F
F
G
C
I
S
R
S
E
A
V
R
R
L
Q
AEGNA
T
G
A
F
L
I
R
VSEKPSA
D
Y
V
L
S
VR
D
T
Q
A
V
R
H
Y
K
I
W
R
RAG
G
R
L
H
L
N
E
A
V
S
F
LS
L
P
E
L
V
N
Y
H
R
A
Q
S
L
SHGLRLAAPCRKHEPEPLPHWD
D
W
E
R
P
R
E
E
F
T
L
C
R
K
LGSG
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
ISRD
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
SVGD
P
V
Y
I
I
T
E
L
MAK
G
S
L
L
E
L
L
RDSDEKVL
P
V
S
E
L
L
D
I
A
W
Q
V
AE
G
M
C
Y
LESQ
N
Y
I
H
R
D
L
A
AR
N
I
LVGENTLCKVG
D
F
G
L
A
R
L
I
K
E
D
V
Y
LSHDHNI
P
Y
KWT
A
P
E
A
L
SRGHYST
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
SRGQVPYPGMSNH
E
A
F
L
R
VDAGYRMPCPLECP
P
S
V
H
K
L
M
L
T
C
WCRDPEQR
P
C
F
K
A
L
R
E
R
L
S
S
F
TSYENPT
26
Blastp_CBE
46.96
98%
-138
- C1 -
-
5H2U
4
PTK6_HUMAN
B:
[2-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
-
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
---
23
Blastp_CBE
45.87
98%
-133
- C1 -
-
5D7V
3
PTK6_HUMAN
B:
[2-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
D
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
---
5
PsiBlast_PDB
44.67
98%
-134
- C1 -
-
5H2U
4
PTK6_HUMAN
A:
[2-266]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
-
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
H
--
4
PsiBlast_PDB
44.54
99%
-134
- C1 -
-
5DA3
3
PTK6_HUMAN
A:
[2-264]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
-
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
D
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
----
21
Blastp_CBE
44.01
98%
-131
* C1 *
-
5D7V
3
PTK6_HUMAN
D:
[2-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
D
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
---
24
Blastp_CBE
43.73
98%
-137
- C1 -
-
5H2U
4
PTK6_HUMAN
D:
[2-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
-
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
---
25
Blastp_CBE
43.63
98%
-135
- C1 -
-
5H2U
4
PTK6_HUMAN
C:
[2-266]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
-
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
H
--
1
PsiBlast_PDB
43.60
99%
-120
- C1 -
-
6CZ3
1
PTK6_HUMAN
A:
[3-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
A
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
D
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
C
F
K
A
L
R
E
R
L
S
S
--------
22
Blastp_CBE
43.07
98%
-133
- C1 -
-
5D7V
3
PTK6_HUMAN
C:
[2-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
D
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
D
H
N
I
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
T
F
K
A
L
R
E
R
L
S
S
F
T
S
H
H
---
2
PsiBlast_PDB
39.74
99%
-139
- C1 -
-
6CZ4
1
PTK6_HUMAN
A:
[4-264]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
E
V
F
E
G
L
W
K
D
R
V
Q
V
A
I
K
V
I
S
R
D
N
L
L
H
Q
Q
M
L
Q
S
E
I
Q
A
M
K
K
L
R
H
K
H
I
L
A
L
Y
A
V
V
S
V
G
D
P
V
Y
I
I
T
E
L
M
A
K
G
S
L
L
E
L
L
R
D
S
D
E
K
V
L
P
V
S
E
L
L
D
I
A
W
Q
V
A
E
G
M
C
Y
L
E
S
Q
N
Y
I
H
R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
A
R
L
I
K
E
D
V
Y
L
S
H
----
P
Y
K
W
T
A
P
E
A
L
S
R
G
H
Y
S
T
K
S
D
V
W
S
F
G
I
L
L
H
E
M
F
S
R
G
Q
V
P
Y
P
G
M
S
N
H
E
A
F
L
R
V
D
A
G
Y
R
M
P
C
P
L
E
C
P
P
S
V
H
K
L
M
L
T
C
W
C
R
D
P
E
Q
R
P
C
F
K
A
L
R
E
R
L
S
S
--------