@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SLK_HUMAN: (2019-05-04 )
MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
Atome Classification :
(5 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MS
F
F
N
F
R
K
I
F
K
LG
S
E
K
K
K
K
Q
Y
E
H
V
KRDL
N
P
E
D
F
W
E
I
I
G
ELGDGAFG
K
V
Y
KAQNKET
S
V
L
A
A
A
K
VIDTK
S
E
E
E
L
E
D
Y
M
V
E
I
D
I
L
ASCDH
P
N
I
V
K
L
L
D
A
F
Y
YEN
N
L
W
I
L
I
E
FCAGG
A
V
D
A
V
M
L
E
L
ERPL
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
HDN
K
I
I
H
R
DLKAG
N
I
L
F
TLDG
D
I
K
L
A
D
FGVSAKN
T
R
T
I
Q
R
R
DSFIGTPYWMA
P
E
V
V
M
CETSKDRPYDYKA
D
V
W
S
L
G
I
T
L
I
E
M
AEIEPPHHEL
N
P
M
R
V
L
L
K
I
AKSEPPTLAQPSRW
S
S
N
F
K
D
F
L
K
K
C
L
EKNVDARW
T
T
S
Q
L
LQHP
F
V
T
VDSNK
P
I
R
E
L
I
A
E
A
K
A
E
V
T
E
E
V
EDGKEE
D
E
E
EETENSLPIPASKRASSDLSIASS
E
E
D
KLSQ
N
A
C
I
L
E
S
V
S
E
K
TERSNS
E
D
K
L
N
S
K
ILNEKPTTD
E
P
E
K
A
V
E
D
I
N
E
H
I
T
D
A
Q
L
E
A
M
T
E
L
H
D
R
T
A
V
IKEN
E
R
EKRPKLENLPDTEDQ
E
T
V
DINSVSEGKEN
N
I
M
I
T
L
ETNIEHNLKS
E
E
E
K
D
Q
E
K
Q
Q
M
F
E
N
KLI
K
S
E
E
I
K
D
T
I
L
Q
T
V
D
L
V
S
QETGEKEA
N
I
Q
A
VDSEVGLT
K
E
D
T
Q
E
KLGEDDK
T
Q
K
D
VISNTSD
V
I
GTC
E
A
A
D
V
A
Q
K
VDEDSAEDTQSND
G
K
E
V
V
E
V
G
Q
K
L
I
NKPMVGPEAGGTKEV
P
I
K
E
I
V
E
M
N
E
I
EEGK
N
K
E
QAINSSEN
I
M
DINEEPGTTEGEEITESSST
E
E
M
E
V
R
S
V
VADT
D
Q
K
A
L
G
S
E
V
Q
D
A
S
K
V
T
T
Q
I
DKEKKEIPVSIKKEP
E
V
T
V
V
SQPTEPQ
P
V
L
I
P
S
I
N
INSDSGE
N
K
E
E
IGSLSKTETILPPESENPKENDNDSGTGSTADT
S
S
I
D
L
N
L
S
I
S
S
F
L
S
KTKDSG
S
I
S
L
Q
E
T
R
R
Q
K
K
T
L
K
K
T
R
K
F
I
VDG
V
E
V
S
V
T
T
S
K
I
V
TDSDS
K
T
E
E
L
R
F
L
R
R
Q
E
L
R
E
L
R
F
L
Q
K
E
E
Q
R
A
Q
Q
Q
L
N
S
K
L
Q
Q
Q
R
E
Q
I
F
R
R
F
E
Q
E
M
M
S
K
K
R
Q
Y
D
Q
E
I
E
N
L
E
K
Q
Q
K
Q
T
I
E
R
L
E
Q
E
H
T
N
R
L
R
D
E
A
K
R
IKG
E
Q
E
K
E
L
S
K
F
Q
N
M
L
K
N
R
K
K
E
V
I
N
E
V
E
K
A
P
K
E
L
R
K
E
L
M
K
R
R
K
E
E
L
A
Q
S
QH
A
Q
E
Q
E
F
V
Q
K
Q
Q
Q
E
L
D
G
S
L
K
K
I
I
Q
Q
Q
K
A
E
L
A
N
I
E
R
E
C
LN
N
K
Q
Q
L
M
R
A
R
E
A
A
I
W
E
L
E
E
R
H
L
Q
E
K
H
Q
L
L
K
Q
Q
L
K
D
Q
Y
F
M
Q
R
H
Q
L
L
K
R
H
E
K
E
T
E
Q
M
Q
R
Y
N
Q
R
L
I
E
E
L
KN
R
Q
T
Q
E
R
ARLP
K
I
Q
R
S
E
A
K
T
R
M
A
M
F
K
K
S
LRINSTATPD
Q
D
R
D
K
I
K
Q
F
A
A
Q
E
E
K
R
Q
K
N
E
R
M
A
Q
H
Q
K
H
E
N
Q
M
R
D
L
Q
L
Q
CE
A
N
V
R
E
L
H
Q
L
QNEK
C
H
L
L
V
EH
E
T
Q
K
L
K
E
L
D
E
E
H
S
Q
E
L
K
E
W
R
E
KLR
P
R
K
K
T
L
E
E
E
F
A
R
K
L
Q
EQ
E
V
F
F
K
MTGESECLNP
S
T
Q
S
R
I
S
KFYPIPSLHSTGS
21
Blastp_CBE
77.89
99%
-104
- C1 -
-
4USF
1
SLK_HUMAN
B:
[3-294]
------------------
K
Q
Y
E
H
V
T
R
D
L
N
P
E
D
F
W
E
I
I
G
E
L
G
D
G
A
F
G
K
V
Y
K
A
Q
N
K
E
T
S
V
L
A
A
A
K
V
I
D
T
K
S
E
E
E
L
E
D
Y
M
V
E
I
D
I
L
A
S
C
D
H
P
N
I
V
K
L
L
D
A
F
Y
Y
E
N
N
L
W
I
L
I
E
F
C
A
G
G
A
V
D
A
V
M
L
E
L
E
R
P
L
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
I
K
L
A
D
F
G
V
S
A
K
N
---------
F
I
G
T
P
Y
W
M
A
P
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
E
I
E
P
P
H
H
E
L
N
P
M
R
V
L
L
K
I
A
K
S
E
P
P
T
L
A
Q
P
S
R
W
S
S
N
F
K
D
F
L
K
K
C
L
E
K
N
V
D
A
R
W
T
T
S
Q
L
L
Q
H
P
F
V
T
V
D
S
N
K
P
I
R
E
L
I
A
E
A
K
A
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
69.10
96%
-103
- C1 -
-
2JFL
6
SLK_HUMAN
A:
[26-313]
--------------------
Y
E
H
V
T
R
D
L
N
P
E
D
F
W
E
I
I
G
E
L
G
D
G
A
F
G
K
V
Y
K
A
Q
N
K
E
T
S
V
L
A
A
A
K
V
I
D
T
K
S
E
E
E
L
E
D
Y
M
V
E
I
D
I
L
A
S
C
D
H
P
N
I
V
K
L
L
D
A
F
Y
Y
E
N
N
L
W
I
L
I
E
F
C
A
G
G
A
V
D
A
V
M
L
E
L
E
R
P
L
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
I
K
L
A
D
F
G
V
S
A
K
N
T
R
T
I
Q
R
R
D
S
F
I
G
T
P
Y
W
M
A
P
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
E
I
E
P
P
H
H
E
L
N
P
M
R
V
L
L
K
I
A
K
S
E
P
P
T
L
A
Q
P
S
R
W
S
S
N
F
K
D
F
L
K
K
C
L
E
K
N
V
D
A
R
W
T
T
S
Q
L
L
Q
H
P
F
V
T
V
D
S
N
K
P
I
R
E
L
I
A
E
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
67.76
97%
-98
- C1 -
-
2J51
5
SLK_HUMAN
A:
[26-313]
--------------------
Y
E
H
V
T
R
D
L
N
P
E
D
F
W
E
I
I
G
E
L
G
D
G
A
F
G
K
V
Y
K
A
Q
N
K
E
T
S
V
L
A
A
A
K
V
I
D
T
K
S
E
E
E
L
E
D
Y
M
V
E
I
D
I
L
A
S
C
D
H
P
N
I
V
K
L
L
D
A
F
Y
Y
E
N
N
L
W
I
L
I
E
F
C
A
G
G
A
V
D
A
V
M
L
E
L
E
R
P
L
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
I
K
L
A
D
F
G
V
S
A
K
N
T
R
T
I
Q
R
R
D
S
F
I
G
T
P
Y
W
M
A
P
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
E
I
E
P
P
H
H
E
L
N
P
M
R
V
L
L
K
I
A
K
S
E
P
P
T
L
A
Q
P
S
R
W
S
S
N
F
K
D
F
L
K
K
C
L
E
K
N
V
D
A
R
W
T
T
S
Q
L
L
Q
H
P
F
V
T
V
D
S
N
K
P
I
R
E
L
I
A
E
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
66.01
99%
-101
- C1 -
-
6HVD
4
SLK_HUMAN
A:
[3-293]
------------------
K
Q
Y
E
H
V
T
R
D
L
N
P
E
D
F
W
E
I
I
G
E
L
G
D
G
A
F
G
K
V
Y
K
A
Q
N
K
E
T
S
V
L
A
A
A
K
V
I
D
T
K
S
E
E
E
L
E
D
Y
M
V
E
I
D
I
L
A
S
C
D
H
P
N
I
V
K
L
L
D
A
F
Y
Y
E
N
N
L
W
I
L
I
E
F
C
A
G
G
A
V
D
A
V
M
L
E
L
E
R
P
L
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
I
K
L
A
D
F
G
V
S
A
K
N
T
R
------
S
F
I
G
T
P
Y
W
M
A
P
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
E
I
E
P
P
H
H
E
L
N
P
M
R
V
L
L
K
I
A
K
S
E
P
P
T
L
A
Q
P
S
R
W
S
S
N
F
K
D
F
L
K
K
C
L
E
K
N
V
D
A
R
W
T
T
S
Q
L
L
Q
H
P
F
V
T
V
D
S
N
K
P
I
R
E
L
I
A
E
A
K
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.14
96%
-101
* C1 *
-
2UV2
6
SLK_HUMAN
A:
[26-313]
--------------------
Y
E
H
V
T
R
D
L
N
P
E
D
F
W
E
I
I
G
E
L
G
D
--
F
G
K
V
Y
K
A
Q
N
K
E
T
S
V
L
A
A
A
K
V
I
D
T
K
S
E
E
E
L
E
D
Y
M
V
E
I
D
I
L
A
S
C
D
H
P
N
I
V
K
L
L
D
A
F
Y
Y
E
N
N
L
W
I
L
I
E
F
C
A
G
G
A
V
D
A
V
M
L
E
L
E
R
P
L
T
E
S
Q
I
Q
V
V
C
K
Q
T
L
D
A
L
N
Y
L
H
D
N
K
I
I
H
R
D
L
K
A
G
N
I
L
F
T
L
D
G
D
I
K
L
A
D
F
G
V
S
A
K
N
T
R
T
I
Q
R
R
D
S
F
I
G
T
P
Y
W
M
A
P
E
V
V
M
C
E
T
S
K
D
R
P
Y
D
Y
K
A
D
V
W
S
L
G
I
T
L
I
E
M
A
E
I
E
P
P
H
H
E
L
N
P
M
R
V
L
L
K
I
A
K
S
E
P
P
T
L
A
Q
P
S
R
W
S
S
N
F
K
D
F
L
K
K
C
L
E
K
N
V
D
A
R
W
T
T
S
Q
L
L
Q
H
P
F
V
T
V
D
S
N
K
P
I
R
E
L
I
A
E
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------