@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Screening
Virtual Screening Score
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : STK4_HUMAN: (2019-05-04 )
METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF
Atome Classification :
(3 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(pKd)
(pKd)
(Uniprot)
M
E
T
VQLRNP
P
R
R
Q
L
K
KL
D
E
D
SLTK
Q
P
E
E
V
F
D
V
L
E
K
LGEGS
Y
G
S
V
Y
K
A
I
H
KETG
Q
I
V
A
I
K
QVP
V
E
S
D
L
Q
E
I
I
K
E
I
S
I
M
Q
QCDSP
H
V
V
K
Y
Y
G
S
YFKNT
D
L
W
I
V
M
EYCGAG
S
V
S
D
I
I
R
L
RNKTL
T
E
D
E
I
A
T
I
L
Q
S
T
L
K
G
L
E
Y
L
H
F
M
R
K
I
H
R
D
IKAG
N
I
L
L
NTEGH
A
K
LADFGVA
G
Q
L
T
D
T
M
AKRNTVIGT
P
F
WM
A
P
E
V
I
Q
E
IG
Y
N
C
V
A
D
I
W
S
L
G
I
T
A
I
EMAEGKPPYADIH
P
M
R
A
I
F
M
I
PTNPPPTFRKPELWSD
N
F
T
D
F
V
K
Q
C
L
VKSP
E
Q
R
A
T
A
T
Q
L
L
Q
H
PFVRSA
K
G
V
S
I
L
R
D
L
I
N
E
A
M
D
V
K
L
K
R
Q
E
S
Q
QREVDQDDEENSEEDEMDSG
T
M
V
R
AVGDEMG
T
V
R
V
A
S
TMTDGAN
T
M
IEHDDT
L
P
S
QL
G
T
M
V
INAEDEEEEG
T
M
K
RRDETMQPAK
P
S
F
L
E
Y
F
E
Q
K
E
K
E
N
Q
I
N
S
F
G
KSVPGPLKNSSDWKIPQDG
D
Y
E
F
L
K
SW
T
V
E
D
L
Q
K
R
L
L
ALD
P
M
M
E
Q
E
I
E
E
I
R
Q
K
Y
Q
SKRQ
P
I
L
D
A
I
E
A
K
K
R
R
QQNF
4
PsiBlast_PDB
92.76
90%
-107
- C1 -
-
5DH3
7.8
-
STK3_HUMAN
A:
[21-304]
---------------------
L
T
K
Q
P
E
E
V
F
D
V
L
E
K
L
G
E
G
S
Y
G
S
V
F
K
A
I
H
K
E
S
G
Q
V
V
A
I
K
Q
V
P
V
E
S
D
L
Q
E
I
I
K
E
I
S
I
M
Q
Q
C
D
S
P
Y
V
V
K
Y
Y
G
S
Y
F
K
N
T
D
L
W
I
V
M
E
Y
C
G
A
G
S
V
S
D
I
I
R
L
R
N
K
T
L
I
E
D
E
I
A
T
I
L
K
S
T
L
K
G
L
E
Y
L
H
F
M
R
K
I
H
R
D
I
K
A
G
N
I
L
L
N
T
E
G
H
A
K
L
A
D
F
G
V
A
G
Q
L
T
D
T
M
A
K
R
N
T
V
I
G
T
P
F
W
M
A
P
E
V
I
Q
E
I
G
Y
N
C
V
A
D
I
W
S
L
G
I
T
S
I
E
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
A
I
F
M
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
S
D
D
F
T
D
F
V
K
K
C
L
V
K
N
P
E
Q
R
A
T
A
T
Q
L
L
Q
H
P
F
I
K
N
A
K
P
V
S
I
L
R
D
L
I
T
E
A
M
E
I
K
A
K
R
H
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24
Blastp_CBE
90.43
91%
-108
- C1 -
-
5DH3
7.8
-
STK3_HUMAN
B:
[20-304]
--------------------
S
L
T
K
Q
P
E
E
V
F
D
V
L
E
K
L
G
E
G
S
Y
G
S
V
F
K
A
I
H
K
E
S
G
Q
V
V
A
I
K
Q
V
P
V
E
S
D
L
Q
E
I
I
K
E
I
S
I
M
Q
Q
C
D
S
P
Y
V
V
K
Y
Y
G
S
Y
F
K
N
T
D
L
W
I
V
M
E
Y
C
G
A
G
S
V
S
D
I
I
R
L
R
N
K
T
L
I
E
D
E
I
A
T
I
L
K
S
T
L
K
G
L
E
Y
L
H
F
M
R
K
I
H
R
D
I
K
A
G
N
I
L
L
N
T
E
G
H
A
K
L
A
D
F
G
V
A
G
Q
L
T
D
T
M
A
K
R
N
T
V
I
G
T
P
F
W
M
A
P
E
V
I
Q
E
I
G
Y
N
C
V
A
D
I
W
S
L
G
I
T
S
I
E
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
A
I
F
M
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
S
D
D
F
T
D
F
V
K
K
C
L
V
K
N
P
E
Q
R
A
T
A
T
Q
L
L
Q
H
P
F
I
K
N
A
K
P
V
S
I
L
R
D
L
I
T
E
A
M
E
I
K
A
K
R
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
43.30
93%
-126
- C1 -
-
6AO5
5.1
-
STK3_HUMAN
A:
[13-287]
------------------------------
D
V
L
E
K
L
G
E
G
S
Y
G
S
V
F
K
A
I
H
-----
V
V
A
I
K
Q
-----
D
L
Q
E
I
I
K
E
I
S
I
M
Q
Q
C
D
S
P
Y
V
V
K
Y
Y
G
S
Y
F
----
L
W
I
V
M
E
Y
C
G
A
G
S
V
S
D
I
I
R
L
R
N
K
T
L
I
E
D
E
I
A
T
I
L
K
S
T
L
K
G
L
E
Y
L
H
F
M
R
K
I
H
R
N
I
K
A
G
N
I
L
L
N
T
E
G
H
A
K
L
A
D
F
G
V
A
------------
V
I
G
T
P
F
W
M
A
P
E
V
I
Q
E
I
G
Y
N
C
V
A
D
I
W
S
L
G
I
T
S
I
E
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
A
I
F
M
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
S
D
D
F
T
D
F
V
K
K
C
L
V
K
N
P
E
Q
R
A
T
A
T
Q
L
L
Q
H
P
F
I
K
N
A
K
P
V
S
I
L
R
D
L
I
T
E
A
M
E
I
K
A
K
R
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------