@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR1F2_RORb: (2019-08-19 )
MCENQLKTKADATAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNGLSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK
Atome Classification :
(7 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MCENQLKTKAD
A
T
A
Q
I
E
V
I
P
C
K
ICGDKSSG
I
H
Y
G
V
I
T
CE
G
C
K
G
F
F
R
RSQQNNASYSCPRQRNCLIDRTNR
N
R
C
Q
H
C
R
L
Q
K
C
L
A
LGMS
R
D
A
V
K
F
G
R
M
S
K
K
Q
R
D
S
L
Y
A
E
V
Q
K
H
Q
Q
R
L
Q
E
Q
R
Q
QQSG
E
A
E
A
L
A
R
V
Y
S
S
S
I
S
N
G
L
S
NLNNETSGTYAN
G
H
V
I
DLPKSEG
Y
Y
NVDSGQPSPDQSGL
D
M
T
G
I
K
Q
I
K
QEPIYDLTSVP
N
L
F
T
YSSFNNGQLAPG
I
T
M
T
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
WQTH
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
CQND
Q
I
L
L
LKSG
C
L
E
V
V
L
V
R
M
C
R
A
FNPLNN
T
V
L
F
EGKY
G
G
M
Q
M
F
K
A
LGS
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
SLQL
T
E
E
E
I
A
L
FS
S
A
V
L
ISPD
R
A
W
L
IE
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
KNHL
D
D
E
T
L
A
K
L
I
A
KIPT
I
T
A
V
C
NLH
G
E
K
L
Q
V
F
K
QS
H
P
E
I
V
N
T
L
F
P
P
L
Y
K
E
LFNPDCATGCK
3
PsiBlast_PDB
98.26
98%
-161
- C1 -
-
1NQ7
1
RORB_RAT
A:
[1-244]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
S
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
C
Q
N
D
Q
I
L
L
L
K
S
G
C
L
E
V
V
L
V
R
M
C
R
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
G
G
M
Q
M
F
K
A
L
G
S
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
S
L
Q
L
T
E
E
E
I
A
L
F
S
S
A
V
L
I
S
P
D
R
A
W
L
L
E
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
K
N
H
L
D
D
E
T
L
A
K
L
I
A
K
I
P
T
I
T
A
V
C
N
L
H
G
E
K
L
Q
V
F
K
Q
S
H
P
D
I
V
N
T
L
F
P
P
L
Y
K
E
L
F
N
--------
1
PsiBlast_PDB
97.07
98%
-157
- C1 -
-
1N4H
1
RORB_RAT
A:
[8-251]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
S
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
C
Q
N
D
Q
I
L
L
L
K
S
G
C
L
E
V
V
L
V
R
M
C
R
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
G
G
M
Q
M
F
K
A
L
G
S
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
S
L
Q
L
T
E
E
E
I
A
L
F
S
S
A
V
L
I
S
P
D
R
A
W
L
L
E
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
K
N
H
L
D
D
E
T
L
A
K
L
I
A
K
I
P
T
I
T
A
V
C
N
L
H
G
E
K
L
Q
V
F
K
Q
S
H
P
D
I
V
N
T
L
F
P
P
L
Y
K
E
L
F
N
--------
2
PsiBlast_PDB
96.33
98%
-160
- C1 -
-
1K4W
1
RORB_RAT
A:
[8-251]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
S
E
I
D
R
I
A
Q
N
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
C
A
I
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
I
T
G
F
M
E
L
C
Q
N
D
Q
I
L
L
L
K
S
G
C
L
E
V
V
L
V
R
M
C
R
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
G
G
M
Q
M
F
K
A
L
G
S
D
D
L
V
N
E
A
F
D
F
A
K
N
L
C
S
L
Q
L
T
E
E
E
I
A
L
F
S
S
A
V
L
I
S
P
D
R
A
W
L
L
E
P
R
K
V
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Q
K
N
H
L
D
D
E
T
L
A
K
L
I
A
K
I
P
T
I
T
A
V
C
N
L
H
G
E
K
L
Q
V
F
K
Q
S
H
P
D
I
V
N
T
L
F
P
P
L
Y
K
E
L
F
N
--------
4
PsiBlast_PDB
85.24
61%
-167
- C1 -
-
4S15
2
RORA_HUMAN
A:
[2-245]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
S
L
E
V
V
F
I
R
M
C
R
A
F
D
S
Q
N
N
T
V
Y
F
D
G
K
Y
A
S
P
D
V
F
K
S
L
G
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
M
H
L
T
E
D
E
I
A
L
F
S
A
F
V
L
M
S
A
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
N
H
R
E
D
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
L
H
F
P
P
L
Y
K
E
L
F
T
--------
6
PsiBlast_PDB
84.71
61%
-165
- C1 -
-
1S0X
1
A:
[18-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
S
L
E
V
V
F
I
R
M
C
R
A
F
D
S
Q
N
N
T
V
Y
F
D
G
K
Y
A
S
P
D
V
F
K
S
L
G
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
M
H
L
T
E
D
E
I
A
L
F
S
A
F
V
L
M
S
A
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
N
H
R
E
D
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
L
H
F
P
P
L
Y
K
E
L
F
---------
5
PsiBlast_PDB
84.61
61%
-166
- C1 -
-
1N83
1
A:
[18-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
S
L
E
V
V
F
I
R
M
C
R
A
F
D
S
Q
N
N
T
V
Y
F
D
G
K
Y
A
S
P
D
V
F
K
S
L
G
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
M
H
L
T
E
D
E
I
A
L
F
S
A
F
V
L
M
S
A
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
N
H
R
E
D
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
L
H
F
P
P
L
Y
K
E
L
F
---------
21
Blastp_CBE
84.23
62%
-158
- C1 -
-
4S15
2
B:
[2-247]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
A
E
L
E
H
L
A
Q
N
I
S
K
S
H
L
E
T
C
Q
Y
L
R
E
E
L
Q
Q
I
T
W
Q
T
F
L
Q
E
E
I
E
N
Y
Q
N
K
Q
R
E
V
M
W
Q
L
C
A
I
K
I
T
E
A
I
Q
Y
V
V
E
F
A
K
R
I
D
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
S
L
E
V
V
F
I
R
M
C
R
A
F
D
S
Q
N
N
T
V
Y
F
D
G
K
Y
A
S
P
D
V
F
K
S
L
G
C
E
D
F
I
S
F
V
F
E
F
G
K
S
L
C
S
M
H
L
T
E
D
E
I
A
L
F
S
A
F
V
L
M
S
A
D
R
S
W
L
Q
E
K
V
K
I
E
K
L
Q
Q
K
I
Q
L
A
L
Q
H
V
L
Q
K
N
H
R
E
D
G
I
L
T
K
L
I
C
K
V
S
T
L
R
A
L
C
G
R
H
T
E
K
L
M
A
F
K
A
I
Y
P
D
I
V
R
L
H
F
P
P
L
Y
K
E
L
F
T
S
E
------