@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR2E1_TLX: (2021-05-27 )
MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120..---.....130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240....-...250.-......260.......270.......280.......290.....--..300.......310.......320.......330.......340.......-350.......360.......370.......380...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSKPAGSTS
R
I
L
D
I
P
C
K
VCGDRSSG
K
H
Y
G
V
Y
A
CDG
C
S
G
F
F
K
R
S
IRRN
R
T
Y
V
C
KSGNQGGCPVDK
T
H
R
N
Q
C
R
A
C
R
L
K
K
C
L
E
VNMNK
D
A
V
Q
HERGPR
T
S
T
I
R
K
Q
V
A
L
Y
F
RGHKEENGAAAHFPSAA---LPA
P
A
F
F
T
A
V
T
QLEPHG
L
E
L
A
A
VSTTP
E
R
Q
T
L
V
S
LAQPTPKYPHEVNGT
P
M
Y
L
Y
E
V
A
T
E
S
V
C
E
S
A
A
R
L
L
F
M
S
I
K
WAKSVPAFSTL
S
L
Q
D
Q
L
M
L
L
E
D
A
W
R
E
L
F
V
L
G
I
A
Q
W
A
I
PVDA
N
T
L
L
A
V
S-GMNGDNT-
D
S
Q
K
L
N
K
I
I
S
E
I
Q
A
L
Q
E
V
V
A
R
F
R
Q
LRL
D
A
T
E
F
A
C
L
K
C
I
V
T
F
KAV--PTHS
G
S
E
L
R
S
F
R
N
A
A
A
I
A
A
LQ
D
E
A
Q
L
T
L
N
S
Y
I
HTRYPTQPCR
F
G
K
L
L
L
L
L
P
A
-
L
RSI
S
P
S
T
I
E
E
V
F
F
K
K
TIGNV
P
I
T
R
L
L
S
D
M
YKSSDI
2
PsiBlast_PDB
65.24
34%
-53
- C1 -
-
4NQA
1
RXRA_HUMAN
A:
[31-359]
--------
A
S
F
T
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
--
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
--------------
R
G
------------
S
S
A
NED
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
--------
K
T
E
T
Y
-
E
A
N
M
G
L
N
P
S
S
P
N
D
P
--------------
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
----
4
PsiBlast_PDB
65.09
33%
-76
- C1 -
-
3DZU
1
RXRA_HUMAN
A:
[137-460]
------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
--
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
--------------
R
---------------
A
NED
M
P
V
E
R
I
L
E
A
E
L
A
-----------------------------
D
P
--------------
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
---------
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
-----
5
PsiBlast_PDB
64.91
33%
-73
- C1 -
-
3E00
1
RXRA_HUMAN
A:
[137-460]
------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
--
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
--------------
R
---------------
A
NED
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------------------------------
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
---------
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
-----
3
PsiBlast_PDB
61.02
34%
-71
- C1 -
-
5UAN
1
RXRA_HUMAN
A:
[36-360]
-------------
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
----------
D
--
C
L
I
D
K
R
Q
R
N
-
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
-------------------------------
A
NED
M
P
V
E
R
I
L
E
A
E
L
A
V
E
----------------------------
P
--------------
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
7
PsiBlast_PDB
56.07
34%
-79
- C1 -
-
4IQR
1
HNF4A_HUMAN
A:
[21-334]
---------------
C
A
I
C
G
D
R
A
T
G
K
H
Y
G
A
S
S
C
D
G
C
K
G
F
F
R
R
S
V
R
K
N
H
M
Y
S
C
R
F
S
R
Q
--
C
V
V
D
K
D
K
R
N
Q
C
R
Y
C
R
L
K
K
C
F
R
A
G
M
K
K
E
A
V
Q
N
E
------------------------------------------
I
N
A
L
L
Q
A
E
V
----
L
S
R
Q
I
T
S
P
---------------
V
S
G
I
N
G
D
I
R
A
K
K
I
A
S
I
A
D
V
C
E
S
M
K
E
Q
L
L
V
L
V
E
W
A
K
Y
I
P
A
F
C
E
L
P
L
D
D
Q
V
A
L
L
R
A
H
A
G
E
H
L
L
L
G
A
T
K
R
S
M
V
F
K
D
V
L
L
L
G
N
D
-
Y
I
V
P
R
H
C
P
E
L
A
E
M
S
R
V
--
S
I
R
I
L
D
E
L
V
L
P
F
Q
E
L
Q
I
D
D
N
E
Y
A
Y
L
K
A
I
I
F
F
D
----
P
D
A
K
G
-----
L
S
D
P
G
K
I
K
R
L
R
S
Q
V
Q
V
S
L
E
D
Y
I
N
D
R
Q
Y
D
S
R
G
R
F
G
E
L
L
L
L
L
P
T
-
L
Q
S
I
T
W
Q
M
I
E
Q
I
Q
F
I
K
L
F
G
M
A
K
I
D
N
L
L
Q
E
M
------
1
PsiBlast_PDB
52.08
98%
-152
- C1 -
-
4XAJ
-
MALE_ECO57 (first)
A:
[375-576]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
S
V
C
E
S
A
A
R
L
L
F
M
S
I
K
W
A
K
S
V
P
A
F
S
T
L
S
L
Q
D
Q
L
M
L
L
E
D
A
W
R
E
L
F
V
L
G
I
A
Q
W
A
I
P
V
D
A
N
T
L
L
A
V
S
-
G
M
N
G
D
N
T
-
D
S
Q
R
L
T
L
I
I
S
E
I
Q
A
L
Q
E
V
V
A
R
F
R
Q
L
R
L
D
A
T
E
F
A
C
L
K
C
I
V
T
F
K
A
V
--
P
------
L
R
S
F
R
N
A
A
A
I
A
A
L
Q
D
E
A
Q
L
T
L
N
S
Y
I
H
T
R
Y
P
T
Q
P
V
R
F
G
K
L
L
L
L
L
P
A
-
L
R
S
I
S
P
S
T
I
E
E
V
F
F
K
K
T
I
G
N
V
P
I
T
R
L
L
S
D
M
Y
K
S
S
--
8
PsiBlast_PDB
36.33
38%
-190
- C1 -
-
3CJW
-
COT2_HUMAN
A:
[207-402]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
I
E
N
I
C
E
L
A
A
R
M
L
F
S
A
V
E
W
A
R
N
I
P
F
F
P
D
L
Q
I
T
D
Q
V
A
L
L
R
L
T
W
S
E
L
F
V
L
N
A
A
Q
C
S
M
P
L
H
V
A
P
-------------------
V
A
F
M
D
H
I
R
I
F
Q
E
Q
V
E
K
L
K
A
L
H
V
D
S
A
E
Y
S
C
L
K
A
I
V
L
F
T
---------
S
D
A
C
G
L
S
D
V
A
H
V
E
S
L
Q
E
K
S
Q
C
A
L
E
E
Y
V
R
S
Q
Y
P
N
Q
P
T
R
F
G
K
L
L
L
R
L
P
S
-
L
R
T
V
S
S
S
V
I
E
Q
L
F
F
V
R
L
V
G
K
T
P
I
E
T
L
I
R
D
M
L
L
S
---
6
PsiBlast_PDB
33.78
47%
-183
- C1 -
-
4LOG
-
MALE_ECOLI (first)
A:
[1218-1410]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
I
H
E
T
S
A
R
L
L
F
M
A
V
K
W
A
K
N
L
P
V
F
S
S
L
P
F
R
D
Q
V
I
L
L
E
E
A
W
S
E
L
F
L
L
G
A
I
Q
W
S
L
P
L
D
S
C
P
L
L
A
P
P
-------------
L
T
L
A
S
M
E
T
R
V
L
Q
E
T
I
S
R
F
R
A
L
A
V
D
P
T
E
F
A
C
M
K
A
L
V
L
F
K
---------
P
E
T
R
G
L
K
D
P
E
H
V
E
A
L
Q
D
Q
S
Q
V
M
L
S
Q
H
S
K
A
H
H
P
S
Q
P
V
R
F
G
K
L
L
L
L
L
P
S
-
L
R
F
I
T
A
E
R
I
E
L
L
F
F
R
K
T
I
G
N
T
P
M
E
K
L
L
S
D
M
F
K
N
---
19
PsiBlast_PDB
18.49
36%
-86
- C1 -
-
6STI
1
RXRA_HUMAN
A:
[49-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
14
PsiBlast_PDB
18.12
36%
-83
- C1 -
-
3E94
1
RXRA_HUMAN
A:
[49-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
9
PsiBlast_PDB
17.98
42%
-95
- C1 -
-
4XAI
-
MALE_ECO57
A:
[375-573]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
C
E
S
A
A
Q
L
I
F
M
N
V
Q
W
V
R
S
I
P
A
F
T
C
L
P
L
S
D
Q
L
L
L
L
E
E
S
W
L
D
L
F
V
L
G
A
A
Q
F
L
P
L
M
D
F
S
V
L
V
E
A
C
-
G
V
L
--
Q
Q
-
E
P
H
R
R
D
A
F
L
K
E
V
A
D
F
Q
E
T
L
K
K
I
S
Q
F
Q
L
D
A
H
E
F
A
C
L
R
A
I
V
L
F
K
T
S
FE-------
E
K
T
T
T
E
S
A
K
I
S
V
I
Q
D
D
A
Q
M
R
L
N
K
H
V
T
T
T
Y
P
K
Q
P
L
R
F
G
K
I
L
L
L
V
S
S
T
F
R
T
I
S
G
R
T
I
E
D
L
F
F
K
K
V
I
R
D
T
P
I
V
A
I
I
S
N
M
Y
-----
11
PsiBlast_PDB
17.90
36%
-84
- C1 -
-
4OC7
1
RXRA_HUMAN
A:
[59-249]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
15
PsiBlast_PDB
17.24
36%
-90
- C1 -
-
3KWY
1
RXRA_HUMAN
A:
[49-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
--
I
D
T
F
L
M
E
M
L
E
A
---
10
PsiBlast_PDB
13.60
36%
-93
- C1 -
-
6HN6
3
RXRA_HUMAN
A:
[87-277]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
17
PsiBlast_PDB
11.57
36%
-86
- C1 -
-
4N8R
1
RXRA_HUMAN
A:
[49-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
20
PsiBlast_PDB
11.51
36%
-89
- C1 -
-
5ZQU
2
RXRA_HUMAN
A:
[48-238]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
18
PsiBlast_PDB
10.53
36%
-88
- C1 -
-
5TBP
4
RXRA_HUMAN
A:
[49-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
16
PsiBlast_PDB
8.92
36%
-79
* C1 *
-
4N5G
1
RXRA_HUMAN
A:
[49-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
13
PsiBlast_PDB
1.18
36%
0
- C- -
-
4J5X
-
D:
[41-248]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---
12
PsiBlast_PDB
1.18
36%
0
- C- -
-
4J5W
-
?
C:
[41-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
-
H
S
A
G
V
G
A
I
F
D
R
V
--
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
----
P
D
S
K
G
-----
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
-
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
---