@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR6A1_GCN1: (2021-05-27 )
MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.....-..140.......150---.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGF
C
Q
D
E
L
AELDP
G
T
I
SVSDDRAEQ
R
T
C
L
I
CGDRATG
L
H
Y
G
I
I
SCE
G
C
K
G
F
F
K
R
S
I
C
N
K
R
V
Y
RCSRDK
N
C
V
M
S
R
K
QR
N
R
C
Q
Y
C
R
L
L
K
C
L
Q
MGM
N
R
K
A
I
REDGMPG-GRNKSIG
P
V
QI
S
E
E
E
---
I
E
R
I
MSG
Q
E
F
E
E
E
A
NHWSNHGDSDHSSPGNRASESNQPSPGSTLSSS
R
S
V
E
L
N
G
F
M
A
F
R
E
Q
YMGMSVPP
H
Y
Q
Y
I
P
H
L
FSYSGHSPLL
P
Q
Q
A
RSLD
P
Q
S
Y
S
L
I
H
Q
L
L
S
AEDLEPLGT
P
M
L
IEDGYA
V
T
Q
A
E
L
F
A
L
L
C
R
L
A
D
E
L
L
F
R
Q
I
A
W
I
K
KL
P
F
F
C
E
L
SIK
D
Y
T
C
L
L
S
S
T
W
Q
E
L
I
L
L
S
S
L
T
V
Y
S
K
Q
I
F
G
E
L
A
D
V
TAKYSP
S
D
E
E
L
H
R
FSDE
G
M
E
V
I
E
R
L
I
Y
L
Y
H
K
F
H
Q
L
K
VSN
E
E
Y
A
C
M
K
A
I
N
F
L
N
Q
D
I
R
GL
T
S
A
S
Q
L
E
Q
L
N
K
R
Y
W
Y
I
CQDFTEYKYTHQPNRF
P
D
L
M
M
C
L
P
E
I
R
Y
I
A
G
K
MVNV
P
L
E
Q
L
P
L
L
F
K
V
V
L
H
S
C
K
T
SVGKE
1
PsiBlast_PDB
88.46
98%
-162
- C1 -
-
5KRB
-
NR6A1_MOUSE
B:
[1-74]
--------------------------------------------------------
Q
R
T
C
L
I
C
G
D
R
A
T
G
L
H
Y
G
I
I
S
C
E
G
C
K
G
F
F
K
R
S
I
S
N
K
R
V
Y
R
C
S
R
D
K
N
C
V
M
S
R
K
Q
R
N
R
C
Q
Y
C
R
L
L
K
C
L
Q
M
G
M
N
R
K
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
79.30
48%
-140
- C1 -
-
5L0M
-
NR5A2_HUMAN
A:
[8-96]
--------------------------------------------------------
E
E
L
C
P
V
C
G
D
K
V
S
G
Y
H
Y
G
L
L
T
C
E
S
C
K
G
F
F
K
R
T
V
Q
N
N
K
R
Y
T
C
I
E
N
Q
N
C
Q
I
D
K
T
Q
R
K
R
C
P
Y
C
R
F
Q
K
C
L
S
V
G
M
K
L
E
A
V
R
A
D
R
M
R
G
-
G
R
N
K
-
F
G
P
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
76.73
48%
-138
- C1 -
-
2A66
-
NR5A2_HUMAN
A:
[10-97]
---------------------------------------------------------
E
L
C
P
V
C
G
D
K
V
S
G
Y
H
Y
G
L
L
T
C
E
S
C
K
G
F
F
K
R
T
V
Q
N
N
K
R
Y
T
C
I
E
N
Q
N
C
Q
I
D
K
T
Q
R
K
R
C
P
Y
C
R
F
Q
K
C
L
S
V
G
M
K
L
E
A
V
R
A
D
R
M
R
G
-
G
R
N
K
-
F
G
P
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
75.19
48%
-133
- C1 -
-
3DZU
-
RXRA_HUMAN
A:
[137-402]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
R
G
K
D
R
N
---------
E
N
E
---
V
E
S
T
S
S
A
N
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
71.64
48%
-123
- C1 -
-
3E00
-
RXRA_HUMAN
A:
[137-276]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
R
G
K
D
R
N
---------
E
N
E
---
V
E
S
T
S
S
A
N
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
64.81
47%
-122
- C1 -
-
4NQA
-
RXRA_HUMAN
A:
[35-143]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
R
G
-----------
S
S
A
N
E
DMP
V
E
R
I
L
E
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
63.92
54%
-148
- C1 -
-
4CN2
1
RXRA_HUMAN
C:
[7-85]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
62.36
55%
-146
- C1 -
-
4CN3
-
?
D:
[7-84]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
D
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
61.00
54%
-139
- C1 -
-
4CN5
-
?
A:
[7-84]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
60.51
54%
-133
- C1 -
-
6FBQ
-
?
A:
[7-84]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
58.40
58%
-153
* C1 *
-
4UMM
-
?
A:
[4-77]
-----------------------------------------------------------
C
S
I
C
G
D
R
A
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
A
C
R
E
E
R
N
C
I
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
C
G
M
K
R
E
A
V
Q
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
57.24
54%
-142
- C1 -
-
6FBR
-
?
A:
[7-83]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
56.62
55%
-115
- C1 -
-
1BY4
-
RXRA_HUMAN
A:
[5-81]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
54.89
54%
-135
- C1 -
-
4CN7
-
?
A:
[7-79]
--------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
54.04
56%
-137
- C1 -
-
1R0N
-
A:
[4-77]
---------------------------------------------------------
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
53.83
52%
-152
- C1 -
-
1DSZ
-
A:
[6-80]
----------------------------------------------------------
P
C
F
V
C
Q
D
K
S
S
G
Y
H
Y
G
V
S
A
C
E
G
C
K
G
F
F
R
R
S
I
Q
K
N
M
V
Y
T
C
H
R
D
K
N
C
I
I
N
K
V
T
R
N
R
C
Q
Y
C
R
L
Q
K
C
F
E
V
G
M
S
K
E
S
V
R
N
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
50.48
48%
-153
- C1 -
-
1YNW
-
B:
[5-77]
----------------------------------------------------------
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
47.65
54%
-128
- C1 -
-
1HRA
-
A:
[6-79]
---------------------------------------------------------
K
P
C
F
V
C
Q
D
K
S
S
G
Y
H
Y
G
V
S
A
C
E
G
C
K
G
F
F
R
R
S
I
Q
K
N
M
I
Y
T
C
H
R
D
K
N
C
V
I
N
K
V
T
R
N
R
C
Q
Y
C
R
L
Q
K
C
F
E
V
G
M
S
K
E
S
V
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
10.66
56%
-17
- C1 -
-
6FX0
1
RARG_HUMAN
A:
[198-397]
---------------------------------------------------------
K
P
C
F
V
C
N
D
K
S
S
G
Y
H
Y
G
V
S
S
C
E
G
C
K
G
F
F
R
R
S
I
Q
K
N
M
V
Y
T
C
H
R
D
K
N
C
I
I
N
K
V
T
R
N
R
C
Q
Y
C
R
L
Q
K
C
F
E
V
G
M
S
K
E
A
V
R
N
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
3.42
47%
0
- C- -
-
5UAN
-
A:
[36-162]
---------------------------------------------------------
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
----------
D
C
L
I
D
K
R
Q
R
N
-
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
----------------
A
N
E
DMP
V
E
R
I
L
E
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------