@TOME V3
(Feb 2022)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR4A2_NURR1: (2019-04-20 )
MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
Atome Classification :
(9 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFL
T
P
E
F
V
K
F
SMDLTN
T
E
I
T
A
T
TSLP
S
F
S
T
F
M
DNYSTGYDVKPP
C
L
Y
QMPLSGQQS
S
I
K
V
E
D
I
Q
MHN
Y
Q
Q
HSHLPP
Q
S
EEMMPHS
G
S
V
Y
Y
KPSSPPTPTTPG
F
Q
V
QHSPMWDDPG
S
L
H
N
F
H
Q
N
Y
V
A
T
T
H
M
I
E
Q
RKT
P
V
S
R
L
S
L
FSFKQSPPGTPVS
S
C
Q
M
R
FDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIG
H
A
S
Q
L
L
DTQVPSPPSRGSPSNE
G
L
C
A
VCGDN
A
A
C
Q
HYGVRT
C
E
G
C
K
G
F
F
K
R
T
V
QKNA
K
Y
V
C
L
ANKNCPV
D
K
R
R
R
N
R
C
Q
Y
C
R
F
Q
K
C
L
A
V
G
M
V
K
E
V
V
R
TDSLKGRRGRLPSKPKSPQEPSPPSP
P
V
S
L
I
S
A
L
V
R
A
HVDSNPAMTSLD
Y
S
RFQANPDYQMSGD
D
T
Q
H
I
Q
Q
F
Y
D
L
L
TG
S
M
E
I
I
R
G
W
A
E
KIPGFADLPKA
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
YRSNPVE
G
K
L
I
F
CN
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
SNLQN
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
RHGLKE
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
HVTFNNGGLNR
P
N
Y
L
S
K
L
L
GKL
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
DLVP
P
P
A
I
I
D
K
L
F
L
DTLPF
2
PsiBlast_PDB
78.67
100%
-172
- C1 -
-
5Y41
3
NR4A2_HUMAN
A:
[35-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
P
D
-----
D
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
N
G
G
L
N
R
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
25
Blastp_CBE
75.79
100%
-174
- C1 -
-
5Y41
2
B:
[33-271]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
V
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
P
-------
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
N
G
G
L
N
R
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
1
PsiBlast_PDB
70.26
100%
-162
- C1 -
-
6DDA
1
?
B:
[37-272]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
P
D
Y
Q
M
S
G
D
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
N
G
G
L
N
R
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
3
PsiBlast_PDB
70.04
100%
-184
- C1 -
-
5YD6
1
?
A:
[35-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
P
------
D
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
-------
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
22
Blastp_CBE
67.05
100%
-177
- C1 -
-
5YD6
1
?
D:
[33-271]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
V
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
--------
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
N
-----
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
24
Blastp_CBE
65.39
100%
-185
- C1 -
-
5YD6
1
?
B:
[35-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
P
------
D
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
N
------
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
23
Blastp_CBE
63.20
100%
-172
- C1 -
-
5YD6
1
?
C:
[33-271]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
V
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
--------
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
N
-----
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
21
Blastp_CBE
62.10
100%
-173
- C1 -
-
6DDA
1
?
C:
[37-272]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
I
S
A
L
V
R
A
H
V
D
S
N
P
A
M
T
S
L
D
Y
S
R
F
Q
A
N
P
------
D
D
T
Q
H
I
Q
Q
F
Y
D
L
L
T
G
S
M
E
I
I
R
G
W
A
E
K
I
P
G
F
A
D
L
P
K
A
D
Q
D
L
L
F
E
S
A
F
L
E
L
F
V
L
R
L
A
Y
R
S
N
P
V
E
G
K
L
I
F
C
N
G
V
V
L
H
R
L
Q
C
V
R
G
F
G
E
W
I
D
S
I
V
E
F
S
S
N
L
Q
N
M
N
I
D
I
S
A
F
S
C
I
A
A
L
A
M
V
T
E
R
H
G
L
K
E
P
K
R
V
E
E
L
Q
N
K
I
V
N
C
L
K
D
H
V
T
F
N
-----
R
P
N
Y
L
S
K
L
L
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
R
I
F
Y
L
K
L
E
D
L
V
P
P
P
A
I
I
D
K
L
F
L
D
T
L
P
F
26
Blastp_CBE
60.87
99%
-169
* C1 *
-
6DDA
1
?
A:
[37-272]
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