@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR1A1_THRa: (2019-08-14 )
MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVCEDLAGNAASP
Atome Classification :
(8 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MEQKPSKVECGSDPEENSARSPDGKRKRKNGQ
C
S
L
KTSMSGYI
P
S
Y
LDKDE
Q
C
V
V
CGDKAT
G
Y
H
Y
R
C
I
T
C
E
G
C
K
G
F
F
R
R
T
I
Q
K
NLHP
T
Y
SCKYDS
C
C
V
I
D
K
I
T
R
N
Q
C
Q
L
C
R
F
K
K
C
I
A
V
G
M
A
M
D
L
V
LDD
S
K
R
V
A
K
R
K
L
I
E
Q
N
R
E
R
R
R
K
E
E
M
I
R
S
L
Q
QRPEPTPEEW
D
L
I
H
I
A
TEAHRSTNAQG
S
H
W
K
Q
R
R
KFL
P
D
DIGQSPIVSMPDGDKV
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
KLP
M
F
SELPCED
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
YDPES
D
T
L
T
LSG
E
M
A
V
K
R
E
Q
LKNGG
L
G
V
V
S
D
A
I
F
E
L
G
K
SLSAFNLD
D
T
E
V
A
L
L
Q
A
V
L
L
MSTDRS
G
L
L
C
V
D
K
IEKSQ
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
KHNI
P
H
F
W
P
K
L
L
M
K
E
R
E
V
Q
S
S
I
LYKGAAAEGRPGGSLGVHPEG
Q
Q
L
L
G
M
HVVQGP
Q
V
R
Q
L
E
Q
Q
LGEAGSLQGPVLQHQSPK
S
P
Q
Q
R
L
L
E
L
L
H
RSGI
L
H
A
R
AVCGEDDSSEADSPSSSEE
E
P
E
V
C
E
D
L
AGNAASP
1
PsiBlast_PDB
61.41
100%
-112
- C1 -
-
1NAV
1
THA_HUMAN
A:
[3-225]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
-----
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
-----
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
C
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
61.39
99%
-98
- C1 -
-
3ILZ
1
THA_HUMAN
A:
[5-224]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
L
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
54.57
99%
-94
- C1 -
-
4LNW
2
THA_HUMAN
A:
[5-223]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
L
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
53.85
99%
-94
- C1 -
-
4LNX
2
THA_HUMAN
A:
[5-223]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
L
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
52.90
99%
-98
- C1 -
-
2H77
1
THA_HUMAN
A:
[11-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
C
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
51.67
99%
-96
- C1 -
-
2H79
1
THA_HUMAN
A:
[7-223]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
L
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.38
99%
-96
- C1 -
-
3JZB
1
THA_HUMAN
A:
[5-223]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
L
L
K
G
C
C
M
E
I
M
S
L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
S
G
E
M
A
V
K
R
E
Q
L
K
N
G
G
L
G
V
V
S
D
A
I
F
E
L
G
K
S
L
S
A
F
N
L
D
D
T
E
V
A
L
L
Q
A
V
L
L
M
S
T
D
R
S
G
L
L
L
V
D
K
I
E
K
S
Q
E
A
Y
L
L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
48.51
99%
-94
- C1 -
-
3HZF
1
THA_HUMAN
A:
[7-225]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
E
M
I
R
S
L
Q
Q
R
P
E
P
T
P
E
E
W
D
L
I
H
I
A
T
E
A
H
R
S
T
N
A
Q
G
S
H
W
K
Q
R
R
K
F
L
P
D
D
I
G
Q
S
P
I
V
S
M
P
D
G
D
K
V
D
L
E
A
F
S
E
F
T
K
I
I
T
P
A
I
T
R
V
V
D
F
A
K
K
L
P
M
F
S
E
L
P
C
E
D
Q
I
I
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K
G
C
C
M
E
I
M
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L
R
A
A
V
R
Y
D
P
E
S
D
T
L
T
L
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G
E
M
A
V
K
R
E
Q
L
K
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G
G
L
G
V
V
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D
A
I
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G
L
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E
A
Y
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L
A
F
E
H
Y
V
N
H
R
K
H
N
I
P
H
F
W
P
K
L
L
M
K
------------------------------------------------------------------------------------------------------------------------