@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR3B1_ERRa: (2021-05-27 )
MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSSQ
V
V
GI
E
P
L
Y
I
KAEPASPDSPKGSSETETEP
P
V
A
LAPGPAPTRCLPGHKEEEDGEGAGPGEQGG
G
K
L
V
L
S
SL
P
K
R
L
C
L
V
C
GDVASGYHYGVA
S
C
E
A
C
K
A
F
F
K
R
TIQG
S
I
E
YSCPASN
E
C
E
I
T
K
R
R
R
K
A
C
Q
A
C
R
F
T
K
C
L
R
V
G
M
L
K
EGVR
L
D
R
VRG
G
R
Q
K
YKRRPEVDPLPFPGPFPAG
P
L
AVAGGPRKTAA
P
V
N
A
L
V
S
H
L
L
V
V
E
P
E
K
LYAMPDPAGPDGH
L
P
A
V
A
T
L
C
D
L
FDR
E
I
V
V
T
I
S
W
A
KSIPGFSSL
S
L
S
D
Q
M
S
V
L
Q
S
V
W
M
E
V
L
V
L
G
V
A
QRSLP
L
Q
D
E
L
A
F
A
E
D
LVLDEEGARAAG
L
G
E
L
G
A
A
L
L
Q
L
V
R
R
L
Q
A
L
RLE
R
E
E
Y
V
L
L
K
A
L
ALANSD
S
V
H
IE
D
A
E
A
V
E
Q
L
R
E
A
L
H
E
A
L
L
E
Y
EAGRAGPGG
G
A
E
R
RRA
G
R
L
L
L
T
L
P
L
L
R
Q
T
A
G
K
V
L
A
H
F
YG
V
K
LEGKV
P
M
H
K
L
F
L
E
M
L
E
A
MMD
1
PsiBlast_PDB
63.28
100%
-152
- C1 -
-
3K6P
1
ERR1_HUMAN
A:
[18-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
N
A
L
V
S
H
L
L
V
V
E
P
E
K
L
Y
A
M
P
-------
H
L
P
A
V
A
T
L
C
D
L
F
D
R
E
I
V
V
T
I
S
W
A
K
S
I
P
G
F
S
S
L
S
L
S
D
Q
M
S
V
L
Q
S
V
W
M
E
V
L
V
L
G
V
A
Q
R
S
L
P
L
Q
D
E
L
A
F
A
E
D
L
V
L
D
E
E
G
A
R
A
A
G
L
G
E
L
G
A
A
L
L
Q
L
V
R
R
L
Q
A
L
R
L
E
R
E
E
Y
V
L
L
K
A
L
A
L
A
N
S
D
S
V
H
I
E
D
A
E
A
V
E
Q
L
R
E
A
L
H
E
A
L
L
E
Y
E
A
G
R
----
G
G
A
E
-
R
R
A
G
R
L
L
L
T
L
P
L
L
R
Q
T
A
G
K
V
L
A
H
F
Y
G
V
-
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
M
M
-
2
PsiBlast_PDB
53.84
100%
-167
- C1 -
-
1XB7
-
ERR1_HUMAN
A:
[17-244]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
N
A
L
V
S
H
L
L
V
V
E
P
E
K
L
Y
A
M
-----------
A
V
A
T
L
C
D
L
F
D
R
E
I
V
V
T
I
S
W
A
K
S
I
P
G
F
S
S
L
S
L
S
D
Q
M
S
V
L
Q
S
V
W
M
E
V
L
V
L
G
V
A
Q
R
S
L
P
L
Q
D
E
L
A
F
A
E
D
L
V
L
D
E
E
G
A
R
A
A
G
L
G
E
L
G
A
A
L
L
Q
L
V
R
R
L
Q
A
L
R
L
E
R
E
E
Y
V
L
L
K
A
L
A
L
A
N
S
D
S
V
H
I
E
D
A
E
A
V
E
Q
L
R
E
A
L
H
E
A
L
L
E
Y
E
A
G
---------
R
R
R
A
G
R
L
L
L
T
L
P
L
L
R
Q
T
A
G
K
V
L
A
H
F
Y
G
V
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
4
PsiBlast_PDB
51.78
95%
-165
- C1 -
-
3D24
-
ERR1_HUMAN
A:
[24-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
A
L
V
S
H
L
L
V
V
E
P
E
K
L
Y
A
M
----------
P
A
V
A
T
L
C
D
L
F
D
R
E
I
V
V
T
I
S
W
A
K
S
I
P
G
F
S
S
L
S
L
S
D
Q
M
S
V
L
Q
S
V
W
M
E
V
L
V
L
G
V
A
Q
R
S
L
P
L
Q
D
E
L
A
F
A
E
D
L
V
L
D
E
E
G
A
R
A
A
G
L
G
E
L
G
A
A
L
L
Q
L
V
R
R
L
Q
A
L
R
L
E
R
E
E
Y
V
L
L
K
A
L
A
L
A
N
S
D
S
V
H
I
E
D
A
E
A
V
E
Q
L
R
E
A
L
H
E
A
L
L
E
Y
E
A
G
--------
E
R
R
R
A
G
R
L
L
L
T
L
P
L
L
R
Q
T
A
G
K
V
L
A
H
F
Y
G
V
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
19
PsiBlast_PDB
50.79
59%
-137
* C1 *
-
6I65
1
ERR3_HUMAN
A:
[17-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
8
PsiBlast_PDB
49.46
62%
-139
- C1 -
-
2GP7
-
ERR3_HUMAN
A:
[7-228]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
14
PsiBlast_PDB
46.47
62%
-136
- C1 -
-
2EWP
1
ERR3_HUMAN
A:
[1-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
10
PsiBlast_PDB
46.26
62%
-135
- C1 -
-
2GPP
1
ERR3_HUMAN
A:
[5-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
15
PsiBlast_PDB
46.13
62%
-133
- C1 -
-
6I62
1
ERR3_HUMAN
A:
[13-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
16
PsiBlast_PDB
45.10
62%
-139
- C1 -
-
6I63
1
ERR3_HUMAN
A:
[13-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
7
PsiBlast_PDB
44.95
62%
-143
- C1 -
-
1KV6
-
ERR3_HUMAN
A:
[7-228]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
20
PsiBlast_PDB
43.83
59%
-135
- C1 -
-
6I66
3
ERR3_HUMAN
A:
[17-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
18
PsiBlast_PDB
42.88
59%
-134
- C1 -
-
6I64
4
ERR3_HUMAN
A:
[17-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
17
PsiBlast_PDB
39.00
59%
-132
- C1 -
-
6I61
7
ERR3_HUMAN
A:
[17-239]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
9
PsiBlast_PDB
38.94
62%
-135
- C1 -
-
2GPO
-
A:
[7-228]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
---
11
PsiBlast_PDB
38.46
62%
-138
- C1 -
-
2GPU
1
A:
[6-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
----
5
PsiBlast_PDB
36.49
62%
-139
- C1 -
-
5YSO
1
ERR3_HUMAN
A:
[14-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
----
22
Blastp_CBE
36.15
99%
-149
- C1 -
-
2PJL
1
ERR1_HUMAN
B:
[17-245]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
N
A
L
V
S
H
L
L
V
V
E
P
E
K
L
Y
A
M
---------
L
P
A
V
A
T
L
S
D
L
F
D
R
E
I
V
V
T
I
S
W
A
K
S
I
P
G
F
S
S
L
S
L
S
D
Q
M
S
V
L
Q
S
V
W
M
E
V
L
V
L
G
V
A
Q
R
S
L
P
L
Q
D
E
L
A
F
A
E
D
L
V
L
D
E
E
G
A
R
A
A
G
L
G
E
L
G
A
A
L
L
Q
L
V
R
R
L
Q
A
L
R
L
E
R
E
E
Y
V
L
L
K
A
L
A
L
A
N
S
D
S
V
H
I
E
D
A
E
A
V
E
Q
L
R
E
A
L
H
E
A
L
L
E
Y
E
A
G
---------
R
R
R
A
G
R
L
L
L
T
L
P
L
L
R
Q
T
A
G
K
V
L
A
H
F
Y
G
V
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
M
--
3
PsiBlast_PDB
34.18
99%
-151
- C1 -
-
2PJL
1
ERR1_HUMAN
A:
[17-245]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
N
A
L
V
S
H
L
L
V
V
E
P
E
K
L
Y
A
M
---------
L
P
A
V
A
T
L
S
D
L
F
D
R
E
I
V
V
T
I
S
W
A
K
S
I
P
G
F
S
S
L
S
L
S
D
Q
M
S
V
L
Q
S
V
W
M
E
V
L
V
L
G
V
A
Q
R
S
L
P
L
Q
D
E
L
A
F
A
E
D
L
V
L
D
E
E
G
A
R
A
A
G
L
G
E
L
G
A
A
L
L
Q
L
V
R
R
L
Q
A
L
R
L
E
R
E
E
Y
V
L
L
K
A
L
A
L
A
N
S
D
S
V
H
I
E
D
A
E
A
V
E
Q
L
R
E
A
L
H
E
A
L
L
E
Y
E
A
G
---------
R
R
R
A
G
R
L
L
L
T
L
P
L
L
R
Q
T
A
G
K
V
L
A
H
F
Y
G
V
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
A
M
--
6
PsiBlast_PDB
26.76
62%
-140
- C1 -
-
6A6K
1
ERR3_HUMAN
A:
[15-235]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
----
12
PsiBlast_PDB
25.39
62%
-125
- C1 -
-
2GPV
1
ERR3_HUMAN
A:
[5-227]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
N
K
I
V
S
H
L
L
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
E
L
V
V
I
I
G
W
A
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
S
L
L
Q
S
A
W
M
E
I
L
I
L
G
V
V
Y
R
S
L
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
L
N
N
A
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
F
V
T
L
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
A
V
Q
K
L
Q
D
V
L
H
E
A
L
Q
D
Y
E
A
G
Q
----
H
M
E
D
P
R
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
V
P
M
H
K
L
F
L
E
M
L
E
----
13
PsiBlast_PDB
15.71
62%
-122
- C1 -
-
1S9P
1
ERR3_MOUSE
A:
[2-216]
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