@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : BCR_HUMAN: (2020-09-05 )
MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV
Atome Classification :
(23 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......--490.......500.......510.......520........530.----......540.......550.......560.......570-------.--.--.--.....580..------..------.------..590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700-------------.-------------------------.-----------------------..------------------...710-......-.-720.......730.......740..-------.-------....750.------......760.......770.......780.......790.......800.......810.......820.......830.....----..---840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110........-1120........1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230.......1240......1250......1260......1270
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MVDPV
G
F
A
E
A
W
K
AQFPDSEPP
R
M
E
L
R
S
VG
D
I
E
Q
E
L
E
R
C
K
A
S
I
R
R
L
E
Q
E
V
N
Q
E
R
F
R
M
I
Y
L
Q
T
L
L
A
K
E
K
K
S
Y
D
R
Q
R
WGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGP
P
A
S
V
A
A
L
R
S
N
F
E
R
I
R
KGHGQPGADAEK
P
F
Y
V
N
V
E
F
HHERG
L
V
K
V
N
D
K
E
V
S
D
R
I
S
S
L
G
S
Q
A
M
Q
M
E
R
K
K
SQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAEL
N
P
R
F
L
KDNLIDANGGSRPPWPPLEYQPYQ
S
I
Y
VGGMMEGEGKG
P
L
LRSQST
S
E
Q
E
K
RLTWPRRSYSPR
S
F
E
DCGGGYTPDCSSNENLTSS
E
E
DFSSGQSSRVSPSP
T
T
Y
R
M
F
RDKSRSPSQNSQQSFDSSSPPT
P
Q
C
H
K
RHRHC
P
V
V
V
S
E
A
T
I
V
G
V
RKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAA
D
R
A
E
E
Q
R
R
HQDGLPYIDDSPSSSPHLSSKGRG
S
R
D
A
L
V
SGALESTKASE--
L
D
L
E
K
G
L
E
M
R
K
W
V
L
S
G
ILAS
E
E
T
Y
L
S
H
L
E
A
L
L-LPMKPLKAAATT----SQPV
L
T
S
Q
Q
I
E
T
I
F
F
KV
P
E
L
Y
E
I
H
K
E
F
Y
D
G
L
F
P
R
V
Q
Q
W
--------
S
--
H
--
Q
--
Q
R
V
G
D
L
F
Q
K
L
------
A
S
------Q------L
G
V
Y
R
A
F
V
D
NYG
V
A
M
E
M
A
E
K
C
C
Q
ANA
Q
F
A
E
I
S
E
N
L
R
ARSNKDAKDPTT
K
N
S
L
E
T
L
L
Y
K
P
V
D
R
V
T
R
S
T
L
V
L
H
D
L
L
K
HTPASHPD
H
P
L
L
Q
D
A
L
R
I
S
Q
N
F
L
S
S
I
N
E
EITPRRQSMTVK-------------K-------------------------
G
-----------------------
E
H
------------------
R
Q
L
L
K
D
-
S
F
M
V
E
L
-
V
-
E
G
A
R
K
L
R
H
V
F
L
F
T
D
L
L
L
C
T
K
L
K
KQS-------G-------GKT
Q
Q
Y
D
C
------
K
W
Y
I
PLT
D
L
S
F
Q
M
V
D
E
L
E
AVPNIPLVPDEELD
A
L
K
I
K
I
S
Q
I
K
N
D
I
Q
R
E
K
RANKG
S
K
A
T
E
R
L
K
K
K
LSEQE
S
L
L
L
L
MSP
S
M
A
F
R
V
H----SR---NG
K
S
Y
T
F
L
ISSDY
E
R
A
E
W
R
E
N
I
R
E
Q
Q
K
K
C
F
R
SFSL
T
S
V
E
L
Q
M
L
TNS
C
V
K
L
Q
T
V
H
SI
P
L
T
INKEDDESP
G
L
Y
G
F
L
N
V
I
V
HSATGFKQSS
N
L
Y
C
T
L
E
VDSF
G
Y
F
V
N
K
A
K
T
R
V
Y
RDTAEPNWN
E
E
F
E
I
E
LEGS
Q
T
L
R
I
L
C
Y
E
K
CYNKTKIPKEDGE
S
T
D
R
LMGKG
Q
V
Q
L
D
P
Q
ALQDRDW
Q
R
T
V
I
A
MN
G
I
E
V
K
L
S
V
K
FNSREF
S
L
K
RMPSRKQT
G
V
F
G
V
K
I
A
V
V
T
KRERSKV
P
Y
I
V
R
Q
C
V
E
E
I
E
RRG
M
E
EV
G
I
Y
R
VSGV
A
T
D
I
Q
A
L
K
A
A
FDVNNK--
D
V
S
V
M
M
S
EM-
D
--
V
N
A
I
A
G
T
L
K
L
Y
F
R
ELPEPLFTDEFY
P
N
F
AEGIALSDP
V
A
K
E
S
C
M
L
N
L
L
L
SLPE
A
N
L
L
T
F
L
F
L
L
D
H
L
K
R
V
A
E
K
E
A
V
N
K
M
S
L
H
N
L
A
T
V
FGPTLLRPSEKESKLPANPSQ
P
I
T
-MTDS
W
S
L
E
V
M
S
Q
V
Q
V
L
L
Y
F
L
Q
LEAIPAPDSKR
Q
S
I
L
FSTEV
1
PsiBlast_PDB
91.41
100%
-139
- C2 -
-
5N6R
-
A:
[3-218]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
E
--
L
D
L
E
K
G
L
E
M
R
K
W
V
L
S
G
I
L
A
S
E
E
T
Y
L
S
H
L
E
A
L
L
-
L
P
M
K
P
L
K
A
A
A
T
T
----
S
Q
P
V
L
T
S
Q
Q
I
E
T
I
F
F
K
V
P
E
L
Y
E
I
H
K
E
F
Y
D
G
L
F
P
R
V
Q
Q
W
--------
S
--
H
--
Q
--
Q
R
V
G
D
L
F
Q
K
L
------
A
S
------
Q
------
L
G
V
Y
R
A
F
V
D
N
Y
G
V
A
M
E
M
A
E
K
C
C
Q
A
N
A
Q
F
A
E
I
S
E
N
L
R
A
R
S
N
K
D
A
K
D
P
T
T
K
N
S
L
E
T
L
L
Y
K
P
V
D
R
V
T
R
S
T
L
V
L
H
D
L
L
K
H
T
P
A
S
H
P
D
H
P
L
L
Q
D
A
L
R
I
S
Q
N
F
L
S
S
I
N
E
E
I
T
P
R
R
Q
S
M
T
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.27
100%
-153
- C2 -
-
5N7E
-
B:
[6-205]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
--
L
D
L
E
K
G
L
E
M
R
K
W
V
L
S
G
I
L
A
S
E
E
T
Y
L
S
H
L
E
A
L
L
-
L
P
M
K
P
L
K
A
A
A
T
T
----
S
Q
P
V
L
T
S
Q
Q
I
E
T
I
F
F
K
V
P
E
L
Y
E
I
H
K
E
F
Y
D
G
L
F
P
R
V
Q
Q
W
--------
S
--
H
--
Q
--
Q
R
V
G
D
L
F
Q
K
L
------
A
S
------
Q
------
L
G
V
Y
R
A
F
V
D
N
Y
G
V
A
M
E
M
A
E
K
C
C
Q
A
N
A
Q
F
A
E
I
S
E
N
L
R
--------------
S
L
E
T
L
L
Y
K
P
V
D
R
V
T
R
S
T
L
V
L
H
D
L
L
K
H
T
P
A
S
H
P
D
H
P
L
L
Q
D
A
L
R
I
S
Q
N
F
L
S
S
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
61.81
19%
14
- C2 -
-
2Z0Q
-
ARHG3_MOUSE
A:
[11-346]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
L
T
A
K
E
I
K
R
Q
E
A
I
F
E
L
S
Q
G
E
E
D
L
I
E
D
L
K
L
A
K
K
A
Y
H
D
P
M
L
K
L
---------
S
I
M
T
E
Q
E
L
N
Q
I
F
G
T
L
D
S
L
I
P
L
H
E
E
L
L
S
Q
L
R
D
V
R
K
P
D
--------
G
--
S
--
T
--
E
H
V
G
P
I
L
V
G
W
------
L
P
------
C
------
L
S
S
Y
D
S
Y
C
S
N
Q
V
A
A
K
A
L
L
D
H
K
-
K
Q
D
H
R
V
Q
D
F
-------------------
D
L
W
N
F
L
D
I
P
R
S
R
L
V
K
Y
P
L
L
L
R
E
I
L
R
H
T
P
N
D
N
P
D
Q
Q
H
L
E
E
A
I
N
I
I
Q
G
I
V
A
E
I
N
T
K
T
G
E
S
E
C
R
Y
Y
K
E
RLLYLEEGQKDSL
I
-------------------------
D
-----------------------
S
S
------------------
R
V
L
C
C
H
-
G
E
L
K
N
-----
N
R
G
V
K
L
H
V
F
L
F
Q
E
V
L
V
I
T
R
A
V
T
H
N
-------
E
-------
Q
-
L
C
Y
Q
L
Y
------
R
Q
P
I
P
V
K
D
L
T
L
E
D
L
Q
D
G
E
V
R
L
G
------
G
S
L
------------
A
F
--------------------------
S
N
N
E
R
V
K
N
F
F
R
V
S
----
F
K
NGS
Q
S
Q
T
H
S
L
Q
A
N
D
T
F
N
K
Q
Q
W
L
N
C
I
R
Q
A
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
61.07
17%
30
- C2 -
-
4D0N
1
B:
[8-370]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
S
W
S
R
I
I
D
S
K
FL
K
Q
Q
K
K
D
V
V
K
R
Q
E
V
I
Y
E
L
M
Q
T
E
F
H
H
V
R
T
L
K
I
M
S
G
V
Y
S
Q
G
M
M
A
D
---------
L
L
F
E
Q
Q
M
V
E
K
L
F
P
C
L
D
E
L
I
S
I
H
S
Q
F
F
Q
R
I
L
E
R
K
K
E
S
LVDKSEKN
F
--
L
--
I
--
K
R
I
G
D
V
L
V
N
Q
FSGEN-
A
E
------
R
L-----
K
K
T
Y
G
K
F
C
G
Q
H
N
Q
S
V
N
Y
F
K
D
L
Y
A
K
D
K
R
F
Q
A
F
V
K
K
K
M
S
S
------
S
V
V
R
R
L
G
I
P
E
C
I
L
L
V
T
Q
R
I
T
K
Y
P
V
L
F
Q
R
I
L
Q
C
T
K
D
N
E
V
E
Q
E
D
L
A
Q
S
L
S
L
V
K
D
V
I
G
A
V
D
S
K
V
A
S
Y
E
K
K
V
R
L
N
-------------
E
-------------------------
I
YTKTDSKSIMRMKSGQMFAKEDL
K
R
------------------
K
K
L
V
R
D
-
G
S
V
F
L
K
-
N
A
A
G
R
L
K
E
V
Q
A
V
L
L
T
D
I
L
V
F
L
Q
E
K
D
--------------------
Q
K
Y
I
F
ASLDQK
S
T
V
I
S
L
K
K
L
I
V
R
E
V
A
H
E
E
-----------------------------------------------------------
K
G
L
F
L
I
S
MG--
M
T
---
D
P
E
M
V
E
V
H
A
S
S
K
E
E
R
N
S
W
I
Q
I
I
Q
D
T
I
N
T
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Blastp_CBE
60.04
34%
-170
- C3 -
-
5HPY
2
D:
[14-197]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
C
----------
S
V
P
I
V
L
E
K
L
L
E
H
V
E
M
H
G
L
Y
T
E
G
L
Y
R
K
S
G
A
A
N
R
T
R
E
L
R
Q
A
L
Q
T
D
----
P
A
A
V
K
L
E
N
F
-
P
--
I
H
A
I
T
G
V
L
K
Q
W
L
R
E
L
P
E
P
L
M
T
F
A
Q
Y
G
D
F
L
R
A
V
E
L
P
E
K
Q
E
Q
L
A
A
I
Y
A
V
L
E
H
L
P
E
A
N
H
N
S
L
E
R
L
I
F
H
L
V
K
V
A
L
L
E
D
V
N
R
M
S
P
G
A
L
A
I
I
F
A
P
C
L
L
R
-------
C
P
---
S
D
P
L
T
S
M
K
D
--
V
L
K
I
T
T
C
V
E
M
L
I
------------------------
47
HHSearch
59.61
17%
-7
- C2 -
-
1XCG
-
ARHGB_HUMAN
E:
[726-1080]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
L
T
Q
R
E
I
D
R
Q
E
V
I
N
E
L
F
V
T
E
A
S
H
L
R
T
L
R
V
L
D
L
I
F
Y
Q
R
M
K
K
E
---------
N
L
M
P
R
E
E
L
A
R
L
F
P
N
L
P
E
L
I
E
I
H
N
S
W
C
E
A
M
K
K
L
R
E
E
G
--------
P
--
I
--
I
--
K
E
I
S
D
L
M
L
A
R
------
F
D
------
G
PAREEL
Q
Q
V
A
A
Q
F
C
S
Y
Q
S
I
A
L
E
L
I
K
T
K
Q
R
K
E
S
R
F
Q
L
F
M
Q
E
A
E
S
H
------
P
Q
C
R
R
L
Q
L
R
D
L
I
I
S
E
M
Q
R
L
T
K
Y
P
L
L
L
E
S
I
I
K
H
T
E
G
G
T
S
E
H
E
K
L
C
R
A
R
D
Q
C
R
E
I
L
K
Y
V
N
E
A
V
K
Q
T
E
N
R
H
R
L
E
-------------
G
YQKRLDATALERASNPLAAEFKSLD
L
-----------------------
T
T
------------------
R
K
M
I
H
E
-
G
P
L
T
W
R
I
S
-
K
D
K
T
L
D
L
H
V
L
L
L
E
D
L
L
V
L
L
Q
K
Q
D
E
K
-------
L
LLKCHSK------
T
F
------
S
P
V
L
K
L
N
A
V
L
I
R
S
V
A
T
D
K
------------------------------------------------------------
R
A
F
F
I
I
CTSK
L
G
---
P
P
Q
I
Y
E
L
V
A
L
T
S
S
D
K
N
T
W
M
E
L
L
E
E
A
V
R
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
59.40
17%
42
- C2 -
-
3MPX
-
A:
[20-335]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
R
A
L
V
I
A
Q
E
L
L
S
S
E
K
A
Y
V
E
M
L
Q
H
L
N
L
D
F
H
G
A
V
M
R
A
L
D
D
MDHE--
D
T
L
A
R
E
E
L
R
Q
G
L
S
E
L
P
A
I
H
D
L
H
Q
G
I
L
E
E
L
E
E
R
L
S
N
W
--------
E
--
S
--
Q
--
Q
K
V
A
D
V
F
L
A
R
------
E
Q
------
G
------
F
D
H
H
A
T
H
I
L
Q
F
D
R
Y
L
G
L
L
S
E
N
C
L
H
S
P
R
L
A
A
A
V
R
E
F
E
Q
S
------------
T
A
K
H
R
L
L
R
V
V
Q
R
L
F
Q
Y
Q
V
L
L
T
D
Y
L
N
N
L
C
P
D
S
A
E
Y
D
N
T
Q
G
A
L
S
L
I
S
K
V
T
D
R
A
N
D
S
M
E
Q
G
E
N
L
Q
K
L
V
-------------
H
IEHSVRGQGDLL-------------
Q
-----------------------
P
G
------------------
R
E
F
L
K
E
-
G
T
L
M
K
V
-
T
-
G
K
N
R
R
P
R
H
L
F
L
M
N
D
V
L
L
Y
T
Y
P
Q
K
-------------------
D
G
K
Y
R
L
------
K
N
T
L
A
-----
V
S
R
P
V
M
E
K
----------------------------------------------------------
V
P
Y
A
L
K
I
E
----
T
----
S
E
S
C
L
M
L
S
A
S
S
C
A
E
R
D
E
W
Y
G
C
L
S
R
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Blastp_CBE
58.78
34%
-178
- C3 -
-
5HPY
2
MYO9B_HUMAN
A:
[12-197]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
H
F
G
V
C
V
---------
S
V
P
I
V
L
E
K
L
L
E
H
V
E
M
H
G
L
Y
T
E
G
L
Y
R
K
S
G
A
A
N
R
T
R
E
L
R
Q
A
L
Q
T
D
----
P
A
A
V
K
L
E
N
F
-
P
--
I
H
A
I
T
G
V
L
K
Q
W
L
R
E
L
P
E
P
L
M
T
F
A
Q
Y
G
D
F
L
R
A
V
E
L
P
E
K
Q
E
Q
L
A
A
I
Y
A
V
L
E
H
L
P
E
A
N
H
N
S
L
E
R
L
I
F
H
L
V
K
V
A
L
L
E
D
V
N
R
M
S
P
G
A
L
A
I
I
F
A
P
C
L
L
R
-------
C
----
S
D
P
L
T
S
M
K
D
--
V
L
K
I
T
T
C
V
E
M
L
I
------------------------
61
Fugue
57.29
11%
3
- C2 -
-
1TXD
-
ARHGC_HUMAN
A:
[766-1138]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
N
W
Q
Q
L
V
S
R
E
V
L
--
L
G
L
K
P
C
E
I
K
R
Q
E
V
I
N
E
L
F
Y
T
E
R
A
H
V
R
T
L
K
V
L
D
-
Q
V
F
----
Y
Q
R
V
S
----
R
E
G
I
L
S
P
S
E
L
R
K
I
F
S
N
L
E
D
I
L
Q
L
H
I
G
L
N
E
Q
M
K
A
V
R
K
R
N
--------
E
--
T
--
S
VI
D
Q
I
G
E
D
L
L
T
W
FSGPGE
E
K
------
L
------
K
H
A
A
A
T
F
C
S
N
Q
P
F
A
L
E
M
I
K
S
R
Q
K
K
D
S
R
F
Q
T
F
V
Q
D
A
E
S
N
------
P
L
C
R
R
L
Q
L
K
D
I
I
P
T
Q
M
Q
R
L
T
K
Y
P
L
L
L
D
N
I
A
K
Y
T
E
-
W
P
T
E
R
E
K
V
K
K
A
A
D
H
C
R
Q
I
L
N
F
V
N
Q
A
V
K
E
A
E
N
K
Q
R
L
E
-------------
D
-------------------------
Y
-----------------------
Q
R
RLDTSSLVEELRNLDLTK
R
K
M
I
H
E
G
P
L
V
W
K
V
-
N
-
R
D
K
T
I
D
L
Y
T
L
L
L
E
D
I
L
V
L
L
Q
K
Q
D
D
R
-------
L
-------
V
L
R
C
T
F
--------
S
P
V
I
K
L
S
T
V
L
V
R
Q
V
A
T
-
N
K
A
L
F
V
I
S
M
S
D
N
G
A
Q
I
Y
E
L
V
A
Q
T
V
S
E
K
T
V
W
Q
D
L
I
C
R
M
A
A
S
V
K
E
Q
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
56.97
14%
24
- C2 -
-
1TXD
-
ARHGC_HUMAN
A:
[779-1135]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
K
P
C
E
I
K
R
Q
E
V
I
N
E
L
F
Y
T
E
R
A
H
V
R
T
L
K
V
L
D
Q
V
F
Y
Q
R
V
S
R
E
---------
G
I
L
S
P
S
E
L
R
K
I
F
S
N
L
E
D
I
L
Q
L
H
I
G
L
N
E
Q
M
K
A
V
R
K
R
N
--------
E
TS
V
--
I
--
D
Q
I
G
E
D
L
L
T
W
------
F
S
GPGEEK
L
------
K
H
A
A
A
T
F
C
S
N
Q
P
F
A
L
E
M
I
K
S
R
Q
K
K
D
S
R
F
Q
T
F
V
Q
D
A
E
S
N
------
P
L
C
R
R
L
Q
L
K
D
I
I
P
T
Q
M
Q
R
L
T
K
Y
P
L
L
L
D
N
I
A
K
Y
T
E
W
-
P
T
E
R
E
K
V
K
K
A
A
D
H
C
R
Q
I
L
N
F
V
N
Q
A
V
K
E
A
E
N
K
Q
R
L
E
-------------
D
YQRRLDTSSLVEELRNLD-------
L
-----------------------
T
K
------------------
R
K
M
I
H
E
-
G
P
L
V
W
K
-
V
N
R
D
K
T
I
D
L
Y
T
L
L
L
E
D
I
L
V
L
L
Q
K
Q
D
D
R
LVLRC----------------
T
F
------
S
P
V
I
K
L
S
T
V
L
V
R
Q
V
A
T
-
N
-----------------------------------------------------------
K
A
L
F
V
I
S
MS--
D
N
---
G
A
Q
I
Y
E
L
V
A
Q
T
V
S
E
K
T
V
W
Q
D
L
I
C
R
M
A
A
S
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
55.70
41%
-66
- C3 -
-
6GVC
1
RHG12_MOUSE
R:
[38-211]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
G
S
N
L
A
N
L
C
Q
R
E
N
G
T
V
P
K
F
V
K
L
C
I
E
H
V
E
E
H
G
L
D
V
D
G
I
Y
R
V
S
G
N
L
A
V
I
Q
K
L
R
F
A
V
N
H
D
E
K
L-
D
L
N
D
S
K
W
E
--
D
--
I
H
V
I
T
G
A
L
K
M
F
F
R
E
L
P
E
P
L
F
T
F
N
H
F
N
D
F
V
N
A
I
K
-
Q
E
P
R
Q
R
V
T
A
V
K
D
L
I
R
Q
L
P
K
P
N
Q
D
T
M
Q
I
L
F
R
H
L
K
R
V
I
E
N
G
E
K
N
R
M
T
Y
Q
S
I
A
I
V
F
G
P
T
L
L
K
P
-
E
R
E
T
-----------------------------------------------------
24
Blastp_CBE
55.21
41%
-71
- C3 -
-
6GVC
1
RHG12_MOUSE
Q:
[38-211]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
G
S
N
L
A
N
L
C
Q
R
E
N
G
T
V
P
K
F
V
K
L
C
I
E
H
V
E
E
H
G
L
D
V
D
G
I
Y
R
V
S
G
N
L
A
V
I
Q
K
L
R
F
A
V
N
H
D
E
K
L-
D
L
N
D
S
K
W
E
--
D
--
I
H
V
I
T
G
A
L
K
M
F
F
R
E
L
P
E
P
L
F
T
F
N
H
F
N
D
F
V
N
A
I
K
-
Q
E
P
R
Q
R
V
T
A
V
K
D
L
I
R
Q
L
P
K
P
N
Q
D
T
M
Q
I
L
F
R
H
L
K
R
V
I
E
N
G
E
K
N
R
M
T
Y
Q
S
I
A
I
V
F
G
P
T
L
L
K
P
-
E
R
E
T
-----------------------------------------------------
14
PsiBlast_PDB
55.14
31%
-152
- C3 -
-
2EE4
-
A:
[9-173]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
N
Y
F
G
M
P
L
Q
D
L
V
T
A
E
K
P
-
I
P
L
F
V
E
K
C
V
E
F
I
E
D
T
G
L
C
T
E
G
L
Y
R
V
S
G
N
K
T
D
Q
D
N
I
Q
K
Q
F
D
-
Q
D
H
--
N
I
N
L
V
S
M
E
V
-
T
--
V
N
A
V
A
G
A
L
K
A
F
F
A
D
L
P
D
P
L
I
P
Y
S
L
H
P
E
L
L
E
A
A
K
I
P
D
K
T
E
R
L
H
A
L
K
E
I
V
K
K
F
H
P
V
N
Y
D
V
F
R
Y
V
I
T
H
L
N
R
V
S
Q
Q
H
K
I
N
L
M
T
A
D
N
L
S
I
C
F
W
P
T
L
M
R
P
----------------------------------------------------------
23
Blastp_CBE
55.01
41%
-68
- C3 -
-
6GVC
1
RHG12_MOUSE
S:
[38-211]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
G
S
N
L
A
N
L
C
Q
R
E
N
G
T
V
P
K
F
V
K
L
C
I
E
H
V
E
E
H
G
L
D
V
D
G
I
Y
R
V
S
G
N
L
A
V
I
Q
K
L
R
F
A
V
N
H
D
E
K
L-
D
L
N
D
S
K
W
E
--
D
--
I
H
V
I
T
G
A
L
K
M
F
F
R
E
L
P
E
P
L
F
T
F
N
H
F
N
D
F
V
N
A
I
K
-
Q
E
P
R
Q
R
V
T
A
V
K
D
L
I
R
Q
L
P
K
P
N
Q
D
T
M
Q
I
L
F
R
H
L
K
R
V
I
E
N
G
E
K
N
R
M
T
Y
Q
S
I
A
I
V
F
G
P
T
L
L
K
P
-
E
R
E
T
-----------------------------------------------------
19
PsiBlast_PDB
54.91
39%
-166
- C3 -
-
2OVJ
1
A:
[17-160]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
S
I
V
V
H
C
V
N
E
I
E
Q
R
G
L
T
E
T
G
L
Y
R
I
S
G
C
D
R
T
V
K
E
L
K
E
K
F
-
L
R
V
K
--
T
V
P
L
L
S
K
V
D
-
D
--
I
H
A
I
C
S
L
L
K
D
F
L
R
N
L
K
E
P
L
L
T
F
R
L
N
R
A
F
M
E
A
A
E
I
T
D
E
D
N
S
I
A
A
M
Y
Q
A
V
G
E
L
P
Q
A
N
R
D
T
L
A
F
L
M
I
H
L
Q
R
V
A
Q
S
P
H
-
T
K
M
D
V
A
N
L
A
K
V
F
G
P
T
I
V
------------------------------------------------------------
52
HHSearch
54.71
14%
34
- C2 -
-
1X86
-
ARHGC_HUMAN
A:
[16-372]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
K
P
C
E
I
K
R
Q
E
V
I
N
E
L
F
Y
T
E
R
A
H
V
R
T
L
K
V
L
D
Q
V
F
Y
Q
R
V
S
R
E
---------
G
I
L
S
P
S
E
L
R
K
I
F
S
N
L
E
D
I
L
Q
L
H
I
G
L
N
E
Q
M
K
A
V
R
K
R
N
--------
E
--
T
SV
I
--
D
Q
I
G
E
D
L
L
T
W
------
F
S
GPGEEK
L
------
K
H
A
A
A
T
F
C
S
N
Q
P
F
A
L
E
M
I
K
S
R
Q
K
K
D
S
R
F
Q
T
F
V
Q
D
A
E
S
N
------
P
L
C
R
R
L
Q
L
K
D
I
I
P
T
Q
M
Q
R
L
T
K
Y
P
L
L
L
D
N
I
A
K
Y
T
E
W
-
P
T
E
R
E
K
V
K
K
A
A
D
H
C
R
Q
I
L
N
F
V
N
Q
A
V
K
E
A
E
N
K
Q
R
L
E
-------------
D
YQRRLDTSSLKLSEYPNVEELRNLD
L
-----------------------
T
K
------------------
R
K
M
I
H
E
-
G
P
L
V
W
K
-
V
N
R
D
K
T
I
D
L
Y
T
L
L
L
E
D
I
L
V
L
L
Q
K
Q
D
D
R
LVLRCHS--------------
T
F
------
S
P
V
I
K
L
S
T
V
L
V
R
Q
V
A
T
D
N
-----------------------------------------------------------
K
A
L
F
V
I
S
MS--
D
N
---
G
A
Q
I
Y
E
L
V
A
Q
T
V
S
E
K
T
V
W
Q
D
L
I
C
R
M
A
A
S
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
54.61
37%
-90
- C3 -
-
1XA6
-
CHIO_HUMAN
A:
[272-438]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
C
C
D
L
T
T
L
V
K
A
H
N
T
Q
R
P
M
V
V
D
I
C
I
R
E
I
E
A
R
G
L
K
S
E
G
L
Y
R
V
S
G
F
T
E
H
I
E
D
V
K
M
A
F
D
R
D
G
E
--
K
A
D
I
S
A
N
V
Y
P
D
--
I
N
I
I
T
G
A
L
K
L
Y
F
R
D
L
P
I
P
V
I
T
Y
D
T
Y
S
K
F
I
D
A
A
K
I
S
N
A
D
E
R
L
E
A
V
H
E
V
L
M
L
L
P
P
A
H
Y
E
T
L
R
Y
L
M
I
H
L
K
K
V
T
M
N
E
K
D
N
F
M
N
A
E
N
L
G
I
V
F
G
P
T
L
M
R
P
P
E
--------------------------------------------------------
5
PsiBlast_PDB
54.44
41%
-36
- C3 -
-
3CXL
-
CHIN_HUMAN
A:
[269-443]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
S
C
D
L
T
T
L
V
K
A
H
T
T
K
R
P
M
V
V
D
M
C
I
R
E
I
E
S
R
G
L
N
S
E
G
L
Y
R
V
S
G
F
S
D
L
I
E
D
V
K
M
A
F
D
R
D
G
E
KA
D
I
S
V
N
M
Y
E
--
D
--
I
N
I
I
T
G
A
L
K
L
Y
F
R
D
L
P
I
P
L
I
T
Y
D
A
Y
P
K
F
I
E
S
A
K
I
M
D
P
D
E
Q
L
E
T
L
H
E
A
L
K
L
L
P
P
A
H
C
E
T
L
R
Y
L
M
A
H
L
K
R
V
T
L
H
E
K
E
N
L
M
N
A
E
N
L
G
I
V
F
G
P
T
L
M
R
S
P
E
L
D
A
M
A
A
L
N
------------------------------------------------
18
PsiBlast_PDB
54.39
39%
-169
- C3 -
-
3W6R
-
RGAP1_HUMAN
A:
[362-505]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
S
I
V
V
H
C
V
N
E
I
E
Q
R
G
L
T
E
T
G
L
Y
R
I
S
G
C
D
R
T
V
K
E
L
K
E
K
F
-
L
R
V
K
--
T
V
P
L
L
S
K
V
D
-
D
--
I
H
A
I
C
S
L
L
K
D
F
L
R
N
L
K
E
P
L
L
T
F
R
L
N
R
A
F
M
E
A
A
E
I
T
D
E
D
N
S
I
A
A
M
Y
Q
A
V
G
E
L
P
Q
A
N
R
D
T
L
A
F
L
M
I
H
L
Q
R
V
A
Q
S
P
H
-
T
K
M
D
V
A
N
L
A
K
V
F
G
P
T
I
V
------------------------------------------------------------
16
PsiBlast_PDB
54.35
37%
-147
- C3 -
-
5C2K
2
RGAP1_HUMAN
A:
[231-387]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
S
I
V
V
H
C
V
N
E
I
E
Q
R
G
L
T
E
T
G
L
Y
R
I
D
G
C
D
R
T
V
K
E
L
K
E
K
F
-
L
R
V
K
--
T
V
P
L
L
S
K
V
D
-
D
--
I
H
A
I
C
S
L
L
K
D
F
L
R
N
L
K
E
P
L
L
T
F
R
L
N
R
A
F
M
E
A
A
E
I
T
D
E
D
N
S
I
A
A
M
Y
Q
A
V
G
E
L
P
Q
A
N
R
D
T
L
A
F
L
M
I
H
L
Q
R
V
A
Q
S
P
H
-
T
K
M
D
V
A
N
L
A
K
V
F
G
P
T
I
V
------
A
H
A
V
P
N
P
D
-
P
V
T
-
M
S
---------------------------------------
17
PsiBlast_PDB
53.73
39%
-163
- C3 -
-
5C2J
2
A:
[24-167]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
S
I
V
V
H
C
V
N
E
I
E
Q
R
G
L
T
E
T
G
L
Y
R
I
S
G
C
D
R
T
V
K
E
L
K
E
K
F
-
L
R
V
K
--
T
V
P
L
L
S
K
V
D
-
D
--
I
H
A
I
C
S
L
L
K
D
F
L
R
N
L
K
E
P
L
L
T
F
R
L
N
R
A
F
M
E
A
A
E
I
T
D
E
D
N
S
I
A
A
M
Y
Q
A
V
G
E
L
P
Q
A
N
R
D
T
L
A
F
L
M
I
H
L
Q
R
V
A
Q
S
P
H
-
T
K
M
D
V
A
N
L
A
K
V
F
G
P
T
I
V
------------------------------------------------------------
12
PsiBlast_PDB
47.57
33%
-38
- C3 -
-
5IRC
2
RHG35_RAT
A:
[5-170]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
N
Y
F
G
V
P
L
T
T
V
V
T
P
E
K
P
-
I
P
I
F
I
E
R
C
I
E
Y
I
E
A
T
G
L
S
T
E
G
I
Y
R
V
S
G
N
K
S
E
M
E
S
L
Q
R
Q
F
D
---
Q
--
D
H
N
L
D
L
A
E
K
-
D
FT
V
N
T
V
A
G
A
M
K
S
F
F
S
E
L
P
D
P
L
V
P
Y
S
M
Q
I
D
L
V
E
A
H
K
I
N
D
R
E
Q
K
L
H
A
L
K
E
V
L
K
K
F
P
K
E
N
H
E
V
F
K
Y
V
I
S
H
L
N
R
V
S
H
N
N
K
V
N
L
M
T
S
E
N
L
S
I
C
F
W
P
T
L
M
R
P
----------------------------------------------------------
25
Blastp_CBE
47.36
34%
-37
- C3 -
-
5IRC
2
B:
[5-170]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
N
Y
F
G
V
P
L
T
T
V
V
T
P
E
K
P
-
I
P
I
F
I
E
R
C
I
E
Y
I
E
A
T
G
L
S
T
E
G
I
Y
R
V
S
G
N
K
S
E
M
E
S
L
Q
R
Q
F
D
---
Q
--
D
H
N
L
D
L
A
E
K
-
D
FT
V
N
T
V
A
G
A
M
K
S
F
F
S
E
L
P
D
P
L
V
P
Y
S
M
Q
I
D
L
V
E
A
H
K
I
N
D
R
E
Q
K
L
H
A
L
K
E
V
L
K
K
F
P
K
E
N
H
E
V
F
K
Y
V
I
S
H
L
N
R
V
S
H
N
N
K
V
N
L
M
T
S
E
N
L
S
I
C
F
W
P
T
L
M
R
P
----------------------------------------------------------