@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : AVR2B_HUMAN: (2019-05-18 )
MTAPWVALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
Atome Classification :
(9 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MTA
P
W
V
A
L
A
L
L
W
G
S
LCAGSGRGEAE
T
R
E
C
I
Y
YNAN
W
E
L
E
RT
N
Q
S
G
L
E
R
CEGEQD
K
R
L
H
C
Y
A
SWRNSSG
T
I
E
L
V
KKGCWLDDFNCY
D
R
Q
E
CVATEENP
Q
V
Y
F
C
CCEGNF
C
N
E
R
F
THLPEAGGPEVTYEPPPT
A
P
T
L
L
T
V
L
A
Y
S
LLPI
G
G
L
S
L
I
V
L
L
A
F
W
M
Y
R
HRKPPYGHVDIHEDPGPPPPSPLVGLK
P
L
Q
L
L
E
I
KARGRF
G
C
V
W
K
A
Q
L
MN
D
F
V
A
V
K
I
F
PLQ
D
K
Q
S
W
Q
S
E
R
E
I
FSTPGM
K
H
E
N
L
L
Q
F
I
A
A
EKRGSN
L
E
V
E
L
W
L
I
T
A
FHDKGS
L
T
D
Y
LKGNII
T
W
N
E
L
C
H
V
A
E
T
M
S
R
G
L
S
Y
L
HEDVPWCRGEGHKPSIAHRDFKSK
N
V
L
L
K
S
D
L
T
A
V
L
A
DF
G
L
A
V
R
FEPGKPPGDTHGQVGTRRYM
A
P
E
V
L
E
G
A
INFQR
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
V
S
R
C
KAADG
P
V
D
E
YML
P
F
E
E
E
IGQHP
S
L
E
E
L
Q
E
V
V
V
H
KKMR
P
T
I
K
D
H
WLKHP
G
L
A
Q
L
C
V
T
I
E
E
CWDH
D
A
E
A
R
L
S
A
G
C
V
E
E
R
V
S
L
I
R
R
SVNGT
T
S
D
C
L
V
S
L
V
T
S
V
TNVDLPPKESSI
1
PsiBlast_PDB
98.90
98%
-107
- C1 -
-
2QLU
1
AVR2B_HUMAN
A:
[15-311]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
L
Q
L
L
E
I
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
M
N
D
F
V
A
V
K
I
F
P
L
Q
D
K
Q
S
W
Q
S
E
R
E
I
F
S
T
P
G
M
K
H
E
N
L
L
Q
F
I
A
A
E
K
R
G
S
N
L
E
V
E
L
W
L
I
T
A
F
H
D
K
G
S
L
T
D
Y
L
K
G
N
I
I
T
W
N
E
L
C
H
V
A
E
T
M
S
R
G
L
S
Y
L
H
E
D
V
P
W
C
R
G
E
G
H
K
P
S
I
A
H
R
D
F
K
S
K
N
V
L
L
K
S
D
L
T
A
V
L
A
D
F
G
L
A
V
R
F
E
P
G
K
P
P
G
D
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
V
S
R
C
K
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
E
L
Q
E
V
V
V
H
K
K
M
R
P
T
I
K
D
H
W
L
K
H
P
G
L
A
Q
L
C
V
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
E
E
R
V
S
L
I
R
R
S
----------------------------
52
HHSearch
91.78
76%
-106
- C1 -
-
4ASX
5
AVR2A_HUMAN
A:
[18-320]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
Y
F
Q
S
M
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
-
K
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
G
-
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
T
---------------------------
51
HHSearch
90.60
76%
-107
- C1 -
-
3SOC
6
AVR2A_HUMAN
B:
[18-320]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
Y
F
Q
S
M
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
-
K
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
--
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
T
---------------------------
4
PsiBlast_PDB
90.48
77%
-106
- C1 -
-
4ASX
4
AVR2A_HUMAN
A:
[25-320]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
K
-
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
G
-
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
T
---------------------------
21
Blastp_CBE
89.83
78%
-100
- C1 -
-
4ASX
6
AVR2A_HUMAN
B:
[25-320]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
K
-
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
G
D
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
T
---------------------------
22
Blastp_CBE
89.54
78%
-106
- C1 -
-
3SOC
5
AVR2A_HUMAN
B:
[25-320]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
K
-
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
--
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
T
---------------------------
3
PsiBlast_PDB
89.00
77%
-100
- C1 -
-
3SOC
7
AVR2A_HUMAN
A:
[25-320]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
K
-
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
G
D
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
T
---------------------------
2
PsiBlast_PDB
88.75
77%
-99
- C1 -
-
3Q4T
13
AVR2A_HUMAN
A:
[25-318]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
K
-
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
G
D
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
-----------------------------
23
Blastp_CBE
88.48
78%
-105
- C1 -
-
3Q4T
10
AVR2A_HUMAN
B:
[25-319]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
L
L
E
V
K
A
R
G
R
F
G
C
V
W
K
A
Q
L
L
N
E
Y
V
A
V
K
I
F
P
I
Q
D
K
Q
S
W
Q
N
E
Y
E
V
Y
S
L
P
G
M
K
H
E
N
I
L
Q
F
I
G
A
E
K
R
G
T
S
V
D
V
D
L
W
L
I
T
A
F
H
E
K
G
S
L
S
D
F
L
K
A
N
V
V
S
W
N
E
L
C
H
I
A
E
T
M
A
R
G
L
A
Y
L
H
E
D
I
P
G
L
K
-
D
G
H
K
P
A
I
S
H
R
D
I
K
S
K
N
V
L
L
K
N
N
L
T
A
C
I
A
D
F
G
L
A
L
K
F
E
A
G
K
S
A
--
T
H
G
Q
V
G
T
R
R
Y
M
A
P
E
V
L
E
G
A
I
N
F
Q
R
D
A
F
L
R
I
D
M
Y
A
M
G
L
V
L
W
E
L
A
S
R
C
T
A
A
D
G
P
V
D
E
Y
M
L
P
F
E
E
E
I
G
Q
H
P
S
L
E
D
M
Q
E
V
V
V
H
K
K
K
R
P
V
L
R
D
Y
W
Q
K
H
A
G
M
A
M
L
C
E
T
I
E
E
C
W
D
H
D
A
E
A
R
L
S
A
G
C
V
G
E
R
I
T
Q
M
Q
R
L
----------------------------