@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : BUB1_HUMAN: (2019-05-18 )
MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGNNMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPPVVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSGAEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTLPDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGLPQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLECKRSRK
Atome Classification :
(3 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MD
T
P
E
N
V
L
Q
M
L
E
A
H
M
Q
SYKGNDP
L
G
E
W
E
R
Y
I
Q
W
V
E
ENFPE
N
K
E
Y
L
I
T
L
L
E
H
L
M
K
E
F
L
D
K
K
KYHND
P
R
F
I
S
Y
C
L
K
F
A
EY
N
S
D
L
H
Q
F
F
E
F
L
Y
NHGIGTLSS
P
L
Y
I
A
WAGHLEAQG
E
L
Q
H
A
S
A
V
L
Q
R
G
I
QN
Q
A
E
P
R
E
F
L
Q
Q
Q
Y
R
L
F
Q
T
R
LTETHLPAQARTSEP
L
H
N
V
Q
V
L
N
Q
M
I
TSKSNPGNN
M
A
C
I
SKNQG
S
E
L
S
G
V
I
S
S
ACDKESNME
R
R
V
I
T
I
SKSE
Y
S
V
H
S
S
L
A
SKV
D
V
E
Q
V
V
M
Y
C
K
E
K
L
IRGESEF
S
F
E
E
L
R
A
Q
K
Y
N
Q
R
R
K
H
E
Q
W
V
N
E
D
R
H
Y
M
K
R
KEA
N
A
F
E
E
Q
L
L
K
Q
K
M
D
E
L
H
K
K
L
H
Q
V
V
E
TSHEDLPASQERSEV
N
P
A
RMGPSVGS
Q
Q
ELRAPCL
P
V
TYQQTPVNMEKNPREAPPVVP
P
L
A
N
A
I
S
A
A
LVSPATSQSIAPPVP
L
K
A
Q
TVT
D
S
M
F
A
V
ASKDAGCVNKSTHEFKPQSG
A
E
I
K
E
GCETHKVANTSSFHTTPNTSL
G
M
V
QATPSKVQPSPTV
H
T
K
E
A
L
G
F
I
M
N
M
FQAPTLPDISD
D
K
D
E
W
Q
SLDQNE
D
A
F
E
A
Q
F
Q
K
N
VRSSGA
W
G
V
N
K
I
I
S
S
L
S
S
A
F
H
V
FEDGNKENYGLPQPKNKPTGA
R
T
F
G
E
R
S
V
S
RLPSKPKEEVP
H
A
E
E
FLDDS
T
V
W
G
I
RCNKTLAPSPKSPGD
F
T
S
A
A
Q
L
ASTPFHKLPV
E
S
V
H
I
LED
K
E
N
V
V
A
K
Q
C
T
Q
A
T
L
D
S
C
EEN
M
V
VPSRDGKFSPIQEK
S
P
K
Q
A
L
S
S
H
M
Y
S
A
S
L
L
RLSQPAAG
G
V
L
T
C
EAELG
V
E
A
C
RLTDTDAAIAEDP
P
D
A
I
A
G
L
Q
A
E
W
M
Q
M
SSLGTVDAPNFIVGNPW
D
D
K
L
I
F
K
L
L
S
G
L
S
K
P
V
S
SYPN
T
F
E
W
Q
CKLPAIKPKTEFQLGS
K
L
V
Y
V
H
H
L
LGE
G
A
F
A
Q
V
Y
E
ATQGDLNDAKNK
Q
K
F
V
L
K
VQKPA
N
P
W
E
F
Y
I
G
T
Q
L
M
E
R
L
K
P
S
M
Q
H
M
F
M
K
F
Y
S
A
H
L
FQNG
S
V
L
V
G
E
L
Y
S
Y
G
T
L
L
N
A
I
N
L
YKN
T
P
E
K
VMPQ
G
L
V
I
S
F
A
M
R
M
L
Y
M
I
E
Q
VHD
C
E
I
I
HGDIKPD
N
F
I
LGNGFLEQDDE
D
D
L
S
A
G
L
A
L
IDLGQSID
M
K
LFPKG
T
I
F
T
A
KCETS
G
F
Q
C
V
E
M
L
SNKPW
N
Y
Q
I
D
Y
F
G
V
A
A
T
V
Y
C
M
L
F
G
T
Y
M
K
V
KNEGGEC
K
P
E
G
L
F
R
RLPH
L
D
M
W
N
E
F
F
H
V
M
LNIPDCHHLP
S
L
D
L
L
R
Q
K
L
K
K
V
F
Q
Q
H
Y
T
N
K
I
R
A
L
R
N
R
L
I
V
L
L
L
E
C
KRSRK
39
HHSearch
98.75
100%
-144
- C1 -
-
6F7B
1
A:
[9-359]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
N
F
I
V
G
N
P
W
D
D
K
L
I
F
K
L
L
S
G
L
S
K
P
V
S
S
Y
P
N
T
F
E
W
Q
C
K
L
P
A
I
K
P
K
T
E
F
Q
L
G
S
K
L
V
Y
V
H
H
L
L
G
E
G
A
F
A
Q
V
Y
E
A
T
Q
------
K
N
K
Q
K
F
V
L
K
V
Q
K
P
A
N
P
W
E
F
Y
I
G
T
Q
L
M
E
R
L
K
P
S
M
Q
H
M
F
M
K
F
Y
S
A
H
L
F
Q
N
G
S
V
L
V
G
E
L
Y
S
Y
G
T
L
L
N
A
I
N
L
Y
K
N
T
P
E
K
V
M
P
Q
G
L
V
I
S
F
A
M
R
M
L
Y
M
I
E
Q
V
H
D
C
E
I
I
H
G
D
I
K
P
D
N
F
I
L
G
N
G
F
L
E
Q
D
D
E
D
D
L
S
A
G
L
A
L
I
D
L
G
Q
S
I
D
M
K
L
F
P
K
G
T
I
F
T
A
K
C
E
T
S
G
F
Q
C
V
E
M
L
S
N
K
P
W
N
Y
Q
I
D
Y
F
G
V
A
A
T
V
Y
C
M
L
F
G
T
Y
M
K
V
K
N
E
--
E
C
K
P
E
G
L
F
R
R
L
P
H
L
D
M
W
N
E
F
F
H
V
M
L
N
I
P
D
C
H
H
L
P
S
L
D
L
L
R
Q
K
L
K
K
V
F
Q
Q
H
Y
T
N
K
I
R
A
L
R
N
R
L
I
V
L
L
L
E
C
K
R
S
--
2
PsiBlast_PDB
98.55
99%
-144
- C1 -
-
6F7B
1
A:
[9-359]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
N
F
I
V
G
N
P
W
D
D
K
L
I
F
K
L
L
S
G
L
S
K
P
V
S
S
Y
P
N
T
F
E
W
Q
C
K
L
P
A
I
K
P
K
T
E
F
Q
L
G
S
K
L
V
Y
V
H
H
L
L
G
E
G
A
F
A
Q
V
Y
E
A
T
Q
------
K
N
K
Q
K
F
V
L
K
V
Q
K
P
A
N
P
W
E
F
Y
I
G
T
Q
L
M
E
R
L
K
P
S
M
Q
H
M
F
M
K
F
Y
S
A
H
L
F
Q
N
G
S
V
L
V
G
E
L
Y
S
Y
G
T
L
L
N
A
I
N
L
Y
K
N
T
P
E
K
V
M
P
Q
G
L
V
I
S
F
A
M
R
M
L
Y
M
I
E
Q
V
H
D
C
E
I
I
H
G
D
I
K
P
D
N
F
I
L
G
N
G
F
L
E
Q
D
D
E
D
D
L
S
A
G
L
A
L
I
D
L
G
Q
S
I
D
M
K
L
F
P
K
G
T
I
F
T
A
K
C
E
T
S
G
F
Q
C
V
E
M
L
S
N
K
P
W
N
Y
Q
I
D
Y
F
G
V
A
A
T
V
Y
C
M
L
F
G
T
Y
M
K
V
K
N
E
--
E
C
K
P
E
G
L
F
R
R
L
P
H
L
D
M
W
N
E
F
F
H
V
M
L
N
I
P
D
C
H
H
L
P
S
L
D
L
L
R
Q
K
L
K
K
V
F
Q
Q
H
Y
T
N
K
I
R
A
L
R
N
R
L
I
V
L
L
L
E
C
K
R
S
--
1
PsiBlast_PDB
95.06
100%
-156
- C1 -
-
4R8Q
1
A:
[16-363]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
V
G
N
P
W
D
D
K
L
I
F
K
L
L
S
G
L
S
K
P
V
S
S
Y
P
N
T
F
E
W
Q
C
K
L
P
A
I
K
P
K
T
E
F
Q
L
G
S
K
L
V
Y
V
H
H
L
L
G
E
G
A
F
A
Q
V
Y
E
A
T
Q
---------
Q
K
F
V
L
K
V
Q
K
P
A
N
P
W
E
F
Y
I
G
T
Q
L
M
E
R
L
K
P
S
M
Q
H
M
F
M
K
F
Y
S
A
H
L
F
Q
N
G
S
V
L
V
G
E
L
Y
S
Y
G
T
L
L
N
A
I
N
L
Y
K
N
T
P
E
K
V
M
P
Q
G
L
V
I
S
F
A
M
R
M
L
Y
M
I
E
Q
V
H
D
C
E
I
I
H
G
D
I
K
P
D
N
F
I
L
G
N
G
F
L
E
-------
S
A
G
L
A
L
I
D
L
G
Q
S
I
D
M
K
L
F
P
K
G
T
I
F
T
A
K
C
E
T
S
G
F
Q
C
V
E
M
L
S
N
K
P
W
N
Y
Q
I
D
Y
F
G
V
A
A
T
V
Y
C
M
L
F
G
T
Y
M
K
V
K
N
E
G
G
E
C
K
P
E
G
L
F
R
R
L
P
H
L
D
M
W
N
E
F
F
H
V
M
L
N
I
P
D
C
H
H
L
P
S
L
D
L
L
R
Q
K
L
K
K
V
F
Q
Q
H
Y
T
N
K
I
R
A
L
R
N
R
L
I
V
L
L
L
E
C
K
R
S
--