@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LIMK2_HUMAN: (2019-05-23 )
MSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGIPLPAELEELDHTVSMQYGLTRDSPP
Atome Classification :
(12 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.-.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSALAGEDVWRCPGCGDHI
A
P
S
Q
I
W
Y
R
TVNETWHGS
C
F
R
C
S
E
C
Q
D
S
L
T
N
W
Y
YEKDG
K
L
YC
P
K
D
Y
W
G
K
F
G
E
F
C
HG
C
S
LLMTG
P
F
M
V
AGEFKYH
P
E
C
F
A
C
M
S
C
K
V
I
I
EDGD
A
Y
A
L
V
Q
H
A
T
L
Y
C
GKCHNEV
V
L
A
P
M
F
E
RL
S
T
E
S
V
Q
E
QLP
Y
S
V
T
L
I
SMPATTEGRRG
F
S
V
S
V
E
S
ACSNY
A
T
T
V
Q
V
K
E
V
N
R
M
H
ISPNNRNAIHPG
D
R
I
L
E
INGT
P
V
R
T
L
R
V
E
E
V
E
D
A
I
S
Q
T
S
Q
T
L
Q
L
L
IEHD
P
V
S
Q
R
L
D
Q
L
R
L
E
A
R
LA
P
H
MQNAGHPHALSTLD
T
K
E
N
L
E
G
T
L
R
R
R
S
L
RRSNSISKSPGPSSPKE
P
L
L
F
SRDISRSESLRCS
S
S
Y
S
Q
Q
I
F
R
P
C
D
L
I
H
G
E
V
LGKGFFG
Q
A
I
K
V
T
HKATG
K
V
M
V
M
K
E
L
I
RC
D
E
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
SLDH
P
N
V
L
K
F
I
G
V
L
YKD
K
K
L
N
L
L
T
E
Y
IEGG
T
L
K
D
F
L
R
SM-DP-F
P
W
Q
Q
K
V
R
F
A
K
G
I
A
S
G
M
A
Y
L
H
S
M
C
I
IHRDLNSH
N
C
L
I
K
LD
K
T
V
V
V
A
D
F
G
L
S
R
L
I
V
E
E
R
KRAPMEKAT
T
K
K
R
T
L
RKNDRK
K
R
Y
T
VVGNPYWMAPEMLNGKSYD
E
T
V
D
I
F
S
F
G
I
V
L
C
E
I
I
G
Q
VYADPDCL
P
R
T
LDFGL
N
V
K
L
F
W
E
KFVPTDCP
P
A
F
F
P
L
A
A
I
C
C
RLEPESRP
A
F
S
K
L
E
D
S
F
E
A
L
S
L
Y
L
G
ELGIPL
P
A
E
L
E
E
L
D
H
T
V
S
M
QYGLTRDSPP
2
PsiBlast_PDB
93.97
100%
-156
- C2 -
-
4TPT
1
LIMK2_HUMAN
A:
[1-302]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
I
H
G
E
V
L
G
K
G
F
F
G
Q
A
I
K
V
T
H
K
A
T
G
K
V
M
V
M
K
E
L
I
R
C
D
E
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
L
D
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
K
L
N
L
L
T
E
Y
I
E
G
G
T
L
K
D
F
L
R
S
M
-
D
P
-
F
P
W
Q
Q
K
V
R
F
A
K
G
I
A
S
G
M
A
Y
L
H
S
M
C
I
I
H
R
D
L
N
S
H
N
C
L
I
K
L
D
K
T
V
V
V
A
D
F
G
L
S
R
L
I
V
-----------------------
K
K
R
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
L
N
G
K
S
Y
D
E
T
V
D
I
F
S
F
G
I
V
L
C
E
I
I
G
Q
V
Y
A
D
P
D
C
L
P
R
T
L
D
F
G
L
N
V
K
L
F
W
E
K
F
V
P
T
D
C
P
P
A
F
F
P
L
A
A
I
C
C
R
L
E
P
E
S
R
P
A
F
S
K
L
E
D
S
F
E
A
L
S
L
Y
L
G
E
L
G
I
P
L
P
A
E
L
E
E
L
D
H
T
V
S
M
Q
Y
G
-------
22
Blastp_CBE
93.59
100%
-164
- C2 -
-
4TPT
1
B:
[1-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
I
H
G
E
V
L
G
K
G
F
F
G
Q
A
I
K
V
T
H
K
A
T
G
K
V
M
V
M
K
E
L
I
R
C
D
E
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
L
D
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
K
L
N
L
L
T
E
Y
I
E
G
G
T
L
K
D
F
L
R
S
M
-
D
P
-
F
P
W
Q
Q
K
V
R
F
A
K
G
I
A
S
G
M
A
Y
L
H
S
M
C
I
I
H
R
D
L
N
S
H
N
C
L
I
K
L
D
K
T
V
V
V
A
D
F
G
L
S
R
L
I
V
--------------------------
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
L
N
G
K
S
Y
D
E
T
V
D
I
F
S
F
G
I
V
L
C
E
I
I
G
Q
V
Y
A
D
P
D
C
L
P
R
T
L
D
F
G
L
N
V
K
L
F
W
E
K
F
V
P
T
D
C
P
P
A
F
F
P
L
A
A
I
C
C
R
L
E
P
E
S
R
P
A
F
S
K
L
E
D
S
F
E
A
L
S
L
Y
L
G
E
L
G
I
P
L
P
A
E
L
E
E
L
D
H
T
V
S
M
Q
Y
G
L
------
21
Blastp_CBE
89.87
100%
-163
- C2 -
-
5NXD
2
B:
[3-305]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
I
H
G
E
V
L
G
K
G
F
F
G
Q
A
I
K
V
T
H
K
A
T
G
K
V
M
V
M
K
E
L
I
R
C
D
E
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
L
D
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
K
L
N
L
L
T
E
Y
I
E
G
G
T
L
K
D
F
L
R
S
M
-
D
P
-
F
P
W
Q
Q
K
V
R
F
A
K
G
I
A
S
G
M
A
Y
L
H
S
M
C
I
I
H
R
D
L
N
S
H
N
C
L
I
K
L
D
K
T
V
V
V
A
D
F
G
L
S
R
L
I
V
--------------------------------
P
Y
W
M
A
P
E
M
L
N
G
K
S
Y
D
E
T
V
D
I
F
S
F
G
I
V
L
C
E
I
I
G
Q
V
Y
A
D
P
D
C
L
P
R
T
L
D
F
G
L
N
V
K
L
F
W
E
K
F
V
P
T
D
C
P
P
A
F
F
P
L
A
A
I
C
C
R
L
E
P
E
S
R
P
A
F
S
K
L
E
D
S
F
E
A
L
S
L
Y
L
G
E
L
G
I
P
L
P
A
E
L
E
E
L
D
H
T
V
S
M
Q
Y
G
L
------
1
PsiBlast_PDB
89.62
100%
-162
- C2 -
-
5NXD
2
LIMK2_HUMAN
A:
[3-305]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
I
H
G
E
V
L
G
K
G
F
F
G
Q
A
I
K
V
T
H
K
A
T
G
K
V
M
V
M
K
E
L
I
R
C
D
E
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
L
D
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
K
L
N
L
L
T
E
Y
I
E
G
G
T
L
K
D
F
L
R
S
M
-
D
P
-
F
P
W
Q
Q
K
V
R
F
A
K
G
I
A
S
G
M
A
Y
L
H
S
M
C
I
I
H
R
D
L
N
S
H
N
C
L
I
K
L
D
K
T
V
V
V
A
D
F
G
L
S
R
L
I
V
--------------------------------
P
Y
W
M
A
P
E
M
L
N
G
K
S
Y
D
E
T
V
D
I
F
S
F
G
I
V
L
C
E
I
I
G
Q
V
Y
A
D
P
D
C
L
P
R
T
L
D
F
G
L
N
V
K
L
F
W
E
K
F
V
P
T
D
C
P
P
A
F
F
P
L
A
A
I
C
C
R
L
E
P
E
S
R
P
A
F
S
K
L
E
D
S
F
E
A
L
S
L
Y
L
G
E
L
G
I
P
L
P
A
E
L
E
E
L
D
H
T
V
S
M
Q
Y
G
L
------
3
PsiBlast_PDB
76.63
67%
-60
- C2 -
-
3S95
11
LIMK1_HUMAN
A:
[1-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
P
H
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
-
D
S
Q
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
D
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
V
--------------------------
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
A
G
-
H
L
P
L
G
P
Q
L
E
Q
L
D
---------------
23
Blastp_CBE
76.18
68%
-56
- C2 -
-
3S95
6
B:
[1-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
P
H
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
-
D
S
Q
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
D
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
V
--------------------------
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
A
G
-
H
L
P
L
G
P
Q
L
E
Q
L
D
---------------
27
HHSearch
76.15
69%
-59
- C2 -
-
3S95
6
B:
[6-301]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
D
S
Q
-
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
D
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
V
--------------------------
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
-
A
G
H
L
P
L
G
P
Q
L
E
Q
L
D
R
G
F
------------
28
HHSearch
76.04
69%
-56
- C2 -
-
5HVK
1
LIMK1_HUMAN
A:
[9-305]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
D
S
Q
-
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
N
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
V
D
-------------------
P
D
R
K
K
R
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
-
A
G
H
L
P
L
G
P
Q
L
E
Q
L
D
R
G
F
------------
24
Blastp_CBE
76.01
67%
-54
- C2 -
-
5HVK
1
C:
[5-302]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
P
H
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
-
D
S
Q
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
N
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
V
--------------------
P
D
R
K
K
R
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
A
G
-
H
L
P
L
G
P
Q
L
E
Q
L
D
---------------
4
PsiBlast_PDB
75.76
67%
-53
- C2 -
-
5L6W
1
L:
[1-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
P
H
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
-
D
S
Q
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
D
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
----------------------
D
R
K
K
R
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
A
G
-
H
L
P
L
G
P
Q
L
E
Q
L
D
---------------
6
PsiBlast_PDB
74.22
66%
-54
- C2 -
-
5HVK
1
LIMK1_HUMAN
A:
[4-302]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
R
P
H
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
-
D
S
Q
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
N
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
G
L
A
R
L
M
V
D
-------------------
P
D
R
K
K
R
Y
T
V
V
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
A
G
-
H
L
P
L
G
P
Q
L
E
Q
L
D
---------------
5
PsiBlast_PDB
73.02
67%
-66
- C2 -
-
5NXC
1
L:
[1-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
P
H
R
I
F
R
P
S
D
L
I
H
G
E
V
L
G
K
G
C
F
G
Q
A
I
K
V
T
H
R
E
T
G
E
V
M
V
M
K
E
L
I
R
F
D
E
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
L
E
H
P
N
V
L
K
F
I
G
V
L
Y
K
D
K
R
L
N
F
I
T
E
Y
I
K
G
G
T
L
R
G
I
I
K
S
M
-
D
S
Q
Y
P
W
S
Q
R
V
S
F
A
K
D
I
A
S
G
M
A
Y
L
H
S
M
N
I
I
H
R
D
L
N
S
H
N
C
L
V
R
E
N
K
N
V
V
V
A
D
F
-------------------------------------
G
N
P
Y
W
M
A
P
E
M
I
N
G
R
S
Y
D
E
K
V
D
V
F
S
F
G
I
V
L
C
E
I
I
G
R
V
N
A
D
P
D
Y
L
P
R
T
M
D
F
G
L
N
V
R
G
F
L
D
R
Y
C
P
P
N
C
P
P
S
F
F
P
I
T
V
R
C
C
D
L
D
P
E
K
R
P
S
F
V
K
L
E
H
W
L
E
T
L
R
M
H
L
A
G
-
H
L
P
L
G
P
Q
L
E
Q
L
D
---------------