@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NEK7_HUMAN: (2019-05-25 )
MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS
Atome Classification :
(5 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MDEQSQGMQGPPVPQFQPQKALRPDMGY
N
T
L
A
N
F
R
I
E
KKIGR
G
Q
F
S
E
V
Y
R
A
A
C
L
LDGV
P
V
A
L
K
K
V
Q
I
F
D
LMD
A
K
A
R
A
D
C
I
K
E
I
D
L
L
K
QLNH
P
N
V
I
K
Y
Y
A
S
F
IEDNE
L
N
I
V
L
E
LAD
A
G
D
L
S
R
M
I
K
H
F
K
K
Q
K
RLI
P
E
R
T
V
W
K
Y
F
V
Q
L
C
S
A
L
E
H
M
H
S
R
R
V
M
H
RDIKPA
N
V
F
I
T
AT
G
V
V
K
L
GDL
G
L
G
R
F
FSSKT
T
A
A
H
SLVGTPYYM
S
P
E
R
I
HENGYN
F
K
S
D
I
W
S
L
G
C
L
L
Y
E
M
A
A
L
QSPFYGDKM
N
L
Y
S
L
C
K
K
I
E
QCDYPPLP
S
D
H
Y
S
E
E
L
R
Q
L
V
N
MCINPDPEKRPD
V
T
Y
V
Y
D
V
A
K
R
M
H
ACTASS
23
HHSearch
95.42
99%
-132
- C1 -
-
6GT1
1
NEK7_HUMAN
B:
[20-300]
-------------------
K
A
L
R
P
D
M
G
Y
N
T
L
A
N
F
R
I
E
K
K
I
G
R
G
Q
F
S
E
V
Y
R
A
A
C
L
L
D
G
V
P
V
A
L
K
K
V
Q
I
F
D
L
M
D
A
K
A
R
A
D
C
I
K
E
I
D
L
H
K
Q
L
N
H
P
N
V
I
K
F
Y
A
S
F
I
E
D
N
E
L
N
I
V
L
E
L
A
D
A
G
D
L
S
R
M
I
K
H
F
K
K
Q
K
R
L
I
P
E
R
T
V
W
K
Y
F
V
Q
L
C
S
A
L
E
H
M
H
S
R
R
V
M
H
R
D
I
K
P
A
N
V
F
I
T
A
T
G
V
V
K
L
G
D
F
G
L
G
------------
L
V
G
T
P
Y
Y
M
S
P
E
R
I
H
E
N
G
Y
N
F
K
S
D
I
W
S
L
G
C
L
L
Y
E
M
A
A
L
Q
S
P
F
Y
G
D
K
M
N
L
Y
S
L
C
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Y
S
E
E
L
R
Q
L
V
N
M
C
I
N
P
D
P
E
K
R
P
D
V
T
Y
V
Y
D
V
A
K
R
M
H
A
C
T
A
--
22
Blastp_CBE
95.42
99%
-132
- C1 -
-
6GT1
1
NEK7_HUMAN
B:
[20-300]
-------------------
K
A
L
R
P
D
M
G
Y
N
T
L
A
N
F
R
I
E
K
K
I
G
R
G
Q
F
S
E
V
Y
R
A
A
C
L
L
D
G
V
P
V
A
L
K
K
V
Q
I
F
D
L
M
D
A
K
A
R
A
D
C
I
K
E
I
D
L
H
K
Q
L
N
H
P
N
V
I
K
F
Y
A
S
F
I
E
D
N
E
L
N
I
V
L
E
L
A
D
A
G
D
L
S
R
M
I
K
H
F
K
K
Q
K
R
L
I
P
E
R
T
V
W
K
Y
F
V
Q
L
C
S
A
L
E
H
M
H
S
R
R
V
M
H
R
D
I
K
P
A
N
V
F
I
T
A
T
G
V
V
K
L
G
D
F
G
L
G
------------
L
V
G
T
P
Y
Y
M
S
P
E
R
I
H
E
N
G
Y
N
F
K
S
D
I
W
S
L
G
C
L
L
Y
E
M
A
A
L
Q
S
P
F
Y
G
D
K
M
N
L
Y
S
L
C
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Y
S
E
E
L
R
Q
L
V
N
M
C
I
N
P
D
P
E
K
R
P
D
V
T
Y
V
Y
D
V
A
K
R
M
H
A
C
T
A
--
4
PsiBlast_PDB
94.35
99%
-142
- C1 -
-
6GT1
1
NEK7_HUMAN
A:
[21-300]
--------------------
A
L
R
P
D
M
G
Y
N
T
L
A
N
F
R
I
E
K
K
I
G
R
G
Q
F
S
E
V
Y
R
A
A
C
L
L
D
G
V
P
V
A
L
K
K
V
Q
I
F
D
L
M
D
A
K
A
R
A
D
C
I
K
E
I
D
L
H
K
Q
L
N
H
P
N
V
I
K
F
Y
A
S
F
I
E
D
N
E
L
N
I
V
L
E
L
A
D
A
G
D
L
S
R
M
I
K
H
F
K
K
Q
K
R
L
I
P
E
R
T
V
W
K
Y
F
V
Q
L
C
S
A
L
E
H
M
H
S
R
R
V
M
H
R
D
I
K
P
A
N
V
F
I
T
A
T
G
V
V
K
L
G
D
F
G
L
-------------
L
V
G
T
P
Y
Y
M
S
P
E
R
I
H
E
N
G
Y
N
F
K
S
D
I
W
S
L
G
C
L
L
Y
E
M
A
A
L
Q
S
P
F
Y
G
D
K
M
N
L
Y
S
L
C
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Y
S
E
E
L
R
Q
L
V
N
M
C
I
N
P
D
P
E
K
R
P
D
V
T
Y
V
Y
D
V
A
K
R
M
H
A
C
T
A
--
2
PsiBlast_PDB
93.95
100%
-144
- C1 -
-
2WQN
1
NEK7_HUMAN
A:
[21-300]
--------------------
A
L
R
P
D
M
G
Y
N
T
L
A
N
F
R
I
E
K
K
I
G
R
G
Q
F
S
E
V
Y
R
A
A
C
L
L
D
G
V
P
V
A
L
K
K
V
Q
I
F
D
L
M
D
A
K
A
R
A
D
C
I
K
E
I
D
L
L
K
Q
L
N
H
P
N
V
I
K
Y
Y
A
S
F
I
E
D
N
E
L
N
I
V
L
E
L
A
D
A
G
D
L
S
R
M
I
K
H
F
K
K
Q
K
R
L
I
P
E
R
T
V
W
K
Y
F
V
Q
L
C
S
A
L
E
H
M
H
S
R
R
V
M
H
R
D
I
K
P
A
N
V
F
I
T
A
T
G
V
V
K
L
G
D
L
------------------
T
P
Y
Y
M
S
P
E
R
I
H
E
N
G
Y
N
F
K
S
D
I
W
S
L
G
C
L
L
Y
E
M
A
A
L
Q
S
P
F
Y
---
M
N
L
Y
S
L
C
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Y
S
E
E
L
R
Q
L
V
N
M
C
I
N
P
D
P
E
K
R
P
D
V
T
Y
V
Y
D
V
A
K
R
M
H
A
C
T
A
--
21
Blastp_CBE
92.33
99%
-137
- C1 -
-
6GT1
1
NEK7_HUMAN
C:
[27-300]
--------------------------
G
Y
N
T
L
A
N
F
R
I
E
K
K
I
G
R
G
Q
F
S
E
V
Y
R
A
A
C
L
L
D
G
V
P
V
A
L
K
K
V
Q
I
F
D
L
M
D
A
K
A
R
A
D
C
I
K
E
I
D
L
H
K
Q
L
N
H
P
N
V
I
K
F
Y
A
S
F
I
E
D
N
E
L
N
I
V
L
E
L
A
D
A
G
D
L
S
R
M
I
K
H
F
K
K
Q
K
R
L
I
P
E
R
T
V
W
K
Y
F
V
Q
L
C
S
A
L
E
H
M
H
S
R
R
V
M
H
R
D
I
K
P
A
N
V
F
I
T
A
T
G
V
V
K
L
G
D
F
-----------------
G
T
P
Y
Y
M
S
P
E
R
I
H
E
N
G
Y
N
F
K
S
D
I
W
S
L
G
C
L
L
Y
E
M
A
A
L
Q
S
P
F
Y
G
D
K
M
N
L
Y
S
L
C
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Y
S
E
E
L
R
Q
L
V
N
M
C
I
N
P
D
P
E
K
R
P
D
V
T
Y
V
Y
D
V
A
K
R
M
H
A
C
T
A
--