@TOME V3
(Feb 2022)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : DCLK1_HUMAN: (2019-04-28 )
MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF
Atome Classification :
(4 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSFGRDM
E
L
E
HFD
E
R
D
K
A
Q
R
YSRGSRVNGLPSPTHSA
H
C
S
F
Y
R
T
R
T
L
Q
T
L
S
SEKKA
K
K
V
R
F
Y
RNGD
R
Y
F
K
G
I
V
Y
A
I
S
P
D
R
F
R
S
F
E
A
L
L
A
D
L
T
R
T
L
SDNVNLPQG
V
R
T
I
Y
T
I
D
G
L
K
K
I
S
S
L
D
Q
L
VEGE
S
Y
VCGSI
E
P
F
K
K
L
E
YTKNVNP
N
W
S
V
N
V
K
TT
S
A
S
R
A
V
S
S
L
ATAKG
S
P
S
E
V
R
ENKDF
I
R
P
K
L
V
T
I
I
R
SGV
K
P
R
K
A
V
R
I
L
LNKK
T
A
H
S
F
E
Q
V
L
T
D
I
T
D
A
I
KL
D
S
G
V
V
K
R
L
YTLDG
K
Q
V
M
C
L
Q
D
FFGDD
D
I
F
I
A
CGPEKFRYQDDFLLDESE
C
R
V
V
KSTS
Y
T
K
IASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTS
P
G
S
L
R
K
Q
R
SSQHGGSSTSL
A
S
T
K
V
CSSMDENDGPG
E
E
V
S
EEGFQI
P
A
T
I
T
E
R
YKVG
R
T
IGD
G
N
F
A
V
V
K
E
C
V
E
R
S
T
A
R
E
Y
A
L
K
I
I
K
KSKCR
G
K
E
H
M
I
Q
N
E
V
S
I
L
R
RVKHP
N
I
V
L
L
I
EEMDV
P
T
E
L
Y
L
V
M
E
L
VKGG
D
L
F
D
A
I
TSTNKYTERDAS
G
M
L
Y
N
L
A
S
A
I
K
Y
L
H
S
L
N
I
V
HRDIKPE
N
L
L
V
Y
EHQDGSKSLKLGDFG
L
A
T
IVDGP
L
Y
T
VCGTPTY
V
A
P
E
I
I
AETGY
G
L
K
V
D
I
W
A
A
G
V
I
T
Y
I
L
LCGFPPFRGSGD
D
Q
E
V
L
F
D
Q
I
L
MGQVDFPSPYWDNV
S
D
S
A
K
E
L
I
T
M
M
L
L
VD
V
D
Q
R
F
S
A
V
Q
V
L
EHPWVNDDGLPEN
E
H
Q
L
S
V
A
G
K
I
K
K
H
FNTGPKPNSTAA
G
V
S
V
I
A
TTAL
D
K
E
R
Q
V
F
R
R
RR
N
Q
D
V
R
S
RYKAQPAPPELNSESEDYSPSSSETVRSPNSPF
2
PsiBlast_PDB
97.57
99%
-133
- C2 -
-
5JZN
1
DCLK1_HUMAN
A:
[10-279]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
Q
I
P
A
T
I
T
E
R
Y
K
V
G
R
T
I
G
D
G
N
F
A
V
V
K
E
C
V
E
R
S
T
A
R
E
Y
A
L
K
I
I
K
K
S
K
C
R
G
K
E
H
M
I
Q
N
E
V
S
I
L
R
R
V
K
H
P
N
I
V
L
L
I
E
E
M
D
V
P
T
E
L
Y
L
V
M
E
L
V
K
G
G
D
L
F
D
A
I
T
S
T
N
K
Y
T
E
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Y
L
H
S
L
N
I
V
H
R
D
I
K
P
E
N
L
L
V
Y
E
H
Q
D
G
S
K
S
L
K
L
G
D
F
G
L
A
T
I
V
D
G
P
L
Y
T
V
C
G
T
P
T
Y
V
A
P
E
I
I
A
E
T
G
Y
G
L
K
V
D
I
W
A
A
G
V
I
T
Y
I
L
L
C
G
F
P
P
F
R
G
S
--
D
Q
E
V
L
F
D
Q
I
L
M
G
Q
V
D
F
P
S
P
Y
W
D
N
V
S
D
S
A
K
E
L
I
T
M
M
L
L
V
D
V
D
Q
R
F
S
A
V
Q
V
L
E
H
P
W
V
N
--------------------------------------------------------------------------------------------
1
PsiBlast_PDB
95.78
99%
-128
- C2 -
-
5JZJ
2
DCLK1_HUMAN
A:
[22-296]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
S
E
E
G
F
Q
I
P
A
T
I
T
E
R
Y
K
V
G
R
T
I
G
D
G
N
F
A
V
V
K
E
C
V
E
R
S
T
A
R
E
Y
A
L
K
I
I
K
K
S
K
C
R
G
K
E
H
M
I
Q
N
E
V
S
I
L
R
R
V
K
H
P
N
I
V
L
L
I
E
E
M
D
V
P
T
E
L
Y
L
V
M
E
L
V
K
G
G
D
L
F
D
A
I
T
S
T
N
K
Y
T
E
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Y
L
H
S
L
N
I
V
H
R
D
I
K
P
E
N
L
L
V
Y
E
H
Q
D
G
S
K
S
L
K
L
G
D
F
G
L
A
T
I
V
D
G
P
L
Y
T
V
C
G
T
P
T
Y
V
A
P
E
I
I
A
E
T
G
Y
G
L
K
V
D
I
W
A
A
G
V
I
T
Y
I
L
L
C
G
F
P
P
F
R
G
S
----
E
V
L
F
D
Q
I
L
M
G
Q
V
D
F
P
S
P
Y
W
D
N
V
S
D
S
A
K
E
L
I
T
M
M
L
L
V
D
V
D
Q
R
F
S
A
V
Q
V
L
E
H
P
W
V
N
--------------------------------------------------------------------------------------------
22
Blastp_CBE
95.05
99%
-131
- C2 -
-
5JZN
1
B:
[11-279]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
I
P
A
T
I
T
E
R
Y
K
V
G
R
T
I
G
D
G
N
F
A
V
V
K
E
C
V
E
R
S
T
A
R
E
Y
A
L
K
I
I
K
K
S
K
C
R
G
K
E
H
M
I
Q
N
E
V
S
I
L
R
R
V
K
H
P
N
I
V
L
L
I
E
E
M
D
V
P
T
E
L
Y
L
V
M
E
L
V
K
G
G
D
L
F
D
A
I
T
S
T
N
K
Y
T
E
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Y
L
H
S
L
N
I
V
H
R
D
I
K
P
E
N
L
L
V
Y
E
H
Q
D
G
S
K
S
L
K
L
G
D
F
G
L
A
T
I
V
D
G
P
L
Y
T
V
C
G
T
P
T
Y
V
A
P
E
I
I
A
E
T
G
Y
G
L
K
V
D
I
W
A
A
G
V
I
T
Y
I
L
L
C
G
F
P
P
F
R
G
S
---
Q
E
V
L
F
D
Q
I
L
M
G
Q
V
D
F
P
S
P
Y
W
D
N
V
S
D
S
A
K
E
L
I
T
M
M
L
L
V
D
V
D
Q
R
F
S
A
V
Q
V
L
E
H
P
W
V
N
--------------------------------------------------------------------------------------------
21
Blastp_CBE
93.07
99%
-136
- C2 -
-
5JZJ
1
B:
[30-296]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
A
T
I
T
E
R
Y
K
V
G
R
T
I
G
D
G
N
F
A
V
V
K
E
C
V
E
R
S
T
A
R
E
Y
A
L
K
I
I
K
K
S
K
C
R
G
K
E
H
M
I
Q
N
E
V
S
I
L
R
R
V
K
H
P
N
I
V
L
L
I
E
E
M
D
V
P
T
E
L
Y
L
V
M
E
L
V
K
G
G
D
L
F
D
A
I
T
S
T
N
K
Y
T
E
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Y
L
H
S
L
N
I
V
H
R
D
I
K
P
E
N
L
L
V
Y
E
H
Q
D
G
S
K
S
L
K
L
G
D
F
G
L
A
T
I
V
D
G
P
L
Y
T
V
C
G
T
P
T
Y
V
A
P
E
I
I
A
E
T
G
Y
G
L
K
V
D
I
W
A
A
G
V
I
T
Y
I
L
L
C
G
F
P
P
F
R
------
E
V
L
F
D
Q
I
L
M
G
Q
V
D
F
P
S
P
Y
W
D
N
V
S
D
S
A
K
E
L
I
T
M
M
L
L
V
D
V
D
Q
R
F
S
A
V
Q
V
L
E
H
P
W
V
N
--------------------------------------------------------------------------------------------