@TOME V3
(Feb 2022)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : IRAK1_HUMAN: (2019-04-29 )
MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
Atome Classification :
(2 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MAGGPGPGEPAAPGAQ
H
F
L
YEV
P
P
W
V
M
C
R
F
Y
K
V
M
D
AL
E
P
A
D
W
C
Q
F
A
A
L
I
VRD
Q
T
E
L
R
L
C
E
RSGQR
T
A
S
V
L
W
P
W
INRNA
R
V
A
D
L
V
H
I
L
T
H
L
Q
L
L
R
ARD
I
I
TAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSS
A
S
T
FLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTKPGP
E
S
S
V
S
L
L
QGARPFPF
C
W
P
L
C
E
ISRGTHNF
S
E
ELKIGEG
G
F
G
C
V
Y
R
A
V
M
R
N
T
V
Y
A
V
K
R
L
KENADL
E
W
T
A
V
K
Q
S
F
L
T
E
V
E
Q
L
S
RFRHPN
I
V
D
F
A
G
Y
C
A
QN
G
F
Y
C
L
V
Y
G
FLPNGSL
E
D
R
L
H
CQTQACPPLS
W
P
Q
R
L
D
I
L
L
G
T
A
R
A
I
Q
F
L
HQDSPS
L
I
H
GDIKSS
N
V
L
LDERLTPKLG
D
F
G
L
A
R
F
S
R
FAGSSPSQ
S
S
M
V
A
R
T
Q
TVR
G
T
L
A
YL
P
E
E
Y
I
KTG
R
L
A
VDTDTF
S
F
G
V
V
V
L
E
T
L
AGQ
R
A
V
K
THG
A
R
T
K
Y
L
K
D
L
V
E
E
E
A
E
EA
G
V
A
L
R
S
T
Q
S
T
L
Q
AGLAADAWA
A
P
I
A
M
Q
I
Y
K
K
HLDPRPGPC
P
P
E
LGL
G
L
G
Q
L
A
C
C
C
L
H
R
R
AKRRP
P
M
T
Q
V
Y
E
R
L
E
K
L
Q
A
V
V
AGVPGHS
E
A
ASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGA
S
A
Q
A
A
E
Q
L
QRGPNQPVESDESL
G
G
L
S
A
A
L
R
SWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRP
T
A
V
E
G
L
ALGSSASSSSEP
P
Q
I
I
I
N
P
A
R
Q
K
M
V
Q
K
L
A
LYEDGA
L
D
S
L
Q
L
L
SSSSLPGLG
L
E
QDRQGPEESDEFQS
1
PsiBlast_PDB
99.22
99%
-117
- C1 -
-
6BFN
1
IRAK1_HUMAN
A:
[5-338]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
P
F
P
F
C
W
P
L
C
E
I
S
R
G
T
H
N
F
S
E
E
L
K
I
G
E
G
G
F
G
C
V
Y
R
A
V
M
R
N
T
V
Y
A
V
K
R
L
K
E
-----
W
T
A
V
K
Q
S
F
L
T
E
V
E
Q
L
S
R
F
R
H
P
N
I
V
D
F
A
G
Y
C
A
Q
N
G
F
Y
C
L
V
Y
G
F
L
P
N
G
S
L
E
D
R
L
H
C
Q
T
Q
A
C
P
P
L
S
W
P
Q
R
L
D
I
L
L
G
T
A
R
A
I
Q
F
L
H
Q
D
S
P
S
L
I
H
G
D
I
K
S
S
N
V
L
L
D
E
R
L
T
P
K
L
G
D
F
G
L
A
R
F
S
R
----------------
T
V
R
G
T
L
A
Y
L
P
E
E
Y
I
K
T
G
R
L
A
V
D
T
D
T
F
S
F
G
V
V
V
L
E
T
L
A
G
Q
R
A
V
K
T
H
G
A
R
T
K
Y
L
K
D
L
V
E
E
E
A
E
E
A
G
V
A
------------
A
A
D
A
W
A
A
P
I
A
M
Q
I
Y
K
K
H
L
D
P
R
P
G
P
C
P
P
E
L
G
L
G
L
G
Q
L
A
C
C
C
L
H
R
R
A
K
R
R
P
P
M
T
Q
V
Y
E
R
L
E
K
L
Q
A
V
V
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Blastp_CBE
95.53
99%
-118
- C1 -
-
6BFN
1
IRAK1_HUMAN
B:
[6-338]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
F
P
F
C
W
P
L
C
E
I
S
R
G
T
H
N
F
S
E
E
L
K
I
G
E
G
G
F
G
C
V
Y
R
A
V
M
R
N
T
V
Y
A
V
K
R
L
K
E
-----
W
T
A
V
K
Q
S
F
L
T
E
V
E
Q
L
S
R
F
R
H
P
N
I
V
D
F
A
G
Y
C
A
Q
N
G
F
Y
C
L
V
Y
G
F
L
P
N
G
S
L
E
D
R
L
H
C
Q
---
C
P
P
L
S
W
P
Q
R
L
D
I
L
L
G
T
A
R
A
I
Q
F
L
H
Q
D
S
P
S
L
I
H
G
D
I
K
S
S
N
V
L
L
D
E
R
L
T
P
K
L
G
D
F
G
L
A
R
F
S
R
----------------
T
V
R
G
T
L
A
Y
L
P
E
E
Y
I
K
T
G
R
L
A
V
D
T
D
T
F
S
F
G
V
V
V
L
E
T
L
A
G
Q
R
A
V
K
T
H
G
A
R
T
K
Y
L
K
D
L
V
E
E
E
A
E
E
A
G
V
A
---------------
A
W
A
A
P
I
A
M
Q
I
Y
K
K
H
L
D
P
R
P
G
P
C
P
P
E
L
G
L
G
L
G
Q
L
A
C
C
C
L
H
R
R
A
K
R
R
P
P
M
T
Q
V
Y
E
R
L
E
K
L
Q
A
V
V
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------