@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : KKCC1_HUMAN: (2019-04-30 )
MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDPPPRARAASVIPGSTSRLLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIESHHVAISDAEDCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNLLVKEGFGEGGKSPELPGVQEDEAAS
Atome Classification :
(6 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MEGGP
A
V
CCQD
P
R
A
E
L
V
E
R
V
A
A
I
D
V
T
H
LEEADGGPEPTRNGVDPPPRARAASVIPGSTSRLLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIES
H
H
V
AISD
A
E
D
C
V
Q
L
N
Q
Y
K
L
Q
S
E
IGKGA
Y
G
V
V
R
L
A
YNESE
D
R
H
Y
A
M
K
V
L
S
K
K
K
L
L
K
QYGFPRRPPPRGSQAAQGG
P
A
KQLL
P
L
E
R
V
Y
Q
E
I
A
I
L
K
K
LD
H
V
N
V
V
K
L
I
E
V
LDDPAEDN
L
Y
L
V
F
D
L
L
RKG
P
V
M
EVPCDKPF
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
RDIKPS
N
L
L
LGDDG
H
V
K
I
A
DFGVSNQFEGNDAQLSSTAGTPAFMA
P
E
AISDSGQSFSG
K
A
L
D
V
W
AT
G
V
T
L
Y
C
F
V
YGKCP
F
I
D
D
F
I
L
A
L
H
R
K
IKNEPVVFPEEP
E
I
S
E
E
L
K
D
L
I
L
K
M
LDKNPETRIGVPDIKLHPWVTKNGEEPLPS
E
E
EHCS
V
V
EV
T
E
E
E
V
K
N
S
V
R
LIP
S
W
T
T
V
I
L
V
K
S
M
L
R
KRSFGNPFE
P
Q
A
R
R
E
ERSMSAPG
N
L
L
V
KEGFGEGGKSPELPGVQEDEAAS
23
Blastp_CBE
85.85
99%
-120
- C1 -
-
6CD6
1
KKCC1_HUMAN
B:
[2-290]
--------------------------------------------------------------------------------------------------------------------------
M
Q
L
N
Q
Y
K
L
Q
S
E
I
G
K
G
A
Y
G
V
V
R
L
A
Y
N
E
S
E
D
R
H
Y
A
M
K
V
L
S
K
K
K
L
L
K
----------------------
Q
L
L
P
L
E
R
V
Y
Q
E
I
A
I
L
K
K
L
D
H
V
N
V
V
K
L
I
E
V
L
D
D
P
A
E
D
N
L
Y
L
V
F
D
L
L
R
K
G
P
V
M
E
V
P
C
D
K
P
F
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
R
D
I
K
P
S
N
L
L
L
G
D
D
G
H
V
K
I
A
D
F
G
V
S
N
Q
F
E
G
N
D
A
Q
L
S
S
T
A
G
T
P
A
F
M
A
P
E
A
I
S
-
S
G
Q
S
F
S
G
K
A
L
D
V
W
A
T
G
V
T
L
Y
C
F
V
Y
G
K
C
P
F
I
D
D
F
I
L
A
L
H
R
K
I
K
N
E
P
V
V
F
P
E
E
P
E
I
S
E
E
L
K
D
L
I
L
K
M
L
D
K
N
P
E
T
R
I
G
V
P
D
I
K
L
H
P
W
V
T
K
----------------------------------------------------------------------------------------------
22
Blastp_CBE
83.27
99%
-116
- C1 -
-
6CD6
1
KKCC1_HUMAN
C:
[3-290]
---------------------------------------------------------------------------------------------------------------------------
Q
L
N
Q
Y
K
L
Q
S
E
I
G
K
G
A
Y
G
V
V
R
L
A
Y
N
E
S
E
D
R
H
Y
A
M
K
V
L
S
K
K
K
L
L
K
----------------------
Q
L
L
P
L
E
R
V
Y
Q
E
I
A
I
L
K
K
L
D
H
V
N
V
V
K
L
I
E
V
L
D
D
P
A
E
D
N
L
Y
L
V
F
D
L
L
R
K
G
P
V
M
E
V
P
C
D
K
P
F
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
R
D
I
K
P
S
N
L
L
L
G
D
D
G
H
V
K
I
A
D
F
G
V
S
N
Q
F
E
G
N
D
A
Q
L
S
S
T
A
G
T
P
A
F
M
A
P
E
A
I
S
-
S
G
Q
S
F
S
G
K
A
L
D
V
W
A
T
G
V
T
L
Y
C
F
V
Y
G
K
C
P
F
I
D
D
F
I
L
A
L
H
R
K
I
K
N
E
P
V
V
F
P
E
E
P
E
I
S
E
E
L
K
D
L
I
L
K
M
L
D
K
N
P
E
T
R
I
G
V
P
D
I
K
L
H
P
W
V
T
K
----------------------------------------------------------------------------------------------
2
PsiBlast_PDB
81.86
99%
-118
- C1 -
-
6CD6
1
KKCC1_HUMAN
A:
[4-290]
----------------------------------------------------------------------------------------------------------------------------
L
N
Q
Y
K
L
Q
S
E
I
G
K
G
A
Y
G
V
V
R
L
A
Y
N
E
S
E
D
R
H
Y
A
M
K
V
L
S
K
K
K
L
L
K
Q
---------------------
Q
L
L
P
L
E
R
V
Y
Q
E
I
A
I
L
K
K
L
D
H
V
N
V
V
K
L
I
E
V
L
D
D
P
A
E
D
N
L
Y
L
V
F
D
L
L
R
K
G
P
V
M
E
V
P
C
D
K
P
F
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
R
D
I
K
P
S
N
L
L
L
G
D
D
G
H
V
K
I
A
D
F
G
V
S
N
Q
F
E
G
N
D
A
Q
L
S
S
T
A
G
T
P
A
F
M
A
P
E
A
I
S
--
G
Q
S
F
S
G
K
A
L
D
V
W
A
T
G
V
T
L
Y
C
F
V
Y
G
K
C
P
F
I
D
D
F
I
L
A
L
H
R
K
I
K
N
E
P
V
V
F
P
E
E
P
E
I
S
E
E
L
K
D
L
I
L
K
M
L
D
K
N
P
E
T
R
I
G
V
P
D
I
K
L
H
P
W
V
T
K
----------------------------------------------------------------------------------------------
21
Blastp_CBE
80.13
99%
-121
* C1 *
-
6CD6
1
KKCC1_HUMAN
D:
[2-290]
--------------------------------------------------------------------------------------------------------------------------
M
Q
L
N
Q
Y
K
L
Q
S
E
I
G
K
G
A
Y
G
V
V
R
L
A
Y
N
E
S
E
D
R
H
Y
A
M
K
V
L
S
K
K
K
L
L
K
----------------------
Q
L
L
P
L
E
R
V
Y
Q
E
I
A
I
L
K
K
L
D
H
V
N
V
V
K
L
I
E
V
L
D
D
P
A
E
D
N
L
Y
L
V
F
D
L
L
R
K
G
P
V
M
E
V
P
C
D
K
P
F
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
R
D
I
K
P
S
N
L
L
L
G
D
D
G
H
V
K
I
A
D
F
G
V
S
N
Q
F
E
G
N
D
A
Q
L
S
S
T
A
G
T
P
A
F
M
A
P
E
A
I
S
D
S
G
Q
S
F
S
G
K
A
L
D
V
W
A
T
G
V
T
L
Y
C
F
V
Y
G
K
C
P
F
I
D
D
F
I
L
A
L
H
R
K
I
K
N
E
P
V
V
F
P
E
E
P
E
I
S
E
E
L
K
D
L
I
L
K
M
L
D
K
N
P
E
T
R
I
G
V
P
D
I
K
L
H
P
W
V
T
K
----------------------------------------------------------------------------------------------
24
Blastp_CBE
74.04
99%
-129
- C1 -
-
6CCF
2
KKCC1_HUMAN
B:
[2-290]
--------------------------------------------------------------------------------------------------------------------------
M
Q
L
N
Q
Y
K
L
Q
S
E
I
G
K
G
A
Y
G
V
V
R
L
A
Y
N
E
S
E
D
R
H
Y
A
M
K
V
L
S
K
K
K
L
L
K
---------------------------
E
R
V
Y
Q
E
I
A
I
L
K
K
L
D
H
V
N
V
V
K
L
I
E
V
L
D
D
P
A
E
D
N
L
Y
L
V
F
D
L
L
R
K
G
P
V
M
E
V
P
C
D
K
P
F
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
R
D
I
K
P
S
N
L
L
L
G
D
D
G
H
V
K
I
A
D
F
G
V
S
N
Q
F
E
G
N
D
A
Q
L
S
S
T
A
G
T
P
A
F
M
A
P
E
A
I
S
D
S
G
Q
S
F
S
G
K
A
L
D
V
W
A
T
G
V
T
L
Y
C
F
V
Y
G
K
C
P
F
I
D
D
F
I
L
A
L
H
R
K
I
K
N
E
P
V
V
F
P
E
E
P
E
I
S
E
E
L
K
D
L
I
L
K
M
L
D
K
N
P
E
T
R
I
G
V
P
D
I
K
L
H
P
W
V
T
K
----------------------------------------------------------------------------------------------
1
PsiBlast_PDB
68.70
99%
-128
- C1 -
-
6CCF
2
KKCC1_HUMAN
A:
[2-290]
--------------------------------------------------------------------------------------------------------------------------
M
Q
L
N
Q
Y
K
L
Q
S
E
I
G
K
G
A
Y
G
V
V
R
L
A
Y
N
E
S
E
D
R
H
Y
A
M
K
V
L
S
K
K
K
-----------------------------
L
E
R
V
Y
Q
E
I
A
I
L
K
K
L
D
H
V
N
V
V
K
L
I
E
V
L
D
D
P
A
E
D
N
L
Y
L
V
F
D
L
L
R
K
G
P
V
M
E
V
P
C
D
K
P
F
S
E
E
Q
A
R
L
Y
L
R
D
V
I
L
G
L
E
Y
L
H
C
Q
K
I
V
H
R
D
I
K
P
S
N
L
L
L
G
D
D
G
H
V
K
I
A
D
F
G
V
S
N
Q
F
E
G
N
D
A
Q
L
S
S
T
A
G
T
P
A
F
M
A
P
E
A
I
S
D
S
G
Q
S
F
S
G
K
A
L
D
V
W
A
T
G
V
T
L
Y
C
F
V
Y
G
K
C
P
F
I
D
D
F
I
L
A
L
H
R
K
I
K
N
E
P
V
V
F
P
E
E
P
E
I
S
E
E
L
K
D
L
I
L
K
M
L
D
K
N
P
E
T
R
I
G
V
P
D
I
K
L
H
P
W
V
T
K
----------------------------------------------------------------------------------------------