@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : M3K8_HUMAN: (2019-05-01 )
MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERSKSLLLSGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYGQRPQESGILLNMVITPQNGRYQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG
Atome Classification :
(8 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MEYMSTGSD
N
K
E
E
I
D
L
L
I
K
HL
N
V
S
D
V
I
D
I
M
E
N
L
YASEEPAVYE
P
S
L
M
T
M
CQDSNQ
N
D
E
R
S
K
S
LLLSGQEVP
W
L
S
SVRYG
T
V
E
D
L
L
A
F
A
N
H
I
S
N
T
A
K
H
F
YGQRPQES
G
I
L
L
N
M
V
I
TPQNG
R
Y
Q
IDS
D
V
L
L
I
P
W
K
L
T
Y
R
NI
G
S
D
FIPRGAFG
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
KLIPVDQFKPSD
V
E
I
Q
A
C
FRHE
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
EAGE
G
G
S
V
L
E
K
L
E
SCGPM
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
HHDIKPS
N
I
V
F
M
ST
K
A
V
L
V
DFGL
S
V
Q
M
TEDVYFPKDLRG
T
E
I
Y
MSP
E
V
I
L
CRGHSTK
A
D
I
Y
S
L
G
A
T
L
I
H
MQTGT
P
P
W
V
K
RYPRSAYP
S
Y
L
Y
I
I
HKQAP
P
L
E
D
I
A
DDC
S
P
G
M
R
E
L
I
E
A
S
L
ERNPNHR
P
R
A
A
D
L
L
K
H
EALNPPRED
Q
P
R
C
Q
S
L
D
S
A
L
L
E
R
K
R
L
L
S
R
K
ELELPENIADSSCTGS
T
E
E
S
E
M
L
K
R
Q
R
S
L
Y
I
D
L
G
A
L
A
G
Y
F
N
LVRGPPTLEYG
3
PsiBlast_PDB
97.85
100%
-96
- C1 -
-
5IU2
1
M3K8_HUMAN
A:
[10-326]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
I
S
N
----
F
Y
G
Q
R
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
N
-
G
S
D
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
R
S
A
Y
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
------------------------------------------------------------------------------
21
Blastp_CBE
96.38
100%
-96
- C1 -
-
5IU2
1
M3K8_HUMAN
B:
[10-326]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
I
S
N
---
H
F
Y
G
Q
R
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
N
-
G
S
D
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
R
S
A
Y
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
------------------------------------------------------------------------------
22
Blastp_CBE
94.26
100%
-97
- C1 -
-
4Y85
1
M3K8_HUMAN
C:
[10-327]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
I
S
----------
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
-----
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
R
S
A
Y
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
P
-----------------------------------------------------------------------------
23
Blastp_CBE
94.07
100%
-96
- C1 -
-
4Y85
1
M3K8_HUMAN
B:
[10-327]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
I
S
N
---------
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
N
I
---
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
R
S
A
Y
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
P
-----------------------------------------------------------------------------
2
PsiBlast_PDB
93.26
100%
-94
* C1 *
-
4Y85
1
M3K8_HUMAN
A:
[10-327]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
I
S
N
T
--------
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
N
I
---
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
R
S
A
Y
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
P
-----------------------------------------------------------------------------
25
Blastp_CBE
89.79
100%
-100
- C1 -
-
4Y83
1
M3K8_HUMAN
B:
[10-327]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
I
S
----------
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
N
I
G
S
D
F
I
P
R
--
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
----
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
P
-----------------------------------------------------------------------------
1
PsiBlast_PDB
87.13
100%
-97
- C1 -
-
4Y83
1
M3K8_HUMAN
A:
[10-326]
------------------------------------------------------------------------
L
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
-----------
R
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
L
I
P
W
K
L
T
Y
R
N
I
G
S
D
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
-------
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
------------------------------------------------------------------------------
24
Blastp_CBE
82.94
100%
-99
- C1 -
-
4Y83
1
M3K8_HUMAN
C:
[11-326]
-------------------------------------------------------------------------
S
S
V
R
Y
G
T
V
E
D
L
L
A
F
A
N
H
------------
P
Q
E
S
G
I
L
L
N
M
V
I
T
P
Q
N
G
R
Y
Q
I
D
S
D
V
L
-
I
P
W
K
L
T
Y
R
N
I
G
S
D
F
I
P
R
---
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
F
K
P
S
D
V
E
I
Q
A
C
F
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
G
E
T
V
H
L
F
M
E
A
G
E
G
G
S
V
L
E
K
L
E
S
C
G
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
M
S
T
K
A
V
L
V
D
F
G
L
S
V
Q
M
-
E
D
V
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
Y
P
---
Y
P
S
Y
L
Y
I
I
H
K
Q
A
P
P
L
E
D
I
---
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
R
A
A
D
L
L
K
H
E
A
L
N
------------------------------------------------------------------------------