@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MK09_HUMAN: (2019-05-02 )
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR
Atome Classification :
(3 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSDSKCDS
Q
F
Y
S
V
Q
VAD
S
T
F
T
V
L
K
R
Y
Q
Q
LKPIGSGAQ
G
I
V
C
A
A
F
D
T
V
L
G
I
N
V
A
V
K
K
LSRPFQN
Q
T
H
A
K
R
A
Y
R
E
L
V
L
L
K
CV
N
H
K
N
I
I
S
L
L
N
VFT
P
Q
K
T
L
E
E
F
Q
D
V
Y
L
V
M
E
L
M
D
A
N
L
C
Q
V
I
H
M
EL
D
H
E
R
M
S
Y
L
L
Y
Q
M
L
C
G
I
K
H
L
H
SAG
I
I
HRDLKPS
N
I
V
VKSD
C
T
L
K
I
L
D
FGL
A
R
T
A
C
T
NFMM
T
P
Y
V
V
T
R
YYRA
P
E
V
I
L
GMGYKENV
D
I
W
S
V
G
C
I
M
G
E
L
V
K
G
C
V
I
FQGTD
H
I
D
Q
W
N
K
V
I
E
QLGT
P
S
A
E
F
M
K
K
L
Q
P
T
V
R
N
Y
V
ENRPKYPGI
K
F
E
E
LFPDWIFPSESE
R
D
KI
K
T
S
Q
A
R
D
L
L
S
K
M
L
V
IDPDKRI
S
V
D
E
A
LRH
P
Y
I
T
V
W
YDPAEAEAPPP
Q
I
Y
D
A
Q
L
E
E
R
E
H
A
I
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
E
E
RSKNGVVKDQPSDAAVSSNATPSQSSSIN
D
I
S
SMST
E
Q
TLASDTDSSLDASTGPLEGCR
1
PsiBlast_PDB
77.14
97%
-136
- C1 -
-
3NPC
1
MK09_HUMAN
A:
[7-363]
------
D
N
Q
F
Y
S
V
E
V
A
D
S
T
F
T
V
L
K
R
Y
Q
Q
L
K
P
I
G
S
G
A
Q
G
I
V
C
A
A
F
D
T
V
L
G
I
N
V
A
V
K
K
L
S
R
P
F
Q
N
Q
T
H
A
K
R
A
Y
R
E
L
V
L
L
K
C
V
N
H
K
N
I
I
S
L
L
N
V
F
T
P
Q
K
T
L
E
E
F
Q
D
V
Y
L
V
M
E
L
M
D
A
N
L
C
Q
V
I
H
M
E
L
D
H
E
R
M
S
Y
L
L
Y
Q
M
L
C
G
I
K
H
L
H
S
A
G
I
I
H
R
D
L
K
P
S
N
I
V
V
K
S
D
C
T
L
K
I
L
D
F
G
L
A
R
T
A
C
T
N
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
A
P
E
V
I
L
G
M
G
Y
A
A
N
V
D
I
W
S
V
G
C
I
M
G
E
L
V
K
G
C
V
I
F
Q
G
T
D
H
I
D
Q
W
N
K
V
I
E
Q
L
G
T
P
S
A
E
F
M
A
A
L
Q
P
T
V
R
N
Y
V
E
N
R
P
K
Y
P
G
I
K
F
E
E
L
F
P
D
W
I
F
P
S
E
S
E
R
D
K
I
K
T
S
Q
A
R
D
L
L
S
K
M
L
V
I
D
P
D
K
R
I
S
V
D
E
A
L
R
H
P
Y
I
T
V
W
Y
D
P
A
E
A
E
A
P
P
P
Q
I
Y
D
A
Q
L
E
E
R
E
H
A
I
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
-------------------------------------------------------------
4
PsiBlast_PDB
75.44
97%
-150
- C1 -
-
3E7O
1
MK09_HUMAN
A:
[7-359]
--------
Q
F
Y
S
V
Q
V
A
D
S
T
F
T
V
L
K
R
Y
Q
Q
L
K
P
I
G
S
G
A
Q
G
I
V
C
A
A
F
D
T
V
L
G
I
N
V
A
V
K
K
L
S
R
P
F
Q
N
Q
T
H
A
K
R
A
Y
R
E
L
V
L
L
K
C
V
N
H
K
N
I
I
S
L
L
N
V
F
T
P
Q
K
T
L
E
E
F
Q
D
V
Y
L
V
M
E
L
M
D
A
N
L
C
Q
V
I
H
M
E
L
D
H
E
R
M
S
Y
L
L
Y
Q
M
L
C
G
I
K
H
L
H
S
A
G
I
I
H
R
D
L
K
P
S
N
I
V
V
K
S
D
C
T
L
K
I
L
D
F
G
L
A
R
T
A
S
T
N
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
A
P
E
V
I
L
G
M
G
Y
K
E
N
V
D
I
W
S
V
G
C
I
M
G
E
L
V
K
G
S
V
I
F
Q
G
T
D
H
I
D
Q
W
N
K
V
I
E
Q
L
G
T
P
S
A
E
F
M
A
A
L
Q
P
T
V
R
N
Y
V
E
N
R
P
A
Y
P
G
I
A
F
E
E
L
F
P
D
W
I
F
P
S
E
--
R
D
K
I
K
T
S
Q
A
R
D
L
L
S
K
M
L
V
I
D
P
D
K
R
I
S
V
D
E
A
L
R
H
P
Y
I
T
V
W
Y
D
P
A
E
A
E
A
P
P
P
Q
I
---------
H
A
I
E
E
W
K
E
L
I
Y
K
E
V
M
---------------------------------------------------------------
21
Blastp_CBE
74.73
98%
-136
- C1 -
-
3NPC
1
MK09_HUMAN
B:
[8-363]
-------
N
Q
F
Y
S
V
E
V
A
D
S
T
F
T
V
L
K
R
Y
Q
Q
L
K
P
I
G
S
G
A
Q
G
I
V
C
A
A
F
D
T
V
L
G
I
N
V
A
V
K
K
L
S
R
P
F
Q
N
Q
T
H
A
K
R
A
Y
R
E
L
V
L
L
K
C
V
N
H
K
N
I
I
S
L
L
N
V
F
T
P
Q
K
T
L
E
E
F
Q
D
V
Y
L
V
M
E
L
M
D
A
N
L
C
Q
V
I
H
M
E
L
D
H
E
R
M
S
Y
L
L
Y
Q
M
L
C
G
I
K
H
L
H
S
A
G
I
I
H
R
D
L
K
P
S
N
I
V
V
K
S
D
C
T
L
K
I
L
D
F
G
L
A
R
T
A
C
T
N
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
A
P
E
V
I
L
G
M
G
Y
A
A
N
V
D
I
W
S
V
G
C
I
M
G
E
L
V
K
G
C
V
I
F
Q
G
T
D
H
I
D
Q
W
N
K
V
I
E
Q
L
G
T
P
S
A
E
F
M
A
A
L
Q
P
T
V
R
N
Y
V
E
N
R
P
K
Y
P
G
I
K
F
E
E
L
F
P
D
W
I
F
P
S
E
S
E
R
D
K
I
K
T
S
Q
A
R
D
L
L
S
K
M
L
V
I
D
P
D
K
R
I
S
V
D
E
A
L
R
H
P
Y
I
T
V
W
Y
D
P
A
E
A
E
A
P
P
P
Q
I
Y
D
A
Q
L
E
E
R
E
H
A
I
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
-------------------------------------------------------------