@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MRCKB_HUMAN: (2019-05-02 )
MSAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELEALRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLPDFQDSIFEYFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARPPQRPSAVPLPTTQALALAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVTASLLGAPSKTSSLLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLEAYDSSLPLIKAILTAAIVDADRIAVGLEEGLYVIEVTRDVIVRAADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSLDGAEGSFDIKLPETKGCQLMATATLKRNSGTCLFVAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDRLCVGYPSGFCLLSIQGDGQPLNLVNPNDPSLAFLSQQSFDALCAVELESEEYLLCFSHMGLYVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSEGTLNLLNCEPPRLIYFKSKFSGAVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPSQEERPGPAPTNLARQPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT
Atome Classification :
(8 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSA
K
V
R
L
K
K
L
E
Q
L
L
LDGPWRNESAL
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
EC
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
GRGAFG
E
V
A
V
V
K
MKNT
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
EER
D
V
L
VNGD
C
Q
W
I
T
A
L
H
Y
AFQDEN
H
L
Y
L
V
M
DYYVG
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
RDIKPD
N
V
L
L
DVNG
H
I
R
L
ADF
G
S
C
L
KMNDDG
T
V
QS
S
V
AVGTPDYI
S
P
E
I
L
Q
A
M
E
D
G
M
GKYGPEC
D
W
W
S
L
G
V
C
M
Y
E
M
LYGETP
F
Y
A
E
S
L
V
E
T
Y
G
K
IM
N
H
E
E
R
FQFPSHV
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
RLGQN
G
I
E
D
F
K
K
H
A
FFEGL
N
W
E
NIRNLEAPYIPDVSSPSDTSNFDV
D
D
D
V
LRNTEILPPGSHTGFSG
L
H
L
P
F
I
G
F
T
FT
T
E
S
C
FSD
R
G
S
L
K
S
I
M
Q
SNTLT
K
D
E
D
V
Q
R
D
L
E
H
S
L
Q
M
E
A
Y
E
R
R
I
R
R
L
E
Q
E
K
L
E
L
S
R
K
L
Q
E
S
T
Q
T
V
Q
S
L
HGSSRALSNSN
R
D
K
E
I
K
K
L
N
E
E
I
E
R
L
K
N
KIA
D
S
N
R
L
E
R
Q
L
E
D
T
V
A
L
R
Q
ERE
D
S
T
Q
R
L
R
G
L
E
K
Q
H
R
V
V
R
Q
E
K
E
E
L
H
K
Q
L
V
E
A
S
E
R
L
K
S
Q
A
K
E
L
K
D
A
H
Q
Q
R
K
L
A
L
Q
E
F
S
E
L
N
E
R
M
A
E
L
R
A
Q
K
Q
K
V
S
R
Q
L
R
D
K
E
E
E
M
E
V
A
T
Q
K
V
D
A
M
R
Q
E
M
R
R
A
E
K
L
R
K
E
L
E
A
Q
L
D
D
A
V
A
E
A
S
K
E
R
K
L
R
E
H
S
E
N
F
C
K
Q
M
E
S
E
L
E
A
L
K
VKQGGRGAGA
T
L
E
H
Q
Q
E
I
S
K
I
K
S
E
L
E
K
K
V
L
F
Y
E
E
E
L
V
R
R
E
A
S
H
V
L
E
V
K
N
V
K
K
E
VHDSE
S
H
Q
L
A
L
Q
K
E
I
L
M
L
K
D
K
L
E
K
S
K
R
E
R
H
N
E
M
E
E
A
V
G
T
I
K
D
K
Y
E
R
E
R
A
M
LFDENKKLTA
E
N
E
K
L
C
S
F
V
D
K
L
TAQN
R
Q
L
E
D
E
L
Q
D
L
A
A
K
K
E
S
V
A
H
W
E
A
Q
I
A
E
I
I
Q
W
VSDE
K
D
A
R
G
Y
L
Q
A
L
A
S
K
M
T
E
E
L
E
A
L
R
SSSLGSR
T
L
D
P
L
W
K
V
R
R
SQKL
D
M
S
A
R
L
E
L
Q
S
A
L
E
A
E
I
R
A
K
Q
L
V
Q
E
E
L
R
K
V
KDAN
L
T
L
ESKLKDSEAK
N
R
E
L
L
E
E
M
E
I
L
K
K
K
M
E
E
K
FRADTGLKLPD
F
Q
D
S
I
F
E
Y
FNTAPLAH
D
L
T
FRTSSASEQETQAPKPEASPSMSVAA
S
E
Q
Q
E
D
MARPPQRPSAVPLPTT
Q
A
L
ALAGPKPKA
H
Q
F
S
IKSFSSPTQ
C
S
H
C
T
S
L
M
V
G
L
I
RQGY
A
C
E
V
C
S
F
A
C
H
V
S
CKDGAPQVCPIPPEQSKRPLGV
D
V
Q
RGIGTAYKGHVKVPKPT
G
V
K
K
G
W
Q
R
A
Y
A
V
V
C
D
C
K
L
F
L
Y
DLPEGKSTQP
G
V
I
A
S
Q
V
L
DLRDDEF
S
V
S
S
V
L
A
S
D
V
I
H
A
T
RRDI
P
C
I
F
R
V
T
A
S
L
LGAPSKT
S
S
L
L
I
L
TENEN
E
K
R
K
W
V
G
I
L
E
G
L
Q
S
I
L
H
K
N
R
LRNQ
V
V
H
V
P
L
E
AYDSS
L
P
L
I
K
A
I
L
T
A
A
I
V
D
A
D
R
I
A
V
G
L
EE
G
L
Y
V
I
E
V
T
R
D
V
I
V
R
A
ADC
K
K
V
H
Q
I
ELAPR
E
K
I
V
I
L
L
CGRN
H
H
V
H
L
Y
PWSSLDGAEG
S
F
D
I
KLPETKG
C
Q
L
M
A
T
A
T
L
KRNSGT
C
L
F
V
A
V
K
R
L
I
L
C
Y
EIQRT
K
P
F
H
R
K
F
N
E
IVAPG
S
V
Q
C
L
A
V
L
R
D
R
LCVGYPS
G
F
C
L
L
S
IQGDGQ
P
L
N
L
VNPNDP
S
L
A
F
L
SQQSF
D
A
L
C
A
V
E
LESE
E
Y
L
L
C
F
S
HM
G
L
Y
VDPQG
R
R
A
R
A
Q
E
LMWPAAPVACSCSP
T
H
V
T
V
Y
SEYG
V
D
V
F
D
V
R
T
M
E
W
V
Q
T
IGLRRIRPLNSEG
T
L
N
L
LNCEP
P
R
L
I
Y
F
KSKFS
G
A
V
L
NVPDTSD
N
S
K
K
Q
M
L
R
T
RSKR
R
F
V
F
KVP
E
E
E
R
L
Q
Q
R
R
E
M
LR
D
P
E
L
R
S
K
MISNPTNFNHVAHMGPG
D
G
M
Q
V
L
M
DLPLSAVPPSQEERPGPAPTNLARQPPSRNK
P
Y
I
SWPSSGGSEP
S
V
T
V
PLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT
5
PsiBlast_PDB
94.98
100%
-111
- C1 -
-
5OTF
3
MRCKB_HUMAN
A:
[4-419]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
--------
E
I
L
P
P
G
S
H
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
92.89
100%
-117
- C1 -
-
5OTE
2
MRCKB_HUMAN
A:
[4-419]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
--
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
----------
I
L
P
P
G
S
H
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
92.62
100%
-117
- C1 -
-
4UAK
2
MRCKB_HUMAN
A:
[4-419]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
---------------
S
H
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
90.20
100%
-118
- C1 -
-
4UAL
2
MRCKB_HUMAN
A:
[4-419]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
---
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
--
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
---------
I
L
P
P
--
H
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
84.63
100%
-107
- C1 -
-
3TKU
3
MRCKB_HUMAN
A:
[18-431]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
-------------------
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Blastp_CBE
83.81
100%
-111
- C1 -
-
3TKU
3
MRCKB_HUMAN
B:
[18-431]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
-------------------
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
83.09
100%
-111
- C1 -
-
3QFV
2
MRCKB_HUMAN
A:
[2-415]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
-------------------
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Blastp_CBE
81.96
100%
-111
- C1 -
-
3QFV
3
MRCKB_HUMAN
B:
[2-415]
-
S
A
K
V
R
L
K
K
L
E
Q
L
L
L
D
G
P
W
R
N
E
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
T
E
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
R
F
Q
F
P
S
H
V
T
D
V
S
E
E
A
K
D
L
I
Q
R
L
I
C
S
R
E
R
R
L
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
------------------
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------