@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ROCK2_HUMAN: (2019-05-03 )
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS
Atome Classification :
(7 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSRPPPTGKMPGAPETAPGDGAG
A
S
R
Q
R
K
L
E
A
L
I
RDPRSPI
N
V
E
S
L
L
D
G
L
N
S
L
V
LDLD
F
P
A
LRKNK
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
RGLQMKAED
Y
D
V
V
K
V
I
GRGAFG
E
V
Q
L
V
R
H
KASQ
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
KRSDS
A
F
F
W
EER
D
I
M
AFANS
P
W
V
V
Q
L
F
Y
A
FQDD
R
Y
L
Y
M
V
M
E
YMPG
G
D
L
V
N
L
M
SNYDV
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
IHRDVKPD
N
M
L
LDKHG
H
L
K
L
ADFGTCMKMDET
G
M
V
H
CDTAVGTPDYI
S
P
E
V
L
KSQGGDGFYGREC
D
W
W
S
V
G
V
F
L
Y
E
M
L
VGDTPF
Y
A
D
S
L
V
G
T
Y
S
K
I
M
DHKNSLCFPE
D
A
E
I
S
K
H
A
K
N
L
I
C
AFLTDR
E
V
RLGR
N
G
V
E
E
I
R
QHPFFKNDQWHWD
N
I
R
E
TAAPVV
P
E
L
SSDIDSSNFDDIEDDKGDVETFPI
P
K
A
F
VGNQLPFI
G
F
T
Y
Y
R
ENLLLSDSPSCRE
T
D
S
I
Q
SRKN
E
E
S
Q
E
I
Q
K
K
L
Y
T
L
E
E
H
L
S
N
E
M
Q
A
K
E
E
L
E
Q
K
C
K
S
V
N
T
R
L
E
K
T
A
K
E
L
E
E
E
I
T
L
R
K
S
V
E
S
A
L
R
Q
L
E
R
E
K
A
L
L
Q
HKN
A
E
Y
Q
RKADH
E
A
D
K
KR
N
L
E
N
D
V
N
S
L
K
D
Q
L
E
D
L
K
KRNQNSQI
S
T
E
K
V
N
Q
L
Q
R
Q
L
D
E
T
N
A
L
L
RTES
D
T
A
A
R
L
R
K
TQ
A
E
S
S
K
Q
I
Q
Q
L
ESNNRDLQ
D
K
N
C
L
L
E
T
A
K
L
K
L
E
K
E
F
I
N
L
Q
S
A
L
E
S
E
RRDRTH
G
S
E
I
I
N
D
L
Q
G
RICG
L
E
E
DLKN
G
K
I
L
L
A
K
V
E
L
E
K
R
Q
L
Q
E
R
F
T
D
L
E
K
EKSN
M
E
I
D
M
T
Y
Q
L
K
V
I
Q
Q
S
L
E
Q
E
E
A
E
H
K
A
T
K
A
RLA
D
K
N
K
I
Y
E
S
I
E
E
A
K
S
E
A
M
K
E
M
E
K
K
L
L
E
E
R
T
L
K
Q
K
V
E
N
L
L
L
E
A
E
K
RCSLLDC
D
L
K
Q
S
Q
Q
K
I
N
E
L
L
K
Q
K
D
V
L
N
E
D
V
R
N
L
T
L
K
I
E
Q
E
T
Q
K
RCLTQNDL
K
M
Q
T
Q
QV
N
T
L
K
M
S
E
K
Q
L
K
Q
ENNH
L
M
E
M
K
MN
L
E
K
Q
N
A
E
L
R
K
E
RQDADG
Q
M
K
E
L
Q
D
Q
L
E
A
E
Q
Y
F
S
T
L
Y
K
T
Q
V
R
E
L
K
E
E
C
E
E
K
T
K
L
G
K
E
L
Q
Q
K
K
Q
E
L
Q
D
E
R
D
S
L
A
A
Q
L
E
I
T
L
TKA
D
S
E
Q
L
A
R
S
I
A
E
E
Q
Y
S
D
L
E
K
E
K
I
M
K
E
L
E
I
K
E
M
M
A
R
H
K
Q
E
L
T
EKDAT
I
A
S
L
E
E
TN
R
T
L
T
S
D
V
A
N
L
A
N
E
K
E
E
L
N
N
K
L
K
D
V
Q
E
Q
L
S
R
L
K
D
EEI
S
A
A
A
I
K
A
Q
F
E
K
Q
L
L
T
E
RT
L
K
T
Q
A
V
N
K
L
A
E
I
MNRKEPVKRGND
T
D
V
R
R
K
E
KEN
R
K
L
H
M
E
L
K
S
E
R
E
K
L
T
Q
Q
M
I
K
Y
Q
K
E
L
N
E
M
Q
A
Q
IAEE
S
Q
I
R
I
E
L
Q
M
T
LDSKD
S
D
I
E
Q
L
R
S
Q
L
Q
A
L
HIGLDSSSIGSGPGDAEADDGF
P
E
S
R
L
E
G
W
LSLPVRNNT
K
K
F
G
W
V
K
K
Y
V
I
V
SS
K
K
I
L
F
YDSEQDKEQSNP
Y
M
V
L
D
I
D
K
L
F
HVRPVT
Q
T
D
V
YRA
D
A
K
E
I
P
R
I
F
Q
I
L
YANEGESKKEQEFPVEPVGEKS
N
Y
I
C
HKGHEF
I
P
T
L
YHFPT
N
C
E
A
C
M
K
P
L
W
H
MFKPPP
A
L
E
C
R
R
C
H
I
K
CHKDHMD
K
K
E
E
IIA
P
C
K
V
Y
Y
D
ISTAK
N
L
L
L
L
ANS
T
E
E
Q
Q
K
W
V
S
R
L
V
K
KIPKKPPAPDPFARSSPRT
S
M
K
I
QQNQSIRRP
S
R
QLAPNKPS
1
PsiBlast_PDB
78.56
99%
-116
- C1 -
-
4L6Q
1
ROCK2_HUMAN
A:
[12-402]
--------------------------
Q
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
G
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
R
Q
H
P
F
F
K
N
D
Q
W
H
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
E
D
D
---
V
E
T
F
P
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
76.03
98%
-116
- C1 -
-
2F2U
1
ROCK2_BOVIN
A:
[12-402]
--------------------------
Q
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
G
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
K
Q
H
P
F
F
K
N
D
Q
W
N
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
E
-----
V
E
T
F
P
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Blastp_CBE
74.04
99%
-109
- C1 -
-
4L6Q
1
ROCK2_HUMAN
B:
[12-402]
--------------------------
Q
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
G
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
R
Q
H
P
F
F
K
N
D
Q
W
H
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
E
D
D
---
V
E
T
F
P
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Blastp_CBE
57.78
98%
-111
- C1 -
-
2F2U
1
ROCK2_BOVIN
B:
[12-402]
--------------------------
Q
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
G
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
K
Q
H
P
F
F
K
N
D
Q
W
N
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
--------
T
F
P
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
56.54
100%
-111
- C1 -
-
6ED6
1
ROCK2_HUMAN
A:
[25-413]
--------------------------
Q
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
----
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
R
Q
H
P
F
F
K
N
D
Q
W
H
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
E
-------
T
F
P
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
49.56
98%
-102
- C1 -
-
2H9V
1
ROCK2_BOVIN
A:
[10-402]
------------------------
S
R
Q
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
G
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
K
Q
H
P
F
F
K
N
D
Q
W
N
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
E
----------
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Blastp_CBE
40.68
100%
-118
- C1 -
-
6ED6
1
ROCK2_HUMAN
B:
[26-414]
---------------------------
R
K
L
E
A
L
I
R
D
P
R
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
S
Q
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
------------
G
T
P
D
Y
I
S
P
E
V
L
K
S
------
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
S
L
C
F
P
E
D
A
E
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
L
G
R
N
G
V
E
E
I
R
Q
H
P
F
F
K
N
D
Q
W
H
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
E
-------
T
F
P
I
P
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------