@TOME V3
(Feb 2022)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Modeled complexes Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor model: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : TYK2_HUMAN: (2019-05-05 )
MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC

Atome Classification :

(21 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

0MX_A_2(4E1Z)

[Raw transfer]



5U4_A_2(5F20)

[Raw transfer]



MI1_A_2(3LXN)

[Raw transfer]



G5D_A_2(6DBK)

[Raw transfer]



0MY_A_2(4E20)

[Raw transfer]



5U3_A_2(5F1Z)

[Raw transfer]



ADP_A_2(4GVJ)

[Raw transfer]



2TT_A_3(4OLI)
TYK2_HUMAN
[Raw transfer]



G4J_A_2(6DBM)

[Raw transfer]



GOL_B_13(5C03)

[Raw transfer]



0X5_A_2(4GIH)

[Raw transfer]



0XH_A_2(4GJ2)

[Raw transfer]



9ZS_A_2(5WAL)

[Raw transfer]



0XP_A_2(4GJ3)

[Raw transfer]



0X6_A_2(4GII)

[Raw transfer]



IZA_A_2(3LXP)

[Raw transfer]



2YK_A_2(4PY1)

[Raw transfer]



IZA_A_2(3NZ0)

[Raw transfer]



9T6_A_2(6AAM)

[Raw transfer]



0X2_A_7(4GFO)

[Raw transfer]



TZ1_A_2(3NYX)

[Raw transfer]
1 PsiBlast_PDB 84.2498%-109 - C2 -4OLI 6.3 TYK2_HUMAN
6 PsiBlast_PDB 32.0499%-136 * C2 *3NZ0 8.1
14 PsiBlast_PDB 31.9397%-139 - C2 -3LXP 8.2
8 PsiBlast_PDB 31.2598%-148 - C2 -4GFO 4.8
28 Blastp_CBE 30.8891%-138 - C2 -4E1Z 9.3
7 PsiBlast_PDB 30.5898%-142 - C2 -3NYX 9.2
26 Blastp_CBE 30.3998%-130 - C2 -4GJ2 6.4
25 Blastp_CBE 30.3198%-131 - C2 -4GJ3 6.8
13 PsiBlast_PDB 30.1397%-136 - C2 -3LXN 6.3
29 Blastp_CBE 30.0891%-146 - C2 -4E20 7.5
27 Blastp_CBE 30.0498%-130 - C2 -4GIH 6.3
20 PsiBlast_PDB 29.3997%-131 - C2 -4GII 6.8
9 PsiBlast_PDB 29.3999%-133 - C2 -5F1Z 7.0
24 Blastp_CBE 29.1698%-130 - C2 -5WAL 6.3
19 PsiBlast_PDB 28.4297%-129 - C2 -4GVJ 6.4
16 PsiBlast_PDB 27.5297%-125 - C2 -4PY1 6.6
17 PsiBlast_PDB 27.2897%-125 - C2 -6DBK 7.2
15 PsiBlast_PDB 27.0397%-136 - C2 -6AAM 6.2
10 PsiBlast_PDB 26.1299%-137 - C2 -5F20 6.2
18 PsiBlast_PDB 25.6597%-130 - C2 -6DBM 8.0
21 Blastp_CBE 13.80100%-100 - C2 -5C03 3.0