TITO

Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)

Input alignment information:

Query sequence

MGDSRDSRSPDSSSVSSPPSGQRSPPLAPSAAAMTSLPPITSAVNSPISSMGSPFSVISSSLGSPCLPGTPSVGYGPISSPQINSTVSMSGLHAVSSSDDVKPPFGLKPLSSHSPGPMVSQKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLSYTCRDNKDCLVDKRQRNRCQYCRYQKCLAMGMKREVVQDERQRSVQEERQRNKERDGEVESSSAANEEMPVEKILEAEMAVEQKTELHADGSSGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELSLDDQVILLRAGWNELLIASFSHRSITVKDGILLATGLHVHRNSAHSAGVGAIFDRESAHNAEVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIILFNPDAKGLSSPSEVELLREKVYASLEAYCKQRYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLT

4N8R Chain:B ((43-240))

---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGA--------------IFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP----

General information:

TITO was launched using:	RESULT:
Template: 4N8R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output	Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 755 -120404 -159.48 -608.10 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.74 3D Compatibility (PKB) : -159.48 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.258

(partial model without unconserved sides chains):
PDB file : Tito_4N8R.pdb:

(Unconserved sides chains are recalculated) :
Sequence: align-4n8r-query.scw
PDB file : Tito_Scwrl_4N8R.pdb: