@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MOT7_HUMAN: (2015-12-08 )
MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV
Atome Classification :
(20 SA)
------------.........10........20..-----......30-........40.......---.50..-..---.---...60........70....----....80----.......-..90......---..100......-----------------.110-.---.--------..-..---..-.120.......130-----...----....140.------.-.----.-...150....-.....160.......170------...--------------------------.--------..-.180.......190.......200.....-----..210-.......220.......230.......240.......---------------250.......260.......270.......280....-...290.......300....--...310----.....-..320........330.......340.......350...---..----..360..-.....370..--....--.380......------------------------.390.......400...------------------------.-.-.-.410.......420...-.-...430..-.....440.......450.......460.......470.......480.-------------......490.......500......------.510.......520.---------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------M
T
Q
N
K
L
K
LCSKAN
V
Y
T
EVPDGG
W
-----
G
W
A
V
A
V
S
F
-
F
F
V
E
V
F
T
Y
G
I
I
K
T
F
G
V
F
---
F
N
D
L
M
-
D
S
---F---NESN
S
R
I
S
W
I
I
S
I
C
V
F
V
L
T----FS
A
P
L
-----
A
T
V
L
S
N
R-FGH
R
L
V
V
M
L
G
---
G
L
L
V
S
T
G
M
V
A
A
-----------------
S
F
---
S
---
Q
--------
E
V
-
S
H
---
M
Y
-
V
A
I
G
I
I
S
G
L
G
Y
C
F
S
-----
F
L
P
----
T
V
T
I
L
S
Q
Y
------F-G----K-
R
R
S
I
--
V
T
AV-ASTG
E
C
F
A
V
F
A
F
A
P
A
I
M
A
------
L
K
E
--------------------------R--------IG-
W
R
Y
S
L
L
F
V
G
L
L
Q
L
N
I
V
I
F
G
A
L
L
R
P
I
F
I
RG-----PAS
P
K
-
I
V
I
QENR
K
E
A
Q
Y
M
LENEKTRTSIDSIDSG
V
E
L
TTSPK---------------NVPTHTN
L
E
LEPKA
D
M
Q
Q
V
L
V
KTSPRPSEKKAPL
L
D
F
-
S
I
L
K
EK
S
F
I
C
Y
A
L
F
G
L
F
A
T
L
--
G
F
FAP
S
----
L
Y
I
I
P
-
L
G
I
S-LGID
Q
D
R
A
A
F
L
L
S
T
M
A
I
A
E
V
F
G
RIGA
G
F
V
LN
R
E
P
---
I
R
----
K
I
Y
I
E
L
I
-
C
V
I
L
L
T
V
S
L
F
--
A
F
T
F
--
A
T
E
F
W
G
L
M
S
C
------------------------
S
I
F
F
G
F
M
V
GTIGGTHI
P
------------------------
L
-L-A-EDDVV
G
I
E
K
MSSAA
G
V
Y
-
I
-
F
I
Q
S
I
AGL-AGPP
L
A
G
L
LV
D
Q
S
K
I
Y
S
R
A
F
Y
S
C
A
A
G
M
A
L
A
A
V
C
L
A
L
V
R
P
C
K
M
G
L
C
QHHH-------------SGE
T
K
V
VSHRG
K
T
L
Q
D
I
P
E
D
F
L
E
M
D
------LAKNE
H
R
V
H
V
Q
MEPV---------------
27
Fugue
90.22
17%
-103
- C2 -
3WDO
-
?
A:
[1-453]
----------------------
D
Y
K
M
T
P
G
E
R
R
A
T
W
-----
G
L
G
T
V
F
S
L
R
M
L
G
M
F
M
V
L
P
V
L
T
T
Y
G
---------
M
-
A
L
---
Q
---
G
A
S
E
A
L
I
G
I
A
I
G
I
Y
G
L
T
Q
A
----
V
F
Q
I
P
-----
F
G
L
L
S
D
R
-
I
G
R
K
P
L
I
V
G
G
---
L
A
V
F
A
A
G
S
V
I
A
-----------------
A
L
---
S
---
D
--------
S
I
-
W
G
---
I
I
-
L
G
R
A
L
Q
G
S
G
A
I
A
A
A
-----
V
M
A
----
L
L
S
D
L
T
R
E
------
Q
-
N
----
R
-
T
K
A
M
--
A
F
I
G
-
V
S
F
G
I
T
F
A
I
A
M
V
L
G
P
I
I
T
------
H
K
L
--------------------------
G
----------------------------
L
H
A
L
F
W
M
I
A
I
L
A
-----
T
T
G
I
A
-
L
T
I
W
V
V
P
N
S
S
T
H
V
L
N
R
E
S
G
M
V
-------------------------------------------
K
G
S
F
S
K
V
L
--
A
E
P
R
L
L
K
L
N
F
G
I
M
C
L
-
H
M
L
L
M
S
T
F
V
--
A
L
P
G
Q
L
A
D
A
--
G
F
P
---------------------
A
A
E
H
W
K
V
Y
L
A
T
M
L
I
A
F
G
S
V
V
P
F
I
I
Y
A
E
V
K
R
K
---
M
K
----
Q
V
F
V
F
C
V
-
G
L
I
V
V
-
A
E
I
V
--
L
W
N
A
--
Q
T
Q
F
W
Q
L
V
V
G
------------------------
V
Q
L
F
F
V
A
F
N
L
M
E
A
L
L
P
S
------------------------
L
-
I
-
S
-
K
E
S
P
A
G
--
Y
K
G
T
A
M
G
V
Y
-
S
-
T
S
Q
F
L
G
V
A
-
I
G
G
S
L
G
G
W
I
D
G
M
F
D
G
Q
G
V
F
L
A
G
A
M
L
A
A
V
W
L
A
V
A
S
T
M
K
E
P
P
Y
V
S
S
L
R
I
E
I
-------------
P
A
D
I
A
A
N
E
A
L
K
V
R
L
L
E
-
T
E
G
V
K
E
V
L
------
I
A
E
E
E
H
S
A
Y
V
K
I
D
S
K
VTN
R
F
E
V
E
Q
A
I
R
QAL
26
Fugue
86.87
17%
-112
- C2 -
4IKW
13
?
A:
[3-494]
-------------------
S
I
D
K
Q
Q
I
A
A
S
V
P
Q
R
G
F
FGHPK
G
L
F
T
L
F
F
T
-
E
F
W
E
R
F
S
Y
Y
G
M
R
A
I
L
V
Y
---
Y
M
Y
Y
E
-
V
S
KGG
L
---
G
L
D
E
H
L
A
L
A
I
M
S
I
Y
G
A
L
V
Y
----
M
S
G
I
I
-----
G
G
W
L
A
D
R
V
F
G
T
S
R
A
V
F
Y
G
---
G
L
L
I
M
A
G
H
I
A
L
-----------------
A
I
---
P
---
G
--------
G
V
-
A
A
---
L
F
-
V
S
M
A
L
I
V
L
G
T
G
L
L
K
-----
P
N
V
----
S
S
I
V
G
D
M
Y
KPGDDR
R
-
D
----
A
-
G
F
S
I
--
F
Y
M
G
-
I
N
L
G
A
F
L
A
P
L
V
V
G
T
A
G
M
K
------
Y
N
------------------------------------
F
H
-
L
G
F
G
L
A
A
V
G
M
F
L
G
L
V
V
F
V
A
T
R
K
K
N
L
G
L
A
G
-----
T
Y
V
P
N
P
L
T
P
A
E
K
K
K
A
A
A
I
M
A
V
G
A
V
V
I
A
V
L
L
A
I
L
I
P
N
G
W
F
T
V
E
T
---------------
F
I
S
L
V
G
I
L
G
I
I
I
P
I
I
Y
F
V
V
M
Y
R
S
P
K
T
T
A
E
E
R
S
R
V
I
A
Y
-
I
P
L
F
V
A
S
A
M
F
W
A
I
Q
E
Q
G
S
T
I
L
A
N
Y
A
D
K
R
----
T
Q
L
D
V
-
A
G
I
H
-
L
S
P
A
W
F
Q
S
L
N
P
L
F
I
I
I
L
A
P
V
F
A
W
M
W
V
K
L
--
G
K
R
Q
---
P
T
----
I
P
Q
K
F
A
L
-
G
L
L
F
A
G
L
S
F
I
--
V
I
L
V
--
P
G
H
L
S
G
G
-----------------------------------
G
L
V
H
P
I
W
L
V
------------------------
L
-
S
-
Y
-
F
I
V
V
L
G
E
L
C
L
S
P
V
G
-------
L
S
A
T
T
K
L
-
A
------
P
A
A
F
S
A
Q
T
M
S
L
W
F
L
S
N
A
A
A
Q
A
I
N
A
Q
L
V
R
F
Y
T
P
-----------------------
E
N
E
T
A
Y
F
G
T
I
G
G
A
A
L
V
L
G
L
I
L
L
A
I
A
------
P
R
I
G
R
L
M
K
G
---------------------
10
HHSearch
83.48
16%
-131
- C2 -
1PW4
-
GLPT_ECOLI
A:
[22-431]
------------------------------
T
Y
R
R
L
-----
R
W
Q
I
F
L
G
I
-
F
F
G
Y
A
A
Y
Y
L
V
R
K
N
F
A
L
A
---
M
P
Y
L
V
--
E
---
Q
---
G
F
S
R
G
D
L
G
F
A
L
S
G
I
S
I
A
Y
G
----
F
S
K
F
I
-----
M
G
S
V
S
D
R
-
S
N
P
R
V
F
L
P
A
G
---
L
I
L
A
A
A
V
M
L
F
M
-----------------
G
F
---
V
---
P
W
A
T
S
----
S
I
-
A
V
---
M
F
-
V
L
L
-
F
L
C
G
W
F
Q
G
M
G
-----
W
P
P
----
C
G
R
T
M
V
H
W
------
W
-
S
Q---
K
-
E
R
G
G
--
I
V
S
V
-
W
N
C
A
H
N
V
G
G
G
I
P
P
L
L
F
L
L
------
G
M
A
W-------------------------
F
--------
N
D
-
W
H
A
A
L
Y
M
P
A
F
C
A
I
L
V
A
L
F
A
F
A
M
M
R
---
D
T
-----
P
Q
S
C
G
-
L
P
P
-
I
E
E
Y
K
-----
N
D
-----------------------------------------------------------------
T
A
K
Q
I
F
M
Q
-
Y
V
L
P
N
K
L
L
W
Y
I
A
I
A
N
V
F
V
Y
L
--
L
R
Y
G
I
L
----
D
W
S
P
T
-
Y
L
K
E
V
K
H
F
A
L
D
K
S
S
W
A
Y
F
L
Y
E
Y
A
G
I
P
G
T
L
L
C
G
W
M
S
D
K
V
F
---
R
G
----
N
R
G
A
T
G
V
F
F
M
T
L
V
T
I
A
T
I
--
V
Y
W
M
NP
A
G
N
P
T
V
D
M
I
C
------------------------
M
I
V
I
G
F
L
I
Y
G
---
P
V
M
L
------------------------
I
-
G
L
H
-
A
L
E
L
A
P
K
K
A
A
G
T
A
A
G
F
T
-
G
-
L
F
G
Y
L
G
G
S
V
A
A
S
A
I
V
G
Y
T
V
D
F
F
G
-
W
D
G
G
F
M
V
M
I
G
G
S
I
L
A
V
I
L
L
I
V
V
M
I
G
E
K
R
R
H
E
Q
L
L
-------------
Q
E
L
V
P
--------------------------------------------------------
24
Fugue
81.20
12%
-129
* C2 *
1PW4
-
GLPT_ECOLI
A:
[5-451]
-------------
F
K
P
A
P
H
K
A
R
L
P
A
A
E
I
D
P
T
Y
R
R
L
-----
R
W
Q
I
F
L
G
I
-
F
F
G
Y
A
A
Y
Y
L
V
R
K
N
F
A
L
A
---
M
P
Y
L
V
-
E
Q
-------
G
F
S
R
G
D
L
G
F
A
L
S
G
I
S
I
A
Y
G
----
F
S
K
F
I
-----
M
G
S
V
S
D
R
-
S
N
P
R
V
F
L
P
A
G
---
L
I
L
A
A
A
V
M
L
F
M
-----------------
G
F
---
V
---
P
--------
W
A
-
T
S
SIA
V
M
-
F
V
L
L
F
L
C
G
W
F
Q
G
M
G
-----
W
P
P
----
C
G
R
T
M
V
H
W
------
W
S
Q
----
K
-
E
R
G
G
--
I
V
S
V
-
W
N
C
A
H
N
V
G
G
G
I
P
P
L
L
F
L
L
------
G
M
A
--------------------------
W
--------
F
N
D
W
H
A
A
L
Y
M
P
A
F
C
A
I
L
V
A
L
F
A
F
A
M
-----------------------------------------------------
M
R
---------------
D
T
P
Q
S
C
G
L
P
------------
P
I
E
E
Y
K
N
D
T
A
K
Q
I
F
M
Q
-
Y
V
L
P
N
K
L
L
W
Y
I
A
I
A
N
V
F
V
Y
L
--
L
R
Y
G
I
L
----
D
W
S
P
T
Y
L
K
E
V
-
K
H
F
A
L
D
K
S
S
W
A
Y
F
L
Y
E
Y
A
G
I
P
G
T
L
L
C
G
W
M
S
D
K
V
F
RGN
R
G
----
A
T
G
V
F
F
M
-
T
L
V
T
I
A
T
I
V
Y
--
W
M
N
P
--
A
G
N
P
T
V
D
M
I
C
------------------------
M
I
V
I
G
F
L
I
Y
G
P
V
M
L
I
G
L
------------------------
H
-
A
-
L
-
E
--
L
A
P
K
K
A
A
G
T
A
A
G
F
T
-
G
-
L
F
G
Y
L
G
G
S
-
V
A
A
S
A
I
V
G
Y
T
V
D
F
F
G
W
D
G
G
F
M
V
M
I
G
G
S
I
L
A
V
I
L
L
I
V
V
M
I
G
E
K
R
R
H
E
Q
L
L
-------------
Q
E
L
V
P
--------------------------------------------------------
30
Fugue
72.91
13%
-114
- C2 -
2GFP
-
EMRD_ECOLI
A:
[9-383]
-------------------------------------------
L
L
L
M
L
-
V
L
L
V
A
V
G
Q
M
A
Q
T
I
Y
I
P
A
---
I
A
D
M
A
-
R
D
---
L
---
N
V
R
E
G
A
V
Q
S
V
M
G
A
Y
L
L
T
Y
G
----
V
S
Q
L
F
-----
Y
G
P
I
S
D
R
-
V
G
R
R
P
V
I
L
V
G
---
M
S
I
F
M
L
A
T
L
V
A
-----------------
V
T
---
T
---
S
--------
S
L
-
T
V
----
L
-
I
A
A
S
A
M
Q
G
M
G
T
G
V
G
-----
G
V
M
----
A
R
T
L
P
R
D
L
------
Y
-
E
----
R
-
T
Q
L
R
--
H
A
N
S
-
L
L
N
M
G
I
L
V
S
P
L
L
A
P
L
I
G
G
L-----
L
D
T
--------------------------
M
--------
W
N
-
W
R
A
C
Y
L
F
L
L
V
L
C
A
G
V
T
F
S
M
A
R
W
M
P
-----------------------------------------------------------------------------------------
E
T
R
P
V
D
A
P
R
T
R
L
L
T
S
Y
K
T
L
F
G
N
S
G
F
N
C
Y
L
L
M
L
I
G
G
L
A
--
G
I
A
A
F
E
----
A
C
S
G
V
-
L
M
G
---------
A
V
L
G
L
S
S
M
T
V
S
I
L
F
I
L
P
I
P
A
A
F
F
G
A
W
F
---
A
G
----
R
P
N
K
R
F
S
-
T
L
M
W
Q
S
V
I
C
C
--
L
L
A
G
----------------------------------------------------
L
------------------------
L
-
M
-
W
-
I
P
D
W
F
G
V
M
N
V
W
T
L
L
V
P
A
-
A
-
L
F
F
F
G
A
G
M
-
L
F
P
L
A
T
S
G
A
M
E
P
F
P
F
L
A
G
T
A
G
A
L
V
G
G
L
Q
N
I
G
S
G
V
L
-----------------------------
A
S
L
S
A
M
L
P
Q
T
G
Q
G
S
L
G
L
L
M
T
L
M
G
------
L
L
I
V
L
C
W
L
P
L
--------------------
28
Fugue
72.64
14%
-106
- C2 -
4GC0
5
XYLE_ECOLI
A:
[5-479]
---------------
Y
N
S
S
Y
I
F
S
I
T
L
V
A
T
L
G
G
L
L
F
-----
G
Y
D
T
A
V
I
S
-
G
T
V
E
S
L
N
T
V
F
V
A
P
Q
N
L
-----------
S
---
E
---
S
A
A
N
S
L
L
G
F
C
V
A
S
A
L
I
G
C
I
----
I
G
G
A
L
-----
G
G
Y
C
S
N
R
-
F
G
R
R
D
S
L
K
I
A
---
A
V
L
F
F
I
S
G
V
G
S
A
WPELGFTSINPDNTVP
V
Y
---
L
---
A
--------
G
Y
-
V
P
---
E
F
-
V
I
Y
R
I
I
G
G
I
G
V
G
L
A
-----
S
M
L
----
S
P
M
Y
I
A
E
L
------
A
P
A
----
H
-
I
R
G
K
--
L
V
S
F
-
N
Q
F
A
I
I
F
G
Q
L
L
V
Y
C
V
N
Y
F
------
I
A
R
--------------------------
S
GD
A
S
W
L
N
T
D
G
-
W
R
Y
M
F
A
S
E
---
C
I
P
A
L
L
F
L
M
L
L
Y
T
V
---------
P
E
S
P
R
-
W
L
M
S
R
G
K
--------
Q
E
Q
A
E
G
I
L
R
K
I
M
G
--------------------------
N
T
L
A
T
Q
A
V
Q
E
I
K
H
S
L
D
H
G
R
K
T
G
G
R
L
L
M
F
G
V
G
V
I
V
I
-
G
V
M
L
S
I
F
Q
Q
F
---
V
G
I
N
V
V
L
--
Y
Y
A
P
E
V
----
F
K
T
L
G
-
A
S
T
D
-
I
A
L
L
Q
T
I
I
V
G
V
I
N
L
T
F
T
V
L
A
I
M
T
V
D
K
F
---
G
R
K
P
---
L
Q
----
I
I
G
A
L
G
M
-
A
I
G
M
F
S
L
G
T
A
--
F
Y
T
Q
--
A
P
G
I
V
A
L
L
S
M
------------------------
L
F
Y
V
A
A
F
A
M
S
W
G
P
V
C
W
V
------------------------
L
-
L
-
S
-
E
--
I
F
P
N
A
I
R
G
K
A
L
A
I
A
-
V
-
A
A
Q
W
L
A
N
Y
-
F
V
S
W
T
F
P
M
M
D
K
N
S
W
L
V
A
H
F
H
N
G
F
S
Y
W
I
Y
G
C
M
G
V
L
A
A
L
F
M
W
K
F
-------------------------
V
P
E
T
K
G
K
T
L
E
E
L
E
A
L
W
E
---------------------------------------
32
Fugue
65.33
14%
-101
- C1 -
1B25
2
?
A:
[1-619]
MYGWWG
R
I
L
R
V
N
L
T
T
G
E
V
K
V
Q
E
Y
P
E
E
V
A
K
K
F
I
G
G
R
-----
G
L
A
A
W
I
L
W
-
N
E
A
R
-
G
V
E
P
L
S
P
E
N
K
L
I
---
F
A
A
G
P
-
F
N
---
G
---
L
P
-------
T
P
S
G
G
K
L
V
V
A
----
A
K
S
P
L
TG
G
Y
G
D
G
N
L
G
T
M
-
A
S
V
H
L
R
R
A
G
Y
---
D
A
L
V
V
E
G
K
A
K
K
-----------------
P
V
---
Y
---
I
--------
Y
I
-
E
D
---
D
N
-
V
S
I
L
S
A
E
G
L
-
W
G
K
T
-----
T
F
E
----
T
E
R
E
L
K
E
I
------
H
-
G
------
K
N
V
G
--
V
L
T
I
-
G
P
A
G
E
N
L
V
K
Y
A
---
V
V
I
S
------
Q
E
G
--------------------------
R
--------
A
A
-
G
R
P
G
--------
M
G
A
V
M
G
S
K
K
L
K
A
V
V
I
R
G
TKEIP
V
A
D
K
E
-
E
L
K
K
L
S
Q
E
A
Y
N
E
I
L
N
S
P
G
-
Y
P
F
W
K
R
Q
G
T
M
A
A
V
E
W
C
N
T
N
YALPTRNFSDGYFE
F
A
R
S
I
D
G
Y
T
M
E
G
M
-
K
V
Q
Q
R
G
C
P
Y
C
N
M
P
C
G
N
V
V
L
D
A
E
G
-
Q
E
S
E
L
-
D
Y
E
N
V
A
L
L
G
S
N
L
G
I
--
G
K
L
N
E
V
----
S
V
L
N
R
-
I
A
D
E
-
M
G
M
D
T
I
S
L
G
V
S
I
A
H
V
M
E
A
V
E
R
G
I
L
K
-------
E
G
---
P
T
F
GD
F
K
G
A
K
Q
L
A
-
L
D
I
A
Y
R
K
G
E
L
--
G
N
L
A
--
A
E
G
V
K
A
M
A
E
K
L
GTHDFAMHVKG
L
E
V
S
GYNCYIY
P
A
M
A
L
A
Y
G
T
S
A
I
G
A
H
H
K
E
AWV
I
A
W
E
I
GTAPIEYKISYD
P
I
K
A
Q
-
K
-
V
-
V
E
L
Q
R
L
R
G
G
L
F
E
M
L
T
A
C
-
R
-
L
P
W
V
E
V
G
L
-
S
L
D
Y
Y
P
K
L
L
K
A
I
T
G
V
T
Y
T
W
D
D
L
Y
K
A
A
D
R
V
Y
S
L
I
R
A
Y
W
V
R
E
F
N
G
K
W
D
R
K
M
DYPP
K
R
W
F
T
EGLK
S
G
P
H
K
G
E
H
L
D
E
K
K
Y
D
E
L
L
S
E
Y
Y
R
I
R
GWDERG
I
P
K
K
E
T
L
K
E
L
D
L
D
F
V
I
P
E
L
E
K
V
TNLE----
25
Fugue
64.74
11%
-125
- C2 -
1PV6
-
LACY_ECOLI
A:
[1-417]
------------
M
Y
Y
L
K
---------------
N
T
N
-----
F
W
M
F
G
L
F
F
-
F
F
Y
F
F
I
M
G
A
Y
F
P
F
F
P
I
W
---
L
H
D
I
N
-
H
I
---------
S
K
S
D
T
G
I
I
F
A
A
I
S
L
F
S
L
----
L
F
Q
P
L
-----
F
G
L
L
S
D
K
-
L
G
L
R
K
Y
L
L
W
I
---
I
T
G
M
L
V
M
F
A
P
F
-----------------
F
I
F
I
F
G
---
P
--------
L
L
-
Q
Y
---
N
I
-
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
-----
F
N
A
----
G
A
P
A
V
E
A
F
------
I
-
E
----
K
-
V
S
R
R
SN
F
E
F
G
-
R
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
------
I
M
F
--------------------------
T
--------
I
N
-
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
T
D
---------------------------------------------------------------------------
A
P
S
S
A
T
V
A
N
A
V
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
-
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
--
D
Q
Q
F
A
-----
N
F
F
T
S
-
F
F
A
T
-
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
---
G
K
----
N
A
L
L
L
A
G
-
T
I
M
S
V
R
I
I
G
S
--
S
F
----
A
T
S
A
L
E
V
V
I
L
------------------------
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
------------------------
Y
-
I
-
T
-
S
Q
--
F
E
V
R
F
S
A
T
I
Y
L
V
C
-
F
C
F
F
K
Q
L
A
M
I
-
F
M
S
V
L
A
G
N
M
Y
E
S
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
----------------------------------------------
L
S
G
P
------
G
P
L
S
L
L
R
R
Q
V
N
E
V
A
----------------
29
Fugue
63.58
10%
-80
- C2 -
2XUT
-
?
A:
[13-500]
------------------
Q
I
P
Y
I
I
A
S
E
A
C
E
R
F
S
F
Y
-----
G
M
R
N
I
L
T
P
-
F
L
M
T
A
L
L
L
S
-----------------
I
P
---
E
---
E
L
R
G
A
V
A
K
D
V
F
H
S
F
V
I
G
V
Y
----
F
F
P
L
L
-----
G
G
W
I
A
D
R
F
F
G
K
Y
N
T
I
L
W
L
---
S
L
I
Y
C
V
G
H
A
F
L
-----------------
A
I
---
F
---
E
--------
H
S
-
V
Q
---
G
F
-
Y
T
G
L
F
L
I
A
L
G
S
G
G
I
-----
K
P
L
----
V
S
S
F
M
G
D
Q
------
F
-
D
QSNK
S
-
L
A
Q
K
--
A
F
D
M
-
F
Y
F
T
I
N
F
G
S
F
F
A
S
L
S
M
P
L
------
L
L
K
--------------------------
N
--------
F
G
-
A
A
V
A
F
G
I
P
G
V
L
M
F
V
A
T
V
F
F
W
L
G
R
K
R
Y
I
H
M
-----
P
V
E
G
-----
K
G
N
I
G
L
V
L
A
L
I
G
G
V
S
A
A
Y
A
L
V
N
I
P
T
L
G
I
V
A
G
L
C
C
---------------
A
M
V
L
V
M
G
F
V
G
A
G
A
S
L
Q
L
E
R
A
R
K
S
H
P
D
A
A
V
D
------------
G
V
R
S
V
L
R
I
L
V
L
F
A
L
V
T
--
P
F
W
S
-------------------
L
F
D
Q
K
A
S
T
W
I
L
Q
A
N
D
M
V
K
P
Q
W
F
E
P
A
M
M
Q
A
L
N
P
---
L
L
----
V
M
L
L
I
P
F
-
N
N
F
V
T
A
L
R
K
M
G
A
G
I
A
I
--
T
G
L
S
W
I
V
V
G
T
------------------------
I
Q
L
M
M
D
G
G
S
A
L
S
I
F
W
Q
I
------------------------
L
-
P
-
Y
-
A
L
L
T
F
G
E
V
L
V
S
A
T
G
-------------
L
-
E
F
A
Y
S
Q
A
P
K
A
M
K
G
T
I
M
S
F
W
T
L
S
V
T
V
G
N
L
W
V
L
L
A
N
V
S
V
K
S
--------
P
T
-------------
V
T
E
Q
I
V
Q
T
G
M
S
V
T
A
F
Q
M
F
F
F
A
G
F
A
I
------
L
A
A
I
V
F
A
-----------------------
14
HHSearch
60.05
11%
-111
- C2 -
2CFQ
-
LACY_ECOLI
A:
[25-393]
-------------------------------------------------------------
A
Y
F
P
F
---
F
P
I
W
L
-
H
D
I--
N
---
H
I
S
K
S
D
T
G
I
I
F
A
A
I
S
L
F
S
L
----
L
F
Q
P
L
-----
F
G
L
L
S
D
K
-
L
G
L
R
K
Y
L
L
W
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
-----------------
I
F
---
G
---
P
--------
L
L
Q
Y
N
---
I
L
-
V
G
S
-
I
V
G
G
I
Y
L
G
F
C
-----
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
------
S
------
R
-
R
S
N
F
--
E
F
G
R
-
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
I
------
M
F
T
-----------------------------------
I
N
-
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
----
K
T
D
-----
A
P
S
S
---
A
T
V
A
-
N
A
V
------
G
A
-------------------
N
---------------
H
S
----------------------
A
F
---
S
L
K
L
--
A
L
-
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
C
--
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
-
F
F
A
T
-
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
---
G
K
----
N
A
L
L
L
---
A
G
T
I
M
S
V
R
I
I
--
G
S
S
F
--
A
T
S
A
L
E
V
V
I
----------------------------
L
K
T
L
H
M
F
E
V
P
F
L
L
V
------------------------
G
C
F
-
K
Y
I
T
S
Q
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
-
F
F
K
Q
L
A
M
I
-
F
M
S
V
L
A
G
N
M
Y
E
S
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
S
L
L
R
R
-------------
Q
V
N
E
V
A
-------------------------------------------------------
5
PsiBlast_PDB
55.13
22%
-147
- C2 -
2CFP
-
LACY_ECOLI
A:
[222-394]
-----------------------------------------------
L
-
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
-
T
S
---
F
FAT
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
--------
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
S
A
L
E
V
V
I
L
K
T
-
L
H
---
M
F
-
E
V
P
F
L
L
V
G
---
C
F
K
-----
Y
---------
I
T
S
Q
F
------
E
-
V
----
R
-
F
S
A
T
--
I
Y
L
V
------
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
--------------------------
S
--------
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
-----
S
L
L
R
R
-
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
54.10
22%
-147
- C2 -
1PV6
-
LACY_ECOLI
A:
[222-394]
-----------------------------------------------
L
-
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
-
T
S
---
F
FAT
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
--------
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
S
A
L
E
V
V
I
L
K
T
-
L
H
---
M
F
-
E
V
P
F
L
L
V
G
---
C
F
K
-----
Y
---------
I
T
S
Q
F
------
E
-
V
----
R
-
F
S
A
T
--
I
Y
L
V
------
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
--------------------------
S
--------
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
-----
S
L
L
R
R
-
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
53.59
22%
-144
- C2 -
2V8N
-
LACY_ECOLI
A:
[222-394]
-----------------------------------------------
L
-
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
-
T
S
---
F
FAT
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
--------
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
S
A
L
E
V
V
I
L
K
T
-
L
H
---
M
F
-
E
V
P
F
L
L
V
G
---
C
F
K
-----
Y
---------
I
T
S
Q
F
------
E
-
V
----
R
-
F
S
A
T
--
I
Y
L
V
------
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
--------------------------
S
--------
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
-----
S
L
L
R
R
-
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
53.44
22%
-152
- C2 -
1PV7
1
LACY_ECOLI
A:
[222-394]
-----------------------------------------------
L
-
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
-
T
S
---
F
FAT
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
--------
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
S
A
L
E
V
V
I
L
K
T
-
L
H
---
M
F
-
E
V
P
F
L
L
V
G
---
C
F
K
-----
Y
---------
I
T
S
Q
F
------
E
-
V
----
R
-
F
S
A
T
--
I
Y
L
V
------
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
--------------------------
S
--------
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
-----
S
L
L
R
R
-
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
53.12
22%
-149
- C2 -
2CFQ
-
LACY_ECOLI
A:
[222-394]
-----------------------------------------------
L
-
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
-
T
S
---
F
FAT
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
--------
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
S
A
L
E
V
V
I
L
K
T
-
L
H
---
M
F
-
E
V
P
F
L
L
V
G
---
C
F
K
-----
Y
---------
I
T
S
Q
F
------
E
-
V
----
R
-
F
S
A
T
--
I
Y
L
V
------
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
--------------------------
S
--------
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
-----
S
L
L
R
R
-
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
48.94
14%
-121
- C2 -
2GFP
-
EMRD_ECOLI
A:
[24-172]
-----------------------------------------------------------
Q
T
I
Y
I
P
A
---
I
A
D
M
A
-
R
D
---
L
---
N
V
R
E
G
A
V
Q
S
V
M
G
A
Y
L
L
T
Y
G
----
V
S
Q
L
F
-----
Y
G
P
I
S
D
R
-
V
G
R
R
P
V
I
L
V
G
---
M
S
I
F
M
L
A
T
L
V
A
-----------------
V
T
---
T
---
S
--------
S
L
-
T
V
---
L
I
-
A
A
S
-
A
M
Q
G
M
G
T
G
V
G
-----
G
V
M
----
A
R
T
L
P
R
D
L
------
Y
-
E
R
---
T
-
Q
L
R
H
--
A
N
S
L
-
L
N
M
G
I
L
V
S
P
L
L
A
P
L
I
G
G
L
------
L
D
T
--------------------------
M
--------
W
N
-
W
R
A
C
Y
L
F
L
L
V
L
C
A
G
V
T
F
S
M
A
R
W
M
P
E
T
R
P
V
-----
D
A
P
R
T
-
R
L
L
T
S
Y
K
T
L
F
G
N
S
G
F
N
C
Y
L
L
M
L
I
G
G
L
A
G
I
A
A
F
E
A
C
S
G
---------------
V
L
M
G
A
V
L
G
L
S
S
M
T
V
S
I
L
F
I
L
P
I
P
A
A
F
F
G
A
W
F
A
G
R
P
N
K
-
R
F
S
T
L
M
W
Q
S
V
I
C
C
L
L
A
G
L
L
M
--
W
I
P
D
W
F
----
G
V
M
N
V
-
W
T
L
L
-
V
P
A
A
L
F
F
F
G
A
G
M
L
F
P
L
A
T
S
G
A
M
E
P
F
P
F
L
A
G
T
A
G
A
---
L
V
----
G
G
L
Q
N
I
G
-
S
G
V
L
A
S
L
S
A
M
--
L
P
Q
T
--
G
Q
G
S
L
G
L
L
M
T
------------------------
L
M
G
L
L
I
V
L
C
W
L
P
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
48.68
11%
-124
- C2 -
3O7Q
1
FUCP_ECOLI
A:
[37-219]
------------------------------------------------------
L
W
A
V
A
N
N
L
N
D
I
L
---
L
P
Q
F
Q
-
Q
A
---
F
---
T
L
T
N
F
Q
A
G
L
I
Q
S
A
F
Y
F
G
Y
F
----
I
I
P
I
P
-----
A
G
I
L
M
K
K
-
L
S
Y
K
A
G
I
I
T
G
---
L
F
L
Y
A
L
G
A
A
L
F
-----------------
W
P
---
A
A
E
I
M
--------
N
Y
-
T
L
---
F
L
-
V
G
L
-
F
I
I
A
A
G
L
G
C
L
-----
E
T
A
----
A
N
P
F
V
T
V
L
------
G
-
P
----
E
S
S
G
H
F
--
R
L
N
L
-
A
Q
T
F
N
S
F
G
A
I
I
A
V
V
F
G
Q
S
------
L
I
L
SNVPHQS
Q
D
V
L
D
K
MS
P
E
Q
L
S
A
Y
K
H
S
L
V
--------
L
S
-
V
Q
T
P
Y
M
I
I
V
A
I
V
L
L
V
A
L
L
I
M
L
T
K
F
P
A
L
Q
S
-----
D
N
H
S
D
-
A
K
Q
G
S
F
S
A
S
L
S
R
L
A
R
I
R
H
W
R
W
A
V
L
A
Q
F
C
Y
V
G
A
Q
T
A
C
W
---------------
S
Y
L
I
R
Y
A
V
E
E
I
P
G
M
T
A
G
F
A
A
N
Y
L
T
G
T
M
V
C
F
F
I
G
R
F
T
G
-
T
W
L
I
S
R
F
A
P
H
K
V
L
A
A
Y
A
L
I
A
--
M
A
L
C
L
I
----
S
A
F
A
G
-
G
H
V
G
-
L
I
A
L
T
L
C
S
A
F
M
S
I
Q
Y
P
T
I
F
S
L
G
I
K
N
L
G
Q
D
T
K
Y
G
S
---
S
F
----
I
V
M
T
I
I
G
-
G
G
I
V
T
P
V
M
G
F
--
V
S
D
A
--
A
G
N
I
P
T
A
E
L
I
------------------------
P
A
L
C
F
A
V
I
F
I
F
A
R
F
R
S
Q
------------------------
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
47.67
21%
-113
- C2 -
2Y5Y
1
LACY_ECOLI
A:
[222-385]
-----------------------------------------------
L
-
W
F
L
S
L
Y
V
I
G
V
S
S
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
-
T
S
---
F
FAT
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
--------
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
S
A
L
E
V
V
I
L
K
T
-
L
H
---
M
F
E
V
P
F
L
L
V
G
S
F
K
Y
I
T
S
QFEVR
F
S
A
----
T
I
Y
L
V
A
F
A
------
F
-
F
----
K
-
Q
L
A
M
--
I
F
M
S
-
V
L
A
G
N
M
Y
E
S
I
G
F
Q
G
A
Y
L
V
------
L
G
L
--------------------------
V
--------
A
L
-
G
F
T
L
I
S
V
F
T
L
S
G
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
45.19
15%
-113
- C2 -
2CFQ
-
LACY_ECOLI
A:
[257-390]
--------------------------------------------------------------------------------------
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
----
S
I
M
F
F
-----
A
P
L
I
I
N
R
-
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
-----------------
S
F
---
A
---
T
--------
S
A
-
L
E
---
V
V
-
I
L
K
-
T
L
H
M
F
E
V
P
F
L
-----
L
V
G
----
C
F
K
Y
I
T
S
Q
------
F
-
E
V---
R
-
F
S
A
T
--
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
------
M
Y
E
--------------------------
S
--------
I
G
-
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
-----
S
L
L
R
R
-
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
44.70
14%
-131
- C2 -
3WDO
-
?
A:
[29-175]
--------------------------------------------------------------
V
L
P
V
---
L
T
T
Y
G
M
A
L
---
Q
---
G
A
S
E
A
L
I
G
I
A
I
G
I
Y
G
L
T
Q
A
----
V
F
Q
I
P
-----
F
G
L
L
S
D
R
-
I
G
R
K
P
L
I
V
G
G
---
L
A
V
F
A
A
G
S
V
I
A
-----------------
A
L
---
S
---
D
--------
S
I
-
W
G
---
I
I
-
L
G
R
-
A
L
Q
G
S
G
A
--
I
-----
A
A
A
----
V
M
A
L
L
S
D
L
------
T
-
R
E---
Q
-
N
R
T
K
--
A
M
A
F
-
I
G
V
S
F
G
I
T
F
A
I
A
M
V
L
G
P
I
------
I
T
H
--------------------------
K
--------
L
G
-
L
H
A
L
F
W
M
I
A
I
L
A
T
T
G
I
A
L
T
I
W
V
V
P
N
S
S
T
H
-----
V
L
N
R
E
-
S
G
M
V
K
G
S
F
S
K
V
L
A
E
P
R
L
L
K
L
N
F
G
I
M
C
L
H
M
L
L
M
S
T
F
V
A
---------------
L
P
G
Q
L
A
D
A
G
F
P
A
A
E
H
W
K
V
Y
L
A
T
M
L
I
A
F
G
S
V
V
P
F
I
I
Y
A
-
E
V
K
R
K
M
K
Q
V
F
V
F
C
V
G
L
I
V
V
A
--
E
I
V
L
W
N
----
A
Q
T
Q
F
-
W
Q
L
V
-
V
G
V
Q
L
F
F
V
A
F
N
L
M
E
A
L
L
P
S
L
I
S
K
E
S
P
A
G
Y
K
G
T
A
M
---
G
V
----
Y
S
T
S
Q
F
L
-
G
V
A
I
G
G
S
L
G
G
--
W
I
D
G
--
M
F
D
G
Q
G
V
F
L
A
------------------------
G
A
M
L
A
A
V
W
L
A
V
A
S
T
M
K
E
------------------------
P
-
P
-
Y
-
V
S
S
L
R
I
E
I
P
A
D
I
A
A
N
E
A
-
L
-
K
V
R
L
L
E
T
E
-
G
V
K
E
V
L
I
A
E
E
E
H
S
A
Y
V
K
I
D
S
K
V
T
N
R
F
E
V
E
Q
A
I
R
Q
A
L
---------------------------------------------------------------------------------------