@TOME V2.2
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
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Sequence Color type :
Secondary Structure
Hydrophobicity
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TCoffee Identity Score
Uniprot annotation
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Show alignment :
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Column output:
Score:
Atome Rank Value
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Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
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3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
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Structural Clustering:
Cluster Num
3D-Jury Struct. Score
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Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
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Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
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Templates Information:
Uniprot entry
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Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S35F5_HUMAN: (2015-12-10 )
MVPPRRHRGAGRPGVLSSSPPFRLRSAKFSGIALEDLRRALKTRLQMVCVFVMNRMNSQNSGFTQRRRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGLRGKHAAFFADAEGYFAACTTDTTMNSSLSEPLYVPVKFHDLPSEKPESTNIDTEKTPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPVKEQESILKTVGKLTATQVAKISFFFCFVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVLVNLAGSEKPAGRDTVGSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLMCIIINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGIRRIFAFICRKHRIQRVPEDSEQCESLISMHSVSQEDGAS
Atome Classification :
(14 SA)
.........10........20......--..30........40........50........60........70........80........90.--.......100.......110.......120.......130.......-140.......150.......160.....-..170.......180.......190..-.....200.......210.......220....----------...230.......240.......250---........260.......270........280......---.290.......300.......------310.......320.......330.......340.......350...-----....360.......370.......380.......390.......400.......410.......420......-.430.......440.......450.......460.......470.......---480.......490.......500.......510.......520.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVPPRRHRGAGRPGVLSSSPPFRLRSA--KFSGIALEDLRRALKTRLQMVCVFVMNRMNSQNSGFTQRRRMALGIVILLLVDVIWVASSELTSY--VFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGLRGKHAAF-FADAEGYFAACTTDTTMNSSLSEPLYVP-VKFHDLPSEKPESTNIDTEKTPKKSRV-RFSNIMEIRQLPSSHALEAKLSRMSYPVKEQE----------SILKTVGKLTATQVAKISFFFCFVW----FLANLSYQEALSDTQVAIVN-ILSSTSGLFTLILAAVF---PSNSGDRFTLSKLLAVILSIG------GVVLVNLAGSEKPAGRDTVGSIWSLAGAMLYAVYIVMIKRKVDRED-----KLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLMCIIINGLIGTVLSEFLWLWGCFLTSSLIGT-LALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDP---VMVGIRRIFAFICRKHRIQRVPEDSEQCESLISMHSVSQEDGAS
17
Fugue
80.65
22%
-73
- C3 -
4HNE
1
P4K2A_HUMAN
A:
[2-384]
---------------
P
L
G
S
P
E
F
A
A
Q
A
Q
--
A
L
A
A
Q
A
A
A
A
A
H
A
A
Q
A
H
R
E
R
-------
N
E
F
P
E
D
P
E
F
E
A
V
V
R
Q
A
E
L
A
I
E
R
C
I
F
P
E
R
I
Y
Q
G
S
S
G
--
S
Y
--
F
V
K
D
P
Q
G
R
I
I
A
V
F
K
P
K
N
E
E
P
Y
G
H
L
N
P
K
-
W
T
K
W
L
Q
K
F
G
R
D
C
L
V
L
N
Q
G
Y
-
L
S
E
A
----
G
A
S
L
V
D
Q
K
L
E
L
N
I
-----
V
P
R
T
K
V
V
Y
L
A
S
E
T
F
N
Y
S
A
I
D
R
V
K
S
R
G
K
----
R
L
A
L
R
F
N
R
I
G
L
P
P
--------------------------------------------
K
V
G
S
F
Q
L
F
V
----------------------------------------------
E
G
Y
K
D
A
D
Y
W
L
R
R
F
E
A
-----------------------
E
P
L
P
E
N
T
N
R
Q
L
L
L
Q
F
E
R
L
V
V
L
D
Y
I
I
---
R
N
T
D
R
G
N
DN
W
L
I
K
Y
D
C
P
P
V
I
K
V
A
A
I
D
N
G
L
----
A
F
P
L
K
H
P
D
S
W
R
A
Y
P
F
----------------------
Y
W
A
W
------------
L
P
Q
A
K
V
P
F
S
Q
E
I
K
D
L
I
L
P
K
I
S
D
---------
P
N
F
V
K
D
L
E
E
D
L
Y
E
L
F
K
K
-
D
P
GFD
R
G
Q
F
H
K
Q
I
A
V
M
R
G
Q
I
L
N
L
T
Q
A
L
K
D
N
K
S
P
L
H
L
V
Q
M
P
P
V
I
V
E
T
---
15
Fugue
53.41
15%
-40
- C3 -
1IU4
-
TGAS_STRMB
A:
[1-331]
--------
D
S
D
D
R
V
T
P
P
A
E
P
L
D
R
M
P
D
P
Y
R
P
S
Y
G
R
A
E
T
V
V
N
N
Y
I
R
K
W
Q
Q
V
---
Y
S
H
R
D
G
R
K
Q
Q
M
T
E
E
Q
R
E
W
L
S
Y
G
C
V
-----
G
V
T
W
V
N
S
G
Q
Y
P
T
N
RL
A
F
A
S
F
D
E
D
R
F
K
N
E
L
K
N
G
------------
R
P
R
S
G
E
T
R
A
E
F
E
G
R
V
A
K
E
S
F
D
E
E
K
G
F
Q
R
A
R
E
V
A
S
V
M
N
R
A
L
-
E
N
A
H
D
E
-
S
A
Y
L
D
N
L
K
K
E
L
A
N
G
N
D
A
L
R
N
E
D
A
R
S
P
F
--
Y
S
A
L
R
N
T
P
S
F
K
E
R
N
G
G
N
H
D
P
S
R
M
K
A
V
I
Y
S
K
H
F
W
S
GQDRSSS
A
D
K
R
K
Y
G
D
P
D
A
F
R
P
A
P
G
T
G
L
V
D
M
S
R
DRNI
P
R
S
P
T
S
P
G
E
G
F
V
N
F
D
Y
G
W
F
G
-
A
Q
T
E
A
D
A
D
K
T
V
W
T
H
G
N
H
YHA
P
N
G
S
L
G
A
M
H
V
Y
E
S
K
F
R
N
W
S
E
G
YSDFD
R
G
A
Y
V
I
T
F
I
P
K
S
W
N
T
A
P
D
K
V
K
Q
G
W
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
38.00
19%
-124
- C- -
3B5D
1
EMRE_ECOLI
A:
[29-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
W
P
S
V
G
T
I
I
C
Y
----
C
A
S
F
W
L
L
A
Q
T
L
A
Y
I
P
T
G
I
A
Y
A
I
W
S
G
V
G
I
V
L
I
S
L
L
S
W
G
F
---
F
---
G
Q
R
L
D
L
P
A
I
I
G
M
M
L
I
C
A
------
G
V
L
I
I
N
L
L
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
33.61
13%
-199
- C- -
3B5D
1
EMRE_ECOLI
A:
[31-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
P
S
V
G
T
I
I
C
Y
C
A
S
F
W
L
L
A
Q
T
L
A
Y
I
P
T
G
I
A
Y
A
I
W
S
G
V
G
I
V
L
I
S
L
L
S
W
G
F
F
G
Q
R
L
D
L
P
A
I
I
G
M
M
L
I
C
A
G
V
L
I
I
N
L
L
S
------------------------------------------------------
11
Fugue
33.41
16%
194
- C3 -
1WT6
-
DMPK_HUMAN
A:
[6-70]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
V
T
L
R
E
L
Q
E
A
L
E
E
E
V
L
T
R
Q
S
L
S
R
E
M
E
A
I
-
R
T
D
N
Q
N
F
A
S
Q
L
R
E
A
E
A
R
N
R
D
L
E
A
H
V
R
Q
L
Q
E
R
M
----------
E
L
L
Q
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
33.02
19%
234
- C3 -
3A2A
-
HVCN1_HUMAN
A:
[11-51]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
L
L
R
L
K
Q
M
N
V
Q
L
A
A
K
I
Q
H
L
E
F
S
C
S
E
K
E
----------
Q
E
I
E
R
L
N
K
L
L
R
Q
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
31.47
16%
317
- C3 -
4PN8
-
?
A:
[2-31]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
I
E
Q
I
L
Q
K
I
E
K
I
L
Q
K
I
E
----------
W
I
L
Q
K
I
E
Q
I
L
Q
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
31.11
30%
570
- C2 -
2KOG
-
VAMP2_RAT
A:
[8-27]
-
V
P
P
A
A
P
A
G
E
G
G
P
P
A
P
P
P
N
L
T
S
N
R
R
L
Q
--
Q
T
Q
A
Q
V
D
E
V
V
D
I
M
R
V
N
V
D
K
V
L
E
R
D
Q
K
L
S
E
L
D
D
R
A
D
A
L
Q
A
G
A
S
Q
F
E
T
S
A
A
K
L
K
R
K
Y
W
W
K
N
L
K
M
M
I
I
--
L
G
V
I
C
A
I
I
L
I
I
I
I
V
Y
F
S
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
27.30
16%
254
- C3 -
4AXG
-
CUP_DROME
C:
[23-81]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
S
S
K
P
V
K
-
S
Y
T
R
S
R
L
M
D
I
R
N
G
M
I
E
L
E
G
R
L
R
R
M
N
I
W
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
25.65
7%
178
- C3 -
4WXA
-
GON7_YEAST
D:
[2-112]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
P
V
A
Q
Y
S
A
P
D
G
V
E
K
S
F
A
P
L
T
Y
L
G
Q
L
R
T
Q
L
T
G
L
Q
D
D
I
N
E
F
L
T
G
R
M
E
L
A
K
N
K
K
K
A
G
A
----------
D
E
K
R
I
Q
E
E
I
N
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
25.15
23%
162
* C3 *
1E79
-
ATP5E_BOVIN
I:
[1-47]
---------------
V
A
Y
W
R
Q
A
G
L
S
Y
I
--
R
Y
S
Q
I
C
A
K
A
V
R
D
A
L
K
T
E
F
K
A
------
N
A
M
K
T
S
G
S
T
I
K
I
V
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
24.85
29%
425
- C3 -
2DOH
-
C:
[4-28]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
D
A
E
L
Q
R
L
K
N
E
R
H
E
E
A
E
L
E
R
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
24.75
18%
223
- C3 -
3WU2
-
PSBL_THEVL
L:
[4-31]
--------------------------------------------------------
N
P
N
R
Q
P
V
E
L
N
R
-
T
S
L
Y
L
G
L
L
L
I
L
V
L
A
L
L
F
S
S
Y
F
F
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
21.71
50%
3268
- C1 -
2KDT
-
NEC1_MOUSE
A:
[733-738]
---
P
Y
K
H
R
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------