@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
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Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MFRN2_HUMAN: (2015-12-08 )
MELEGRGAGGVAGGPAAGPGRSPGESALLDGWLQRGVGRGAGGGEAGACRPPVRQDPDSGPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWRAGK
Atome Classification :
(20 SA)
--.........10....--------....20.-.......30........40--.........50........60........70...---------.....80..--------......----------90...-.....100--..-..----...-------..110....--------------------.....120......-------.130..-------------------.....140.......150.......--160..-----------------------------------...---..---170-...-------------------.....180.......190..-------------...-..200-----..------.------....---------------------------------.210...------....---220-.----.......230-...-....240.......250.----....--..260.......270.......280.---......290.....-..300.--......310......--.320.--......330.......------340.......350.......----360..--------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MELEGRGAGGVAGGP--------AAGPGRS-P
G
E
S
A
L
L
D
G
W
L
Q
RGVGRG---AGGGEAGACRPPVRQDPDSGPDYEALPAG
A
T
V
T
T
---------
H
M
V
A
G
A
V
A
G
--------
I
L
E
H
C
V
----------MY
P
I
D
-
C
V
K
T
R
M
----
Q
S-LQ----PD
P
-------
A
A
R
--
Y
R
N
V
--------------------
L
E
A
L
W
R
I
I
RTEGLW-------RPMRG
L
-------------------
N
V
T
ATGAG
P
A
H
A
L
Y
F
A
C
Y
E
K
L
K
K
T
L
--
S
D
VIH-----------------------------------PGG---NS---HI--ANG-------------------
A
A
G
C
V
A
T
L
L
H
DAAM
N
P
A
E
V
V
-------------
K
Q
R
-
M
Q
M
Y------NS------
P
------
Y
H
R
V
---------------------------------
T
D
C
V
R
A
V
------
W
QNE---GA--G----
A
F
Y
R
S
Y
T
T
Q
L
-
T
MN-V
P
F
Q
A
I
H
F
M
T
Y
E
F
L
Q
E
HF----
N
P
Q
R--RYNPSS
H
V
L
S
G
A
C
A
G
A
V
A
A
AAT
T
P
L
D
---
V
C
K
T
L
LN
T
Q
E
S
LAL-NSHI
T
G
--
H
I
T
G
M
A
S
A
F
R
T
V
Y
Q
V--G
G
V
T
A
--
Y
F
RGV
Q
A
R
V
I
Y
QIPS
T
------
A
I
A
W
S
V
Y
E
F
F
K
Y
L
I
T
K
R
Q
E
E
----WRAGK--------------------
17
Fugue
84.44
17%
-60
- C5 -
1OKC
10
ADT1_BOVIN
A:
[2-293]
--------------------------------------------------------------------------------
D
Q
A
L
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F
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K
---------
D
F
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G
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A
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--------
A
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----------
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I
E
-
R
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L
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----
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-
Q
H
ASKQ
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-------
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--
Y
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I
--------------------
I
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-------
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N
-------------------
L
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--
L
G
G
V
D
-----------------------------------
R
H
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---
F
A
--
G
N
L
-------------------
A
S
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A
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C
F
V
Y
P
L
D
F
A
-------------
R
T
R
-
L
A
A
D
------
V
G
------
K
GAAQRE
F
T
G
L
---------------------------------
G
N
C
I
T
K
I
------
F
K
S
D
---
G
L
--
R
----
G
L
Y
Q
G
F
N
V
S
V
-
Q
G
I
-
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
----
P
D
P
K
--
N
V
H
I
I
V
S
W
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
---
T
V
R
R
R
M
M
M
Q
S
G
----
R
K
G
A
D
I
--
M
Y
T
G
T
V
D
C
W
R
K
I
A
K
D
--
E
G
P
K
A
--
F
F
K
G
A
W
S
N
V
L
R
G
M
G
G
A
------
F
V
L
V
L
Y
D
E
I
----------------------------------------
23
Fugue
83.74
13%
-63
- C3 -
4EEI
10
?
A:
[1-433]
MI
K
R
Y
D
V
A
E
I
S
K
I
W
A
D
E
--------
N
K
Y
A
K
M
L
-
E
V
E
L
A
I
L
E
A
L
E
D
R
M
V
P
K
G
-------
T
A
A
E
I
R
A
R
A
Q
------
I
R
P
E
R
V
D
E
I
E
K
V
T
K
---------
H
D
I
I
A
F
C
T
S
--------
I
A
E
Q
F
T
AETGKFFHFG
V
T
S
S
D
-
I
I
D
S
A
L
----
S
L
-
Q
I
----
R
D
S
-------
M
S
Y
--
V
I
K
D
--------------------
L
E
A
L
C
D
S
L
L
T
K
A
E
E
T
K
E
I
I
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M
G
R
S
H
G
M
-------------------
F
A
E
P
M
S
F
G
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K
F
L
G
A
Y
V
E
F
K
R
R
L
K
D
L
--
K
D
F
Q
K
-----------------------------------
D
G
L
---
T
V
---
Q
F
--
S
-
G
-------------------
A
V
G
N
Y
C
I
L
T
T
E
D
E
K
K
A
A
D
I
L
GLPVEEVSTQVIP
R
D
R
-
I
A
K
L
------
I
S
------
I
------
H
G
L
I
---------------------------------
A
S
A
I
E
R
L
A
V
E
I
R
H
L
H
R
S
---
D
V
--
F
----
E
V
Y
E
G
F
K
K
N
P
-
I
S
T
-
E
N
L
T
G
M
A
R
M
L
R
S
H
V
S
I
A
L
----
E
N
C
V
--
L
W
H
E
R
D
I
S
H
S
S
A
E
R
F
Y
L
P
D
N
F
G
I
M
V
Y
---
A
L
R
R
M
K
N
T
I
D
N
L
V
V
Q
R
D
I
I
E
D
--
R
V
R
S
T
S
A
Y
L
S
S
F
Y
L
H
--
F
L
V
A
N
TP
F
M
R
E
D
C
Y
K
I
V
Q
Q
V
E
S
F
------
S
K
K
L
Q
K
V
M
H
D
E
H
N
I
I
L
D
I
P
E
----
M
D
F
E
G
I
K
K
T
YLKE
I
D
H
V
F
D
R
S
V
KAR
18
Fugue
83.53
16%
-54
- C2 -
4KYI
5
?
A:
[4-544]
-G
S
E
I
S
K
T
E
A
G
Q
Y
S
V
S
A
P
E
H
K
G
L
V
L
S
G
G
G
A
K
G
-
I
S
Y
L
G
M
I
Q
A
L
Q
E
R
G
K
I
K
N
LT
H
V
S
G
A
S
A
G
A
M
T
A
S
I
L
A
V
G
M
D
I
K
D
I
K
K
L
I
E
G
L
D
I
T
K
LLDNSGVGF
R
A
R
G
D
R
F
R
N
--------
I
L
D
V
I
Y
----------
M
M
Q
M
K
K
H
L
E
S
V
Q
----
Q
P
-
I
P
----
P
E
Q
-------
Q
M
N
--
Y
G
I
L
K
Q
K
I
A
L
Y
E
D
K
L
S
R
A
GIVINN
V
D
D
I
I
N
L
T
K
S
V
K
D
L
-------
E
K
L
D
K
A
LNSIPT
E
L
K
G
A
KGEQLENP
R
L
T
L
G
D
L
G
R
L
R
E
L
L
P
E
E
N
K
H
L
I
K
N
L
--
S
V
V
V
T
NQTKH
E
L
E
R
Y
S
EDTTPQQS
I
A
Q
V
V
Q
W
S
G
AHPVLFV
P
G
R
---
N
A
KG
E
Y
I
--
A
D
G
GI
L
D
N
M
P
E
I
E
GLDREE
V
L
C
V
K
A
E
A
G
T
A
F
E
D
R
V
N
K
A
K
Q
S
A
-------------
M
E
A
-
I
S
W
F
------
K
A
------
R
------
M
D
S
L
VTSSVLNREKV
Y
Y
N
I
D
N
M
I
Y
I
N
TGEVTTTNTSP
T
P
E
Q
R
A
R
------
A
V
K
N
---
G
Y
--
D
----
Q
T
M
Q
L
L
D
S
H
K
Q
T
F
D
-
H
P
L
M
A
I
L
Y
I
G
H
D
K
L
K
D
A
L
IDEK
S
E
K
E
--
I
F
E
A
S
A
H
A
Q
A
I
L
H
L
Q
E
Q
I
V
K
E
M
N
D
G
D
YSS
V
Q
N
Y
L
D
Q
I
E
D
I
L
T
V
-
D
A
K
M
D
D
I
Q
K
E
K
A
F
A
L
C
I
K
Q
V
N
F
L
S
E
G
K
L
E
T
--
Y
L
N
K
V
E
A
E
A
K
A
A
A
E
P
S
WA
T
K
I
L
N
L
L
W
A
P
I
E
W
V
V
S
L
F
K
G
P
A
Q
D
----
F
K
-----------------------
7
HHSearch
81.63
18%
-61
- C5 -
1OKC
10
ADT1_BOVIN
A:
[4-293]
----------------------------------------------------------------------------------
A
L
S
F
L
K
---------
D
F
L
A
G
G
V
A
A
--------
A
I
S
K
T
A
----------
V
A
P
I
E
-
R
V
K
L
L
L
----
Q
V
-
Q
H
----
A
S
K
QISA---
E
K
Q
--
Y
K
G
I
--------------------
I
D
C
V
V
R
I
P
K
E
Q
G
F
L
-------
S
F
W
R
G
N
-------------------
L
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
Y
K
Q
I
F
--
L
G
G
V
D
RHK--------------------------------
Q
F
W
---
R
Y
---
F
A
--
G
N
L
-------------------
A
S
G
G
A
A
G
A
T
S
L
C
F
V
Y
P
L
D
F
A
-------------
R
T
R
-
L
A
A
D
------
V
G
KGAAQR
E
------
F
T
G
L
---------------------------------
G
N
C
I
T
K
I
------
F
K
S
D
---
G
L
--
R
----
G
L
Y
Q
G
F
N
V
S
V
-
Q
G
I
-
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
----
P
D
P
K
--
N
V
H
I
I
V
S
W
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
---
T
V
R
R
R
M
M
M
Q
S
G
R
K
G
----
A
D
I
--
M
Y
T
G
T
V
D
C
W
R
K
I
A
K
D
--
E
G
P
K
A
--
F
F
K
G
A
W
S
N
V
L
R
G
M
G
-
G
------
A
F
V
L
V
L
Y
D
E
I
---------------------------------------
2
PsiBlast_PDB
80.77
25%
-67
- C5 -
2C3E
4
ADT1_BOVIN
A:
[115-271]
-------------------------------------------------------------------------------------------------
N
L
A
S
G
G
A
A
G
--------
A
T
S
L
C
F
----------
V
Y
P
L
D
-
F
A
R
T
R
L
----
A
A
-
D
V
----
G
K
G
-------
A
A
Q
RE
F
T
G
L
--------------------
G
N
C
I
T
K
I
F
K
S
D
G
L
R
-------
G
L
Y
Q
G
F
-------------------
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
--
P
D
--------------------------------------
P
K
N
---
V
H
---
I
I
--
V
S
W
-------------------
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
T
V
-------------
R
R
R
-
M
M
M
Q
SGRKGA
D
I
------
M
------
Y
T
G
T
---------------------------------
V
D
C
W
R
K
I
------
A
K
D
E
---
G
P
--
K
----
A
F
F
K
G
A
W
S
N
V
-
L
R
G
-
M
G
G
A
F
V
L
V
L
Y
D
E
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
78.03
25%
-59
- C5 -
1OKC
7
ADT1_BOVIN
A:
[115-271]
-------------------------------------------------------------------------------------------------
N
L
A
S
G
G
A
A
G
--------
A
T
S
L
C
F
----------
V
Y
P
L
D
-
F
A
R
T
R
L
----
A
A
-
D
V
----
G
K
G
-------
A
A
Q
RE
F
T
G
L
--------------------
G
N
C
I
T
K
I
F
K
S
D
G
L
R
-------
G
L
Y
Q
G
F
-------------------
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
--
P
D
--------------------------------------
P
K
N
---
V
H
---
I
I
--
V
S
W
-------------------
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
T
V
-------------
R
R
R
-
M
M
M
Q
SGRKGA
D
I
------
M
------
Y
T
G
T
---------------------------------
V
D
C
W
R
K
I
------
A
K
D
E
---
G
P
--
K
----
A
F
F
K
G
A
W
S
N
V
-
L
R
G
-
M
G
G
A
F
V
L
V
L
Y
D
E
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
74.35
19%
-64
- C5 -
2LCK
-
UCP2_MOUSE
A:
[14-306]
--------------------------------------------------------------------------------------
T
V
---------
K
F
L
G
A
G
T
A
A
--------
C
I
A
D
L
I
----------
T
F
P
L
D
-
T
A
K
V
R
L
----
Q
I
-
Q
G
----
E
S
Q
G
L
V
R
T
A
A
S
A
Q
--
Y
R
G
V
--------------------
L
G
T
I
L
T
M
V
R
T
E
G
P
R
-------
S
L
Y
N
G
L
-------------------
V
A
G
L
Q
R
Q
M
S
F
A
S
V
R
I
G
L
Y
D
S
V
K
Q
F
Y
--
T
K
G
S
-------------------------------------
E
H
---
A
G
---
I
G
--
S
R
L
-------------------
L
A
G
S
T
T
G
A
L
A
V
A
V
A
Q
P
T
D
V
V
-------------
K
V
R
-
F
Q
A
Q
------
A
R
AGGGR-
R
------
Y
Q
S
T
---------------------------------
V
E
A
Y
K
T
I
------
A
R
E
E
---
G
I
--
R
----
G
L
W
K
G
T
S
P
N
V
-
A
R
N
-
A
I
V
N
C
A
E
L
V
T
Y
D
L
I
K
D
T
L
----
L
K
A
N
LM
T
D
D
L
P
C
H
F
T
S
A
F
G
A
G
F
C
T
T
V
I
A
S
P
V
D
---
V
V
K
T
R
Y
M
N
S
A
L
G
-----------
Q
Y
H
S
A
G
H
C
A
L
T
M
L
R
K
--
E
G
P
R
A
--
F
Y
K
G
F
M
P
S
F
L
R
L
G
S
W
N
------
V
V
M
F
V
T
Y
E
Q
L
K
R
A
L
M
A
A
Y
Q
S
----
R
E
A
P
F
--------------------
4
PsiBlast_PDB
70.85
24%
-64
- C5 -
4C9H
5
ADT2_YEAST
A:
[130-286]
-------------------------------------------------------------------------------------------------
N
L
A
S
G
G
A
A
G
--------
A
L
S
L
L
F
----------
V
Y
S
L
D
-
Y
A
R
T
R
L
A
A
DS-------------------
A
R
Q
--
F
N
G
L
--------------------
I
D
V
Y
K
K
T
L
K
S
D
G
V
A
-------
G
L
Y
R
G
F
-------------------
L
P
S
V
V
G
I
V
V
Y
R
G
L
Y
F
G
M
Y
D
S
L
K
---------------------------------------------------------
L
--
A
S
F
-------------------
L
L
G
W
V
V
T
T
G
A
S
T
C
S
Y
P
L
D
T
V
-------------
R
R
R
-
M
M
M
T
------
S
G
QAV---
K
------
Y
D
G
A
---------------------------------
F
D
C
L
R
K
I
------
V
A
A
E
---
G
V
--
G
----
S
L
F
K
G
C
G
A
N
I
-
L
R
G
-
V
A
G
A
G
V
I
S
M
Y
D
Q
L
Q
M
I
L
F
----
G
K
K
F
--
K
--------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
69.85
22%
-53
- C5 -
1OKC
9
ADT1_BOVIN
A:
[110-293]
-----------------------------------------------------------------------------------
R
Y
F
A
G
---------
N
L
A
S
G
G
A
A
G
--------
A
T
S
L
C
F
----------
V
Y
P
L
D
-
F
A
R
T
R
L
----
A
A
-
D
V
----
G
K
G
AA-----
Q
R
E
--
F
T
G
L
--------------------
G
N
C
I
T
K
I
F
K
S
D
G
L
R
-------
G
L
Y
Q
G
F
-------------------
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
--
P
D
P
K
--------------------------------------
N
---
V
H
---
I
I
--
V
S
W
-------------------
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
T
V
-------------
R
R
R
-
M
M
M
Q
------
S
G
RKGADI
M
------
Y
T
G
T
---------------------------------
V
D
C
W
R
K
I
------
A
K
D
E
---
G
P
--
K
----
A
F
F
K
G
A
W
S
N
V
-
L
R
G
-
M
G
-
G
A
F
V
L
V
L
Y
D
E
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
65.56
26%
-48
- C5 -
2LCK
-
UCP2_MOUSE
A:
[114-296]
-----------------------------------------------------------------------------------
A
G
I
G
S
---------
R
L
L
A
G
S
T
T
G
--------
A
L
A
V
A
V
----------
A
Q
P
T
D
-
V
V
K
V
R
F
----
Q
A
Q
A
R
----
A
G
G
-------
G
R
R
--
Y
Q
S
T
--------------------
V
E
A
Y
K
T
I
A
R
E
E
G
I
R
-------
G
L
W
K
G
T
-------------------
S
P
N
V
A
R
N
A
I
V
N
C
A
E
L
V
T
Y
D
L
I
K
D
T
L
LK
A
N
L
M
T
-----------------------------------
D
D
L
---
P
C
---
H
F
T
S
A
F
G
-------------------
A
G
F
C
T
T
V
I
-----
A
S
P
V
D
V
V
-------------
K
T
R
Y
M
N
S
A
------
L
G
------
Q
------
Y
H
S
A
---------------------------------
G
H
C
A
L
T
M
------
L
R
K
E
---
G
P
--
R
----
A
F
Y
K
G
F
M
P
S
F
-
L
R
L
-
G
S
W
N
V
V
M
F
V
T
Y
E
Q
L
K
R
A
L
----
M
A
A
Y
--
Q
S
R
E
A
P
F
--------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
64.95
10%
-58
- C4 -
2D0T
4
I23O1_HUMAN
A:
[15-406]
----
S
K
E
Y
H
I
D
E
E
V
G
F
A
--------
L
P
N
P
Q
E
N
L
P
D
F
Y
N
D
W
M
F
I
A
K
H
L
P
D
L
I
---
E
S
G
Q
L
R
E
R
V
E
K
L
N
M
L
S
I
D
H
L
T
D
H
K
S
Q
R
L
A
R
L
V
L
G
---------
C
I
T
M
A
Y
V
W
G
KGHGDVRK
V
L
P
R
N
I
----------
A
V
P
Y
C
-
Q
L
S
K
K
L
----
E
--------
L
P
P
-------
I
L
V
--
Y
A
D
C
--------------------
V
L
A
N
W
K
K
K
D
P
N
K
P
L
-------
T
Y
E
N
M
D
-------------------
V
L
F
S
F
R
D
G
D
C
S
K
G
F
F
L
V
S
L
L
V
E
I
A
A
--
A
S
A
I
K
V
I
---------------------------------
P
T
V
---
F
K
---
A
M
--
Q
M
Q
-------------------
E
R
D
T
L
L
K
A
L
L
E
I
A
S
C
L
E
K
A
L
-------------
Q
V
F
-
H
Q
I
H
------
D
H
------
V
N
P
K
A
F
-
F
S
V
L
---------------------------------
R
I
Y
L
S
G
W
------
K
G
N
P
---
Q
L
SD
G
----
L
V
Y
E
G
F
W
E
D
P
-
K
E
F
-
A
G
G
S
A
G
Q
S
S
V
F
Q
C
F
D
V
L
L
----
G
I
Q
Q
--
T
A
G
G
G
-----
H
A
A
Q
F
L
Q
D
M
R
R
Y
M
P
P
A
---
H
R
N
F
L
C
S
L
E
S
N
P
S
V
-
R
E
F
V
L
S
----
K
G
D
A
G
L
R
E
A
Y
D
A
C
--
V
K
A
L
V
--
S
L
R
S
Y
H
L
Q
I
V
T
K
Y
I
L
I
------
P
A
S
Q
G
G
T
D
L
M
N
F
L
K
T
V
R
S
T
T
----
E
K
S
L
L
KEG-----------------
9
HHSearch
63.36
24%
-48
- C5 -
2LCK
-
UCP2_MOUSE
A:
[114-302]
-----------------------------------------------------------------------------------
A
G
I
G
S
---------
R
L
L
A
G
S
T
T
G
--------
A
L
A
V
A
V
----------
A
Q
P
T
D
-
V
V
K
V
R
F
----
Q
A
-
Q
A
----
R
A
G
G------
G
R
R
--
Y
Q
S
T
--------------------
V
E
A
Y
K
T
I
A
R
E
E
G
I
R
-------
G
L
W
K
G
T
-------------------
S
P
N
V
A
R
N
A
I
V
N
C
A
E
L
V
T
Y
D
L
I
K
D
T
L
--
L
K
A
N
L
------------------------------------
M
T
---
D
D
---
L
P
--
C
H
F
-------------------
T
S
A
F
G
A
G
F
C
T
T
V
I
A
S
P
V
D
V
V
-------------
K
T
R
-
Y
M
N
S
------
A
L
G-----
Q
------
Y
H
S
A
---------------------------------
G
H
C
A
L
T
M
------
L
R
K
E
---
G
P
--
R
----
A
F
Y
K
G
F
M
P
S
F
-
L
R
L
-
G
S
W
N
V
V
M
F
V
T
Y
E
Q
L
K
R
A
L
----
M
A
A
Y
--
Q
S
R
E
A
P
F
--------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
59.95
23%
-64
- C5 -
4C9Q
3
ADT3_YEAST
A:
[21-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
Q
--
E
T
N
F
A
I
N
F
L
M
G
G
V
S
A
A
I
A
K
T
A
A
S
P
I
E
---
R
V
K
I
L
I
Q
N
Q
D
E
M
I
K
-
Q
G
T
L
D
K
--
K
Y
S
G
I
V
D
C
F
K
R
T
A
K
Q
--
E
G
L
I
S
--
F
W
R
G
N
T
A
N
V
I
R
Y
F
P
T
Q
------
A
L
N
F
A
F
K
D
K
I
K
L
M
F
G
F
K
K
E
-G
Y
G
K
W
F
A
G
N
--------------------
5
PsiBlast_PDB
58.35
23%
-63
- C5 -
4C9J
3
ADT3_YEAST
A:
[25-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
N
F
A
I
N
F
L
M
G
G
V
S
A
A
I
A
K
T
A
A
S
P
I
E
---
R
V
K
I
L
I
Q
N
Q
D
E
M
I
K
-
Q
G
T
L
D
K
--
K
Y
S
G
I
V
D
C
F
K
R
T
A
K
Q
--
E
G
L
I
S
--
F
W
R
G
N
T
A
N
V
I
R
Y
F
P
T
Q
------
A
L
N
F
A
F
K
D
K
I
K
L
M
F
G
F
K
K
E
E
G
Y
G
K
W
F
A
G
N
--------------------
19
Fugue
47.04
22%
-24
- C5 -
2GSV
-
YVFG_BACSU
A:
[3-69]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
F
------
S
V
------
P
------
Y
F
I
E
---------------------------------
N
L
K
Q
H
I
E
M
-----
N
Q
S
E
D
K
I
H
A
M
-
N
----
S
Y
Y
R
S
V
V
S
T
L
-
V
Q
D
Q
L
T
K
N
A
V
V
L
K
R
I
Q
H
L
D
E
A
Y
----
N
K
V
K
--
R
G
-------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
43.26
23%
5
- C5 -
3J9X
-
?
A:
[29-80]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
V
S
P
V
A
-------------
Q
Q
N
-
F
Q
T
N
------
V
P
------
K
------
F
T
S
V
---------------------------------
N
E
N
V
S
A
V
------
L
T
Q
Y
---
G
I
--
T
G
P
N
R
A
I
Y
Q
G
F
G
L
K
V
-
A
R
A
-
L
N
R
I
G
S
G
P
A
L
V
N
M
I
N
G
L
K
----
G
Y
Y
I
--
S
A
F
N
A
N
P
Q
V
L
D
A
V
V
N
I
I
T
G
S
P
T
G
Y
V
S
-------------------------------------------------------------------------------------------------------------------------
12
HHSearch
42.43
11%
-38
- C5 -
3F2E
1
?
A:
[8-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
A
V
--------------------
A
E
Q
V
S
A
V
L
S
Q
Y
G
I
T
-------
G
P
N
R
A
I
-------------------
Y
Q
G
F
G
L
K
V
A
R
A
L
N
R
L
G
G
G
P
A
L
V
N
M
I
--
N
G
L
K
A
Y
Y
I
S
AFNAN--------------------------
P
T
V
---
L
D
---
A
V
--
T
D
I
-------------------
I
T
G
S
P
T
G
Y
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
39.69
19%
-27
- C5 -
3F2E
1
?
A:
[8-59]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
A
V
---------------------------------
A
E
Q
V
S
A
V
------
L
S
Q
Y
---
G
I
--
T
----
G
P
N
R
A
I
Y
Q
G
F
-
G
L
K
-
V
A
R
A
L
N
R
L
G
G
G
P
A
L
V
N
M
I
----
N
G
L
K
--
A
Y
Y
I
S
A
F
N
A
N
P
T
V
L
D
A
V
T
D
I
I
T
G
S
P
T
---
G
Y
V
S
------------------------------------------------------------------------------------------------------------------
14
HHSearch
32.56
19%
31
- C5 -
3VJJ
-
?
A:
[273-308]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
A
T
F
D
N
Y
P
F
D
---
L
L
R
F
Q
L
S
S
L
I
S
----------------
T
P
A
L
I
R
E
K
I
A
K
--
E
G
L
F
K
--
I
I
T
T
V
L
F
R
G
I
N
G
S
E
S
F
------
L
N
I
K
R
Y
R
K
F
K
T
R
I
V
G
N
V
D
C
V
----
I
K
S
D
F
--------------------
16
HHSearch
26.11
13%
58
- C5 -
3TGU
1
?
G:
[33-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
P
N
--
V
W
R
R
F
S
S
Q
V
F
K
V
A
P
P
F
------
L
G
A
Y
L
L
Y
S
W
G
T
Q
E
F
E
R
L
K
R
K
----
N
P
A
D
Y
--------------------