Atome 2 Filter

@TOME V2.2
(Nov 2016)

Ref. - Doc.

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Values color: [ Good | Correct | Middling | Bad ]

Sequence color : MutatedHelixStrandConserved

Query sequence : SPX2_HUMAN: (2015-12-12 )
MRSSLAPGVWFFRAFSRDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGSGYKEI

Atome Classification :

	(20 SA)									-.........10.....---...20....-....30........40........50........60........70........80........90........100.......110.......120--........130.-......140-.......150.....-..----160.......170..--....----.180.-...-...190---.......200.-.---------------------------.--.....210.......220.......230.......240.......250.......260.......270.......280.......290.......300..--.....310.......320...-.---...330.......340.......350....--...360.......--370--.......380.......390.......400.......410......--..420.......430.......440.--.-.....450--.....-...460.......470.......480.......490.......500
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		-MRSSLAPGVWFFRAFS---RDSWFRGLI-LLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAG---MLLSGLFTSLFG-LGYFWNIHE-LWYFVVIQVCNGLVQ-TT----GWPSVVTCVGNWFGK--GKRG----FIMGI-WNS-HTSVGN---ILGSLIAG-IW-V---------------------------N--GQWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCL--LFAKLVSYTFLYWLPLYIANV-A---HFSAKEAGDLSTLFDVGGIIGGIVAGLVSD--YTNGRATTCCVML--ILA--APMMFLYNYIGQDGIASSIVMLIICGGLVNGPYALITTA-VSADLG--THKSLKGNAKALSTVTAIIDGTGSIG--A-ALGPLLA---GLISP-TGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGSGYKEI
21	Fugue	96.20	21%	-113	- C2 -	1PW4	-	GLPT_ECOLI	A:[5-451]	FKPAPHKARLPAAEIDP---TYRRLRWQI-FLGIFFGYAAYYLVRKNFALAMPYLV---------------------------EQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAG---LILAAAVMLFMG-FVPWAT-SS-IAVMFVLLFLCGWFQ-GM----GWPPCGRTMVHWWSQ--KERG----GIVSV-WNC-AHNVGG---GIPPLLFL-LG-M---------------------------AWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDTAKQIFMQY----------------------------------VLPNKLLWYIAIAN--VFVYLLRYGILDWSPTYLKEV-K---HFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFM--TLV--TIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLH-ALELAP----KKAAGTAAGFTGLFGYLGGSVAAS--A-IVGYTVD-------F-FGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQELVP----
10	HHSearch	94.71	22%	-125	- C2 -	1PW4	-	GLPT_ECOLI	A:[7-445]	-----PAPHKARLPAAEIDPTYRRLRWQI-FLGIFFGYAAYYLVRKNFALAMPYLV-E----------------------QGFSR----GDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAG---LILAAAVMLFMG-FVPWA-TSS-IAVMFVLLFLCGWFQ-GM----GWPPCGRTMVHWWSQ--KERG----GIVSV-WNC-AHNVGG---GIPPLLFL-LGMAW--------------------------F--NDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKND----------------------------------TAKQIFMQYVLPNKLLWYIAIAN--VFVYLLRYGILDWSPTYLKEV-K---HFALDKSSWAYFLYEYAGIPGTLLCGWMSD--KVFRGNRGATGVFFMTLV--TIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLH-A-LELA---PKKAAGTAAGFTGLFG------YLG--GSVAASAIV---GYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQELVP----
1	PsiBlast_PDB	90.93	22%	-124	* C2 *	1PW4	-	GLPT_ECOLI	A:[27-438]	-------------------------RWQI-FLGIFFGYAAYYLVRKNFALAMPYLVEQG-----------------------FSRGDLGFALSGIS----IAYGFSKFIMGSVSDRSNPRVFLPAG---LILAAAVMLFMG-FVPWATSSI-AVMFVLLFLC-GWFQ-GM----GWPPCGRTMVHWWSQ--KERG----GIVSV-WNC-AHNVGGGIPPLLFLLGM-AW-F---------------------------N---DWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEY-----KND-------------------------------TAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEV-K---HFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFM--TLVTIATIVYWMNPAGNPTV--DMICMIVIGFLIYGPVMLI---------G--LHALELAPKKAAGTAAGFTGLFGYLGGSV-AASAIVG---YTVDF-FGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQELVP----
29	Fugue	66.24	15%	-109	- C2 -	3O7Q		FUCP_ECOLI	A:[22-435]	--RSYIIPFALLCSLFF---LWAVANNLN-DILLPQFQQAFTLT--------------------------------------------NFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITG---LFLYALGAALFW-PAAEIMNYT-LFLVGLFIIAAGLGCLET----AANPFVTVLGP---E--SSGH----FRLNL-AQT-FNSFGA---IIAVVFGQ-SL-ILSNV-----------------------P--HQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNH------------SDAKQGSFSASLSRLARIRHWRWAVLAQFCY--VGAQTACWSYL--IRYAVEEI-P---GMTAGFAANYLTGTMVCFFIGRFTGTWLIS--RFAPHKVLAAYAL--IAM--ALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGI-------------KNLGQDTKYGSSFIVM----TIIG--G-GIVTPVM---GFVSD-AA----------GNIPTAELIPALCFAVIFIFARFRSQT------
26	Fugue	65.14	13%	-99	- C2 -	2GFP	-	EMRD_ECOLI	A:[9-383]	--LLLMLVLLVAVGQMA---QTIYIPAIA-DMARDL-------------------------------------------------NVREGAVQSVMGAYLLTYGVSQLFYGPISDRVG-----RRP---VILVGMSIFMLA-TLVAVTTSS-LTVLIAASAMQGMGT-GV----GGVMARTLPRDLYER--TQLR----HANSL-LNM-GILVSP---LLAPLIGGLLD-T---------------------------M--WNWRACYLFLLVLCAGVTFSMARWMPE-------------TRPVDAPRTRLLTSY-----------------------KTLFGNSGFNCYLLMLIGGLAG--IAAFEACSGVLM-GAVLGLSS-M---TVSILFILPIPAAFFGAWFAGRPN----------KRFSTLMWQSV--ICC--LLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLA-TSGAME--PFPFLAGTAGALVGGLQNIGSG------------VLA---SLSAM-LPQTGQGSLGLLMTLMGLLIVLCWLPL------------------
22	Fugue	64.98	12%	-108	- C2 -	1PV6	-	LACY_ECOLI	A:[1-417]	--MYYLKNTNFWMFGLF---FFFYFFIMG-AYFPFFPIWLHDINHIS-----------------------------------------KSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWI---ITGMLVMFAPFF-IFI-FGPLL-QYNILVGSIVGGIYL-GF----CFNAGAPAVEAFIEKVSRRSN----FEFGR-ARM-FGCVGW---ALGASIVG-IM-F---------------------------T--INNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFS----------------------------------LKLALELFRQPKLWFLSLYV--IGVSCTYDVFDQQFANFFTSF-F---ATGEQGTRVFGYVTTMGELLNASIMFFAPL--IINRIGGKNALLL--AGT--IMSVRIIGSS----FATSALEVVILKTLHMFEVPFLLVG-CFKYIT--SQFEVRFSATIYLVCF---CFFKQLA--M-IFMSVLA---GNMYE-SIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA--
14	HHSearch	56.54	14%	-100	- C2 -	2CFQ	-	LACY_ECOLI	A:[38-396]	--------------------------------------------------------------------------------NHISK----SDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFI-F-----GPLLQYNILVGSIVGGIYL-GFCFNAGAPAVEAFIEKVS----RRSN----FEFGR-ARM-FGCVGW---ALGASIVG-IM-F---------------------------T--INNQFVFWLGSGCALILAVL-LFFAKTDAPSSATV-A--N--A----VGA-N----------HS---------AF----SLKLALELFRQPKLWFLSLYV--IGVSCTYDVFDQQFANFFTSF-FATGEQGTRVFGYVTTMGELLNASIMFFAPLIIN--RIGGKNALLLAGT--IMS--VRII-GSSFA-T-SALEVVILKTLHMFEVPFLLVGCFKY-I-TSQF---EVRFSATIYLVCF-----CFFKQLA--M-IFMSVLA---GNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA---
16	HHSearch	56.07	17%	-141	- C2 -	3WDO	-	?	A:[12-178]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWGLGTVF--SLRMLGMFMVLPVLTTYGMAL-Q---GASEALIGIAIGIYGLTQAVFQIPFGLLSD--RIGRKPLIVGGLA--VFA--AGSVIAA-LS-D-SIWGIILGRALQGSGA--IAAAVMA--LLSDLT---REQNRTKAMAFIGV------SFGIT--F-AIAMVLG---PIITHKLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFS
30	Fugue	51.80	13%	-106	- C1 -	1N25	-	LT_SV40	A:[7-368]	-KQVSWKLVTEYAMETK---CDD----------VLLLLGMYLEFQYS--------FEMCLKCIKKEQPSHYKY-------HEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLT---NRFNDLLDRMDIMFGSTGSADI-EEWMAGVAWLHCLLP-------KMDSVVYDFLKCMVY--NIPKKRYWLFKGP-IDSGKTTLAA---ALLELCGG-KA-L---------------------------N--VNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIF------PPGIVTMNEYSVPKTLQAR------FVKQIDFRPKDYLKHCLERS-E---FLLEK--------------------RIIQS-------GIALLLML--IWY--RP---------------------------------------------------------------VAEFAQSIQ--S-RIVEWKE---RLDKE-FS-----------------------LSVYQKMKFNVAMGIGVLD-
12	HHSearch	50.06	16%	-81	- C2 -	2GFP	-	EMRD_ECOLI	A:[38-359]	--------------------------------------------------------------------------------LNVRE----GAVQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVG---MSIFMLATLVAV-T-----TSS-LTVLIAASAMQGMGT-GV----GGVMARTLPRDLYER--TQLR----HANSL-LNM-GILVSP---LLAPLIGG-LLDT---------------------------M--WNWRACYLFLLVLCAGVTFSMARWMPETRPVD------AP-------R-T-R-----------L----------------LTSYKTLFGNSGFNCYLLML--IGGLAGIAAFEACSGVLMGAV-L---GLSSMTVSILFILPIPAAFFGAWFAGRPNK--RFSTLMWQSVICC--LLA--GLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSG-A-MEPF---P-FLAGTAGALVGG------LQNIG--S-GVLASLS---AMLPQ-TGQGSLGLLMTLMGLLIVLCWLPL---------------------
11	HHSearch	49.73	15%	-97	- C2 -	3O7Q		FUCP_ECOLI	A:[22-329]	------------------------RSYIIPFALLCSLFFLWAVANNLNDILLPQFQQA----------------------FTLTN----FQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITG---LFLYALGAALFW-PAA--EIMN-YTLFLVGLFIIAAGL-GC----LETAANPFVTVLGPE--SSGH----FRLNL-AQT-FNSFGA---IIAVVFGQ-SL-ILSNVPHQSQDVLDKMSPEQLSAYKHSLV--LSVQTPYMIIVAIVLLVALLI-M-LTKFPALQSD---NHS-------DAK-Q----------GS---------------FSASLSRLARIRHWRWAVLAQ--FCYVGAQTACWSYLIRYAVEEIP---GMTAGFAANYLTGTMVCFFIGRFTGTWLIS--RFAPHKVLAAYAL--IAM--ALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKN-LGQDTK--YGSSFIVMTIIGGGIVTPVMGFVSDA--A-GNIPTAE---LIPAL-CFAVIFIFARFRSQT------------------------------
19	HHSearch	38.66	17%	-92	- C2 -	3O7Q		FUCP_ECOLI	A:[39-176]	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVANNLNDILLPQFQQ-A-F---TLTNFQAGLIQSAFYFGYFIIPIPAGILMK--KLSYKAGIITGLF--LYA--LGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPF-V-TVLG---PESSGHFRLNLAQT------FNSFG--A-IIAVVFG---QSLIL-SNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVA
9	PsiBlast_PDB	36.89	30%	-112	- C2 -	4PYP		GTR1_HUMAN	A:[71-201]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFSVGGMIGSFSVGLFVN--RF-GRRNSMLMMN--LLA--FVSAVL---MGFSKLGKSFEMLIL-GRFIIGVYCGLTTGFVPMYVGEVSPTALRG---ALGTLH-------QLG--I-VVGILIAQVFGLDSI-MGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRA
18	HHSearch	35.87	14%	-111	- C2 -	2GFP	-	EMRD_ECOLI	A:[27-172]	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YIPAIADMA-RD-L---NVREGAVQSVMGAYLLTYGVSQLFYGPISD--RVGRRPVILVGMS--IFM--LATLV-AVTT-S-SLTVLIAASAMQGMGTGVGGVMARTL-P-RDLY---ERTQLRHANSLLNM------GILVS--P-LLAPLIG---GLLDTMWNWRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTL
13	HHSearch	34.72	11%	-119	- C2 -	3WDO	-	?	A:[41-188]	--------------------------------------------------------------------------------QGASE----ALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGG---LAVFAAGSVIAA-L-----SDS-IWGIILGRALQGSGA-------IAAAVMALLSDLTRE--QNRT----KAMAF-IGV-SFGITF---AIAMVLGP-IITH---------------------------K--LGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLNFGIMCLHMLLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAF--GSVVPFIIYAEVKRKMKQVFV-F---CVGLIVVAEIVLWNAQTQFWQLVVGVQLFF--VAFNLMEALLPSL--ISK--ESPAGYKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQ-GVFLAG--AMLAAVWLAVASTMKEPPYVSSLRIE--I-PADIAAN---EALKV-RLLETEGVKEVLIAEEEHSAYVKIDSKVTNRFEVEQAIRQAL---
17	HHSearch	32.34	12%	-85	- C2 -	1PW4	-	GLPT_ECOLI	A:[289-428]	-----------------------------------------------------------------------------------------DKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATG---VFFMTLVTIATI-VYWMNPAGN-PTVDMICMIVIGFLI-YG----PVMLIGLHALELAPK--KAAG----TAAGF-TGL-FGYLGGS--VAASAIVG-YTVD---------------------------F--FGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQELVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15	HHSearch	32.24	13%	-94	- C2 -	2CFQ	-	LACY_ECOLI	A:[259-396]	-----------------------------------------------------------------------------------------RVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLA---GTIMSVRIIGSS-F-----ATS-ALEVVILKTLHMFEV-PF----LLVGCFKYITSQFEV--RFSA----TIYLVCFCF-FKQLAM---IFMSVLAG-NMYE---------------------------S--IGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5	PsiBlast_PDB	31.42	28%	-21	- C3 -	1N21	-	BPPS_SALOF	A:[33-86]	-----------------------------------------HLDRKAELIVQVRI--LLKEKMEPVQQLELIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFHKMDLYFTALGFRLLRQHGFNISQ---DVFNCFKNEKGI-DFKASLAQD-TKGMLQLYEASFLLR-KG----EDTLELAREFATKCL--QKKL----DDENL-LLW-IRHSLD---LPLHWRIQ-SV-E---------------------------A--RWFIDAYARRPDMNPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRDRLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYG--TLDELELFTDTFKRWDTESIT-R---LPYYMQLCYWGVHNYISDAAYDILKEHGFF--CLQYLRKSVVDLV--EAY--FHEAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFTF-ANASHD--TAVIDSLYQYHDILCLAGIILRLPDD--L-GTSYFEL---ARGDV-PKTIQCYMKETNASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPD
4	PsiBlast_PDB	30.00	28%	-23	- C3 -	1N20	-	BPPS_SALOF	A:[33-86]	-----------------------------------------HLDRKAELIVQVRI--LLKEKMEPVQQLELIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFHDLYFTALGFRLLRQHGFNISQDV---FNCFKNEKGIDF-KASLAQDTK-GMLQLYEASFLLRKG-ED----TLELAREFATKCLQK--KLDD----ENLLL-WIR-HSLDLP---LHWRIQSV-EA-R---------------------------W--FIDAYARRPDMNPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRDRLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYGTL--DELELFTDTFKRWDTESITRL-P---YYMQLCYWGVHNYISDAAYDILKEHGFFCL--QYLRKSVVDLVEA--YFH--EAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFTFAN-ASHDTA--VIDSLYQYHDILCLAGIILRLPDDLG--T-SYFELAR---GDVPK-TIQCYMKETNASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPDGM
7	PsiBlast_PDB	29.43	28%	-25	- C3 -	1N23	-	BPPS_SALOF	A:[33-86]	-----------------------------------------HLDRKAELIVQVRI--LLKEKMEPVQQLELIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFMDLYFTALGFRLLRQHGFNISQDV---FNCFKNEKGIDF-KASLAQDTK-GMLQLYEASFLLRKG-ED----TLELAREFATKCLQK--KLDE----IDENL-LLW-IRHSLD---LPLHWRIQ-SV-E---------------------------A--RWFIDAYARRPDMNPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRDRLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYG--TLDELELFTDTFKRWDTESIT-R---LPYYMQLCYWGVHNYISDAAYDILKEHGFF--CLQYLRKSVVDLV--EAY--FHEAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFTF-ANASHD--TAVIDSLYQYHDILCLAGIILRLPDD--L-GTSYFEL---ARGDV-PKTIQCYMKETNASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPD