@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : T0846: (2014-07-08 )
MAHHHHHHFISPQKIVPLSYNEFIRKVVSDHSIQEQEKEIRRLSQIVFGNQNQLANQLSQIHENPSFTKIISNTLTNSPESFAKLAGSKTFGIKNSKRKQAEKNISKLVEAIHKYADAVENSMGNIIKNHNAEQKRLAQSVELPSD
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------.........10..-----......20..----...------...-30........40.----.......50.--------...----------....60-.-..---...---..70----.....-.-..80.......-.90......-..100........110..------.....120....-----...130...---...-..140....------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------MAHHHHHHFI
S
P
Q
-----
K
I
V
PL
S
Y
N
E
F
----
I
R
K
------
V
V
S-DH
S
I
Q
E
Q
E
K
E
I
R
R
----
L
S
Q
I
VFG
N
Q
N
--------
Q
L
A
----------
N
Q
L
S
Q
I
-H-EN---P
S
F
---
T
K
I
I
----
S
N
TLT-N-
S
P
E
S
F
A
K
LAGS-KTFGIKN
S
K
-
R
K
Q
-
A
E
K
N
I
S
K
L
V
E
A
I
H
K
------
Y
A
D
A
V
E
N
S
M
G
N
I
-----
I
KNH
N
-
A
E
Q
---
K
R
L
-
A
Q
SVELPSD------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
Fugue
71.36
12%
1
- C3 -
1R5I
-
?
D:
[3-216]
---------------------------------------------------------------------------------------------------SM
K
L
R
V
E
N
P
K
K
A
Q
K
H
-----
F
V
Q
N
L
N
N
V
V
F
----
T
N
K
------
E
L
E
-
D
I
Y
N
L
S
N
K
E
E
T
K
E
----
V
L
K
L
F
K
L
K
V
N
--------
Q
F
Y
----------
R
H
A
F
G
I
-
V
-
N
D
---
Y
--------------
N
G
L
L
-
E
-
Y
K
E
I
F
N
M
M
F
L
K
-
L
S
V
V
F
D
T
Q
R
-
K
E
A
N
N
V
E
Q
I
K
R
N
I
A
I
L
D
E
------
I
M
A
K
A
D
N
D
L
S
Y
F
-----
I
S
Q
N
K
-
N
F
Q
---
E
L
W
-
D
K
A
V
K
L
T
K
E
M
K
I
K
L
K
GQKLDLRDG
E
V
A
I
N
K
V
R
E
L
FGSD
K
N
V
K
E
L
W
W
F
R
S
L
L
V
K
G
V
Y
L
I
K
R
Y
Y
E
GDIELKTTS
D
F
A
K
A
V
F
ED------------------------------------------------------------------------------------------------
6
Fugue
69.70
20%
23
- C3 -
1RW2
-
A:
[1-152]
-----------------------------------------------------------------------------------------------------
M
H
H
H
H
H
H
K
L
K
T
E
Q
-----
G
G
A
H
F
S
V
S
S
L
AEGS
V
T
S
------
V
G
S
-
V
N
P
A
E
N
F
R
V
L
V
K
Q
----
K
K
A
S
F
E
E
A
S
N
--------
Q
L
I
----------
N
H
I
E
Q
F
-
L
-
D
------------------
T
N
E
T
P
-
Y
-
F
M
K
S
I
D
C
I
R
A
F
-
R
E
E
A
I
K
F
S
E
-
E
Q
R
-
F
N
N
F
L
K
A
L
Q
E
K
V
E
I
KQL
N
H
F
W
E
I
V
V
Q
D
G
I
T
L
I
-----
T
K
E
E
A
-
S
G
S
SVT
A
E
E
-
A
K
K
F
L
A
P
K
D
K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
Fugue
68.75
21%
37
- C3 -
2K48
-
V_SV5
A:
[1-107]
-----------------------------------------------------------------------------------------------------
M
H
H
H
H
H
H
G
K
P
I
P
N
-----
P
L
L
G
L
D
S
T
E
----------------------------------------------------------------------------
N
---
L
Y
F
---
Q
G
I
D
----
P
F
T
M
S
-
T
-
L
Q
E
L
Q
E
N
I
T
A
H
E
Q
Q
L
V
T
A
R
Q
K
-
L
K
D
-
A
E
K
A
V
E
V
D
P
D
D
V
N
K
------
S
T
L
Q
N
R
R
A
A
V
S
T
-----
L
E
T
K
L
-
G
E
L
---
K
R
Q
-
L
A
D
L
V
A
A
Q
K
L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
67.53
22%
-34
- C3 -
4CI0
1
?
A:
[2-386]
S
E
R
I
V
I
S
PTSRQE
G
H
A
E
L
V
M
E
V
D
DEGIVT
K
G
R
Y
F
S
ITPVRG
L
E
K
M
V
TGKAPET
A
P
V
M
V
Q
R
ICGVC
P
I
P
H
T
L
A
S
V
E
A
I
D
D
S
L
DIEVP
K
A
G
R
L
L
R
E
L
T
L
A
A
H
H
V
N
S
H
A
I
H
H
F
L
I
A
P
-----
D
F
V
P
--------------------------
E
N
L
M
A
D
A
I
N
S
----
V
S
E
I
R
-
K
N
A
Q
--------
Y
V
V
----------
D
M
V
A
G
E
-
G
-
I
H
---
P
S
D
---
V
R
I
----------------------
G
G
-
M
A
D
N
I
T
E
L
A
-
R
K
R
-
L
Y
A
R
L
K
Q
L
K
P
K
V
N
E
------
H
V
E
L
M
I
G
L
I
E
D
K
GLPEG
L
G
V
H
N
---
Q
---
P
T
L
-
A
-
S
H
Q
I
Y
G
D
RTKFDLDR
F
T
E
I
M
PESWYDD
P
E
I
A
K
R
AC
S
T
I
P
L
Y
DG
R
N
V
E
V
G
P
R
A
R
M
V
E
FQGFKERG
V
V
A
Q
H
V
A
R
A
L
E
M
K
T
A
L
S
R
A
I
E
I
L
D
E
LDTSAPV
R
A
D
F
D
ERGTG
K
L
G
I
G
A
I
E
A
PR
G
L
D
V
H
M
A
K
V
E
NGKIQ
F
Y
S
A
L
V
P
T
T
W
N
I
P
T
M
G
P
A
T
EGFHHEY
G
P
H
V
I
R
A
Y
DPCLSCATH
5
Fugue
66.56
12%
-31
- C3 -
3LS0
-
?
A:
[32-146]
----------------------------------------------------------------------------------------------------------------------------
T
Y
S
-----------------------
P
E
K
I
A
Q
L
Q
V
----
Y
V
N
P
I
A
V
A
R
D
--------
G
M
E
----------
K
R
L
Q
G
L
-
I
-
A
D
QN
W
V
D
T
---
Q
T
Y
I
----
H
G
P
L
G
-
Q
-
L
R
R
D
M
L
G
L
A
S
S
-----
L
L
P
K
D
-
Q
D
K
-
A
K
T
L
A
K
E
V
F
G
H
L
E
R
------
L
D
A
A
A
K
D
R
N
G
S
Q
-----
A
K
I
Q
Y
-
Q
E
A
---
L
A
D
-
F
D
S
F
L
N
L
L
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
60.26
26%
-0
- C3 -
3GFV
-
YCLQ_BACSU
A:
[100-170]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
----
S
A
R
Q
S
-
E
-
S
Y
K
E
F
S
K
I
A
P
T
-
I
Y
L
G
V
D
T
A
K
-
Y
M
E
-
S
F
K
S
D
A
E
T
I
G
K
I
F
D
------
K
E
D
K
V
K
D
E
L
A
N
I
-------
D
H
S
I
A
D
V
---
K
K
T
-
A
E
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.64
27%
10
- C3 -
4LX0
-
MYO5B_HUMAN
B:
[170-249]
--------------------------------------------------------------------------------------------------------------------------------------
R
Q
------
V
L
S
-
D
L
S
I
Q
-------------------------------
I
Y
----------
Q
Q
L
I
K
I
-
A
-
E
G
---
V
L
Q
---
P
M
I
V
----
S
A
M
L
E
-
N
---
E
S
I
Q
G
L
S
---------------------
N
S
Y
C
L
E
A
I
I
R
------
Q
M
N
A
F
H
T
V
M
C
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
53.14
13%
-5
- C3 -
2PB9
-
?
A:
[4-186]
--------------------------------------------------------------------------------------E
K
W
R
I
Y
E
E
L
T
N
A
V
R
E
F
E
S
I
N
P
V
R
L
I
P
E
V
G
T
N
F
V
Y
S
L
P
L
P
Y
A
R
S
----
T
K
D
------
V
A
G
V
K
G
R
I
V
K
Y
G
N
S
V
K
A
----
V
G
P
V
E
F
G
A
S
D
--------
H
L
A
----------
R
A
V
L
T
Y
M
R
-
F
Y
---
P
E
Y
---
R
S
A
I
N
I
R
Y
S
R
E
I
I
-
E
-
E
I
I
E
I
A
Q
E
R
G
F
-
K
V
S
F
Y
D
R
R
E
E
P
E
E
-
I
K
A
K
E
G
A
T
I
P
W
G
I
E
------
T
A
I
K
R
I
K
E
R
P
D
I
-----
I
Y
H
L
G
-
D
V
G
---
K
E
P
M
I
L
V
F
G
R
N
P
R
E
V
L
E
K
I
K
M
L
I--------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
52.26
28%
-50
- C3 -
2F4M
-
B:
[13-56]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
----
M
R
Q
I
I
Q
Q
N
P
S
--------
L
L
P
----------
A
L
L
Q
Q
I
-
G
R
E
N
---
P
Q
-------
L
----
L
Q
Q
I
S
-
Q
-
H
Q
E
H
F
I
Q
M
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
Fugue
48.21
9%
-18
- C3 -
2FBY
-
WRN_HUMAN
A:
[5-200]
------------------------------------------------------------------------------------------HHSVFEDD
L
P
F
L
E
F
T
G
S
I
V
Y
S
Y
D
A
-----
S
D
C
S
F
L
S
E
D
I
----
S
M
S
L
SDG
D
V
V
G
F
-
D
M
E
W
P
P
L
Y
N
R
G
K
L
GKVA
L
I
Q
L
C
V
S
E
S
K
--------
C
Y
L
F
HVSSMSVFP
Q
G
L
K
M
L
-
L
-
E
N
---
K
A
V
---
K
K
A
G
----
V
G
-
I
E
-
G
-
D
Q
W
K
L
L
R
D
F
D
I
-
K
L
K
N
F
V
E
L
T
-
D
V
A
-
N
K
K
L
K
C
T
---
E
T
W
S
------
L
N
S
L
V
K
H
L
L
G
K
Q
-----
L
L
K
D
K
-
S
I
R
---
C
S
N
-
W
S
K
F
P
L
T
E
D
Q
K
L
Y
A
A
T
D
A
Y
A
G
F
I
I
Y
R
N
L
E
I
LD-------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
46.83
11%
-51
- C3 -
2QSB
-
Y600_THEAC
A:
[17-88]
-------------------------------------------------------------------------------------------------------------------------------
Y
L
----
L
D
E
------
L
S
Q
-
D
I
T
V
P
K
N
V
R
K
V
A
Q
----
D
S
K
A
K
L
S
Q
E
N
ES
L
D
L
R
C
A
T
V
L
----------
S
M
L
D
E
M
-
A
-
N
D
---
P
N
V
P
A
H
G
R
T
D
----
L
Y
T
I
I
-
S
-
K
L
E
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
45.39
29%
-36
- C3 -
1PVE
-
A:
[16-57]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
----
M
R
Q
I
I
Q
Q
N
P
S
--------
L
L
P
----------
A
L
L
Q
Q
I
-
G
R
E
N
---
P
Q
-------
L
----
L
Q
Q
I
S
-
Q
-
H
Q
E
H
F
I
Q
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
44.61
23%
-48
- C3 -
2RHF
-
?
A:
[32-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
T
----
L
E
A
L
A
-
A
R
Q
P
R
T
L
A
E
L
A
E
V
-
P
--
G
L
G
----
E
K
R
-
I
E
A
Y
G
E
R
I
L
D
A
I
N
T
------
V
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
38.63
9%
45
- C3 -
3D1K
2
HBA1_TRENE
A:
[22-89]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
---
G
N
D
A
----
L
S
R
M
I
V
V
-
Y
P
Q
T
K
I
Y
F
S
H
W
-
P
D
V
T
P
G
S
P
N
I
K
A
H
-
G
K
K
V
M
G
G
I
A
L
A
V
S
K
------
I
D
D
-
L
K
T
G
L
M
E
L
-----
S
E
Q
H
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
35.09
14%
-13
- C3 -
2LNM
-
A:
[6-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
M
E
N
P
D
--------
V
A
M
---------------
A
-
F
-
Q
N
---
P
R
V
---
Q
A
A
L
-----
M
E
C
S
-
E
-
N
P
M
N
I
M
K
Y
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
34.06
11%
25
- C3 -
2OEE
-
YHEA_BACSU
A:
[70-112]
-----------------------------------------------------------------------------------------------------------------------------
A
Q
K
T
----
V
A
L
------
V
Q
Q
-
H
E
K
I
S
Q
L
M
E
A
E
Q
R
----
M
S
M
L
I
G
E
L
N
K
--------
I
I
M
----------
K
P
L
E
E
L
-
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
33.80
30%
102
- C3 -
2QSF
-
RAD23_YEAST
X:
[261-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
L
S
----
L
R
Q
V
V
S
G
N
P
E
--------
A
L
A
----------
P
L
L
E
N
I
-
S
A
R
Y
---
P
Q
-------
L
----
R
E
H
I
M
-
A
-
N
P
E
V
F
V
S
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
33.45
15%
-23
- C3 -
2LLW
-
STI1_YEAST
A:
[523-562]
-------------------------------------------------------------------------------------------------------------------------
S
N
E
T
P
E
E
T
----
Y
Q
R
------
A
M
K
-
D
P
E
V
A
A
---------------
I
M
Q
D
P
V
--------
M
Q
-----------
S
I
L
Q
Q
A
-
Q
-
Q
N
---
P
A
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
31.43
13%
21
- C3 -
2LNZ
-
MDY2_YEAST
A:
[175-206]
-----------------------------------------------------------------------------------------------------------------------------------------------------
L
T
V
P
W
D
D
I
E
A
----
L
L
K
N
N
F
E
N
D
Q
--------
A
A
V
R
---------
Q
V
M
E
R
L
-
Q
-
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
29.44
14%
33
- C3 -
3VEJ
-
MDY2_YEAST
A:
[7-35]
--------------------------------------------------------------------------------------------------------------------------------------------------------
P
W
D
D
I
E
A
----
L
L
K
N
N
F
E
N
D
Q
--------
A
A
V
R
---------
Q
V
M
E
R
L
-
Q
-
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
User Run . : Multi Template Modeling Result:
(2 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAHHHHHHFI
S
P
Q
K
I
V
PL
S
Y
N
E
F
I
R
K
V
V
SDH
S
I
Q
E
Q
E
K
E
I
R
R
L
S
Q
I
VFG
N
Q
N
Q
L
A
N
Q
L
S
Q
I
HENP
S
F
T
K
I
I
S
N
TLTN
S
P
E
S
F
A
K
LAGSKTFGIKN
S
K
R
K
Q
A
E
K
N
I
S
K
L
V
E
A
I
H
K
Y
A
D
A
V
E
N
S
M
G
N
I
I
KNH
N
A
E
Q
K
R
L
A
Q
SVELPSD
48
78.21
100%
-24
- C- -
M048
-
A:
[1-152]
M
A
H
H
H
H
H
H
F
I
S
P
Q
K
I
V
P
L
S
Y
N
E
F
I
R
K
V
V
S
D
H
S
I
Q
E
Q
E
K
E
I
R
R
L
S
Q
I
V
F
G
N
Q
N
Q
L
A
N
Q
L
S
Q
I
H
E
N
P
S
F
T
K
I
I
S
N
T
L
T
N
S
P
E
S
F
A
K
L
A
G
S
K
T
F
G
I
K
N
S
K
R
K
Q
A
E
K
N
I
S
K
L
V
E
A
I
H
K
Y
A
D
A
V
E
N
S
M
G
N
I
I
K
N
H
N
A
E
Q
K
R
L
A
Q
S
V
E
L
P
S
D
42
78.21
100%
-24
- C- -
M042
-
A:
[1-152]
M
A
H
H
H
H
H
H
F
I
S
P
Q
K
I
V
P
L
S
Y
N
E
F
I
R
K
V
V
S
D
H
S
I
Q
E
Q
E
K
E
I
R
R
L
S
Q
I
V
F
G
N
Q
N
Q
L
A
N
Q
L
S
Q
I
H
E
N
P
S
F
T
K
I
I
S
N
T
L
T
N
S
P
E
S
F
A
K
L
A
G
S
K
T
F
G
I
K
N
S
K
R
K
Q
A
E
K
N
I
S
K
L
V
E
A
I
H
K
Y
A
D
A
V
E
N
S
M
G
N
I
I
K
N
H
N
A
E
Q
K
R
L
A
Q
S
V
E
L
P
S
D