@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S39A1_HUMAN: (2015-12-10 )
MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHEGSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLLFIQI
Atome Classification :
(20 SA)
---.........10...----.....20.......-----.30........40-.........50........60..-----------......70--........--.80........90........100.......110..---.....-120.......130.......------140.......150.......160.--......170.......180.......190..---------------------------.....200.......210.......220...-----....230.......240----------------------.......250.......260.......270.......280.......290.......300.......310.......320..-------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MGPWGEP
E
L
L
V
WRP----EAVASEPPVP
V
G
L
E
-----
V
K
L
G
A
L
V
L
L
L
V
L
--
T
L
L
C
S
L
V
P
I
C
VLRRPGANHEG
S
A
-----------
S
R
Q
K
A
L
S
---
L
V
S
C
FA
G
G
--
V
F
L
A
T
C
L
L
D
L
L
P
D
Y
L
A
A
I
D
E
A
L
A
A
L
H
V
T
L
QF
P
L
Q
E
F
---
I
L
A
M
G
-
F
F
L
V
L
V
M
E
Q
I
T
L
A
Y
KEQSGP------S
P
L
E
E
T
R
A
L
L
GTVNGGPQHWHDGP--GVPQASGAPA
T
P
S
A
L
R
A
C
V
L
V
F
S
L
A
L
H
S
V
F
E
---------------------------
G
L
A
V
G
L
Q
R
D
R
A
R
A
M
E
L
C
L
A
L
L
L
HK
G
I
L
A
V
S
L
-----
S
L
R
L
L
Q
S
H
L
R
A
Q
V
V
A
G
C
----------------------
G
I
L
F
S
C
M
T
P
L
G
I
G
L
G
A
A
L
A
ESAG
P
L
H
Q
L
A
Q
S
V
L
E
G
MAAG
T
F
L
Y
I
T
F
L
E
I
L
P
Q
E
L
A
S
S
E
Q
R
I
L
K
V
I
L
L
L
A
G
F
A
L
L
T
G
L
L
F
I
QI-------------------------------------
34
Fugue
78.80
16%
-123
- C5 -
2OCC
-
COX3_BOVIN
C:
[1-261]
---
M
T
H
---------
Q
T
----
H
A
Y
H
M
V
N
P
S
P
W
P
L
T
-----
G
A
L
S
A
L
L
M
T
S
G
L
--
T
M
W
F
H
F
--------------
N
S
M
-----------
T
L
L
M
I
G
L
---
T
T
N
M
L
T
M
Y
--
Q
W
W
R
D
V
I
R
E
S
T
F
Q
G
H
H
T
P
A
V
Q
K
G
L
R
Y
G
M
I
L
F
I
I
S
E
V
---
L
F
F
T
G
-
F
F
W
A
F
Y
H
S
S
L
A
--------
P
------
T
P
E
L
----------
G
G
C
W
P
P
T
G
I
H
--
P
L
N
P
L
E
V
P
L
L
N
T
S
V
L
L
A
S
G
V
S
I
T
W
A
H
H
S
L
M
E
---------------------------
G
-------
D
R
K
H
M
L
Q
A
L
F
I
T
I
T
L
G
V
Y
F
T
L
L
Q
-----
A
S
E
Y
Y
E
A
P
F
--------------------------------------
T
I
S
D
G
V
Y
G
S
T
F
F
V
A
T
G
F
H
G
L
H
V
-----
I
I
G
S
T
F
L
I
V
C
F
F
R
Q
L
K
F
H
F
T
S
N
H
H
F
G
F
E
A
G
A
W
Y
W
H
F
V
D
V
V
W
L
F
L
Y
V
S
IYWWGS-------------------------------
39
Fugue
75.14
18%
-89
- C5 -
4MT0
-
?
A:
[1-445]
CTM
I
P
Q
Y
E
Q
P
K
V
E
V
A
E
T
FQND
T
S
V
S
S
I
R
A
V
D
L
G
W
H
D
Y
F
AD
P
R
L
Q
K
L
I
D
I
A
L
E
RN
T
S
L
R
T
A
V
L
N
S
E
I
Y
R
K
Q
Y
M
I
E
R
N
N
L
L
P
T
L
A
A
N
A
N
G
S
R
Q
G
S
L
S
G
G
N
V
S
S
S
Y
N
V
G
--
L
G
A
A
S
Y
E
L
D
L
F
G
R
V
R
S
S
S
E
A
A
L
Q
G
Y
F
A
S
V
A
N
R
D
A
A
H
---
L
S
L
I
A
-
T
V
A
K
A
Y
F
N
E
R
Y
A
E
E
A
M
S
L
A
Q
------
R
V
L
K
T
R
E
E
T
Y
N
A
V
R
I
A
V
Q
G
R
R
D
F
R
RR
P
A
P
A
E
A
L
I
E
S
A
K
A
D
Y
A
H
A
A
R
S
R
E
Q
A
R
N
A
L
A
T
L
I
NRPIPEDLPAGLPLDKQFFV
E
K
L
P
A
G
L
S
S
E
V
L
L
D
R
P
D
I
R
A
A
E
H
A
L
K
Q
A
N
A
N
I
G
A
A
R
A
A
F
F
P
S
I
R
L
T
G
S
V
G
T
G
S
V
E
L
G
G
LFKSGT
G
V
W
A
F
A
P
S
I
T
L
P
IFTW
G
T
N
K
A
N
L
D
V
A
K
L
R
Q
Q
A
Q
I
V
A
Y
E
S
A
V
Q
S
A
F
Q
D
V
A
N
A
L
A
A
R
E
Q
L
D
K
A
Y
D
A
L
S
K
Q
S
R
A
S
K
E
A
L
R
L
V
G
L
R
Y
K
H
G
V
S
G
A
L
D
L
L
D
A
E
R
S
S
Y
S
A
E
G
A
A
L
S
A
Q
L
T
R
A
E
N
L
A
D
L
Y
K
A
L
GGGLKRDTQT
4
PsiBlast_PDB
63.09
29%
-93
- C6 -
4CET
2
NQO1_HUMAN
A:
[101-171]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
S
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
61.53
29%
-115
- C6 -
1KBQ
2
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
5
PsiBlast_PDB
61.48
29%
-120
- C6 -
4CF6
4
NQO1_HUMAN
A:
[101-171]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
S
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
------------------------------------------------------------------------------------
7
PsiBlast_PDB
60.71
29%
-112
- C6 -
1DXO
4
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
9
PsiBlast_PDB
60.68
29%
-106
- C6 -
1KBO
2
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
15
PsiBlast_PDB
60.65
29%
-113
- C6 -
1H69
2
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
11
PsiBlast_PDB
60.40
29%
-114
- C6 -
2F1O
3
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
14
PsiBlast_PDB
60.13
29%
-110
- C6 -
1H66
2
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
12
PsiBlast_PDB
60.08
29%
-104
- C6 -
3JSX
3
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
-------------------------------------------------------------------------------------
6
PsiBlast_PDB
59.80
29%
-104
- C6 -
1D4A
2
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
8
PsiBlast_PDB
59.75
29%
-109
- C6 -
1GG5
2
NQO1_HUMAN
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
13
PsiBlast_PDB
59.04
29%
-105
- C6 -
1QBG
2
NQO1_HUMAN
A:
[79-149]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
A
M
Y
D
K
------
G
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
I
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
Q
L
T
---------------------------
Y
S
I
G
H
T
P
A
D
A
R
I
Q
I
L
E
G
W
K
K
R
L
E
N
I
W
D
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
M
K
K
E
V
Q
D
E
E
K
N
K
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
T
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
16
PsiBlast_PDB
58.17
29%
-104
- C6 -
1DXQ
2
NQO1_MOUSE
A:
[80-150]
---------------------------------------------------------------------------------------------------------------------
L
S
P
D
I
V
A
E
H
K
K
L
E
A
A
D
L
V
I
F
Q
F
P
L
Q
W
F
GVP
A
I
L
K
G
-
W
F
E
R
V
L
V
A
G
F
A
Y
T
Y
A
A
M
Y
D
N
------
G
P
F
Q
N
K
K
T
L
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
--
G
V
H
G
D
M
N
V
I
L
W
P
I
Q
S
G
I
L
R
F
C
G
F
Q
V
L
E
P
Q
L
V
---------------------------
Y
S
I
G
H
T
P
P
D
A
R
M
Q
I
L
E
G
W
K
K
R
L
E
T
V
W
E
E
T
P
L
-----
Y
F
A
P
S
S
L
F
D
L
N
F
Q
A
G
F
L
----------------------
L
M
K
E
V
Q
E
E
Q
K
K
N
K
F
G
L
S
V
G
H
H
L
G
K
S
I
P
A
D
N
Q
I
K
A
R
K
-----------------------------------------------------------------------------------
35
Fugue
57.80
11%
-109
- C5 -
2NXV
1
YAT6_RHOBL
A:
[1-249]
---
M
K
P
V
P
T
Y
V
Q
D
K
D
E
S
----
T
L
M
F
S
V
C
S
L
V
R
D
Q
A
-----
K
Y
D
R
L
L
E
S
F
E
R
F
--
G
F
T
P
D
K
A
E
F
L
A
A
D
N
R
E
-
G
N
Q
F
H
G
-----------
F
S
W
H
K
Q
M
---
L
P
R
C
K
G
R
Y
--
V
I
F
C
H
E
D
V
E
L
V
D
R
G
Y
D
D
L
V
A
A
I
E
A
L
E
E
A
D
P
-----------
K
W
L
-
V
A
G
V
A
G
S
P
W
--------
R
P
L
------
N
H
S
V
T
A
Q
A
L
H
I
S
D
V
F
G
N
D
R
R
R
----------
G
N
V
P
C
R
V
E
S
L
D
E
C
F
L
L
M
R
R
L
K
P
V
L
N
S
---------------------------
Y
D
M
Q
G
F
H
------------------
Y
Y
G
A
D
L
-----
C
L
Q
A
E
F
L
G
G
R
A
Y
A
I
---------------------------------------------
D
F
H
L
H
H
Y
G
R
A
I
---
A
D
E
N
F
H
R
L
R
Q
E
M
A
Q
K
Y
R
R
W
F
P
G
R
I
L
H
C
V
T
G
R
V
A
L
G
G
G
W
Y
E
A
R
-------------------------------------------
37
Fugue
52.52
10%
-70
- C5 -
3CEQ
-
KLC2_HUMAN
B:
[211-479]
---
L
V
P
R
G
S
A
V
P
L
C
K
Q
A
----
L
E
D
L
E
K
T
S
G
H
D
H
P
D
-----
V
A
T
M
L
N
I
L
A
L
V
Y
--
R
D
------------
Q
N
K
Y
K
E
A
A
H
-----------
L
L
N
D
A
L
A
---
I
R
E
K
T
L
G
K
DH
P
A
V
A
A
T
L
N
N
L
A
V
L
Y
G
K
R
G
K
Y
K
E
A
E
P
L
C
K
R
A
L
E
I
R
E
K
---
V
L
G
K
F
H
P
D
V
A
K
Q
L
S
N
L
A
L
L
C
Q
N
Q
G
K
A
------
E
E
V
E
Y
Y
Y
R
R
A
L
E
I
Y
A
T
R
L
------------
G
P
D
D
P
N
V
A
K
T
K
N
N
L
A
S
C
Y
L
K
Q
---------------------------------
G
K
Y
Q
D
A
E
T
L
Y
K
E
I
L
T
R
A
H
E
K
E
F
G
S
V
N
G
D
N
K
P
-----
I
W
M
H
A
E
E
R
E
E
S
K
D
K
R
R
------------------------------
D
S
A
P
Y
G
E
Y
G
S
W
Y
K
A
C
K
V
D
S
P
T
V
N
T
T
L
R
S
L
G
A
L
Y
R
R
Q
G
K
L
E
A
A
H
T
L
E
D
C
A
S
R
N
R
-----------------------------------------------------------
18
PsiBlast_PDB
47.22
36%
31
- C6 -
4QWP
-
?
A:
[69-123]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
E
L
V
R
A
Y
S
A
S
S
P
G
------
N
P
L
E
Q
Y
I
P
A
L
E
A
V
N
G
T
D
S
H
A
G
L
G
Q
--
G
F
E
Q
A
W
A
D
A
A
E
T
S
E
F
R
A
A
Q
D
A
E
R
D
R
V
Y
F
D
P
A
---------------------------
V
A
Q
G
K
A
D
G
L
S
A
L
G
Q
F
A
Y
Y
D
T
L
V
V
H
G
P
G
S
Q
R
D
-----
A
F
G
G
I
R
A
E
A
L
S
A
A
L
P
P
S
----------------------
Q
G
G
D
E
T
E
Y
L
E
A
F
F
D
A
R
N
V
I
M
R
E
E
P
A
H
A
D
T
S
R
I
D
T
A
Q
R
V
F
L
Q
N
G
N
F
D
L
E
R
P
L
T
W
S
V
Y
G
D
Q
Y
S
L
N
--------------------------------------------------------
17
PsiBlast_PDB
46.39
36%
32
- C6 -
4OLT
1
?
A:
[69-123]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
E
L
V
R
A
Y
S
A
S
S
P
G
------
N
P
L
E
Q
Y
I
P
A
L
E
A
V
N
G
T
D
S
H
A
G
L
G
Q
--
G
F
E
Q
A
W
A
D
A
A
E
T
S
E
F
R
A
A
Q
D
A
E
R
D
R
V
Y
F
D
P
A
---------------------------
V
A
Q
G
K
A
D
G
L
S
A
L
G
Q
F
A
Y
Y
D
T
L
V
V
H
G
P
G
S
Q
R
D
-----
A
F
G
G
I
R
A
E
A
L
S
A
A
L
P
P
S
----------------------
Q
G
G
D
E
T
E
Y
L
E
A
F
F
D
A
R
N
V
I
M
R
E
E
P
A
H
A
D
T
S
R
I
D
T
A
Q
R
V
F
L
Q
N
G
N
F
D
L
E
R
P
L
T
W
S
V
Y
G
D
Q
Y
S
L
N
--------------------------------------------------------
2
PsiBlast_PDB
46.05
31%
-34
- C7 -
1IA5
-
PGLR1_ASPAC
A:
[49-122]
------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
F
S
G
E
T
T
F
G
Y
K
E
W
S
G
P
L
I
S
V
S
G
S
D
L
T
I
T
G
A
S
G
H
S
I
N
G
D
G
S
R
W
W
D
G
E
--
G
---
G
N
G
G
K
T
K
P
K
F
F
A
A
H
S
L
T
-----
N
S
V
I
S
---------------------------
G
L
K
I
V
N
S
P
V
Q
V
F
S
V
A
G
S
D
Y
L
T
L
K
D
I
T
I
D
N
S
D
-----
G
D
D
N
G
G
H
N
T
D
A
F
D
I
G
T
S
----------------------
T
Y
V
T
I
S
G
A
T
V
Y
N
Q
D
D
C
V
A
V
N
S
G
E
N
I
Y
F
S
G
G
Y
C
S
G
G
H
G
L
S
I
G
S
V
G
G
R
S
D
N
T
V
K
N
V
T
F
V
D
S
T
I
I
N
S
D
N
G
V
R
I
K
T
N
I
D
T
T
G
S
V
S
D
-------------------------------------