@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S39A3_HUMAN: (2015-12-10 )
MVKLLVAKILCMVGVFFFMLLGSLLPVKIIETDFEKAHRSKKILSLCNTFGGGVFLATCFNALLPAVREKLQKVLSLGHISTDYPLAETILLLGFFMTVFLEQLILTFRKEKPSFIDLETFNAGSDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQGLSRASPVRLLSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMARSAMPLRDAAKLAVTVSAMIPLGIGLGLGIESAQGVPGSVASVLLQGLAGGTFLFITFLEILAKELEEKSDRLLKVLFLVLGYTVLAGMVFLKW
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130----.-........140.------......150.......160.......170...----....180.......190..----....--.200.--......210---.......220.......230.......240.......250-.....--...260.......270.......280--------------------.......290.......300...--....310..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
V
K
L
L
V
A
K
I
L
C
M
V
G
V
F
F
F
M
L
L
GSLL
P
V
K
I
IE
T
D
F
E
K
A
H
R
S
K
K
I
L
S
L
C
N
T
FGG
G
V
F
L
A
T
C
F
N
A
L
L
P
A
V
R
E
K
L
Q
K
V
L
SLGHISTDY
P
L
A
E
T
I
L
L
L
G
F
F
M
T
V
F
L
E
Q
L
I
L
T
F
RKEKP
S
F
I
D
L
E
TFNAGSDVGSD------S-EYESPFMGGARG------
H
A
L
Y
V
EPHGHGPS
L
S
V
QGLSRAS
P
V
R
L
L
S
L
A
F
----
A
L
S
A
H
S
V
F
E
G
L
A
L
G
L
Q
EE
G
----
E
K
V
V
--
S
L
F
V
G
--
V
A
V
H
E
T
L
V
A
---
V
A
L
G
I
S
M
A
RSAMP
L
R
D
A
A
K
L
A
V
T
V
S
A
M
I
P
L
G
I
GLGLGIE--SAQGV--
P
G
S
V
A
S
V
L
L
Q
GLAGGT
F
L
F
I
T
F
L
E
I
L
--------------------
A
K
E
L
E
E
K
S
D
R
L
L
K
V
L
F
L
V
L
G
Y
T
V
--
L
A
G
M
V
FLKW
35
Fugue
81.74
17%
-98
* C4 *
3RFA
1
RLMN_ECOLI
A:
[17-349]
K
I
N
L
L
D
L
N
R
Q
Q
M
R
E
F
F
K
D
L
G
--------------
E
K
P
F
R
A
D
Q
V
M
K
W
M
Y
H
Y
C
C
D
N
F
D
E
--
M
T
D
I
N
K
V
L
R
G
K
L
K
E
V
A
E
I
R
A
P
E
V
V
E
E
Q
R
S
S
D
G
T
I
K
W
A
I
A
V
G
D
Q
R
V
E
T
V
Y
I
P
E
D
D
R
----
A
T
L
C
V
S
S
Q
V
G
C
A
LECKFC
S
-
T
A
Q
Q
G
F
N
R
N
L
R
V
------
S
E
I
I
G
Q
V
W
R
A
A
K
I
V
G
A
A
K
V
T
G
Q
R
P
I
T
N
V
V
M
M
G
MGEP
L
L
N
L
N
N
V
V
P
A
M
E
I
M
L
D
D
F
G
FGLS
K
R
R
V
--
T
L
S
T
S
GV
V
P
A
L
D
K
L
G
D
M
I
D
V
A
L
A
I
S
L
H
A
P
N
D
E
I
R
D
E
I
V
P
I
N
K
K
Y
N
I
E
T
F
L
A
A
V
R
R
Y
L
E
K
S
N
A
N
Q
G
--
R
V
T
I
E
Y
V
M
L
D
H
V
N
D
G
T
E
H
A
H
Q
L
A
E
L
L
K
D
T
P
C
K
I
N
L
I
P
W
N
P
F
P
GAPY
G
R
S
S
N
S
R
I
D
R
F
S
K
V
L
M
S
-
Y
G
F
T
T
--
I
V
R
K
T
R
G
D
-
38
Fugue
77.48
14%
-113
- C2 -
3DKT
1
MARIT_THEMA
A:
[1-264]
M
E
F
L
K
R
S
F
A
P
-------
L
T
E
K
Q
W
Q
E
I
D
N
R
A
R
E
I
F
K
T
Q
L
Y
G
R
K
F
V
D
V
E
G
P
Y
G
W
E
----------
Y
A
A
H
P
L
G
E
V
E
V
L
S
D
E
N
E
V
V
K
W
G
L
R
K
S
L
P
L
I
E
L
R
A
T
F
T
L
D
L
W
E
L
D
N
L
E
R
G
K
P
N
V
D
L
S
S
L
E
E
T
V
R
K
V
A
E
------
F
-
E
D
E
V
I
F
R
G
C
--------------------
E
K
S
G
V
K
G
L
L
S
F
E
E
R
K
I
E
C
G
S
T
----
P
K
D
L
L
E
A
I
V
R
A
L
S
I
F
S
K
D
G
I---
E
G
P
Y
--
T
L
V
I
N
--
T
D
R
W
I
N
F
L
K
---
E
E
A
G
------
H
Y
P
L
E
K
R
V
E
E
C
L
R
G
G
K
I
I
T
T
P
-------------------
R
I
E
D
A
L
V
V
S
E
R
G
G
D
F
K
L
I
L
G
Q
D
L
S
--------------------
I
G
Y
E
D
R
E
K
D
A
V
R
L
F
I
T
E
T
F
T
F
Q
V
VN
P
E
A
L
I
L
L
K
-
36
Fugue
57.49
9%
-63
- C4 -
2QV6
2
GCH3_METJA
A:
[1-253]
M
I
Q
I
T
V
I
Q
I
D
N
-----
Y
G
P
W
T
V
T
P
N
P
R
R
E
S
D
L
Q
A
L
Q
S
R
L
Y
A
D
L
N
L
M
F
G
A
H
K
G
L
V
F
Y
T
R
--
F
D
N
L
I
A
I
T
N
G
I
D
L
I
T
H
K
R
I
Q
E
S
I
R
N
R
Y
P
F
T
V
S
M
V
I
A
S
A
E
T
P
Y
E
A
Q
K
L
A
T
E
T
L
Q
E
Y
G
S
A
Q
D
------
E
N
R
K
------
E
-
V
L
D
V
A
N
E
L
V
V
D
G
------
Y
V
Q
I
A
H
I
D
I
-------
N
N
I
T
G
T
L
T
D
I
V
S
A
Y
D
T
----
Y
L
N
V
N
K
V
K
L
A
L
M
E
E
L
L
K
Y
N
----
A
L
L
F
--
F
I
-------
G
G
D
N
F
M
A
---
P
S
-------
N
G
M
S
E
E
D
F
L
D
I
F
N
R
I
N
K
K
Y
K
I
E
L
K
A
G
I
G
I
G
--
R
T
A
E
D
--
A
S
N
L
A
D
I
G
L
E
K
I
R
G
K
L
---------
V
--------------------
D
K
N
V
C
T
L
K
Q
D
D
F
----------------------
29
Fugue
55.11
13%
-90
- C1 -
2ONK
-
WTPB_ARCFU
C:
[24-275]
-
M
R
L
L
F
S
A
L
L
A
L
L
S
S
I
I
L
L
F
V
L
L
P
V
A
A
T
V
T
L
Q
L
F
N
F
D
E
F
L
K
A
A
S
D
-------------------
P
A
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
-----
R
K
S
F
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
I
-------------------
P
H
T
V
A
G
I
A
L
------
L
V
V
F
G
S
S
G
L
I
G
S
F
S
P
L
K
--
F
V
D
A
L
P
G
I
V
V
A
M
L
----
F
V
S
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
-------------------
V
D
V
R
L
E
H
V
A
---
R
T
L
G
S
S
P
L
R
V
F
F
T
V
-------
S
L
P
L
S
V
R
H
I
V
A
G
A
I
M
S
W
A
--
R
G
I
S
E
--
F
G
A
V
V
V
I
-----
A
Y
Y
P
M
I
A
P
T
L
I
Y
E
R
--------------------
Y
L
S
E
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
V
--
F
V
A
L
R
I
I
V
G
12
PsiBlast_PDB
49.20
29%
-8
- C3 -
2D4V
2
?
A:
[298-391]
---------------------------------------------------------------------------------------------------
F
L
Q
Q
I
L
L
--
R
P
E
D
Y
S
V
V
--
A
T
L
N
L
N
G
D
Y
V
S
D
------
A
L
A
A
E
V
G
G
I
G
M
A
P
G
A
N
L
S
DT
H
A
I
F
E
A
T
H
G
T
A
P
D
I
A
G
Q
G
--
K
A
N
P
S
S
L
I
L
S
A
V
----
M
M
L
E
H
-------
L
G
W
G
E
A
A
----
Q
A
I
V
--
A
A
M
N
A
--
T
I
A
A
G
E
V
T
G
---
D
L
A
A
L
R
G
D
V
P
A
L
S
T
T
E
F
T
A
A
L
I
R
R
F
-------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
48.85
30%
-206
- C3 -
4ZYR
2
?
A:
[79-132]
----
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
----------------
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
G
W
A
L
C
A
S
I
V
G
I
M
F
T
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
------
T
-
D
A
F
S
L
K
L
A
L
E
L
F
------
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
----
F
F
A
T
G
E
Q
G
T
R
V
F
W
Y
V
T
T
M
G
----
E
L
L
N
--
A
S
I
M
F
--
F
A
P
L
I
I
N
R
I
---
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
T
S
A
L
E
V
V
I
L
K
T
L
H
M
F
E
--
V
P
F
L
L
--
V
G
C
F
K
Y
I
T
S
Q
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
--------------------
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
S
I
G
F
Q
--
G
A
Y
L
V
L
G
L
V
9
PsiBlast_PDB
46.08
29%
-71
- C3 -
1IXS
1
RUVB_THET8
B:
[52-108]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
L
A
H
V
I
A
H
E
L
G
V
N
L
R
V
T
--
S
G
P
A
I
EK
P
G
D
L
A
A
I
L
A
N
S
L
E
E
G
D
I
L
F
I
D
E
I
H
R
L
--------------------
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
--
G
P
A
A
R
T
I
R
L
10
PsiBlast_PDB
45.93
29%
-69
- C3 -
1HQC
1
RUVB_THET8
A:
[52-108]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
L
A
H
V
I
A
H
E
L
G
V
N
L
R
V
T
--
S
G
P
A
I
EK
P
G
D
L
A
A
I
L
A
N
S
L
E
E
G
D
I
L
F
I
D
E
I
H
R
L
--------------------
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
--
G
P
A
A
R
T
I
R
L
4
PsiBlast_PDB
45.72
30%
-206
- C3 -
2CFQ
-
LACY_ECOLI
A:
[79-132]
----
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
----------------
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
I
M
F
T
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
------
T
-
D
A
P
S
S
A
T
V
A
N
A
V
------
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
----
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
----
T
G
E
Q
--
G
T
R
V
F
--
G
Y
V
T
T
M
G
E
L
---
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
--
T
S
A
L
E
--
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
--------------------
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
--
F
M
S
V
L
A
G
N
M
2
PsiBlast_PDB
45.71
30%
-203
- C3 -
1PV7
-
LACY_ECOLI
A:
[79-132]
----
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
----------------
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
I
M
F
T
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
------
T
-
D
A
P
S
S
A
T
V
A
N
A
V
------
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
----
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
----
T
G
E
Q
--
G
T
R
V
F
--
G
Y
V
T
T
M
G
E
L
---
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
--
T
S
A
L
E
--
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
--------------------
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
--
F
M
S
V
L
A
G
N
M
1
PsiBlast_PDB
44.54
30%
-197
- C3 -
1PV6
-
LACY_ECOLI
A:
[79-132]
----
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
----------------
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
I
M
F
T
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
------
T
-
D
A
P
S
S
A
T
V
A
N
A
V
------
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
----
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
----
T
G
E
Q
--
G
T
R
V
F
--
G
Y
V
T
T
M
G
E
L
---
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
--
T
S
A
L
E
--
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
--------------------
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
--
F
M
S
V
L
A
G
N
M
20
PsiBlast_PDB
44.51
26%
-65
- C3 -
4OOY
1
AMPC_PSEAE
A:
[13-87]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R
15
PsiBlast_PDB
44.46
26%
-68
- C3 -
4GZB
1
AMPC_PSEAE
A:
[15-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R
18
PsiBlast_PDB
44.29
26%
-67
- C3 -
4HEF
1
AMPC_PSEAE
A:
[13-87]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R
17
PsiBlast_PDB
43.89
26%
-70
- C3 -
3S22
1
AMPC_PSEAE
A:
[15-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R
13
PsiBlast_PDB
43.89
26%
-66
- C3 -
2WZX
1
AMPC_PSEAE
A:
[15-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R
14
PsiBlast_PDB
43.88
26%
-67
- C3 -
2WZZ
1
AMPC_PSEAE
A:
[15-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R
3
PsiBlast_PDB
43.82
30%
-204
- C3 -
2CFP
-
LACY_ECOLI
A:
[79-132]
----
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
----------------
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
I
M
F
T
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
------
T
-
D
A
P
S
S
A
T
V
A
N
A
V
------
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
----
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
----
T
G
E
Q
--
G
T
R
V
F
--
G
Y
V
T
T
M
G
E
L
---
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
--
T
S
A
L
E
--
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
--------------------
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
--
F
M
S
V
L
A
G
N
M
5
PsiBlast_PDB
43.80
30%
-199
- C3 -
2V8N
-
LACY_ECOLI
A:
[79-132]
----
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
----------------
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
G
W
A
L
C
A
S
I
V
G
I
M
F
T
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
------
T
-
D
A
P
S
S
A
T
V
A
N
A
V
------
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
----
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
----
T
G
E
Q
--
G
T
R
V
F
--
G
Y
V
T
T
M
G
E
L
---
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
--
T
S
A
L
E
--
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
--------------------
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
--
F
M
S
V
L
A
G
N
M
16
PsiBlast_PDB
43.64
26%
-59
- C3 -
3S1Y
1
AMPC_PSEAE
A:
[15-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
Q
P
V
M
K
A
N
D
I
P
G
L
A
V
A
I
----
S
L
K
G
E
P
H
Y
F
S
Y
G
L
A
S
K
E
D
G
----
R
R
V
T
PE
T
L
F
E
I
--
G
S
V
S
K
T
F
T
A
---
T
L
A
G
Y
A
L
T
Q
D
K
M
R
L
D
D
R
A
S
Q
H
W
P
A
L
Q
G
S
R
F
D
G
I
S
L
L
D
L
A
--
T
Y
T
A
G
--
G
L
P
L
Q
F
P
D
S
V
Q
K
D
Q
A
Q
I
R
D
Y
Y
R
Q
W
Q
P
--------------------
T
Y
A
P
G
S
Q
R
L
Y
S
N
P
S
I
G
L
F
G
Y
L
A
A
--
R
S
L
G
Q
P
F
E
R