@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : T0844: (2014-07-07 )
MAHHHHHHLIPAEQLPPLKEEEVIEKIENDACIQKSLEKIRALSKLIYNNPEILEQDISHINANPKMGRELSERIINSPKSIGRLKGRKIGYIKSQKYKISEQNAKILSNEIFNYADKVSNIRCTIMREHKAKGRRLLQTVKMPS
Atome Classification :
(20 SA)
---------------------------------------------------------------------........---.10...--------.....---20.----......-------.30........40......-----.-----.50----------------------..-----------------.--.....60--.-..----.....70--.......----..---80....-....-.90.......-----.100........110-.....---..------..120.-......130-----.-.-......140...-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------MAHHHHHH---LI
P
A
E
Q--------LPPL
K
---
E
E
E
----
V
I
E
K
IE-------N
D
A
C
I
Q
K
S
L
E
K
I
R
A
L
S
K
L
I-----Y-----N
N
P
----------------------
E
I
-----------------
L
--
E
Q
D
I
S
HI--N-AN----PKM
G
R
E
---
L
S
E
R
I
IN----S
P
---
K
-
S
I
G
R-LKGR-KI
G
Y
I
KSQ
K
Y
-----KI-SEQN
A
K
I
L
S
N
---
E
I
F
N
Y
---
A
D
------KVS
N
I
R
-
C
T
I
M
R
EHK------A-K-
G
R
R
L
L
Q
T
VKMPS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
82.93
17%
-4
- C4 -
1VK9
1
?
A:
[2-148]
------------------------------------------------------------------GSD
K
I
H
H
H
H
H
H
---
V
--------------
E
K
N
L
---
L
R
S
----
A
L
K
I
F
E
-------
K
-----------
K
D
L
S
L
L
A
-----
Y
-----
S
G
R
----------------------
S
I
-----------------
F
--
E
S
K
D
S
G
L
--
K
-
P
V
----
V
E
L
F
K
R
FDN
L
E
G
S
L
V
I
----
D
K
MVG
K
-
A
A
A
S
-
F
L
L
K
M
K
P
D
H
I
H
A
K
V
I
S
K
P
A
L
K
L
M
N
E
Y
G
Q
S
F
S
Y
D
---
E
K
I
P
F
---
V
L
------
G
K
D
G
K
S
M
C
P
F
E
K
L
V
L
------
E
M
D
D
P
E
E
I
I
R
I
V
L
S
K
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
81.21
26%
-3
- C4 -
3QJJ
-
CAS6L_PYRHO
A:
[1-122]
-------------------------------------------------------------------------
H
H
H
H
---
M
R
I
E
V
K
--------
L
L
P
L
K
---
D
N
P
----
I
L
P
F
N
Y
-------
N
Y
E
V
Y
S
Q
I
L
E
K
V
N
S
I
E
P
T
I
A
K
L
--
L
-----
S
S
P
HGF
W
T
F
S
RIIVR
K
R
K
I
LPDKGI
E
I
-----------------
L
--
S
D
D
V
S
L
Y
I
S
S
-
S
N
----
E
D
I
I
R
A
---
I
A
E
A
V
E
K
----
S
P
---
E
F
K
I
G
E
-
L
S
-
F
-
L
V
G
D
I
K
A
I
K
V
-----
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
77.66
26%
-6
- C4 -
3QJL
-
CAS6L_PYRHO
A:
[4-122]
----------------------------------------------------------------------------
H
---
M
R
I
E
V
K
--------
L
L
P
L
K
---
D
N
P
----
I
L
P
F
N
Y
-------
N
Y
E
V
Y
S
Q
I
L
E
K
V
N
S
I
E
P
T
I
A
K
L
--
L
-----
S
S
P
HGF
W
T
F
S
RIIVR
K
R
K
I
LPDKGI
E
I
-----------------
L
--
S
D
D
V
S
L
Y
I
S
S
-
S
N
----
E
D
I
I
R
A
---
I
A
E
A
V
E
K
----
S
P
---
E
F
K
I
G
E
-
L
S
-
F
-
L
V
G
D
I
K
A
I
K
V
-----
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
64.08
12%
-37
- C4 -
2VT3
1
REX_BACSU
A:
[11-209]
-------------------------------------------------------A
T
A
K
R
L
P
L
Y
Y
R
F
L
K
N
L
H
A
S
G
K
Q
---
R
V
S
S
A
E
--------
L
S
D
A
V
KVD
S
A
T
----
I
R
R
D
F
S
Y
F
GALGY
N
V
D
Y
L
L
S
F
F
R
K
T
L
D
Q
D
D
V
I
-----
L
I
G
VG
N
L
G
T
----------------------
A
F
-----------------
L
--
H
Y
N
T
K
I
S
--
M
-
A
F
D
INE
S
K
I
G
T
E
---
V
G
G
V
P
V
Y
----
N
L
---
D
-
D
L
E
Q
H
V
K
D
E
-
S
V
A
I
L
T
V
P
A
V
-----
A
A
-
Q
S
I
T
D
R
L
V
A
L
GIK
G
I
L
N
F
---
T
P
------
A
R
L
N
V
P
-
E
H
I
R
I
H
H
I
------
D
-
L
-
A
V
E
L
Q
S
L
V
Y
F
L
K
H
YS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
63.34
10%
-4
- C4 -
1UT7
-
NAC19_ARATH
A:
[1-166]
------------------------------------------------------------------GS
H
M
G
I
Q
L
T
Q
L
---
S
L
P
P
G
F
--------
R
F
Y
P
T
---
D
E
E
----
L
M
V
Q
Y
------------
L
C
R
K
A
A
G
Y
D
F
S
L
Q
L
I
-----------
A
E
I
----------------------
D
L
-----------------
Y
--
K
F
D
P
W
V
L
--
P
-
N
K
----
A
L
F
G
E
K
----
E
W
Y
F
F
S
----
P
R
---
D
-
R
P
N
R
-
V
A
G
S
-
G
Y
W
K
A
T
G
T
D
K
-----
I
I
-
S
T
E
G
Q
R
V
G
I
K
---
K
A
L
V
F
---
Y
I
G
KAP
K
G
T
K
T
N
W
I
-
M
H
E
Y
R
L
I
E
------
P
-
S
-
D
D
W
V
L
C
R
I
Y
K
K
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
61.81
24%
7
- C4 -
3QFH
-
?
A:
[18-137]
------------------------------------------------------------------------------------------------------
S
E
E
----
L
Y
Y
S
V
E
Y
K
-----
N
T
A
T
F
N
K
L
V
K
K
-
K
S
L
N
-
V
V
-----
Y
-----
N
I
P
----------------------
E
L
H
V
A
Q
I
K
M
T
K
M
H
A
N
A
L
A
N
Y
--
K
N
D
I
K
Y
I
--
N
-
A
T
--------------
C
S
T
C
I
--------------
D
R
-
T
S
N
E
-
S
L
F
S
R
Q
W
D
M
N
-----
K
I
-
T
N
N
G
A
S
Y
--
D
---
D
L
P
K
H
---
A
N
T
-----
K
I
A
I
I
D
-
T
G
V
M
K
N
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
60.95
23%
10
- C4 -
2PIH
-
YMCA_BACSU
A:
[34-109]
---------------------------------------------------------------------------------------------------------------
A
Q
I
N
-------
E
N
D
K
V
S
T
I
V
N
Q
I
K
A
L
Q
K
Q
A
V
N
L
K
H
Y
-----
E
K
H
----------------------
E
A
-----------------
L
--
K
Q
V
E
A
K
I
--------------
D
A
---
L
Q
E
E
L
E
E
----
I
P
---
V
-
I
----------------
Q
E
F
-----
R
D
-
S
Q
M
E
V
N
D
L
L
Q
---
L
V
A
H
T
---
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
60.06
21%
27
- C4 -
4C3X
7
?
A:
[23-530]
DWTSECD
V
L
V
V
G
SG
G
G
A
L
T
G
A
Y
T
A
A
A
Q
G
L
T
T
I
V
L
E
KTDRFGGTSAYSGASIWLPGT
Q
V
Q
E
R
A
GLPDS
T
E
N
A
R
T
Y
L
R
A
---
L
L
G
D
A
E
-------------------------------------
S
E
R
Q
D
A
Y
V
E
T
A
P
A
V
V
A
L
L
-----
E
-----
Q
N
P
----------------------
N
I
-----------------
E
--
F
E
F
R
A
F
P
--
D
-
Y
Y
----
K
A
E
G
R
M
---
D
T
G
R
S
I
N
P
L
DL
D
P
---
A
-
D
I
G
D
-
L
A
G
K
-
V
R
P
E
L
D
Q
D
R
T
-----
G
Q
-
D
H
A
P
G
P
---------------------------------
M
I
G
G
R
------
A
-
L
-
I
G
R
L
L
A
A
V
Q
S
T
G
K
A
E
L
R
T
E
S
V
L
T
S
L
I
V
E
DGRVV
G
A
E
V
E
S
GG
E
T
Q
R
I
K
A
NR
G
V
L
M
AAGGIEGN
A
E
M
R
E
Q
A
GTPGKAIWSMGPFGANTG
D
A
I
S
A
G
I
A
V
G
G
A
T
A
LLDQAW
F
C
P
G
VEQPDGSAAFMVGVR
G
G
L
V
V
D
SAGERYLNESLP
Y
D
Q
F
G
R
A
M
D
A
H
DDNGSAVP
S
F
M
I
F
D
SREGGGLPAICIPNTA
P
A
K
H
L
E
A
GT
W
V
G
A
DT
L
E
E
L
A
A
K
T
GLP
A
D
A
L
R
S
T
V
E
K
F
N
D
A
A
K
L
GVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGP
F
Y
A
A
R
I
V
LSDLGTKG
G
L
V
T
D
VNG
R
V
L
R
ADGSAIDG
L
Y
A
A
G
NTSASLSGRFYPGPG
V
P
L
G
T
A
M
V
F
S
Y
R
A
A
Q
D
M
A
K
4
PsiBlast_PDB
59.00
24%
-14
- C4 -
3T41
-
?
A:
[43-161]
-------------------------------------------------------------------------------------------------------
E
E
----
L
Y
Y
S
V
E
Y
K
-----
N
T
A
T
F
N
K
L
V
K
K
-
K
S
L
N
-
V
V
-----
Y
-----
N
I
P
----------------------
E
L
H
V
A
Q
I
K
M
T
K
M
H
A
N
A
L
A
N
Y
--
K
N
D
I
K
Y
I
--
N
-
A
T
--------------
C
S
T
C
I
T
----
S
E
---
K
-
T
I
D
R
----
E
-
S
L
F
S
R
Q
W
D
M
N
-----
K
I
-
T
N
N
G
A
S
Y
--
D
---
D
L
P
K
H
---
A
N
T
-----
K
I
A
I
I
D
-
T
G
V
M
K
N
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
55.68
23%
57
- C4 -
3M8E
-
?
A:
[-15-102]
---------------------------------------------------------------------------
F
Y
-------------------
T
L
N
---
I
A
E
----
I
A
E
R
I
G
-------
N
D
D
C
A
Y
Q
V
L
M
A
------
F
I
-----
N
-----
E
N
G
----------------------
E
A
-----------------
Q
--
M
L
N
K
T
A
V
--
A
-
E
M
----
I
Q
L
S
K
P
---
T
V
F
A
T
V
N
----
S
F
---
Y
-
C
A
G
Y
-
I
D
E
T
-
R
V
G
--
R
S
K
I
Y
-----
T
L
-
S
D
L
G
V
E
I
V
E
-----------------------------
C
F
K
Q
K
A
------
M
-
E
-
M
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
53.82
16%
27
- C3 -
1XPN
-
?
A:
[1-170]
--------------------------------------------------------------------G
S
S
H
H
H
H
H
H
SSG
L
V
P
R
G
S
H
MASNPND
L
P
D
F
P
---
E
H
E
----
Y
A
A
T
Q
-------------
Q
V
G
G
G
V
I
N
G
D
L
Y
L
T
-----
S
-----
A
S
G
----------------------
A
I
-----------------
Q
--
K
G
T
N
T
K
V
--
A
-
L
E
----
P
A
T
S
Y
M
---
K
A
Y
Y
A
K
F
----
G
N
---
L
-
D
A
A
K
-
R
D
P
D
-
V
Q
P
P
V
L
D
P
R
R
-----
A
T
-
Y
V
R
E
A
T
T
D
Q
N
---
G
R
F
D
F
D
H
I
P
N
------
G
T
Y
Y
I
S
-
S
E
L
T
W
S
A
Q
S
DG
K
T
I
T
-
E
-
G
G
T
V
T
K
L
V
T
V
S
G
SQP
Q
K
V
L
L
TR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
53.18
20%
-55
- C4 -
1OQY
-
RD23A_HUMAN
A:
[232-282]
--------------------------------------------------------------------------------------------------------------
L
E
F
L
R
-------
D
Q
P
Q
F
Q
-------
N
M
R
Q
V
I
-----
Q
-----
Q
N
P
----------------------
A
L
-----------------
L
--
P
A
L
L
Q
Q
L
--
G
Q
E
N
----
P
Q
-------
L
L
Q
Q
I
S
R
----
H
Q
---
E
-
Q
F
I
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
49.60
23%
-74
- C4 -
2XVC
-
?
A:
[4-59]
------------------------------------------------------------------------
H
H
H
H
H
---
M
I
T
E
R
E
--------
L
L
D
Y
I
---
V
N
N
GGFL
D
I
E
H
F
S
-------
K
V
Y
G
V
--
E
K
Q
E
V
V
K
L
L
E
A
L
-----
K
-----
N
K
G
----------------------
L
I
-----------------
A
--
V
E
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
48.81
22%
-42
- C4 -
1PVE
-
A:
[16-57]
--------------------------------------------------------------------------------------------------------------------------------------
Q
Q
M
R
Q
I
I
-----
Q
-----
Q
N
P
----------------------
S
L
-----------------
L
--
P
A
L
L
Q
Q
I
--
G
R
E
N
----
P
Q
-------
L
L
Q
Q
I
S
Q
----
H
Q
---
E
-
H
F
I
Q
-
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
47.58
21%
-46
- C4 -
2F4M
-
B:
[13-55]
-------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
M
R
Q
I
I
-----
Q
-----
Q
N
P
----------------------
S
L
-----------------
L
--
P
A
L
L
Q
Q
I
G
-
R
-
E
N
----
P
Q
-------
L
L
Q
Q
I
S
Q
----
H
Q
---
E
-
H
F
I
Q
-
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.89
23%
-11
* C5 *
3CUP
-
?
B:
[31-86]
------------------------------------------------------------------------------------------------------
E
R
H
----
F
V
H
Q
F
K
-------
G
E
C
Y
F
T
N
G
T
Q
R
I
R
L
V
T
R
Y
I
-----
Y
-----
N
R
E
----------------------
E
Y
-----------------
L
R
F
D
S
D
V
G
E
Y
--
R
-
A
V
----
T
E
L
G
R
H
---
S
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.10
23%
-9
- C5 -
1F3J
1
?
B:
[1-56]
------------------------------------------------------------------------------------------------------
E
R
H
----
F
V
H
Q
F
K
-------
G
E
C
Y
F
T
N
G
T
Q
R
I
R
L
V
T
R
Y
I
-----
Y
-----
N
R
E
----------------------
E
Y
-----------------
L
R
F
D
S
D
V
G
E
Y
--
R
-
A
V
----
T
E
L
G
R
H
---
S
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
43.48
23%
-26
- C5 -
3MBE
-
?
B:
[11-65]
-------------------------------------------------------------------------------------------------------
R
H
----
F
V
H
Q
F
K
-------
G
E
C
Y
F
T
N
G
T
Q
R
I
R
L
V
T
R
Y
I
-----
Y
-----
N
R
E
----------------------
E
Y
-----------------
L
R
F
D
S
D
V
G
E
Y
--
R
-
A
V
----
T
E
L
G
R
H
---
S
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
41.88
35%
-33
- C4 -
1UF9
-
COAE_THET8
A:
[49-83]
--------------------------------------------------------------------------------------------------
K
---
E
E
E
-----
L
K
R
L
F
-------
P
E
A
V
V
G
G
R
L
D
R
-
R
A
L
A
R
L
V
-----
F
-----
S
D
P
----------------------
E
R
-----------------
L
--
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
37.94
13%
34
- C4 -
2OEE
-
YHEA_BACSU
A:
[70-112]
------------------------------------------------------------------------------------------------------
A
Q
K
----
T
V
A
L
V
Q
-------
Q
H
E
K
I
S
Q
L
M
E
A
E
Q
R
M
S
M
L
I
-----
G
-----
E
L
N
----------------------
K
I
-----------------
I
--
M
K
P
L
E
E
L
--
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
User Run . : Multi Template Modeling Result:
(2 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAHHHHHHLI
P
A
E
QLPPL
K
E
E
E
V
I
E
K
IEN
D
A
C
I
Q
K
S
L
E
K
I
R
A
L
S
K
L
IYN
N
P
E
I
L
E
Q
D
I
S
HINANPKM
G
R
E
L
S
E
R
I
INS
P
K
S
I
G
RLKGRKI
G
Y
I
KSQ
K
Y
KISEQN
A
K
I
L
S
N
E
I
F
N
Y
A
D
KVS
N
I
R
C
T
I
M
R
EHKAK
G
R
R
L
L
Q
T
VKMPS
41
77.82
100%
-9
- C- -
M041
-
A:
[1-226]
M
A
H
H
H
H
H
H
L
I
P
A
E
Q
L
P
P
L
K
E
E
E
V
I
E
K
I
E
N
D
A
C
I
Q
K
S
L
E
K
I
R
A
L
S
K
L
I
Y
N
N
P
E
I
L
E
Q
D
I
S
H
I
N
A
N
P
K
M
G
R
E
L
S
E
R
I
I
N
S
P
K
S
I
G
R
L
K
G
R
K
I
G
Y
I
K
S
Q
K
Y
K
I
S
E
Q
N
A
K
I
L
S
N
E
I
F
N
Y
A
D
K
V
S
N
I
R
C
T
I
M
R
E
H
K
A
K
G
R
R
L
L
Q
T
V
K
M
P
S
40
76.26
100%
18
- C- -
M040
-
A:
[1-192]
M
A
H
H
H
H
H
H
L
I
P
A
E
Q
L
P
P
L
K
E
E
E
V
I
E
K
I
E
N
D
A
C
I
Q
K
S
L
E
K
I
R
A
L
S
K
L
I
Y
N
N
P
E
I
L
E
Q
D
I
S
H
I
N
A
N
P
K
M
G
R
E
L
S
E
R
I
I
N
S
P
K
S
I
G
R
L
K
G
R
K
I
G
Y
I
K
S
Q
K
Y
K
I
S
E
Q
N
A
K
I
L
S
N
E
I
F
N
Y
A
D
K
V
S
N
I
R
C
T
I
M
R
E
H
K
A
K
G
R
R
L
L
Q
T
V
K
M
P
S