Atome 2 Filter

Query sequence : MFRN1_HUMAN: (2015-12-08 )
MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY

Atome Classification :

	(20 SA)									-----........-----.10........-20........30.......---.40....-....----------------50.....--...60....------.-...70....-------..----..-80------..--.......90-........100...--..--------..110..--.....120.-----......130.---.----....---------.140.....---..150...-----.--....--160.---..--....170------....-----..-----------.---..180----.........-190--.......-200.....-...210.......-----220--------...----..--.-----..230----....--..----------...-------240--.......250-----------------..--..------...260.------...---...-270....---...280.-......290-....------------------------...300---....--------------....310--.......-------320.......330.------.....-----------------------------------------------------------------------------------------------------
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		-----MELRSGSV-----GSQAVARRMDG-DSRDGGGGKDATGSEDYEN---LPTSASV-STHM----------------TAGAMAG--ILEHSVMYP------V-DSVKTRMQS-------LS----PD-P-------KA--QYTSIYGAL-KKIMRTEGFWRPLR--GV--------NVMIMGA--GPAHAMYFA-----CYENMKRTLN---D----VFHH---------QGNSHLANG---IAG-SMAT-----L--LHDA--VMNP---AE--VVKQR--------LQMY-----NS-----------Q---HRS------AISCIRTVW-RTE--GLGAFYR-S-YTTQLT-MNIPFQSIHFITY-----EF---------LQE----QV--N-----PHR------TYNP--QS----------HII-------SGG--LAGALAAAAT-----------------TP--LD------VCKTLLN------TQE---NVA-LSLANIS---GRLSGMA-NAFRTVYQL-NGLA------------------------GYFKG----IQAR--------------VIYQMPS--TAISWSV-------YEFFKYFLTKRQLE------NRAPY-----------------------------------------------------------------------------------------------------
12	HHSearch	81.61	19%	-45	- C3 -	1OKC		ADT1_BOVIN	A:[4-293]	-------------------------------------------------------ALSF-LKDF----------------LAGGVAA--AISKTAVAP------I-ERVKLLLQV-------QH----AS-KQISA---EK--QYKGIIDCV-VRIPKEQGFLSFWR--GN--------LANVIRY--FPTQALNFA-----FKDKYKQIFL---G----GVDRHKQ------FWRYFAGNL---ASG-GAAG-----A--TSLC--FVYP---LD--FARTR--------LAAD-----VGKGAAQR-----E---FTG------LGNCITKIF-KSD--GLRGLYQ-G-FNVSVQ-GIIIYRAAYFGVY-----DT---------AKG----ML--P-----DPK------NVHI--IV----------SWM-------IAQ--TVTAVAGLVS-----------------YP--FD------TVRRRMM------MQS---GRK-GA----D---IMYTGTV-DCWRKIAKD-EGPK------------------------AFFKG----AWSN--------------VLRGMG---GAFVLVL-------YDEI--------------------------------------------------------------------------------------------------------------------------
21	Fugue	80.73	17%	-46	- C3 -	1OKC		ADT1_BOVIN	A:[2-293]	-----------------------------------------------------DQALSF-LKDF----------------LAGGVAA--AISKTAVAP------I-ERVKLLLQV-------QHASKQIS-A-------EK--QYKGIIDCV-VRIPKEQGFLSFWR--GN--------LANVIRY--FPTQALNFA-----FKDKYKQIFLGGVD----RHKQ---------FWRYFAGNL---ASG-GAAG-----A--TSLC--FVYP---LD--FARTR--------LAAD-----VG-----------K---GAAQREFTGLGNCITKIF-KSD--GLRGLYQ-G-FNVSVQ-GIIIYRAAYFGVY-----DT---------AKG----ML--P-----DPK------NVHI--IV----------SWM-------IAQ--TVTAVAGLVS-----------------YP--FD------TVRRRMM------MQS---GRK-----GAD---IMYTGTV-DCWRKIAKD-EGPK------------------------AFFKG----AWSN--------------VLRGMGG--AFVLVLY-------DEI---------------------------------------------------------------------------------------------------------------------------
29	Fugue	74.96	18%	-47	- C2 -	4RKS		MV3K_THEAC	A:[21-337]	--------TYRSI-----GSTA--YPTIG-VVLLGGIANPVTRT----P---LHTSAGI-AYSD----------------SCGSI-------RSETRI------Y-ADEATHIYF-------NG----TE-S-------TD--DNRSVRRVL-DRY--------------S--------SVFEEAF--GTKTVSYSS-----QNFGILS-------------------------GSSDAGAA---SIG-AAIL-----G--LKPD---LDP---HD--VENDL--------RAVS-----ES-----------A---GRS------LFGGLTITW-SDG-------FH-A-YTEKIL-DPEAFSGYSIVAF-----AFDYQRNPSDVIHQ----NI--VRSDLYPAR------KKHA--DE----------HAHMIKEYAKTND--IKGIFDLAQE-----------------DT--EE------YHSILRG------VGV---NVIRENMQKLI---SYLKLIR-KDYWNAYIV-TG------------------------------G----SNVY--------------VAVESEN--ADRLFSI-------ENTFGS--KKKMLRIVGGAWHRRPE-----------------------------------------------------------------------------------------------------
24	Fugue	71.18	21%	-45	- C2 -	4TQT		?	A:[14-490]	---ASKVIKGGTVITADRTFRADILIEDG-KIAAIGDSLEGDEVIDASGCYVMPGGIDP-HTHLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLL-DALQEWFQK-------AG----K--A-------RT--DYSFHMAIT-GWNERTFNEMAEVVKRGI--------NTFHFMAYKGALMVNDDE-----MFASFQRCAE---LGAMPLVHA---------ENGDIVAQL---QAK-LMAEGNDGPE--AHAY--SRPPEVEGE--ATNRA--------IMIA-----DQAGVPLYV----V---HVS------CEQSHEAIR-RARQKGMRVFGE-P-LIQHLT-LD--ESEYHNRDW-----DY---------AAR----RVMSP-----PFR------DKLN--QD----------SLW-------AGL--AAGSLQCVATDHCAFTTEQKRYGIGNFTK--IP------NGTGGLE------ERM---PVL-WTRGVRT---GRLT--P-NEFVAVTST-NIAKILNIYPQKGAVVPGADADLVIWDPETTKK----ISAKTQHSSIDYNVFEGFELKGLPI--MTLSRGR-------IAFDKGQVTAKPGDGRFI--EREPNGAVNRALSQWKEIVAPRKVERSA------------------------------------------------------------------------------
5	PsiBlast_PDB	64.67	22%	-54	- C3 -	4C9J		ADT3_YEAST	A:[134-290]	--------------------------------------------------------------NL----------------ASGGAAG--ALSLLFVYS------L-DFARTRLAA-------DA----KS-----------ARQFNGLTDVY-KKTLKSDGIAGLYR--GF--------MPSVVGI--VVYRGLYFG-----MFDSLK---------------------------------F---LLG-WVVT-----T--GAST--CSYP---LD--TVRRR--------MMMT-----SG-----------QAVKYNG------AIDCLKKIV-ASE--GVGSLFK-G-CGANIL-RSVAGAGVISMYD-----QL---------QMI----LF--G-----KKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2	PsiBlast_PDB	62.95	23%	-53	- C3 -	4C9H		ADT2_YEAST	A:[130-286]	--------------------------------------------------------------NL----------------ASGGAAG--ALSLLFVYS------L-DYARTRLAA-------DS-----------------ARQFNGLIDVY-KKTLKSDGVAGLYR--GF--------LPSVVGI--VVYRGLYFG-----MYDSLK------------------------------LASF---LLG-WVVT-----T--GAST--CSYP---LD--TVRRR--------MMMT-----SG-----------QAVKYDG------AFDCLRKIV-AAE--GVGSLFK-G-CGANIL-RGVAGAGVISMYD-----QL---------QMI----LF--G-----KKF------K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6	PsiBlast_PDB	62.48	22%	-56	- C3 -	4C9Q		ADT3_YEAST	A:[134-290]	--------------------------------------------------------------NL----------------ASGGAAG--ALSLLFVYS------L-DFARTRLAA-------DA----KS-----------ARQFNGLTDVY-KKTLKSDGIAGLYR--GF--------MPSVVGI--VVYRGLYFG-----MFDSLKPL---------------------------FLASF---LLG-WVVT-----T--GAST--CSYP---LD--TVRRR--------MMMT-----SG-----------QAVKYNG------AIDCLKKIV-ASE--GVGSLFK-G-CGANIL-RSVAGAGVISMYD-----QL---------QMI----LF--G-----K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1	PsiBlast_PDB	61.22	25%	-49	- C3 -	2LCK	-	UCP2_MOUSE	A:[23-298]	-------------------------------------------------------------------------------------AA--CIADLITFP------L-DTAKVRLQIQGESQGLVR----TA-A-------SA--QYRGVLGTI-LTMVRTEG---PRS--LY--------NGLV--A--GLQRQMSFASVRIGLYDSVKQ------------FYT---------KGSEHAGIGSRLLAG-STTG-----A--LAVA--VAQP---TD--VVKVR--------FQAQARAGGGR-----------R---YQS------TVEAYKTIA-REE--GIRGLWK-G-TSPNVA-RNAIVNCAELVTY-----DL---------IKD----TL--L-----KANLM----TDDL--PC----------HFT-------SAF--GAGFCTTVIA-----------------SP--VD------VVKT---------RYM---NSA-L---------GQYHSAG-HCALTMLRK-EGPR------------------------AFYKG----F---------------------MPSFLRLGSWNV-------VMFVTYEQLKRALM------AAYQS-----------------------------------------------------------------------------------------------------
11	HHSearch	61.17	20%	-54	- C3 -	2LCK	-	UCP2_MOUSE	A:[14-304]	------------------------------------------------------------TVKF----------------LGAGTAA--CIADLITFP------L-DTAKVRLQI-------QG----ES-QGLVRTAASA--QYRGVLGTI-LTMVRTEGPRSLYN--GL--------VAGLQRQ--MSFASVRIG-----LYDSVKQFYT---K----GS-----------EHAGIGSRL---LAG-STTG-----A--LAVA--VAQP---TD--VVKVR--------FQAQ-----ARAGGGR------R---YQS------TVEAYKTIA-REE--GIRGLWK-G-TSPNVA-RNAIVNCAELVTY-----DL---------IKD----TL--L-----KANLM----TDDL--PC----------HFT-------SAF--GAGFCTTVIA-----------------SP--VD------VVKTRYM------NSA---LG-------------QYHSAG-HCALTMLRK-EGPR------------------------AFYKG----FMPS--------------FLRLGSW--NVVMFVT-------YEQLKRALMAAYQS------REAPF-----------------------------------------------------------------------------------------------------
23	Fugue	58.85	15%	-6	- C3 -	4PEV		?	A:[52-421]	PISVLVLFDVGGR-----GDLS----FNDMAALGADRAAEELGVDVVFQ---TPQSLAVMESVL----------------DAASRSG----EYDLIVL------VGFLWQEPLEK-------VA----PRYP-------EQ--KYALIDAAT-RE---------RYD--NV--------ASYLFRE--QEVASLVGI-----IAADI---AN---N----ISKA---------TGEEAKAGA---VAGMDIPP-----LWRFHIG--YLYG---VQ--YYNQAMGTDVEMVWTYT-----GR-----------F---DDP------TLGKTTAEQMLQQ--GVRVFYGVA-GLTHVGMFNAVKEAAARGVI-----AF---------SIG----QD--A-----SQE------WYDP--QT----------III-------SGLKRVDVAVYTAIK-----------------DV--VEGRFRGGIVSLGLKEGGLGLSDE---EII-RYFAEIAAETGQLPEGL-TPEKVVEIVMSQRE------------------------KWISN----DGWR--------------LVEELKQ--KIISGEIKFVTPQDHDTYDSIIEELKAG------NLEAALE---------------------------------------------------------------------------------------------------
14	HHSearch	57.21	23%	-46	- C3 -	1OKC		ADT1_BOVIN	A:[5-204]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSFLKDF---LAG-GVAA-----A--ISKT--AVAP---IE--RVKLL--------LQVQ-----HASKQISAEK---Q---YKG------IIDCVVRIP-KEQ--GFLSFWR-G-NLANVI-RYFPTQALNFAFK-----DK---------YKQ----IF--L-----GGVDRHKQFWRYF--AG----------NLA-------SGG--AAGATSLCFV-----------------YP--LD------FARTRLA------ADV---GKG-A----AQ---REFTGLG-NCITKIFKS-DGLR------------------------GLYQG----FNVS--------------VQGIIIY--RAAYFGV-------YDTAKGMLPDPKNV------HIIVS-----------------------------------------------------------------------------------------------------
4	PsiBlast_PDB	56.68	22%	-50	- C3 -	2C3E		ADT1_BOVIN	A:[3-187]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALSFLKDF---LAG-GVAA-----A--ISKT--AVAP---IE--RVKLL--------LQVQ-----HASKQISAEK---Q---YKG------IIDCVVRIP-KEQ--GFLSFWR-G-NLANVI-RYFPTQALNFAFK-----DK---------YKQIFLGGV--D-----RHK------QFWRYFAG----------NLA-------SGG--AAGATSLCFV-----------------YP--LD------FARTRLA------AD--------VGKGAAQ---REFTGLG-NCITKIFKS-DGLR------------------------GLYQGFNVSVQGI--------------IIYRAAY--FGVYDTA-------KGMLPDPKNVHIIV------SWMIA-----------------------------------------------------------------------------------------------------
22	Fugue	55.28	9%	-34	- C2 -	1YA0	-	SMG7_HUMAN	A:[1-497]	-----MSLQSAQY-----LRQAEVLKADM-TDSKLGPAEVWTSRQALQD---LYQKMLV-TDLE----------------YALDKKV--EQDLWNHAF------K-NQITTLQGQ-------AKN---RA-N-------PN--RSEVQANLS-LFLEAASGFYTQLL--QELCTQSSSCSYICQHC--LVHLGDIAR-----YRNQTSQAES---Y----YRHA---------AQLVPSNGQ---PYN-QLAI-----L--ASSKGDHLTT---IF--YYCRS--------IAVK-----FP-----------F---PAA------STNLQKALS-KAL--ESRDEVK-T-KWGVSD-FIKAFIKFHGHVYLSKSLEK---------LSP----LR--E-----KLE------EQFK--EL----------LFQ-------KAF--NSQQLVHVTV-----------------IN--LF------QLHHLRD------FSNETEQHT-YSQDEQL---CWTQLLA-LFMSFLGIL-CKCP------------------------LQNSQ----EESY--------------NAYPLPA--VKVSMDW-------LRLRPRVFQEAVVD------ERQYIWPWLISLLNSFHPHEEDLSISATPLPEEFELQGFLALRPSFRNLDFSKGHKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDP
3	PsiBlast_PDB	55.13	22%	-50	- C3 -	1OKC		ADT1_BOVIN	A:[3-187]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALSFLKDF---LAG-GVAA-----A--ISKT--AVAP---IE--RVKLL--------LQVQ-----HASKQISAEK---Q---YKG------IIDCVVRIP-KEQ--GFLSFWR-G-NLANVI-RYFPTQALNFAFK-----DK---------YKQIFLGGV--D-----RHK------QFWRYFAG----------NLA-------SGG--AAGATSLCFV-----------------YP--LD------FARTRLA------AD--------VGKGAAQ---REFTGLG-NCITKIFKS-DGLR------------------------GLYQGFNVSVQGI--------------IIYRAAY--FGVYDTA-------KGMLPDPKNVHIIV------SWMIA-----------------------------------------------------------------------------------------------------
9	PsiBlast_PDB	54.69	24%	-94	- C3 -	1IG0		THI80_YEAST	A:[123-227]	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTDFT-KCVNLISLHFNSP-----EF---------RSL----IS--N-----KD---------NL--QSNHGIELEKGIHTL-------YNT--MTESLVFSKV-----------------TP--IS------L----------------------LALGGIG---GRFDQTV-HSITQLYTL-SENA------------------------SYFK-----------------------LCYMTPT--DLIFLIK-------KNGTLIEYDPQFRN------TCIGN-----------------------------------------------------------------------------------------------------
13	HHSearch	52.76	24%	-46	- C3 -	2LCK	-	UCP2_MOUSE	A:[15-208]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKF---LGA-GTAA-----C--IADL--ITFP---LD--TAKVR--------LQIQ-----GESQGLVRTAASAQ---YRG------VLGTILTMV-RTE--GPRSLYN-G-LVAGLQ-RQMSFASVRIGLY-----DS---------VKQ----FY--T-----KGSE-----HAGI--GS----------RLL-------AGS--TTGALAVAVA-----------------QP--TD------VVKVRFQ------AQA---RAG-G-----G---RRYQSTV-EAYKTIARE-EGIR------------------------GLWKG----TSPN--------------VARNAIV--NCAELVT-------YDLIKDTLLKANLM------TDDLP-----------------------------------------------------------------------------------------------------
28	Fugue	51.43	8%	-54	* C2 *	2WJ6		HOD_ARTNT	A:[2-275]	---TDTYLHETLV-----FDNKLSYIDNQ-RDTDGP----------AIL---LLPGWCH-DHRV----------------YKYLIQE--LDADFRVIV------P-NW-RGHGLS-------PS----EV-P-------DF--GYQEQVKDA-LEILDQLG----VE--TF--------LPVSHSH--GGWVLVELL-----EQAGPER-------------------------------------AP-RGII-----M--DWLM--WAPK---PD--FAKSL--------TLLK-----------------------------------------DPE--RWREGTH-G-LFDVWL-DGHDEKRVRHHLL-----EE---------MAD----Y------------------------GY----------DCW-------GRS--GRVIEDAYGR-----------------NG--SP------MQMMANL------TKT---RPI-RHIFSQP---TEPEYEK-INSDFAEQH-PWFS------------------------YAKLG----GPTH--------------FPAIDVP--DRAAVHI-------REFATAIRQG--------------------------------------------------------------------------------------------------------------------
30	Fugue	44.11	9%	-62	- C1 -	5AJ3	-	?	G:[35-242]	--------------------------------------------------------------------------------------------------------------SRYGP-------EY----KD-P-------QI--DKEYYRKPLAEQTEEEKYERDFKK--TQ--------LIKAAPA--TKTSSVF--------EDPVISKFT---N----MMMK---------GGNKVLARS---LMT-QTLE-----A--VKRK--QFAK---YHAASAEEQ--------ATIE-----RN-----------P---YTI------FHQALKNCE-PVI--GLVPILK-GGHFYQVP-VPLADRRRRFLAM-----KW---------MIA----EC--R-----EK---------KH--RR----------VLM-------PEK--LSQELLEAFH-----------------NQ--GP------VIKRKHD------MHK---MAE-ANRALAH---YRWW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7	PsiBlast_PDB	43.91	29%	-30	- C3 -	5AHR	-		A:[145-215]	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------C--S-----PEY------TFPS--QQ----------EVI-------RFA--INTAFEAVTL-----------------NPHALV------VCGTYSI------GKE---KVF-LAIADVL---GSKVGMSQEKYKTLQCL-NIPE------------------------INSLI----TTDM--------------CSSLVHL--LPMMQIN-------FKGLQSHLKKCGGK------YNQIL-----------------------------------------------------------------------------------------------------
15	HHSearch	43.00	11%	-60	- C3 -	3F2E		?	A:[8-89]	------------------------------------------------------------------------------------------------------------------------------------------------FTAVAEQV-SAVLSQYGITGPNR--AI--------YQGFGLK--VARALNRLG-----GGPALVNMIN---G----LKAYYISAFNANPTVLDAVTDI---ITG-SPTG-----Y--VS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------