@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : HRG1_HUMAN: (2015-12-08 )
MAPSRLQLGLRAAYSGISSVAGFSIFLVWTVVYRQPGTAAMGGLAGVLALWVLVTHVMYMQDYWRTWLKGLRGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISFKWAFLLSLYAHRYRADFADISILSDF
Atome Classification :
(16 SA)
-------------------------------------------------------------------------------------------------------------------------------.........10.....-----...20......-..30.....-...40........-50...-----.....60--........70........80-----.........90.....--...100.--.....----.-110...----....120.......130..-.------------------...---.140....------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------MA
P
S
R
L
Q
L
G
L
R
A
A
Y
S
G
-----
I
S
S
VA
G
F
S
I
F
L
-
V
W
T
V
V
YRQP-G
T
A
A
M
G
G
L
A
G
V
L
A
-
L
W
V
L
V
-----
T
H
V
M
Y
M
Q
--
D
Y
W
R
T
W
L
K
G
L
R
G
F
F
F
V
G
V
L
------
F
S
A
V
S
I
A
A
F
C
T
F
L
V
L
A
--
I
TRHQSL--T
D
P
T
S
----
Y
-
Y
L
S
S
V
W
----
S
F
I
S
F
K
W
A
F
L
L
S
L
Y
A
H
R
Y
R-A------------------DFA---
D
I
S
ILSDF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
88.34
18%
-149
- C5 -
2CWO
-
P21_BYVU
A:
[1-177]
---------------------------------------------------------------------------------------------------------------------------M
K
F
F
L
K
D
G
E
T
S
R
A
L
S
R
S
E
S
L
-----
L
R
R
V
K
E
L
G
T
N
S
-
Q
Q
S
E
I
--
S
E
-
C
V
D
E
F
N
E
L
A
S
F
N
H
-
L
L
V
T
V
-----
E
H
R
E
W
M
E
--
Q
R
I
G
E
M
L
K
E
I
R
A
F
L
K
V
R
V
V
TPMHKE
T
A
S
D
T
L
N
A
F
L
E
E
Y
C
R
I
T
G
L
A
R
E
D
A
L
--
R
E
K
M
R
----
K
-
V
K
S
V
V
L
----
F
H
H
S
E
L
L
K
F
E
V
T
E
N
M
F
S
Y
T
-
E
------------------
L
L
K
LNL
S
L
R
V
I
S
S
Q
ILGMAI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
82.55
25%
-144
- C8 -
2BBD
8
?
A:
[1-323]
G
E
I
Y
T
E
T
L
Q
Q
T
Y
A
W
T
A
G
T
N
I
P
I
K
I
P
RNNFIR
K
I
R
V
Q
L
I
G
S
I
S
N
SGT
A
A
V
T
L
P
SAPFPYNLVQ
T
F
N
L
S
Y
EGSKTL
Y
S
V
S
G
T
G
L
G
I
L
M
Y
Y
T
T
K
GQNPAYPAPG
T
S
V
P
AS
G
S
V
N
L
N
V
M
W
E
F
D
LARFPATM
V
Q
N
I
I
L
S
I
L
T
G
Q
A
P
S
G
-----
V
S
I
N
A
S
F
Y
I
T
I
-
T
Y
E
R
V
T
A
Q
E
-
I
L
S
E
-
G
G
L
G
A
D
G
E
M
P
L
A
T
V
-----
L
P
K
V
I
E
I
--
P
T
F
N
--
V
P
A
S
S
A
P
I
H
V
A
Y
L
------
Q
P
G
---
Q
I
Y
K
R
Q
L
V
Y
V
--
I
N
S
T
S
G
I
NN
T
D
P
T
E
----
Y
-
E
L
K
I
V
R
GVPT
D
K
I
K
V
S
W
A
A
L
Q
A
E
N
Q
A
E
Y
Q
V
A
------------------
P
Y
S
---
G
A
S
A
I
I
D
F
R
K
Y
F
NGDLDLTHAPSDS
I
E
Y
D
L
A
L
QNQ
D
N
V
Y
S
L
Y
V
S
Y
V
L
PY
Y
D
Q
L
A
AL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
81.94
13%
-131
* C8 *
1TTE
-
UBC1_YEAST
A:
[1-215]
------------------------------------------------------------------------------------------------------------------------------S
S
R
A
K
R
I
M
K
E
I
Q
A
V
K
D
D
PAAH
I
T
L
E
F
V
S
E
S
D
I
H
-
H
L
K
G
T
F
L
G
P
P
G
T
P
Y
E
G
G
K
F
V
V
D
I
-
E
V
P
M
E
YPF
K
P
P
K
M
Q
F
D
T
--
K
V
Y
H
P
N
I
S
S
V
T
G
A
I
C
L
D
I
L
RNA---
W
S
P
V
I
T
L
K
S
A
L
I
S
L
Q
A
--
L
L
Q
S
P
E
P
--
N
D
P
Q
D
----
A
-
E
V
A
Q
H
Y
----
L
R
D
R
E
S
F
N
K
T
A
A
L
W
T
R
L
Y
A
-
S
ETSNGQKGNVEESDLYGI
D
H
D
---
L
I
D
E
F
E
S
Q
GFE
K
D
K
I
V
E
V
L
R
R
LGVKSLDPNDN
N
T
A
N
R
I
I
E
E
L
LK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
80.77
25%
-101
* C7 *
1EFN
-
NEF_HV1BR
B:
[18-150]
-----------------------------------------------------------------------------------------------------------------------------------
R
P
Q
V
P
L
R
P
--
M
T
-----
Y
K
A
A
V
D
L
S
H
F
L
-
K
E
K
------------
G
G
L
E
G
L
I
-------------
H
S
Q
R
R
Q
--
D
I
L
D
L
W
I
Y
H
T
Q
G
Y
F
-----------------
P
D
W
Q
N
Y
-------
T
P
G
P
G
V
--
R
Y
P
L
T
FGWC
Y
-
K
L
V
P
V
R
----
E
V
L
E
W
R
F
D
S
R
L
A
-
F
H
H
V
A
R
-
E
------------------
L
H
P
---
E
Y
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
76.37
13%
-123
- C6 -
3Q87
-
?
A:
[1-125]
-------------------------------------------------------------------------------------------------------------------------------
M
K
P
F
L
L
G
L
-
L
K
C
K
R
C
S
-----
F
M
T
----
K
L
I
L
-
E
C
E
K
A
E
S
N
D
-
V
D
V
K
------------
I
F
N
-----
K
H
M
F
T
E
N
GG
E
R
L
K
S
L
V
N
S
L
R
D
F
H
--
G
R
E
------
L
S
E
Q
D
I
S
S
F
V
E
N
-------
P
G
D
D
E
K
--
I
K
E
F
L
----
F
-
G
I
D
V
V
E
----
G
S
L
R
C
D
M
C
G
L
I
Y
P
I
K
G
S
I
V
-
E
------------------
T
V
D
---
T
V
E
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
74.55
17%
-105
- C7 -
4WWX
-
RAG1_MOUSE
B:
[1-618]
----------------------------------------------------------------------------------APRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLF
L
L
A
L
R
A
R
N
E
H
R
Q
A
D
E
L
-----
E
A
I
M
Q
G
------------
R
G
S
-
G
L
Q
P
A
V
C
L
A
I
R
V
N
-
T
F
L
S
C
-----
S
Q
Y
H
K
M
Y
--
R
T
V
K
A
-
I
T
G
R
Q
I
F
Q
P
L
H
A
L
------
R
N
A
E
K
V
L
L
P
G
Y
H
P
F
E
W
--
Q
P
P
L
K
N
V
--
S
S
R
T
D
----
V
G
I
I
D
G
L
S
----
G
L
A
S
S
V
D
E
Y
P
V
D
T
I
A
K
R
F
R
-
Y
------------------
D
S
A
---
L
V
S
A
L
M
D
M
EEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA
10
HHSearch
50.53
13%
-80
* C9 *
3HD6
1
RHCG_HUMAN
A:
[280-325]
--------------------------------------------------------------------------------------------------------------------------------------
G
K
L
D
M
V
H
I
Q
-----
N
A
T
L
A
G
G
V
A
V
G
T
A
A
E
M
M
L
M
P
Y
-
G
A
L
I
I
G
F
V
C
G
I
I
S
-
T
L
G
F
V
-----
Y
L
T
P
F
L
E
--
S
R
L
H
I
Q
D
T
C
G
I
N
N
L
H
G
I
P
G
------
I
I
G
G
I
V
G
A
V
T
A
A
S
D
W
T
--
A
R
T
Q
G
K
F
--
Q
I
Y
G
L
----
L
-
V
T
L
A
M
A
----
L
M
G
G
I
I
V
G
L
I
L
R
L
P
F
W
G
Q
P
-
S
------------------
D
E
N
---
C
F
E
D
A
V
Y
W
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
48.11
14%
-91
- C9 -
2B2H
-
?
A:
[246-288]
------------------------------------------------------------------------------------------------------------------------------------------
S
L
G
I
V
-----
S
G
A
I
A
G
L
A
A
I
T
-
P
A
A
G
F
V
D
V
K
-
G
A
I
V
I
G
L
V
A
G
I
V
C
-
Y
L
A
M
D
-----
F
R
I
K
K
K
I
--
D
E
S
L
D
A
W
A
I
H
G
I
G
G
L
W
G
S
V
------
A
V
G
I
L
A
N
P
E
V
N
G
Y
A
G
L
--
L
F
G
N
P
Q
L
--
L
V
S
Q
L
----
I
-
A
V
A
S
T
T
----
A
Y
A
F
L
V
T
L
I
L
A
K
A
V
D
A
A
V
G
-
L
------------------
R
V
S
---
S
Q
E
E
Y
V
G
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
38.83
40%
487
- C2 -
1KDX
-
CREB1_RAT
B:
[133-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
R
-
K
------------------
I
L
N
---
D
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
38.25
37%
39
- C9 -
3J1Z
-
?
P:
[44-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
--
T
D
S
F
A
----
D
-
T
L
A
S
I
I
----
N
F
I
A
I
R
Y
A
I
V
P
A
D
H
D
H
R
Y
G
-
H
------------------
G
K
A
---
E
P
L
A
A
L
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
37.41
18%
-102
- C9 -
3WMM
-
?
A:
[16-48]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
-
R
R
V
L
V
S
I
V
A
F
-
Q
I
-
V
L
G
L
L
-----
I
H
M
I
V
L
S
--
T
D
L
-
N
W
L
D
D
N
I
P
V
S
Y
Q
A
L
G
------
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
28.10
21%
182
- C9 -
2BZW
-
B:
[99-112]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
A
A
Q
R
Y
G
-
R
------------------
E
L
R
---
R
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
25.38
40%
354
- C4 -
3BRV
-
IKKB_HUMAN
A:
[733-742]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
T
A
L
D
W
S
W
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
25.11
13%
111
- C9 -
2LKE
-
A:
[2-17]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
F
F
K
R
Q
Y
K
-
D
------------------
M
M
S
---
E
G
G
P
P
G
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
19.50
0%
235
- C3 -
1V54
-
COX6C_BOVIN
I:
[29-38]
--------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
L
G
F
A
T
-
F
Y
K
F
A
V
A
E
K
-
R
K
K
A
Y
A
D
F
Y
R
N
Y
D
-
S
M
K
D
F
-----
E
E
M
R
K
A
G
--
I
F
Q
S
A
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
3.31
29%
1828
- C1 -
1B4G
-
KCNC4_HUMAN
A:
[5-11]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
V
S
----
S
Y
R
G
R
K
S
G
N
K
P
P
S
K
T
C
L
K
E
-
E
------------------
M
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------