Atome 2 Filter

@TOME V2.2
(Nov 2016)

Ref. - Doc.

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Values color: [ Good | Correct | Middling | Bad ]

Sequence color : MutatedHelixStrandConserved

Query sequence : S2545_HUMAN: (2015-12-09 )
MPVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRWWG

Atome Classification :

	(20 SA)									--------------.........10..---..------....20........--30.--------.------------.----------.------------....40.......-.50.......------.60--..----------.--..-------....70........80........90.-------.......---100...------....110-----.......--------------.120.......130--------.....-..140....-----...150--------.........--160...----------....170--........180----.--.....-------.--.190....-.-----..200.......210.--...------------------...---.220-----.........230.---..---..---..240......-.-250...--...-.260--------........270........--------280......-------------------------------------------------
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		--------------MPVEEFVAGWISG---AL------GLVLGHPFDTVKVR--LQT--------Q------------T----------T------------YRGIVDCMVKIYR-HESLLGFFKG------MS---FP----------I--AS-------IAVVNSVLFGVYSNTLLVLTATSHQER-------RAQPPSY---MHIFLA------GCTGGF------LQAYCLA--------------PFDLIKVRLQNQTE--------PRAQP-GSPPPRYQG-----PVHC----------AASIFREEG--PRGLFR----------GAWALT---LRDTPTVGIY-----F--ITYEG-------L--CRQYTPEG-Q-----NPSSATVLVAGGF-AG--IAS------------------WVA---AT-------PLDMIKSRMQMDG---LR---RR---VYQGMLDCMVS-S-IRQEGL--GVF-FR-G--------VTINSARAFP-VNAVTFLS--------YEYLLRWWG-------------------------------------------------
27	Fugue	76.14	21%	-96	* C6 *	1LVO	-	R1AB_CVPPU (first)	A:[1-299]	----SGLRKMAQPSGLVEPCIVRVSYGNNVLN------GLWLG---DEVICP--RHV--------I------------A----------S------------DTT------RVIN-YENEMSSVRL------HN---FS----------V--SK-------NNVFLGVVSARYKGVNLVLKVN--QVN-------PNTPEHK---FKSIKA------GESFNI------LACYEGC--------------PGSVYGVNMRSQGT--------IKGSF-IAG-------------TC----------GSVGYVLEN--GILYFV----------YMHHLE---LGNGSHVGSN-----FEGEMYGG-------YEDQPSMQLEG-T-----NVMSSDNVVAFLY-AA--LINGERWFVTNTSMSLESYNTWAK---TN-------SFTELSSTDAFSM---LA---AK---TGQSVEK-LLD-S-IVRLNK--G---FG-G--------RTILSYGSLC-DE----FT--------PTEVIRQMYGV-----------------------------------------------
13	HHSearch	74.62	21%	-66	- C7 -	1OKC		ADT1_BOVIN	A:[7-293]	---------------FLKDFLAGGVAA---AI------SKTAVAPIERVKLL--LQV--------Q------------H----------ASKQISAEKQ---YKGIIDCVVRIPK-EQGFLSFWRG------NL---AN----------V--IR-------YFPTQALNFAFKDKYKQIFLGGVDRH--------KQFWRYF---AGNLAS------GGAAGA------TSLCFVY--------------PLDFARTRLAADVG--------KG-----AAQREFTG-----LGNC----------ITKIFKSDG--LRGLYQ----------GFNVSV---QGIIIYRAAY-----F--GVYDT-------A--KGMLPDPK-------NVHIIVSWMIAQT-VT--AVA------------------GLV---SY-------PFDTVRRRMMMQS---GRKGADI---MYTGTVDCWRK-I-AKDEGP--KAF-FK-G--------AWSNVLRGMG--GAFVLVL--------YDEI------------------------------------------------------
22	Fugue	70.40	21%	-67	- C7 -	1OKC		ADT1_BOVIN	A:[2-293]	----------DQALSFLKDFLAGGVAA---AI------SKTAVAPIERVKLL--LQV--------Q------------HASKQISAEK-Q------------YKGIIDCVVRIPK-EQGFLSFWRG------NL---AN----------V--IR-------YFPTQALNFAFKDKYKQIFL-GGVDRH-------KQFWRYF---AGNLAS------GGAAGA------TSLCFVY--------------PLDFARTRLAADV------------GK-GAAQREFTG-----LGNC----------ITKIFKSDG--LRGLYQ----------GFNVSV---QGIIIYRAAY-----F--GVYDT-------A--KGML-PDP-K-----NVHIIVSWMIAQT-VT--AVA------------------GLV---SY-------PFDTVRRRMMMQSGRKGA---DI---MYTGTVDCWRK-I-AKDEGP--KAF-FK-G--------AWSNVLRGMG--GAFVLVL--------YDEI------------------------------------------------------
2	PsiBlast_PDB	67.91	24%	-74	- C7 -	1OKC		ADT1_BOVIN	A:[8-279]	----------------LKDFLAGGVAA---AI------SKTAVAPIERVKLL--LQV--------QHASKQISAE---K----------Q------------YKGIIDCVVRIPK-EQGFLSFWRGNLANVIRY---FP----------T--QA-------L---NFAFKDKYKQIFL-----GGVDR-------HKQFWRY---FAGNLA------SGGAAG------ATSLCFVY-------------PLDFARTRLAADVG------------K-GAAQREFTG-----LGNC----------ITKIFKSDG--LRGLYQ----------G-FNVS---VQG---IIIY-----R--AAYFG-------V--YDTAKGML-P-----DPKNVHIIVSWMI-AQ--TVT------------------AVAGLVSY-------PFDTVRRRMMMQS---GR---KGADIMYTGTVDCWRK-I-AKDEGP--KAF-FK-G--------AWSNVLRGMG-GAFVLVLY--------DEI-------------------------------------------------------
3	PsiBlast_PDB	66.49	24%	-73	- C7 -	2C3E		ADT1_BOVIN	A:[8-279]	----------------LKDFLAGGVAA---AI------SKTAVAPIERVKLL--LQV--------QHASKQISAE---K----------Q------------YKGIIDCVVRIPK-EQGFLSFWRGNLANVIRY---FP----------T--QA-------L---NFAFKDKYKQIFL-----GGVDR-------HKQFWRY---FAGNLA------SGGAAG------ATSLCFVY-------------PLDFARTRLAADVG------------K-GAAQREFTG-----LGNC----------ITKIFKSDG--LRGLYQ----------G-FNVS---VQG---IIIY-----R--AAYFG-------V--YDTAKGML-P-----DPKNVHIIVSWMI-AQ--TVT------------------AVAGLVSY-------PFDTVRRRMMMQS---GR---KGADIMYTGTVDCWRK-I-AKDEGP--KAF-FK-G--------AWSNVLRGMG-GAFVLVLY--------DEI-------------------------------------------------------
6	PsiBlast_PDB	63.45	21%	-73	- C7 -	4C9H		ADT2_YEAST	A:[26-294]	------------------DFLMGGVSA---AV------AKTAASPIERVKLL--IQN--------Q------------DEMLKQGTLDRK------------YAGILDCFKRTAT-QEGVISFWRG------NT---AN----------V--IR-------YFPTQALNF-AFKDKIKAMFGFKKEEG-------YAKW--F---AGNLAS------GGAAGA------LSLLFVY--------------SLDYARTRLAADS----------------AR--QFNG-----LIDV----------YKKTLKSDG--VAGLYR----------GFLPSV---VGIVVYRGLY-----F--GMYDS-------L-----------------K-------------LASFLLG------------------WVV---TTGASTCSYPLDTVRRRMMMTS---GQ---AV---KYDGAFDCLRK-I-VAAEGV--GSL-FK-G--------CGANILRGVA-GAGVISMY--------DQLQMILFG-------------------------------------------------
5	PsiBlast_PDB	63.44	21%	-74	- C7 -	4C9Q		ADT3_YEAST	A:[30-299]	------------------NFLMGGVSA---AI------AKTAASPIERVKIL--IQN--------QDEMIKQGTLD--K----------K------------YSGIVDCFKRTAK-QEGLISFWRG------NT---AN----------V--IR-------YFPTQALNFAFKDKIKLMF---GFKKE--------GYGKWF---AGNLAS------GGAAGA------LSLLFVY--------------SLDFARTRLAADAK--------S------AR--QFNG-----LTDV----------YKKTLKSDG--IAGLYR----------GFMPSV---VGIVVYRGLY-----F--GMFDS-------L-----------------KPL---------F-LASFLLG------------------WVV---TTGASTCSYPLDTVRRRMMMTS---GQ---AV---KYNGAIDCLKK-I-VASEGV--GSL-FK-G--------CGANILRSVA-GAGVISMY--------DQLQMILFG-------------------------------------------------
4	PsiBlast_PDB	62.55	21%	-69	- C7 -	4C9J		ADT3_YEAST	A:[30-299]	------------------NFLMGGVSA---AI------AKTAASPIERVKIL--IQN--------QDEMIKQGTLD--K----------K------------YSGIVDCFKRTAK-QEGLISFWRG------NT---AN----------V--IR-------YFPTQALNFAFKDKIKLMF---GFKKE-------EGYGKWF---AGNLAS------GGAAGA------LSLLFVY--------------SLDFARTRLAADAK--------S------AR--QFNG-----LTDV----------YKKTLKSDG--IAGLYR----------GFMPSV---VGIVVYRGLY-----F--GMFDS-------L-----------------K---------------F-LLG------------------WVV---TTGASTCSYPLDTVRRRMMMTS---GQ---AV---KYNGAIDCLKK-I-VASEGV--GSL-FK-G--------CGANILRSVA-GAGVISMY--------DQLQMILFG-------------------------------------------------
25	Fugue	61.55	23%	-124	- C1 -	1Q9J	-	PAPA5_MYCTU	A:[1-418]	--------------MFPGSVIRKLSHS---EE------VFAQYEVFTSMTIQ--LRG--------V------------I----------D------------VDALSDAFDALLETHPVLASHLEQ------SSDGGWN----------L--VADDLLHSGICVIDAELRLDQSVSLLHLQLI-LREG-------GAELTLY---LHHCMADGHHGAVLVDEL------FSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIR--------KAERF-MSVMYAYPGLPQAVPVTRLWLSKQQTSDLMAFGREHRLSLNAVVA----------AAILLTEWQLRNTPHVPIP-----Y--VYPVD-------L---RFVLAPP-V-----APTEAT-----NL-LG--AAS------------------YLA---E------------IGPNTDIVD---LA---SD---IVATLRADLANGV-IQQSGLHFGTA-FE-GTPPGLPPLVFCTDATSFPTMRTPPGLE--------IEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEPGKSLEAIRSLLCTVPSEYG
12	HHSearch	61.47	28%	-74	- C7 -	2LCK	-	UCP2_MOUSE	A:[14-298]	----------------TVKFLGAGTAA---CI------ADLITFPLDTAKVR--LQI--------Q------------G----------ESQGLVRTAASAQYRGVLGTILTMVR-TEGPRSLYNG------LV---AG----------L--QR-------QMSFASVRIGLYDSVKQFYTKGS-------------EHAGI---GSRLLA------GSTTGA------LAVAVAQ--------------PTDVVKVRFQAQAR--------AG------GGRRYQS-----TVEA----------YKTIAREEG--IRGLWK----------GTSPNV---ARNAIVNCAE-----L--VTYDL-------I--KDTLLKANLM-----TDDLPCHFTSAFG-AG--FCT------------------TVI---AS-------PVDVVKTRYMNSA---L-----G---QYHSAGHCALT-M-LRKEGP--RAF-YK-G--------FMPSFLRLGS-WNVVMFVT--------YEQLKRALM-------------------------------------------------
1	PsiBlast_PDB	61.41	26%	-75	- C7 -	2LCK	-	UCP2_MOUSE	A:[16-296]	------------------KFLGAGTAA---CI------ADLITFPLDTAKVR--LQI--------QGESQGLVRTAASA----------Q------------YRGVLGTILTMVR-TEGPRSLYNG------LV---AG----------L--QR-------QMSFASVRIGLYDSVKQFYTKGSEH-------------AGI---GSRLLA------GSTTGA------LAVAVAQ--------------PTDVVKVRFQAQ----------ARAGG-GR---RYQS-----TVEA----------YKTIAREEG--IRGLWK----------GTSPNV---ARNAIVNCAE-----L--VTYDL-------I--KDTLLKAN-L-----MTDDLPCHFTSAFGAG--FCT------------------TVI---AS-------PVDVVKTRYMNSA---LG---Q-----YHSAGHCALT-M-LRKEGP--RAF-YK-G--------FMPSFLRLGS-WNVVMFVT--------YEQLKRALM-------------------------------------------------
24	Fugue	59.54	15%	-94	- C4 -	4MT7	-	ARHG9_RAT	A:[96-432]	QNRDQMRANVINEIMSTERHYIKHLKD---IC------EG----YLKQCRKRRDMFS--------D------------E----------Q------------LKVIFGNIEDIYR-FQ--MGFVRD------LE---KQYNNDDPHLSEI--GP-------CFLEHQDGFWIYSEYCNNHLDACMELS-------KLMKDSR---YQHFFE------ACRLLQQMIDIAIDGFLLT--------------PVQKI-CKYPLQLA--------ELLKY-TAQDHSDYR-----YVAA----------ALAVMRNVT--QQINERKRRLENIDKIAQWQAS---VLDWEGDDILDRSSEL--IYTGE-------M--AWIYQPYG-R-----NQQRVFFLFDHQM-VL--CKK------------------DLI---RR-------DILYYKGRIDMDK---YE---VI---DIEDGRD----------DDF--NVS-MKNA--------FKLHNKETEE-VHLFFAKK--------LEEKIRWLRAFREERKMVQEDEKIG---------------------------------
15	HHSearch	56.38	24%	-67	- C7 -	1OKC		ADT1_BOVIN	A:[4-201]	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSF---LKDFLA------GGVAAA------ISKTAVA--------------PIERVKLLLQVQHA--------SKQI---SAEKQYKG-----IIDC----------VVRIPKEQG--FLSFWR----------GNLANV---IRYFPTQALN-----F--AFKDK-------Y--KQIFLGGV-DRHKQFWRYFAGNLASGGA-AG--ATS------------------LCF---VY-------PLDFARTRLAADV---GKGAAQR---EFTGLGNCITK-I-FKSDGL--RGL-YQ-G--------FNVSVQGIII-YRAAYFGV--------YDTAKGMLP-------------------------------------------------
14	HHSearch	48.12	26%	-55	- C7 -	2LCK	-	UCP2_MOUSE	A:[15-204]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKFLG------AGTAAC------IADLITF--------------PLDTAKVRLQIQGE--------SQGLVRTAASAQYRG-----VLGT----------ILTMVRTEG--PRSLYN----------GLVAGL---QRQMSFASVR-----I--GLYDS-------V--KQFYTKGS-E-----HAGIGSRLLAGST-TG--ALA------------------VAV---AQ-------PTDVVKVRFQAQA---RAGG-GR---RYQSTVEAYKT-I-AREEGI--RGL-WK-G--------TSPNVARNAI-VNCAELVT--------YDLIKDTLL-------------------------------------------------
26	Fugue	46.01	11%	-76	- C5 -	3J9T	-	VA0D_YEAST	Q:[1-345]	----MEGVYFNIDNGFIEGVVRGYRNG---LLSNNQYINLTQCDTLEDLKLQ--LSSTDYGNFLSS------------V----------S------------SESLTTSLIQEYA-SSKLYHEFNY------IR---DQ----------SSGST-------RKFMDYITYGYMIDNVALMITGTIHDRDKGEILQRCHPLGWFDTLPTLSV------ATDLES------LYETVLV--------------DTPLAPYFKNCFDTAEELDDMNIEIIR-NKLYKAYLE-----DFYN----------FVTEEIPEP--AKECMQ----------TLLGFE---A-DRRSINIA-----L--NSLQSSDIDPDLK--SDLLPNIG-K-----LYPLATFHLAQAQ-DF--EGV------------------RAA---LA-------NVYEYRGFLETGN---LE---DH---FYQLEMELCRD-AFTQQFAI--STV-WA-W--------MKSKEQEVRN-ITWIAECIAQNQRERINNYISVY---------------------------------------------------
28	Fugue	41.85	10%	-80	- C6 -	1G0S	-	ADPP_ECOLI	A:[1-209]	--------------MLKPDNLPVTFG------------------KNDVEIIA--RET--------L------------Y----------R------------GFFSLDLYRFRHR-LFNGQMSHEV------RR---EI----------F--ER-------GHAAVLLPFDPVRDEVVLIEQIRIAAY-------DTSETPW---LLEM-------------------------------------------------------------------V-AGMIEEGES-----VEDV----------ARREAIEEA----------------------------------GLI-----V--KRTKP-------V--LSFLASPG-G-----TSERSSIMVGE--------VD------------------ATT---AS-------NEDIRVHVVSREQ---AY---QW---VEEG-----------------------------------KIDNAASVI-ALQWLQLH--------HQALKNEWA-------------------------------------------------
8	PsiBlast_PDB	38.29	27%	-40	- C7 -	4AFY		?	A:[56-146]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYEV-------L--LRLLNPQG-Q-----EVPPAEFLHAAKE-AG--LAEKIDR--------------WVI---LN-------SIKLLAEH---------R---AK---GHQTKLFVHLS-S-ASLQDP--GLLPWL-G--------VALKAARLPP-ESLVFQIS--------EADATSYLK-------------------------------------------------
11	PsiBlast_PDB	37.51	27%	-39	- C7 -	3HV8		?	A:[50-140]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYEV-------L--LRLLNPQG-Q-----EVPPAEFLHAAKE-AG--LAEKIDR--------------WVI---LN-------SIKLLAEH--------------------QTKLFVHLS-S-ASLQDP--GLLPWL-G--------VALKAARLPP-ESLVFQIS--------EADATSYLK-------------------------------------------------
10	PsiBlast_PDB	37.06	27%	-39	- C7 -	3HV9		?	A:[47-137]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYEV-------L--LRLLNPQG-Q-----EVPPAEFLHAAKE-AG--LAEKIDR--------------WVI---LN-------SIKLLAEH---------R---AK---GHQTKLFVHLS-S-ASLQDP--GLLPWL-G--------VALKAARLPP-ESLVFQIS--------EADATSYLK-------------------------------------------------
9	PsiBlast_PDB	36.29	27%	-36	- C7 -	4AG0	-	?	A:[56-146]	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYEV-------L--LRLLNPQG-Q-----EVPPAEFLHAAKE-AG--LAEKIDR--------------WVI---LN-------SIKLLAEH---------R---AK---GHQTKLFVHLS-S-ASLQDP--GLLPWL-G--------VALKAARLPP-ESLVFQIS--------EADATSYLK-------------------------------------------------